Search filters

List of works by José Alcamí

3-Phenylcoumarins as inhibitors of HIV-1 replication.

scientific article

4-Phenylcoumarins as HIV transcription inhibitors.

scientific article

5-Hydroxytyrosol inhibits HIV-1 replication in primary cells of the lower and upper female reproductive tract

scientific article published on 7 March 2017

A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity.

scientific article published on 24 May 2011

A new strategy based on recombinant viruses for assessing the replication capacity of HIV-1

scientific article published on 21 January 2008

A novel factor distinct from E2F mediates C-MYC promoter activation through its E2F element during exit from quiescence.

scientific article

A sensitive phenotypic assay for the determination of human immunodeficiency virus type 1 tropism.

scientific article published on 14 October 2010

A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity.

scientific article

A small-molecule inhibitor of HIV-1 Rev function detected by a diversity screen based on RRE-Rev interference

article

A therapeutic dendritic cell-based vaccine for HIV-1 infection

scientific article published on 13 January 2011

An Efficient Microarray-Based Genotyping Platform for the Identification of Drug-Resistance Mutations in Majority and Minority Subpopulations of HIV-1 Quasispecies

scientific article

Analysis of Non-AIDS-Defining Events in HIV Controllers

scientific article published in March 2016

Analysis of protein kinase C theta inhibitors for the control of HIV-1 replication in human CD4+ T cells reveals an effect on retrotranscription in addition to viral transcription.

scientific article published on 27 February 2015

Antagonistic modulation of human cytomegalovirus replication by transforming growth factor beta and basic fibroblastic growth factor.

scientific article

Anti-HIV activity of medicinal plant extracts

article

Anti-HIV activity of some synthetic lignanolides and intermediates.

scientific article published in September 2004

Anti-HIV activity of stilbene-related heterocyclic compounds

scientific article published on 18 May 2006

Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation

scientific article published on 31 March 2020

Application of proteomics technology for analyzing the interactions between host cells and intracellular infectious agents.

scientific article published on February 2008

Association between stromal cell-derived factor 1 chemokine gene variant and radiographic progression of rheumatoid arthritis

scientific article published on 01 January 2005

Basal shuttle of NF-kappaB/I kappaB alpha in resting T lymphocytes regulates HIV-1 LTR dependent expression.

scientific article

Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen

scientific article published on 16 February 2016

Broadly Neutralizing Antibodies and their Significance for HIV-1 Vaccines ⬇️

scientific article published on December 1, 2010

CCR5 genotype and HIV-1 infection in perinatally-exposed infants

scientific article published on 01 January 1999

CCR5 structural plasticity shapes HIV-1 phenotypic properties

article

CD11b-bearing mononuclear leucocytes and IgA levels in the staging of human immunodeficiency virus infection

scientific article published on April 15, 1992

CXCL12 gene expression is upregulated by hypoxia and growth arrest but not by inflammatory cytokines in rheumatoid synovial fibroblasts

scientific article published on 06 July 2010

Changes in the cellular microRNA profile by the intracellular expression of HIV-1 Tat regulator: A potential mechanism for resistance to apoptosis and impaired proliferation in HIV-1 infected CD4+ T cells

scientific article published on 2 October 2017

Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors.

scientific article

Chemokine expression by systemic sclerosis fibroblasts: abnormal regulation of monocyte chemoattractant protein 1 expression

scientific article published on 01 June 2001

Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers.

scientific article published on 28 February 2018

Clinical, virological and biochemical evidence supporting the association of HIV-1 reverse transcriptase polymorphism R284K and thymidine analogue resistance mutations M41L, L210W and T215Y in patients failing tenofovir/emtricitabine therapy

scientific article published on 13 August 2012

Conclusions and perspectives. Maraviroc

scientific article published in October 2008

Current situation of the pharmacogenetics of immune recovery in treated HIV-infected patients

scientific article

Dasatinib inhibits HIV-1 replication through the interference of SAMHD1 phosphorylation in CD4+ T cells

scientific article

Deep-Sequencing Analysis of the Dynamics of HIV-1 Quasiespecies in Naive Patients during a Short Exposure to Maraviroc.

scientific article published on 21 March 2018

Detection of Broadly Neutralizing Activity within the First Months of HIV-1 Infection.

scientific article published on 16 March 2016

Determination of HIV tropism and its use in the clinical practice

scientific article

Different Expression of Interferon-Stimulated Genes in Response to HIV-1 Infection in Dendritic Cells Based on Their Maturation State

scientific article

Dynamics of HIV replication in lymphocytes and the efficacy of protease inhibitors.

scientific article

Effect of mycophenolate mofetil on immune response and plasma and lymphatic tissue viral load during and after interruption of highly active antiretroviral therapy for patients with chronic HIV infection: a randomized pilot study.

scientific article published on July 2004

Ellagitannins from Tuberaria lignosa as entry inhibitors of HIV

article

Environmentally Friendly Procedure Based on Supercritical Fluid Chromatography and Tandem Mass Spectrometry Molecular Networking for the Discovery of Potent Antiviral Compounds from Euphorbia semiperfoliata.

scientific article published on 19 September 2017

Evaluation of resistance to HIV-1 infection ex vivo of PBMCs isolated from patients with chronic myeloid leukemia treated with different tyrosine kinase inhibitors

scientific article published on 22 August 2018

Evaluation of the Abbott LCx quantitative assay for measurement of human immunodeficiency virus RNA in plasma.

scientific article

Factors Leading to the Loss of Natural Elite Control of HIV-1 Infection.

scientific article published on 6 December 2017

Familial defect of CD3 (T3) expression by T cells associated with rare gut epithelial cell autoantibodies.

scientific article

Fas activation of a proinflammatory program in rheumatoid synoviocytes and its regulation by FLIP and caspase 8 signaling.

scientific article

Functional Consequences for Apoptosis by Transcription Elongation Regulator 1 (TCERG1)-Mediated Bcl-x and Fas/CD95 Alternative Splicing

scientific article published on 13 October 2015

G protein-dependent CCR5 signaling is not required for efficient infection of primary T lymphocytes and macrophages by R5 human immunodeficiency virus type 1 isolates

scientific article

Generation and characterization of a defective HIV-1 Virus as an immunogen for a therapeutic vaccine.

scientific article

Genetic analysis of the long terminal repeat (LTR) promoter region in HIV-1-infected individuals with different rates of disease progression

scientific article published on 09 December 2006

Genetic and phenotypic analyses of sequential vpu alleles from HIV-infected IFN-treated patients.

scientific article

Genomic organization and promoter characterization of human CXCR4 gene

scientific article

Gold nanoparticles capped with sulfate-ended ligands as anti-HIV agents.

scientific article published on 25 March 2010

Guatemalan plants extracts as virucides against HIV-1 infection.

scientific article published on 20 February 2008

Guidelines for cloning, expression, purification and functional characterization of primary HIV-1 envelope glycoproteins

scientific article published on 20 July 2016

HIV Research for Prevention 2018: From Research to Impact Conference Summary and Highlights

scientific article published on 29 May 2019

HIV-1 exploits CCR5 conformational heterogeneity to escape inhibition by chemokines

scientific article published on 21 May 2013

HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers

scientific article published on 16 December 2016

Hydroxytyrosol: a new class of microbicide displaying broad anti-HIV-1 activity

scientific article published on 24 September 2016

Hypoxia induces expression of the chemokines monocyte chemoattractant protein-1 (MCP-1) and IL-8 in human dermal fibroblasts

scientific article

IL-7 Induces SAMHD1 Phosphorylation in CD4+ T Lymphocytes, Improving Early Steps of HIV-1 Life Cycle.

scientific article published on 23 February 2016

Identification of Immunological Parameters as Predictive Biomarkers of Relapse in Patients with Chronic Myeloid Leukemia on Treatment-Free Remission

scientific article published on 25 December 2020

Immune activation promotes evolutionary conservation of T-cell epitopes in HIV-1.

scientific article

Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway

scientific article published on 24 June 2004

In vitro analysis of synergism and antagonism of different nucleoside/nucleotide analogue combinations on the inhibition of human immunodeficiency virus type 1 replication.

scientific article

In vitro selective elimination of HIV-infected cells from peripheral blood in AIDS patients by the immunotoxin DAB389CD4 ⬇️

scientific article published on May 28, 1998

Indomethacin in the relief of AIDS symptoms

scientific article published on 01 September 1986

Induction of an endothelial cell growth factor by human cytomegalovirus infection of fibroblasts

scientific article published on 01 November 1991

Insight in miRNome of Long-Term Non-Progressors and Elite Controllers Exposes Potential RNAi Role in Restraining HIV-1 Infection

scientific article published on 31 July 2020

International network for comparison of HIV neutralization assays: the NeutNet report

scientific article

International network for comparison of HIV neutralization assays: the NeutNet report II

scientific article (publication date: 2012)

Intracellular expression of Tat alters mitochondrial functions in T cells: a potential mechanism to understand mitochondrial damage during HIV-1 replication

scientific article

Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells

scientific article published on 27 May 2015

Isolation, Structural Modification, and HIV Inhibition of Pentacyclic Lupane-Type Triterpenoids from Cassine xylocarpa and Maytenus cuzcoina.

scientific article published on 30 April 2015

LTR and tat variability of HIV-1 isolates from patients with divergent rates of disease progression

scientific article

MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter.

scientific article published on September 2017

Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates.

scientific article

Mesuol, a natural occurring 4-phenylcoumarin, inhibits HIV-1 replication by targeting the NF-kappaB pathway.

scientific article published on 20 April 2005

Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon

scientific article

Modifications in host cell structure and functions mediated by Tat intracellular expression are greatly dependent on the second exon

Multivalent manno-glyconanoparticles inhibit DC-SIGN-mediated HIV-1 trans-infection of human T cells

scientific article published on 01 July 2009

NF-kappa B-dependent induction of the NF-kappa B p50 subunit gene promoter underlies self-perpetuation of human immunodeficiency virus transcription in monocytic cells ⬇️

scientific article published on August 15, 1992

Natural human antibodies retrieved by phage display libraries from healthy donors: polyreactivity and recognition of human immunodeficiency virus type 1gp120 epitopes.

scientific article published in September 1999

Negatively charged glyconanoparticles modulate and stabilize the secondary structures of a gp120 V3 loop peptide: toward fully synthetic HIV vaccine candidates.

scientific article published on 11 March 2015

Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways

scientific article published on 19 February 2017

New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection

scientific article

Olean-18-ene triterpenoids from Celastraceae species inhibit HIV replication targeting NF-kB and Sp1 dependent transcription.

scientific article

P04-18. Comparison of HIV neutralization assays for use in vaccine research and clinical trials, phase II: results from the NeutNet working group

article

PKCθ and HIV-1 Transcriptional Regulator Tat Co-exist at the LTR Promoter in CD4(+) T Cells.

scientific article published on 29 February 2016

Phylodynamics of SARS-CoV-2 transmission in Spain

scientific article published on 21 April 2020

Plasma stromal cell-derived factor (SDF)-1 levels, SDF1-3'A genotype, and expression of CXCR4 on T lymphocytes: their impact on resistance to human immunodeficiency virus type 1 infection and its progression

scientific article published on 13 September 2002

Potential role of tyrosine kinase inhibitors during primary HIV-1 infection.

scientific article published on 21 March 2017

Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets.

scientific article published on 18 April 2018

Protein kinase Ctheta is a specific target for inhibition of the HIV type 1 replication in CD4+ T lymphocytes.

scientific article

Quinoline-based compounds as modulators of HIV transcription through NF-kappaB and Sp1 inhibition.

scientific article published on 23 June 2010

Rate and predictors of progression in elite and viremic HIV-1 controllers.

scientific article published on 05 February 2016

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

scientific article published on 07 September 2020

Reverse transcriptase-like activity in Trypanosoma cruzi

scientific article published on 01 February 1997

SDF-1/CXCL12 production by mature dendritic cells inhibits the propagation of X4-tropic HIV-1 isolates at the dendritic cell-T-cell infectious synapse.

scientific article published on 24 February 2010

SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro

scientific article

Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).

scientific article published on 09 September 2011

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

scientific article published on 26 February 2015

Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

scientific article published on 24 October 2017

Structure-based design of an RNA-binding p-terphenylene scaffold that inhibits HIV-1 Rev protein function.

scientific article published on 8 November 2013

The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1

scientific article

The catalytic activity of dsRNA-dependent protein kinase, PKR, is required for NF-kappaB activation.

scientific article published in January 2001

The mutation of Transportin 3 gene that causes limb girdle muscular dystrophy 1F induces protection against HIV-1 infection

scientific article published on 29 August 2019

The pharmacology of HIV-1 antiretrovirals differs between macaques and humans

scientific article published on 17 June 2022

The presence of HIV-1 Tat protein second exon delays fas protein-mediated apoptosis in CD4+ T lymphocytes: a potential mechanism for persistent viral production

scientific article published on 30 January 2013

Therapeutic Immunization with Dendritic Cells Loaded with Heat‐Inactivated Autologous HIV‐1 in Patients with Chronic HIV‐1 Infection

article

Transcription elongation regulator 1 (TCERG1) regulates competent RNA polymerase II-mediated elongation of HIV-1 transcription and facilitates efficient viral replication.

scientific article published on 28 October 2013

Transcriptome Sequencing of Peripheral Blood Mononuclear Cells from Elite Controller-Long Term Non Progressors

scientific article published on 03 October 2019

Tyrosine kinase inhibitors: potential use and safety considerations in HIV-1 infection.

scientific article published on 7 April 2017

[Immunopathogenesis of HIV infection]

scientific article published on 01 March 2011

[Infectious diseases research]

scientific article published on 01 December 2008

[The HIV replication cycle. Established therapeutic targets and potential targets]

scientific article published on 01 November 2008

Paulina is supported by:

About Paulina

Help