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List of works by Garnett Kelsoe

A Functional Analysis of the Spacer of V(D)J Recombination Signal Sequences ⬇️

scientific article published on October 13, 2003

A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface

scientific article published on 01 June 2021

A birthday for B cells: Lymphopoiesis II, a scientific symposium honoring Max Cooper

scientific article published in December 2003

A novel role for Activation-induced cytidinedeaminase: Central B-cell tolerance ⬇️

scientific article published on October 15, 2011

A tribute to Michael S. Neuberger

scientific article

AID expression during B-cell development: searching for answers ⬇️

scientific article published on April 1, 2011

Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome

scientific article published on 10 August 2009

Activation-induced cytidine deaminase mediates central tolerance in B cells

scientific article

Alternative pathways for the selection of antigen-specific peripheral T cells

scientific article published in Nature

An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability

scientific article

An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1.

scientific article published on 10 March 2014

Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

scientific article

Antibody light-chain-restricted recognition of the site of immune pressure in the RV144 HIV-1 vaccine trial is phylogenetically conserved

scientific article

Antibody polyspecificity and neutralization of HIV-1: a hypothesis

scientific article

Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance

scientific article

Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies

B-cell-lineage immunogen design in vaccine development with HIV-1 as a case study

scientific article

BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance

scientific article published on February 2017

Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus

scientific article

Complex Antigens Drive Permissive Clonal Selection in Germinal Centers

scientific article published on 2 March 2016

Computational tools for understanding sequence variability in recombination signals

scientific article

Conserved cryptic recombination signals in Vkappa gene segments are cleaved in small pre-B cells

scientific article

Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies

scientific article

Cross-Reactivity to Kynureninase Tolerizes B Cells That Express the HIV-1 Broadly Neutralizing Antibody 2F5

scientific article published on 15 November 2019

Crystal structure of a non-neutralizing antibody to the HIV-1 gp41 membrane-proximal external region ⬇️

scientific article published on November 14, 2010

Curiouser and curiouser: the role(s) of AID expression in self-tolerance

scientific article published in October 2014

Differential reactivity of germ line allelic variants of a broadly neutralizing HIV-1 antibody to a gp41 fusion intermediate conformation

scientific article published on 14 September 2011

Disparate adjuvant properties among three formulations of "alum"

scientific article published on 29 November 2012

Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane

scientific article

Effects of acute and chronic inflammation on B-cell development and differentiation

scientific article published on February 2009

Efficient Culture of Human Naive and Memory B Cells for Use as APCs

scientific article published on 10 October 2016

Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes

scientific article published on 03 March 2014

Enhanced differentiation of splenic plasma cells but diminished long-lived high-affinity bone marrow plasma cells in aged mice

scientific article (publication date: February 2003)

Functional, non-clonal IgMa-restricted B cell receptor interactions with the HIV-1 envelope gp41 membrane proximal external region

scientific article

Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density

scientific article published on 2 March 2018

Germinal center responses to complex antigens

scientific article published on 01 July 2018

H3N2 influenza infection elicits more cross-reactive and less clonally expanded anti-hemagglutinin antibodies than influenza vaccination

scientific article (publication date: 2011)

HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development

scientific article

HIV-1 envelope induces memory B cell responses that correlate with plasma antibody levels after envelope gp120 protein vaccination or HIV-1 infection

scientific article

HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages

scientific article published on 2 May 2012

HIV-Host Interactions: Implications for Vaccine Design

scientific article

Heavy-chain receptor editing unbound

scientific article

Host controls of HIV broadly neutralizing antibody development

scientific article published on January 2017

Hypermutation in T cells questioned

scholarly article

IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria

scientific article

IL-1R type I-dependent hemopoietic stem cell proliferation is necessary for inflammatory granulopoiesis and reactive neutrophilia

scientific article

Identification and utilization of arbitrary correlations in models of recombination signal sequences

scientific article

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

scientific article published on November 2016

Identification of a tissue-specific, C/EBPβ-dependent pathway of differentiation for murine peritoneal macrophages

scientific article published on 27 September 2013

Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies

scientific article

Immune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies

scientific article

Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies

scientific article

Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses

scientific article published on 08 November 2019

Immunogenicity of membrane-bound HIV-1 gp41 membrane-proximal external region (MPER) segments is dominated by residue accessibility and modulated by stereochemistry.

scientific article

Immunoglobulin gene insertions and deletions in the affinity maturation of HIV-1 broadly reactive neutralizing antibodies

scientific article

Impaired social recognition memory in recombination activating gene 1-deficient mice

scientific article

Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier

article

Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow

scientific article

Inflammation controls B lymphopoiesis by regulating chemokine CXCL12 expression

scientific article published in January 2004

Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism

scientific article

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

scientific article

Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations ⬇️

scientific article published on 23 November 2017

Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages

scientific article published on April 2016

Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum

scientific article

Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice

scientific article published in January 2008

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

scientific article

Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires

scientific article published in January 2018

Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells

scientific article published on 10 March 2014

Minding the gap: The impact of B-cell tolerance on the microbial antibody repertoire

scientific article published on 27 September 2019

Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells

scientific article

Natural IgM is produced by CD5- plasma cells that occupy a distinct survival niche in bone marrow

scientific article

Outside influence: TLRs direct hematopoietic cell fates

scientific article published on June 2006

Plexin-D1 Is a Novel Regulator of Germinal Centers and Humoral Immune Responses ⬇️

scientific article published on 04 April 2011

Poly- and autoreactivity of HIV-1 bNAbs: implications for vaccine design.

scientific article published on 28 July 2018

Polyclonal B cell differentiation and loss of gastrointestinal tract germinal centers in the earliest stages of HIV-1 infection

scientific article

Polyreactivity and autoreactivity among HIV-1 antibodies

scientific article

Potent and broad HIV-neutralizing antibodies in memory B cells and plasma

scientific article published on January 2017

Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification

scientific article published on 2 November 2006

Prospective estimation of recombination signal efficiency and identification of functional cryptic signals in the genome by statistical modeling

scientific article

Recall of B cell memory depends on relative locations of prime and boost immunization

scientific article published in 2022

Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth

scientific article published on 19 November 2020

Reciprocal expansions of idiotypic and anti-idiotypic clones following antigen stimulation ⬇️

scientific article published on May 24, 1979

Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation

scientific article

Redemption of autoreactive B cells

scientific article

Rescue of HIV-1 broad neutralizing antibody-expressing B cells in 2F5 VH x VL knockin mice reveals multiple tolerance controls

scientific article

Role of germinal centers for the induction of broadly-reactive memory B cells

scientific article published on 26 March 2017

Role of immune mechanisms in induction of HIV-1 broadly neutralizing antibodies

scientific article

Self-tolerance curtails the B cell repertoire to microbial epitopes.

scientific article

Should we B-leavin' now?

scientific article

Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies.

scientific article published on March 2017

Stromal cell independent B cell development in vitro: generation and recovery of autoreactive clones

scientific article published on 28 January 2010

Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site

scientific article

T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells

scientific article

TSC1 Promotes B Cell Maturation but Is Dispensable for Germinal Center Formation

scientific article published on 22 May 2015

Targeted Elimination of Immunodominant B Cells Drives the Germinal Center Reaction toward Subdominant Epitopes

scientific article published in December 2017

The "dispensable" portion of RAG2 is necessary for efficient V-to-DJ rearrangement during B and T cell development

scientific article published on November 2002

The human fetal lymphocyte lineage: identification by CD27 and LIN28B expression in B cell progenitors

scientific article published on 30 July 2013

The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes

scientific article

Therapeutic CD154 antibody for lupus: promise for the future? ⬇️

scientific article published on November 1, 2003

Tracing Self-Reactive B Cells in Normal Mice

scientific article published on 15 May 2020

Transcriptome analysis of mouse stem cells and early embryos

scientific article

V(D)J recombinase-mediated processing of coding junctions at cryptic recombination signal sequences in peripheral T cells during human development

scientific article published in October 2006

Very low affinity B cells form germinal centers, become memory B cells, and participate in secondary immune responses when higher affinity competition is reduced

scientific article

What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Breaking through Immunity's Glass Ceiling

scientific article published on 19 June 2017

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