List of works by Carina Mallard

A Critical Review of Models of Perinatal Infection

scientific article published on 19 February 2015

A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses

scientific article published in 2012

A novel image segmentation method for the evaluation of inflammation-induced cortical and hippocampal white matter injury in neonatal mice

scientific article published in March 2019

A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury

scientific article published in January 1992

Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ischemic injury in late gestation fetal sheep.

scientific article published in May 1996

Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: restoring effects of inhibitors of HDACs, p38 MAPK and GSK3β

scientific article published in October 2011

Antenatal brain injury: aetiology and possibilities of prevention.

scientific article

Apoptotic mechanisms in the immature brain: involvement of mitochondria

scientific article published on 2 July 2009

Astrocytes and microglia in acute cerebral injury underlying cerebral palsy associated with preterm birth

scientific article published on 31 October 2013

Attenuation of reactive gliosis does not affect infarct volume in neonatal hypoxic-ischemic brain injury in mice

scientific article published on 28 April 2010

Bacterial endotoxin sensitizes the immature brain to hypoxic--ischaemic injury

scientific article published in March 2001

Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia.

scientific article published on 28 January 2015

Cell Death in the Developing Brain after Hypoxia-Ischemia

scientific article published on 23 August 2017

Cell therapy for neonatal hypoxia-ischemia and cerebral palsy

scientific article published in May 2012

Central and peripheral leptin and agouti-related protein during and after pregnancy in relation to weight change

scientific article published on 20 November 2017

Cerebellar white matter injury following systemic endotoxemia in preterm fetal sheep

scientific article published on 11 March 2009

Cerebral histologic and electrocorticographic changes after asphyxia in fetal sheep.

scientific article published in May 1992

Cerebrospinal fluid levels of insulin, leptin, and agouti-related protein in relation to BMI in pregnant women

scientific article published on 30 April 2016

Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro

scientific article published on 27 February 2013

Choroid plexus transcriptome and ultrastructure analysis reveals a TLR2-specific chemotaxis signature and cytoskeleton remodeling in leukocyte trafficking

scientific article published on 26 February 2019

Combined deficiency of IL-1beta18, but not IL-1alphabeta, reduces susceptibility to hypoxia-ischemia in the immature brain

scientific article published in March 2005

Combined effect of hypothermia and caspase-2 gene deficiency on neonatal hypoxic-ischemic brain injury

scientific article published on 9 February 2012

Corrigendum to “Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro” [Brain Behav. Immun. 24 (2010) 776–783]

scientific article published in January 2011

Death associated protein kinases: molecular structure and brain injury

scientific article published on 04 July 2013

Decreased survival of newborn neurons in the dorsal hippocampus after neonatal LPS exposure in mice

scientific article published on 30 August 2013

Delayed IGF-1 administration rescues oligodendrocyte progenitors from glutamate-induced cell death and hypoxic-ischemic brain damage.

scientific article published in January 2007

Delayed Peripheral Administration of a GPE Analogue Induces Astrogliosis and Angiogenesis and Reduces Inflammation and Brain Injury following Hypoxia-Ischemia in the Neonatal Rat

scientific article published in 2007

Delayed Vasodilation and Altered Oxygenation after Cerebral Ischemia in Fetal Sheep

scientific article published in January 1996

Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep.

scientific article published on 14 October 2011

Deletion of the c-Jun N-terminal kinase 3 gene protects neonatal mice against cerebral hypoxic-ischaemic injury.

scientific article published on 25 October 2006

Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury

scientific article published on 25 February 2009

Diabetes negatively affects cortical and striatal GABAergic neurons: an effect that is partially counteracted by exendin-4.

scientific article published on 25 October 2016

Disruption of interleukin-18, but not interleukin-1, increases vulnerability to preterm delivery and fetal mortality after intrauterine inflammation

scientific article published in September 2006

Does Caspase-6 Have a Role in Perinatal Brain Injury?

scientific article published on 24 March 2015

Dual TNFα-induced effects on NRF2 mediated antioxidant defence in astrocyte-rich cultures: role of protein kinase activation

scientific article published in December 2012

Dual role of intrauterine immune challenge on neonatal and adult brain vulnerability to hypoxia-ischemia

scientific article published in June 2007

ECG and heart rate variability changes in preterm and near-term fetal lamb following LPS exposure.

scientific article published on 2 May 2008

Editorial: White blood cells matter in neonatal white-matter injury

scientific article published in January 2016

Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders

scientific article published on 11 July 2017

Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia

scientific article published on 05 January 2017

Effect of inflammation on central nervous system development and vulnerability

scientific article published in April 2005

Effect of lipopolysaccharide on global gene expression in the immature rat brain

scientific article published on August 2006

Effects of chronic placental insufficiency on brain development in fetal sheep.

scientific article published in February 1998

Effects of intrauterine inflammation on the developing mouse brain

scientific article published on 30 January 2007

Electrocardiographic changes following umbilical cord occlusion in the midgestation fetal sheep.

scientific article published in February 2005

Elevated levels of circulating cell-free DNA and neutrophil proteins are associated with neonatal sepsis and necrotizing enterocolitis in immature mice, pigs and infants

scientific article published in January 2017

Endotoxin-induced hypoxic-ischemic tolerance is mediated by up-regulation of corticosterone in neonatal rat.

scientific article published on 2 December 2005

Exendin-4 reduces ischemic brain injury in normal and aged type 2 diabetic mice and promotes microglial M2 polarization

scientific article published on 7 August 2014

Exposure to prenatal carbon monoxide and postnatal hyperthermia: short and long-term effects on neurochemicals and neuroglia in the developing brain.

scientific article published in April 2000

Expression and subcellular localization of TLR-4 in term and first trimester human placenta.

scientific article published on February 2006

Expression of MMP-12 after neonatal hypoxic-ischemic brain injury in mice

scientific article published on 11 August 2009

Expression of the Nrf2-system at the blood-CSF barrier is modulated by neonatal inflammation and hypoxia-ischemia

scientific article published on 30 October 2012

Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P. hamadryas).

scientific article published on 16 June 2015

Fetal brain injury in experimental intrauterine asphyxia and inflammation in Göttingen minipigs

scientific article published in January 2006

Flinders sensitive line rats are resistant to infarction following transient occlusion of the middle cerebral artery

scientific article published on 16 March 2020

Flunarizine, a calcium channel antagonist, is partially prophylactically neuroprotective in hypoxic-ischemic encephalopathy in the fetal sheep.

scientific article

Frequent episodes of brief ischemia sensitize the fetal sheep brain to neuronal loss and induce striatal injury.

scientific article published in January 1993

From mice to women and back again: causalities and clues for Chlamydia-induced tubal ectopic pregnancy

scientific article published on 09 August 2012

GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling

scientific article published on 15 September 2015

Galectin-3 contributes to neonatal hypoxic-ischemic brain injury

scientific article published on 4 January 2010

Global Gene Expression in the Immature Brain After Hypoxia-Ischemia

scientific article published in December 2004

Global Gene Expression in the Immature Brain after Hypoxia-Ischemia

article

Global gene expression in the developing rat brain after hypoxic preconditioning: involvement of apoptotic mechanisms?

scientific article published on April 2007

Growth Hormone-Releasing Peptide Hexarelin Reduces Neonatal Brain Injury and Alters Akt/Glycogen Synthase Kinase-3β Phosphorylation

scientific article published in November 2005

High-field diffusion tensor imaging characterization of cerebral white matter injury in lipopolysaccharide-exposed fetal sheep

scientific article published on 5 June 2012

Hypoxic preconditioning confers long-term reduction of brain injury and improvement of neurological ability in immature rats.

scientific article published on 20 December 2004

IGF-I neuroprotection in the immature brain after hypoxia-ischemia, involvement of Akt and GSK3beta?

scientific article published in March 2005

Immune responses in perinatal brain injury.

scientific article published on 16 November 2016

Increased MMP-9 and TIMP-1 in mouse neonatal brain and plasma and in human neonatal plasma after hypoxia-ischemia: a potential marker of neonatal encephalopathy

scientific article published in January 2012

Increased vulnerability to neuronal damage after umbilical cord occlusion in fetal sheep with advancing gestation.

scientific article

Infection-induced inflammation and cerebral injury in preterm infants

scientific article published on 28 May 2014

Infection-induced vulnerability of perinatal brain injury

scientific article published on 2 November 2011

Inflammation during fetal and neonatal life: implications for neurologic and neuropsychiatric disease in children and adults

scientific article published on 14 February 2012

Inflammation-induced preconditioning in the immature brain

scientific article published on 26 February 2007

Inflammation-induced sensitization of the brain in term infants

scientific article published on April 2015

Inflammatory Gene Profiling in the Developing Mouse Brain After Hypoxia-Ischemia

scientific article published in December 2004

Inflammatory gene profiling in the developing mouse brain after hypoxia-ischemia

scientific article published on 01 December 2004

Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury

scientific article published in 2011

Innate defense regulator peptide 1018 protects against perinatal brain injury

scientific article published on 7 March 2014

Insulin-like growth factor-1 is a potent neuronal rescue agent after hypoxic-ischemic injury in fetal lambs

scientific article

Interaction of inflammation and hyperoxia in a rat model of neonatal white matter damage.

scientific article published on 14 November 2012

Intranasal C3a treatment ameliorates cognitive impairment in a mouse model of neonatal hypoxic-ischemic brain injury

scientific article published on 3 January 2017

Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia-ischemia

scientific article published on 18 December 2018

Learning and activity after irradiation of the young mouse brain analyzed in adulthood using unbiased monitoring in a home cage environment

scientific article published on 28 December 2010

Lipopolysaccharide induces both a primary and a secondary phase of sensitization in the developing rat brain

scientific article published on 5 May 2005

Lipopolysaccharide sensitizes neonatal hypoxic-ischemic brain injury in a MyD88-dependent manner

scientific article published on 16 November 2009

Lipopolysaccharide-induced inflammation and perinatal brain injury

scientific article published on 21 June 2006

Lymphocytes Contribute to the Pathophysiology of Neonatal Brain Injury.

scientific article published on 19 March 2018

Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection.

scientific article published in January 2017

Magnesium is not consistently neuroprotective for perinatal hypoxia-ischemia in term-equivalent models in preclinical studies: a systematic review

scientific article published on January 2014

Magnesium sulphate induces preconditioning in preterm rodent models of cerebral hypoxia-ischemia

scientific article published on 17 January 2018

Matrix metalloproteinase-9 gene knock-out protects the immature brain after cerebral hypoxia-ischemia.

scientific article published in February 2007

Maturational change in the cortical response to hypoperfusion injury in the fetal sheep.

scientific article published in May 1998

Maturational effects of lipopolysaccharide on white-matter injury in fetal sheep

scientific article published in December 2005

Mechanisms of perinatal brain damage and protective possibilities

scientific article published in December 2006

Melatonin reduces inflammation and cell death in white matter in the mid-gestation fetal sheep following umbilical cord occlusion

scientific article

Microglia and neonatal brain injury.

scientific article

Microglia toxicity in preterm brain injury

scientific article published on 21 April 2014

Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro

scientific article published on 10 November 2009

Mitochondria, Bioenergetics and Excitotoxicity: New Therapeutic Targets in Perinatal Brain Injury

scientific article published on 12 July 2017

Mitochondria: hub of injury responses in the developing brain.

scientific article published on February 2014

Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury.

scientific article published on 18 December 2017

Modeling Ischemia in the Immature Brain: How Translational Are Animal Models?

scientific article published on 13 August 2015

Models of white matter injury: comparison of infectious, hypoxic-ischemic, and excitotoxic insults

scientific article published in January 2002

Monosialoganglioside GM1 treatment after a hypoxic-ischemic episode reduces the vulnerability of the fetal sheep brain to subsequent injuries.

scientific article published in February 1994

Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury

scientific article published on 12 September 2018

N-acetylcysteine reduces lipopolysaccharide-sensitized hypoxic-ischemic brain injury

scientific journal article

NEUROBID--an EU-funded project to study the developing brain barriers

scientific article

NRF2-regulation in brain health and disease: implication of cerebral inflammation

scientific article published in April 2014

Neonatal Peripheral Immune Challenge Activates Microglia and Inhibits Neurogenesis in the Developing Murine Hippocampus

scientific article published in 2014

Neonatal microglia: The cornerstone of brain fate

scientific article published on 2 September 2016

Neurokinin 1 receptor signaling affects the local innate immune defense against genital herpes virus infection

scientific article published in November 2005

Neuronal damage in the developing brain following intrauterine asphyxia.

scientific article published on January 1995

Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury

scientific article published on 18 April 2012

Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury

scientific article published on 29 July 2010

New means to assess neonatal inflammatory brain injury

scientific article published in 2015

Nitric oxide synthase inhibition attenuates delayed vasodilation and increases injury after cerebral ischemia in fetal sheep.

scientific article

Outcome after ischemia in the developing sheep brain: an electroencephalographic and histological study

scientific article published on January 1, 1992

Partial neuroprotection with low-dose infusion of the alpha2-adrenergic receptor agonist clonidine after severe hypoxia in preterm fetal sheep

scientific article published on 18 May 2008

Pathological changes in the white matter after spinal contusion injury in the rat

scientific article published on 29 August 2012

Perinatal brain injury. Pathophysiology and therapeutic intervention.

scientific article published in September 1995

Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype

scientific article published on 17 March 2014

Peripheral myeloid cells contribute to brain injury in male neonatal mice

scientific article published on 30 October 2018

Pitfalls in the quest of neuroprotectants for the perinatal brain

scientific article published on 30 September 2011

Potential neuroprotective strategies for perinatal infection and inflammation

scientific article published on 19 February 2015

Preconditioning and the developing brain

scientific article published in December 2004

Preface

scientific article published in 2013

Radixin expression in microglia after cortical stroke lesion

scientific article published on 26 February 2013

Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury

scientific article published on 4 June 2013

Reduced number of neurons in the hippocampus and the cerebellum in the postnatal guinea-pig following intrauterine growth-restriction

scientific article published in September 2000

Regulation of Toll-like receptors in the choroid plexus in the immature brain after systemic inflammatory stimuli

scientific article published on 5 January 2013

Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia

scientific article published on 10 May 2011

Repeated episodes of umbilical cord occlusion in fetal sheep lead to preferential damage to the striatum and sensitize the heart to further insults.

scientific article published in June 1995

Role of cytokines in preterm labour and brain injury

scientific article published in March 2005

Role of mixed lineage kinase inhibition in neonatal hypoxia-ischemia

scientific article published on 11 August 2009

Safety aspects of longitudinal administration of IGF-I/IGFBP-3 complex in neonatal mice

scientific article published on 21 June 2011

Sex-Dependent Effects of Perinatal Inflammation on the Brain: Implication for Neuro-Psychiatric Disorders

scientific article published on 08 May 2019

Spirulina diet to lactating mothers protects the antioxidant system and reduces inflammation in post-natal brain after systemic inflammation

scientific article published on 29 August 2016

Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways

scientific article published on 15 April 2015

Suppression of postischemic epileptiform activity with MK-801 improves neural outcome in fetal sheep

scientific article published on November 1, 1992

Sustained Effects of Neonatal Systemic Lipopolysaccharide on IL-1β and Nrf2 in Adult Rat Substantia Nigra Are Partly Normalized by a Spirulina-Enriched Diet

scientific article published on 9 December 2016

Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of "pathological apoptosis"?

scientific article published on 21 December 2000

Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain

scientific article published on January 2017

Systemic stimulation of TLR2 impairs neonatal mouse brain development

scientific article published on 6 May 2011

TLR2-mediated leukocyte trafficking to the developing brain

scientific article published on 4 August 2016

Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury

scientific article published on 15 December 2016

The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK.

scientific article published on 23 February 2011

The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome

scientific article published on 26 November 2015

The effect of hypothalamic lesions on the length of gestation in fetal sheep

scientific article published in October 1991

The effect of osteopontin and osteopontin-derived peptides on preterm brain injury

scientific article published on 3 December 2014

The effects of IGF-1 treatment after hypoxic-ischemic brain injury in adult rats.

scientific article

The immune response after hypoxia-ischemia in a mouse model of preterm brain injury.

scientific article published on 5 September 2014

The myth of the immature barrier systems in the developing brain: role in perinatal brain injury

scientific article published in December 2018

The role of Toll-like receptors in perinatal brain injury

scientific article published on December 2009

The role of glucose in brain injury following the combination of lipopolysaccharide or lipoteichoic acid and hypoxia-ischemia in neonatal rats

scientific article published in January 2004

The role of inflammation in perinatal brain injury

scientific article published on 17 February 2015

Time-dependent effects of systemic lipopolysaccharide injection on regulators of antioxidant defence Nrf2 and PGC-1α in the neonatal rat brain

scientific article published in 2013

Toll-like receptor 3 expression in glia and neurons alters in response to white matter injury in preterm infants

scientific article published on 16 March 2013

Toll-like receptor-3 activation increases the vulnerability of the neonatal brain to hypoxia-ischemia

scientific article published on July 2013

Trace fear conditioning detects hypoxic-ischemic brain injury in neonatal mice

scientific article published on 21 July 2011

Transcriptomal changes and functional annotation of the developing non-human primate choroid plexus

scientific article published on 12 March 2015

Transient umbilical cord occlusion causes hippocampal damage in the fetal sheep.

scientific article published in November 1992

Translational Stroke Research: Vision and Opportunities

scientific article published on 27 July 2017

Vancomycin Is Protective in a Neonatal Mouse Model of Staphylococcus epidermidis-Potentiated Hypoxic-Ischemic Brain Injury

scientific article published on 21 February 2020

Vascular response to hypoxic preconditioning in the immature brain

scientific journal article

Ventriculomegaly and reduced hippocampal volume following intrauterine growth-restriction: implications for the aetiology of schizophrenia.

scientific article published in November 1999

Which neuroprotective agents are ready for bench to bedside translation in the newborn infant?

scientific article published on 9 February 2012

White matter damage after chronic subclinical inflammation in newborn mice

scientific article published on September 2009

White matter injury following prolonged free radical formation in the 0.65 gestation fetal sheep brain

scientific article published on 5 May 2005

White matter injury following systemic endotoxemia or asphyxia in the fetal sheep

scientific article published in February 2003

White matter injury in the immature brain: role of interleukin-18

scientific article published in December 2004

γδ T Cells Contribute to Injury in the Developing Brain

scientific article published on 14 December 2017

γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice

scientific article published on 20 December 2017