List of works - Alasdair Leslie

Adaptation of HIV-1 to human leukocyte antigen class I

scientific article published on 25 February 2009

Additive contribution of HLA class I alleles in the immune control of HIV-1 infection

scientific article published on 21 July 2010

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties

scientific article (publication date: 16 February 2010)

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study

scientific article published on 23 December 2015

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

scientific article published in 2024

Biological differences between the sexes and susceptibility to tuberculosis.

scientific article published in July 2014

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

scientific article published on 17 December 2006

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

scientific article published on 24 April 2015

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point

scientific article published on 2 July 2008

Compensatory Mutation Partially Restores Fitness and Delays Reversion of Escape Mutation within the Immunodominant HLA-B*5703-Restricted Gag Epitope in Chronic Human Immunodeficiency Virus Type 1 Infection

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection

scientific article

Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes

scientific article published on 24 January 2007

Correction for Thobakgale et al., Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

scientific article published on 8 July 2015

Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children

scholarly article by Maximilian Muenchhoff et al published 16 April 2019 in Journal of Infectious Diseases

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype

scientific article published in October 2006

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

scientific article published in December 2004

Evolution of HLA-B5703 HIV-1 escape mutations in HLA-B5703-positive individuals and their transmission recipients

scientific article published on 23 March 2009

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1

scientific article

HIV control through a single nucleotide on the HLA-B locus

scientific article published on 15 August 2012

HIV control through a single nucleotide on the HLA-I locus.

scientific article published on 13 September 2012

HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering

scholarly article by Philippa C Matthews et al published 15 April 2011 in Journal of Virology

HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering

scientific article published on 25 February 2009

HLA-A7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B5703

scientific article published on 15 April 2011

HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation

scientific article published on 25 August 2010

HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B57 that is distinct from HLA-B58:01

scientific article published on 17 July 2013

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

article

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

scientific article published on 01 May 2018

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

scientific article published on 6 May 2015

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

scientific article

Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection

scientific article published on 15 July 2009

Increased Regulatory T-Cell Activity and Enhanced T-Cell Homeostatic Signaling in Slow Progressing HIV-infected Children

article

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

scientific article published on February 2016

Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

scientific article published on 5 September 2015

Major TCR Repertoire Perturbation by Immunodominant HLA-B44:03-Restricted CMV-Specific T Cells

Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy

scientific article published on 2 July 2017

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

article

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

scientific article published in September 2016

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

scientific article (publication date: 21 September 2006)

Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus

scientific article published on 8 October 2015

Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

scientific article

Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection

scientific article published on 18 October 2006

RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events

scientific article

Role of HLA Adaptation in HIV Evolution

scientific article

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

scientific article published on 27 April 2020

Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling

scientific article published on 18 September 2017

Structure and Interactions of the Human Programmed Cell Death 1 Receptor

scientific article published on 26 April 2013

The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms

scientific article published on 24 November 2010

The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.

scientific article published in September 2013

Tissue-resident innate immunity in the lung

scientific article published on 21 November 2019

Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

scientific article published on 13 April 2021

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.

scientific article

Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition

scientific article published on 23 December 2020

List of works by Alasdair Leslie

Adaptation of HIV-1 to human leukocyte antigen class I

Additive contribution of HLA class I alleles in the immune control of HIV-1 infection

Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study

B cell heterogeneity in human tuberculosis highlights compartment-specific phenotype and functional roles

Biological differences between the sexes and susceptibility to tuberculosis.

CD8+ T-cell responses to different HIV proteins have discordant associations with viral load

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point

Compensatory Mutation Partially Restores Fitness and Delays Reversion of Escape Mutation within the Immunodominant HLA-B*5703-Restricted Gag Epitope in Chronic Human Immunodeficiency Virus Type 1 Infection

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection

Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes

Correction for Thobakgale et al., Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children

Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype

Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA.

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1

HIV control through a single nucleotide on the HLA-B locus

HIV control through a single nucleotide on the HLA-I locus.

HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering

HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering

HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703

HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation

HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

Human and Murine Clonal CD8+ T Cell Expansions Arise during Tuberculosis Because of TCR Selection

Immune selection for altered antigen processing leads to cytotoxic T lymphocyte escape in chronic HIV-1 infection

Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection

Increased Regulatory T-Cell Activity and Enhanced T-Cell Homeostatic Signaling in Slow Progressing HIV-infected Children

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

Major TCR Repertoire Perturbation by Immunodominant HLA-B44:03-Restricted CMV-Specific T Cells

Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Pattern recognition receptor mediated downregulation of microRNA-650 fine-tunes MxA expression in dendritic cells infected with influenza A virus

Programmed death-1 expression on HIV-1-specific CD8+ T cells is shaped by epitope specificity, T-cell receptor clonotype usage and antigen load

Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection

RNA and imidazoquinolines are sensed by distinct TLR7/8 ectodomain sites resulting in functionally disparate signaling events

Role of HLA Adaptation in HIV Evolution

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

Snapin promotes HIV-1 transmission from dendritic cells by dampening TLR8 signaling

Structure and Interactions of the Human Programmed Cell Death 1 Receptor

The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms

The intracellular sensor NOD2 induces microRNA-29 expression in human dendritic cells to limit IL-23 release.

Tissue-resident innate immunity in the lung

Tissue-resident-like CD4+ T cells secreting IL-17 control Mycobacterium tuberculosis in the human lung

Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA.

Vaginal microbiome-hormonal contraceptive interactions associate with the mucosal proteome and HIV acquisition

Evolution of HLA-B5703 HIV-1 escape mutations in HLA-B5703-positive individuals and their transmission recipients

HLA-A7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B5703

HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B57 that is distinct from HLA-B58:01