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List of works by Akira Horii

A Novel SDHB IVS2-2A>C Mutation Is Responsible for Hereditary Pheochromocytoma/Paraganglioma Syndrome

scientific article published on 01 June 2018

A cDNA microarray analysis identifies 52 genes associated with cis-diamminedichloroplatinum susceptibility in head and neck squamous cell carcinoma cell lines.

scientific article

A new 10-min ligation method using a modified buffer system with a very low amount of T4 DNA ligase: the "Coffee Break Ligation" technique

scientific article published on 21 June 2007

A new assay using surface plasmon resonance (SPR) to determine binding of the Lactobacillus acidophilus group to human colonic mucin.

scientific article

A novel G106D alteration of the SDHD gene in a pedigree with familial paraganglioma

scientific article published on 01 November 2006

A novel target gene, SKP2, within the 5p13 amplicon that is frequently detected in small cell lung cancers.

scientific article published on July 2002

A novel type of human alpha-amylase produced in lung carcinoid tumor.

scientific article

ABCB1 Is Upregulated in Acquisition of Taxane Resistance: Lessons from Esophageal Squamous Cell Carcinoma Cell Lines.

scientific article published on January 2016

APAF-1-ALT, a novel alternative splicing form of APAF-1, potentially causes impeded ability of undergoing DNA damage-induced apoptosis in the LNCaP human prostate cancer cell line.

scientific article published on June 2003

Abrogation of DUSP6 by hypermethylation in human pancreatic cancer

scientific article (publication date: 2005)

Acquisition of chemoresistance to gemcitabine is induced by a loss-of-function missense mutation of DCK.

scientific article published on 18 July 2015

Adrenocortical tumor in a patient with familial adenomatous polyposis: a case associated with a complete inactivating mutation of the APC gene and unusual histological features.

scientific article

Allelic loss of the NF1 gene in anal malignant melanoma in a patient with neurofibromatosis type 1

scientific article published on 01 August 2001

Alternative splicing of GTBP in normal human tissues

scientific article

An adhesin-like protein, Lam29, from Lactobacillus mucosae ME-340 binds to histone H3 and blood group antigens in human colonic mucus.

scientific article

Analysis of the p53 gene mutations in patients with multiple primary cancers of the oesophagus

scientific article published on 01 August 1997

Atrial natriuretic peptide induces peroxisome proliferator activated receptor γ during cardiac ischemia-reperfusion in swine heart.

scientific article

BRAF point mutations in primary melanoma show different prevalences by subtype.

scientific article published on July 2004

CD45+CD326+ Cells are Predictive of Poor Prognosis in Non-Small Cell Lung Cancer Patients

scientific article published on 05 August 2019

Cancer-associated splicing variants of the CDCA1 and MSMB genes expressed in cancer cell lines and surgically resected gastric cancer tissues.

scientific article

Cell surface glyceraldehyde-3-phosphate dehydrogenase (GAPDH) of Lactobacillus plantarum LA 318 recognizes human A and B blood group antigens.

scientific article

Characteristic clinicopathological features of the types of intraductal papillary-mucinous neoplasms of the pancreas.

scientific article published in November 2007

Characterization of functional transient receptor potential melastatin 8 channels in human pancreatic ductal adenocarcinoma cells

scientific article published on July 2014

Chromosome 12, frequently deleted in human pancreatic cancer, may encode a tumor-suppressor gene that suppresses angiogenesis.

scientific article published on October 2004

Clinicopathological study of SDHB mutation-related pheochromocytoma and sympathetic paraganglioma

scientific article published on 6 May 2014

Cloning and characterization of a third type of human alpha-amylase gene, AMY2B

scientific article

Cloning and characterization of the human UDP-N-acetylglucosamine: alpha-1,3-D-mannoside beta-1,4-N-acetylglucosaminyltransferase IV-homologue (hGnT-IV-H) gene.

scientific article published on January 1999

Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes

scientific journal article

Comparative genomic hybridization and mutation analyses of sporadic schwannomas.

scientific article

Computed tomographic images reflect the biologic behavior of small lung adenocarcinoma: they correlate with cell proliferation, microvascularization, cell adhesion, degradation of extracellular matrix, and K-ras mutation.

scientific article published in September 2005

DCK is frequently inactivated in acquired gemcitabine-resistant human cancer cells.

scientific article

DNA Methylation in Cancer: A Gene Silencing Mechanism and the Clinical Potential of Its Biomarkers ⬇️

scientific article published on March 1, 2013

Deletion mapping of 14q32 in human neuroblastoma defines an 1,100-kb region of common allelic loss

scientific article published on 01 December 2000

Double cancer in a 74-year-old woman: a case report with genetic findings

scientific article published on 01 April 1996

Epigenetic inactivation of IRX4 is responsible for acceleration of cell growth in human pancreatic cancer

scientific article published on 07 September 2020

Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal tumorigenesis.

scientific article published in July 2001

Expression of SNAIL in accompanying PanIN is a key prognostic indicator in pancreatic ductal adenocarcinomas

scientific article published on 21 February 2019

Expression of pancreatic secretory trypsin inhibitor gene in human colorectal tumor

scientific article published on 01 November 1990

Expression of pancreatic secretory trypsin inhibitor gene in neoplastic tissues

scientific article

Feedback regulation of DUSP6 transcription responding to MAPK1 via ETS2 in human cells.

scientific article published on 9 October 2008

Frameshift mutation at codon 642 of the hMLH1 gene in human endometrial cancer

scientific article published on 01 January 1996

Frequent Loss of Heterozygosity at the MCC Locus on Chromosome 5q21-22 in Sporadic Colorectal Carcinomas ⬇️

scientific article published on September 1, 1991

Frequent deletions of material from chromosome arm 1p in oligodendroglial tumors revealed by double-target fluorescence in situ hybridization and microsatellite analysis.

scientific article published in December 1995

Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma

scientific article published on 01 July 1997

Frequent gains on chromosome arms 1q and/or 8q in human endometrial cancer

scientific article published on 01 October 1997

Gene Therapy for Pancreatic Cancer Targeting the Genomic Alterations of Tumor Suppressor Genes using Replication-selective Oncolytic Adenovirus

scientific article published on September 1, 2002

Genetic and epigenetic aberrations of ABCB1 synergistically boost the acquisition of taxane resistance in esophageal squamous cancer cells

scientific article published on 01 April 2020

Genome-wide profiling of promoter methylation in human

scientific article published on 01 May 2006

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients ⬇️

scientific article published on May 15, 1992

Homozygous deletion in a neuroblastoma cell line defined by a high-density STS map spanning human chromosome band 1p36.

scientific article

Human BAC Contig Covering the Deleted Region in Pancreatic Cancer at 12q21 ⬇️

scientific article published on January 1, 2001

Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization.

scientific article

Identification of a 100-kb region of common allelic loss on chromosome bands 10q25-q26 in human endometrial cancer

scientific article published on 01 September 1998

Identification of a 700-kb region of common allelic loss in chromosome bands 3p14.3-p21.1 in human renal cell carcinoma

scientific article published on 01 July 1998

Identification of a 910-kb region of common allelic loss in chromosome bands 16q24.1-q24.2 in human lung cancer

scientific article published on 01 May 1998

Identification of a new adhesin-like protein from Lactobacillus mucosae ME-340 with specific affinity to the human blood group A and B antigens.

scientific article published in September 2010

Identification of a novel alpha-amylase by expression of a newly cloned human amy3 cDNA in yeast

scientific article published on 01 May 1990

Identification of epigenetically silenced genes in human pancreatic cancer by a novel method “microarray coupled with methyl-CpG targeted transcriptional activation” (MeTA-array) ⬇️

scientific article published on June 23, 2011

Identification of the homozygously deleted region at chromosome 1p36.2 in human neuroblastoma

scientific article published on 01 December 2000

Immune responses to DNA mismatch repair enzymes hMSH2 and hPMS1 in patients with pancreatic cancer, dermatomyositis and polymyositis

scientific article (publication date: 10 October 2005)

In vivo induction of necrosis in mice fibrosarcoma via intravenous injection of type B staphylococcal enterotoxin

scientific article published on 24 July 2008

Infrequent Genetic Alterations of the PTEN/MMAC1 Gene in Japanese Patients with Primary Cancers of the Breast, Lung, Pancreas, Kidney, and Ovary ⬇️

scientific article published on November 1, 1997

Infrequent genetic alterations of the PTEN gene in Japanese patients with sporadic prostate cancer

scientific article published on 01 January 1998

Infrequent mutation of APC, AXIN1, and GSK3B in human pituitary adenomas with abnormal accumulation of CTNNB1.

scientific article

Infrequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers of the esophagus and various other tissues.

scientific article

Isolation and characterization of the human gene homologous to the Drosophila headcase (hdc) gene in chromosome bands 6q23-q24, a region of common deletion in human pancreatic cancer

scientific article

Lactic Acid Bacteria (LAB) Bind to Human B- or H-Antigens Expressed on Intestinal Mucosa

scientific article published on 07 December 2006

Lactobacilli binding human A-antigen expressed in intestinal mucosa

scientific article published on 30 March 2006

Life and mental health of medical students after the Great East Japan Earthquake.

scientific article published on January 2015

Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers

scientific article published on 26 February 2014

Loss of heterozygosity analyses of asynchronous lesions of ductal carcinoma in situ and invasive ductal carcinoma of the human breast

scientific article published on 01 November 2003

Lymph node resection induces the activation of tumor cells in the lungs

scientific article published on 17 January 2019

Methyl-CpG targeted recruitment of p300 reactivates tumor suppressor genes in human cancer cells.

scientific article

Methyl-CpG targeted transcriptional activation allows re-expression of tumor suppressor genes in human cancer cells.

scientific article

Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance ⬇️

scientific article published on April 15, 2012

Methylation-mediated silencing of the LIM homeobox 6 (LHX6) gene promotes cell proliferation in human pancreatic cancer

scientific article published on 02 April 2020

Microarray analysis of promoter methylation in lung cancers.

scientific article published on 25 January 2006

Microarray coupled with methyl-CpG targeted transcriptional activation (MeTA-array) identifies hypermethylated genes containing the stringent criteria of CpG islands at high frequency ⬇️

scientific article published on June 1, 2011

Molecular cloning and expression of cDNA encoding chicken UDP-N-acetyl-D-glucosamine (GlcNAc): GlcNAcbeta 1-6(GlcNAcbeta 1-2)- manalpha 1-R[GlcNAc to man]beta 1,4N-acetylglucosaminyltransferase VI.

scientific article

Molecular events in human T cells treated with diesel exhaust particles or formaldehyde that underlie their diminished interferon-gamma and interleukin-10 production.

scientific article

Molecular mechanisms of pancreatic carcinogenesis.

scientific article

Molecular pathology of pancreatic cancer

scientific article published on 01 January 2014

Multiple forms of the APC gene transcripts and their tissue-specific expression.

scientific article published in March 1993

Multiple functions of S100A10, an important cancer promoter

scientific article published on 14 October 2019

Mutations in the serine protease inhibitor Kazal Type 1 (SPINK1) gene in Japanese patients with pancreatitis

scientific article published on 23 June 2005

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

scientific article

Mutations of the APC (adenomatous polyposis coli) gene in FAP (familial polyposis coli) patients and in sporadic colorectal tumors

scientific article published on 01 October 1992

NDRG2, suppressed expression associates with poor prognosis in pancreatic cancer, is hypermethylated in the second promoter in human gastrointestinal cancers.

scientific article published on 13 January 2017

New screening methods for probiotics with adhesion properties to sialic acid and sulphate residues in human colonic mucin using the Biacore assay.

scientific article published on 7 January 2013

Orthotopic implantation mouse model and cDNA microarray analysis indicates several genes potentially involved in lymph node metastasis of colorectal cancer.

scientific article published on 27 February 2008

PTEN1 is frequently mutated in primary endometrial carcinomas

scientific article (publication date: October 1997)

Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer

scientific article

Potential utility of eGFP-expressing NOG mice (NOG-EGFP) as a high purity cancer sampling system ⬇️

scientific article published on June 6, 2012

Primary structure of human pancreatic alpha-amylase gene: its comparison with human salivary alpha-amylase gene

scientific article

Primary structure of human pancreatic secretory trypsin inhibitor (PSTI) gene

scientific article

Production of salivary type alpha-amylase in human lung cancer

scientific article published on 01 April 1989

Promoter hypermethylation is not the major mechanism for inactivation of the FBXW7 beta-form in human gliomas.

scientific article published on August 2008

Proposal of screening method for intestinal mucus adhesive lactobacilli using the enzymatic activity of glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

article

Quantitative evaluation of adhesion of lactobacilli isolated from human intestinal tissues to human colonic mucin using surface plasmon resonance (BIACORE assay).

scientific article published in January 2007

RET finger protein enhances MBD2- and MBD4-dependent transcriptional repression.

scientific article

RNA interference targeting aurora kinase a suppresses tumor growth and enhances the taxane chemosensitivity in human pancreatic cancer cells.

scientific article

Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells.

scientific article published in October 2003

Road to early detection of pancreatic cancer: Attempts to utilize epigenetic biomarkers ⬇️

scientific article published on March 23, 2012

S100A10 upregulation associates with poor prognosis in lung squamous cell carcinoma

scientific article published on 27 September 2018

S100A4 is frequently overexpressed in lung cancer cells and promotes cell growth and cell motility.

scientific article published on 13 April 2014

S100A4, frequently overexpressed in various human cancers, accelerates cell motility in pancreatic cancer cells.

scientific article

Saponin Facilitates Anti-Robo1 Immunotoxin Cytotoxic Effects on Maxillary Sinus Squamous Cell Carcinoma

scientific article published on 11 March 2020

Single-dose rosuvastatin ameliorates lung ischemia-reperfusion injury via upregulation of endothelial nitric oxide synthase and inhibition of macrophage infiltration in rats with pulmonary hypertension

scientific article published on 15 October 2014

Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma

scientific article (publication date: November 1992)

Somatic mutations of a human mismatch repair gene, hMLH1, in tumors from patients with multiple primary cancers

scientific article published on 01 January 1996

Suppressed expression of NDRG2 correlates with poor prognosis in pancreatic cancer

scientific article published on 14 October 2013

Suppression of the tumorigenic phenotype by chromosome 18 transfer into pancreatic cancer cell lines

scientific article published on 01 June 2002

Synchronous and metachronous extrapancreatic malignant neoplasms in patients with intraductal papillary-mucinous neoplasm of the pancreas

scientific article published on 29 September 2008

Targeted TET oxidase activity through methyl-CpG-binding domain extensively suppresses cancer cell proliferation.

scientific article published on 25 July 2016

Technological advances in epigenomics lead to a better understanding of inflammatory diseases, decitabine and H3K27me3

scientific article published on 01 January 2015

The PMAIP1 gene on chromosome 18 is a candidate tumor suppressor gene in human pancreatic cancer.

scientific article published on 31 January 2008

The PTEN, BAX, and IGFIIR genes are mutated in endometrial atypical hyperplasia.

scientific article published in October 1998

The expression of S100A4 in human pancreatic cancer is associated with invasion.

scientific article published on August 2013

The methylation status of FBXW7 beta-form correlates with histological subtype in human thymoma.

scientific article published on 18 October 2008

The role of chromosome 18 abnormalities in the progression of pancreatic adenocarcinoma.

scientific article published in April 2004

The thymine DNA glycosylase MBD4 represses transcription and is associated with methylated p16(INK4a) and hMLH1 genes

scientific article

Transcription of human endogenous retroviral long terminal repeat (LTR) sequence in a lung cancer cell line.

scientific article

Transcriptional silencing of ETS-1 efficiently suppresses angiogenesis of pancreatic cancer.

scientific article published on 5 September 2008

Treatment with Lactobacillus Retards the Tumor Growth of Head and Neck Squamous Cell Carcinoma Cells Inoculated in Mice

scientific article published on 01 August 2018

Upregulation of IGF2 is associated with an acquired resistance for cis-diamminedichloroplatinum in human head and neck squamous cell carcinoma.

scientific article

miR-34a is downregulated in cis-diamminedichloroplatinum treated sinonasal squamous cell carcinoma patients with poor prognosis.

scientific article published on 6 July 2012

p190A RhoGAP is involved in EGFR pathways and promotes proliferation, invasion and migration in lung adenocarcinoma cells

scientific article published on 13 September 2013

p24/ING1-ALT1 and p47/ING1-ALT2, distinct alternative transcripts of p33/ING1

scientific article (publication date: 2000)

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