List of works - Laura E McCoy

A gp41 MPER-specific Llama VHH Requires a Hydrophobic CDR3 for Neutralization but not for Antigen Recognition

scientific article

A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 determinant for neutralization but not for antigen recognition.

scientific article published on 13 September 2012

Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes

scientific article published on 30 September 2019

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

scientific article published on 17 March 2020

Broad and potent neutralization of HIV-1 by human-llama fusion antibodies derived from immunized llamas

article

Circulating and intrahepatic antiviral B cells are defective in hepatitis B

scientific article published on 09 August 2018

Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings

scientific article published on 24 September 2020

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

article

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.

scientific article published on 28 January 2018

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

scientific article

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

scientific article published on 07 September 2016

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

scientific article published on 05 June 2020

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

scientific article published on 17 August 2016

Identification and specificity of broadly neutralizing antibodies against HIV

scientific article published on January 2017

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

scientific article published on November 2015

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

scientific article published on 12 August 2015

Lessons learned from humoral responses of HIV patients.

scientific article

Mapping the IkappaB kinase beta (IKKbeta)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKbeta-mediated activation of nuclear factor kappaB.

scientific article published on 7 April 2011

Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1

scientific article

Mutations in modified virus Ankara protein 183 render it a non-functional counterpart of B14, an inhibitor of nuclear factor kappaB activation.

scientific article

Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.

scientific article published on 2 October 2014

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

scientific article published on 21 April 2015

Neutralizing antibodies to HIV-1 induced by immunization.

scientific article published on February 2013

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

scientific article published on 06 November 2020

Report from the First EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children's Actual Life with Novel Immunotherapeutic Strategies) General Assembly meeting, 9-11 November 2017, Rome, Italy.

scientific article published in January 2018

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.

scientific article

The expanding array of HIV broadly neutralizing antibodies

article

Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights

scientific article

List of works by Laura E McCoy

A gp41 MPER-specific Llama VHH Requires a Hydrophobic CDR3 for Neutralization but not for Antigen Recognition

A gp41 MPER-specific llama VHH requires a hydrophobic CDR3 determinant for neutralization but not for antigen recognition.

Antibody Responses Elicited by Immunization with BG505 Trimer Immune Complexes

Autologous Antibody Responses to an HIV Envelope Glycan Hole Are Not Easily Broadened in Rabbits

Broad and potent neutralization of HIV-1 by human-llama fusion antibodies derived from immunized llamas

Circulating and intrahepatic antiviral B cells are defective in hepatitis B

Comparative assessment of multiple COVID-19 serological technologies supports continued evaluation of point-of-care lateral flow assays in hospital and community healthcare settings

Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization

Elicitation of Neutralizing Antibodies Targeting the V2 Apex of the HIV Envelope Trimer in a Wild-Type Animal Model.

Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches

HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

Identification and specificity of broadly neutralizing antibodies against HIV

Identification of Common Features in Prototype Broadly Neutralizing Antibodies to HIV Envelope V2 Apex to Facilitate Vaccine Design

Incomplete Neutralization and Deviation from Sigmoidal Neutralization Curves for HIV Broadly Neutralizing Monoclonal Antibodies

Lessons learned from humoral responses of HIV patients.

Mapping the IkappaB kinase beta (IKKbeta)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKbeta-mediated activation of nuclear factor kappaB.

Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1

Mutations in modified virus Ankara protein 183 render it a non-functional counterpart of B14, an inhibitor of nuclear factor kappaB activation.

Neutralisation of HIV-1 cell-cell spread by human and llama antibodies.

Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas

Neutralizing antibodies to HIV-1 induced by immunization.

Preexisting and de novo humoral immunity to SARS-CoV-2 in humans

Report from the First EPIICAL (Early-treated Perinatally HIV-infected Individuals: Improving Children's Actual Life with Novel Immunotherapeutic Strategies) General Assembly meeting, 9-11 November 2017, Rome, Italy.

Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.

The expanding array of HIV broadly neutralizing antibodies

Unravelling the Molecular Basis of High Affinity Nanobodies against HIV p24: In Vitro Functional, Structural, and in Silico Insights