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List of works by Panu M Jaakkola

Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2

scientific article published on 01 December 2000

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

scientific article

Different mechanisms of syndecan-1 activation through a fibroblast-growth-factor-inducible response element (FiRE) in mucosal and cutaneous wounds.

scientific article published in May 2003

Expression of the cellular oxygen sensor PHD2 (EGLN-1) predicts radiation sensitivity in squamous cell cancer of the head and neck.

scientific article published in January 2009

Functional characterization of mouse syndecan-1 promoter.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma

scientific article published on 04 July 2017

Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27.

scientific article published on 30 July 2015

Hypoxia-activated Smad3-specific dephosphorylation by PP2A.

scientific article

Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62

scientific article published on 20 October 2008

Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma

scientific article published on 07 January 2019

Hypoxia-inducible factor-1 (HIF-1) promotes its degradation by induction of HIF-alpha-prolyl-4-hydroxylases.

scientific article published on August 2004

Hypoxic conversion of SMAD7 function from an inhibitor into a promoter of cell invasion

scientific article published on 15 June 2010

Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling.

scientific article published on 3 February 2012

Intra- and extracellular signaling by endothelial neuregulin-1

scientific article published on 18 April 2007

Overall Survival and Metastasis Resections in Patients with Metastatic Colorectal Cancer Using Electronic Medical Records

scientific article

Overexpression and nuclear translocation of hypoxia-inducible factor prolyl hydroxylase PHD2 in head and neck squamous cell carcinoma is associated with tumor aggressiveness.

scientific article published on February 2006

Preoperative radiotherapy downregulates the nuclear expression of hypoxia-inducible factor-1alpha in rectal cancer

scientific article published on 01 March 2010

Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells.

scientific article

Pronounced tumour regression after radiotherapy is associated with negative/weak glucose transporter-1 expression in rectal cancer

scientific article published on 01 January 2011

Proximal promoter of the murine syndecan-1 gene is not sufficient for the developmental pattern of syndecan expression in B lineage cells.

scientific article published on May 2001

Proximal promoter-independent activation of the far-upstream FGF-inducible response element of syndecan-1 gene.

scientific article published on November 2000

ROTS: reproducible RNA-seq biomarker detector-prognostic markers for clear cell renal cell cancer

scientific article published on 11 August 2015

Reply: expression of carbonic anhydrase IX suggests poor response to therapy in rectal cancer.

scientific article published on 30 June 2009

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

scientific article

The activation and composition of FiRE (an FGF-inducible response element) differ in a cell type- and growth factor-specific manner.

scientific article published on September 1998

The regulation, localization, and functions of oxygen-sensing prolyl hydroxylase PHD3.

scientific article published on April 2013

The role of HIF prolyl hydroxylases in tumour growth.

scientific article published on 22 February 2010

Transcriptional regulation of Syndecan-1 expression by growth factors

scientific article (publication date: 1999)

Transportable system enabling multiple irradiation studies under simultaneous hypoxia in vitro

Uptake of [(18)F]EF5 as a Tracer for Hypoxic and Aggressive Phenotype in Experimental Head and Neck Squamous Cell Carcinoma.

scientific article published on 23 May 2014

[Tumor hypoxia:advantage or disadvantage?]

scientific article published on 01 January 2005

p62 degradation by autophagy: another way for cancer cells to survive under hypoxia.

scientific article published on 16 April 2009

p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation.

scientific article published on 23 January 2013

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