List of works by Roger A. Barker

"The eyes have it". Saccadometry and Parkinson's disease

scientific article

'The clocks that time us'--circadian rhythms in neurodegenerative disorders

scientific article

11 C-PE2I and 18 F-Dopa PET for assessing progression rate in Parkinson's: A longitudinal study.

scientific article published on 30 October 2017

A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease

scientific article published on 28 June 2016

A blueprint for translational regenerative medicine

scientific article published on 01 December 2020

A case of late onset sporadic Parkinson's disease with an A53T mutation in alpha-synuclein.

scientific article published in April 2005

A case of unilateral neglect in Huntington's disease

scientific article published in June 2003

A cell atlas of human thymic development defines T cell repertoire formation

scientific article published on 01 February 2020

A comparative study of preparation techniques for improving the viability of nigral grafts using vital stains, in vitro cultures, and in vivo grafts

scientific article published on 01 March 1995

A genome wide linkage disequilibrium screen in Parkinson’s disease

scientific article published on 23 February 2005

A multicentre study on grey matter morphometric biomarkers for classifying early schizophrenia and parkinson’s disease psychosis

scientific article published in 2023

A new approach to disease-modifying drug trials in Parkinson's disease

scientific article published on June 2013

A non-cell autonomous mouse model of CNS haemangioblastoma mediated by mutant KRAS

scientific article published on 21 March 2017

A novel combinational approach of microstimulation and bioluminescence imaging to study the mechanisms of action of cerebral electrical stimulation in mice

scientific article published on 24 March 2015

A novel neuroprotective therapy for Parkinson's disease using a viral noncoding RNA that protects mitochondrial complex I activity

scientific article

A pathophysiological model of freezing of gait in Parkinson's disease

scientific article

A retrospective analysis of hand tapping as a longitudinal marker of disease progression in Huntington's disease

scientific article

A role for complement in the rejection of porcine ventral mesencephalic xenografts in a rat model of Parkinson's disease.

scientific article

A simple assessment model to quantifying the dynamic hippocampal neurogenic process in the adult mammalian brain.

scientific article published on 7 October 2015

Aberrant nigral diffusion in Parkinson's disease: A longitudinal diffusion tensor imaging study

scientific article published on 22 April 2016

Abnormalities of age-related T cell senescence in Parkinson's disease.

scientific article

Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment.

scientific article published on December 2005

Addenbrooke's Cognitive Examination-Revised for mild cognitive impairment in Parkinson's disease.

scientific article published on 25 June 2012

Adult neurogenesis is unaffected by a functional knock-out of MHC class I in mice

scientific article published in March 2010

Advancing pharmacotherapy for treating Huntington's disease: a review of the existing literature

scientific article

Alpha Gal is widely expressed in embryonic porcine stem cells and neural tissue.

scientific article

An open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington's disease

scientific article published on 26 October 2017

Animal models of neurodegenerative diseases.

scientific article published in January 2009

Anti-amyloid compounds inhibit α-synuclein aggregation induced by protein misfolding cyclic amplification (PMCA)

scientific article published on 28 February 2014

Anticholinergic Load: Is there a Cognitive Cost in Early Parkinson's Disease?

scientific article published on 3 October 2015

Antidopaminergic Medication is Associated with More Rapidly Progressive Huntington's Disease

scientific article published in July 2015

Anxiety is associated with cognitive impairment in newly-diagnosed Parkinson's disease

scientific article published on 04 January 2017

Apolipoprotein E genotype as a risk factor for susceptibility to and dementia in Parkinson's disease

scientific article published on 18 March 2009

Are Stem Cell-Based Therapies for Parkinson's Disease Ready for the Clinic in 2016?

scientific article

Are trials of intravascular infusions of autologous mesenchymal stem cells in patients with multiple system atrophy currently justified, and are they effective?

scientific article published on 01 May 2008

Assessment of the Performance of a Modified Motor Scale as Applied to Juvenile Onset Huntington's Disease

scientific article published on 01 January 2019

Association between MAPT haplotype and memory function in patients with Parkinson's disease and healthy aging individuals

scientific article

Association of the human leucocyte antigen region with susceptibility to Parkinson's disease

scientific article published on 12 May 2010

Associations between Lifestyle Factors and Parkinson's Disease in an Urban Sri Lankan Clinic Study.

scientific article published in September 2017

Asymptomatic sleep abnormalities are a common early feature in patients with Huntington's disease

scientific article published in April 2011

Atomoxetine restores the response inhibition network in Parkinson's disease

scientific article published on 24 June 2016

Attentional control in Parkinson's disease is dependent on COMT val 158 met genotype

scientific article published on 4 January 2008

Author Correction: Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease.

scientific article published on 24 May 2018

Automated quantification of caudate atrophy by local registration of serial MRI: evaluation and application in Huntington's disease.

scientific article published on 10 June 2009

Autonomic Dysfunction in Early Parkinson's Disease: Results from the United Kingdom Tracking Parkinson's Study

scholarly article

BDNF val66met influences time to onset of levodopa induced dyskinesia in Parkinson's disease.

scientific article published on 31 October 2008

Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study.

scientific article

Biomarkers in Huntington's and Parkinson's Disease

scientific article published in October 2009

Body composition in premanifest Huntington's disease reveals lower bone density compared to controls

scientific article

CD24 expression does not affect dopamine neuronal survival in a mouse model of Parkinson's disease

scientific article

Can endogenous stem cells be stimulated to repair the degenerating brain?

scientific article published in October 2004

Catechol O-methyltransferase Val158Met genotype influences frontoparietal activity during planning in patients with Parkinson's disease

scientific article

Categorising Visual Hallucinations in Early Parkinson's Disease

scientific article published on 01 January 2018

Cell replacement therapy for Parkinson's disease

scientific article published on 25 October 2008

Cell therapies and Parkinson's disease: where next? Interviewed by Emily Culme-Seymour

scientific article published on November 2010

Cell therapies for Parkinson's disease: how far have we come?

scientific article published on 25 November 2016

Cell therapies for neurological disease--from bench to clinic to bench

article published in 2005

Cell therapy in Huntington disease

scientific article

Cell-based therapies for Parkinson disease—past insights and future potential

scientific article published on 4 August 2015

Cell-based therapies for Parkinson's disease

scientific article published on June 2011

Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study.

scientific article

Cerebrovascular and blood-brain barrier impairments in Huntington's disease: Potential implications for its pathophysiology

scientific article

Challenges assessing clinical endpoints in early Huntington disease

scientific article

Characterization and Visualization of Vesicles in the Endo-Lysosomal Pathway with Surface-Enhanced Raman Spectroscopy and Chemometrics

scientific article published on 9 December 2015

Characterizing mild cognitive impairment in incident Parkinson disease: the ICICLE-PD study

scientific article published on 20 December 2013

Clinical and genetic characteristics of late-onset Huntington's disease

scientific article

Clinical translation of stem cells in neurodegenerative disorders.

scientific article

Clusterin secreted by astrocytes enhances neuronal differentiation from human neural precursor cells.

scientific article

Cognitive decline and quality of life in incident Parkinson's disease: The role of attention

scientific article published on 11 April 2016

Cognitive deficits and psychosis in Parkinson's disease: a review of pathophysiology and therapeutic options

scientific article

Cognitive follow up of a small cohort of Huntington's disease patients over a 5 year period

scientific article

Cognitive impairment in Parkinson's disease: the dual syndrome hypothesis

scientific article published on 03 October 2012

Cognitive impairments in early Parkinson's disease are accompanied by reductions in activity in frontostriatal neural circuitry.

scientific article published in July 2003

Comparative epidemiology of incident Parkinson's disease in Cambridgeshire, UK.

scientific article

Comprehensive cell atlas of the first-trimester developing human brain

scientific article published on 12 October 2023

Continuing trials of GDNF in Parkinson's disease

scientific article

Coping processes and health-related quality of life in Parkinson's disease.

scientific article published on 13 July 2010

Cortical and Striatal Reward Processing in Parkinson's Disease Psychosis

scientific article

Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers

scientific article published on 22 October 2009

Current Pharmacological Management in Juvenile Huntington's Disease.

scientific article

Current status of clinical trials of neural transplantation in Parkinson's disease

scientific article published on January 2012

Current understanding of the glial response to disorders of the aging CNS.

scientific article published on 28 May 2012

Decreased hippocampal cell proliferation in R6/1 Huntington's mice.

scientific article published in April 2004

Deep brain stimulation: eye movements reveal anomalous effects of electrode placement and stimulation

scientific article

Defective Sphingosine-1-phosphate metabolism is a druggable target in Huntington's disease

scientific article

Defective emotion recognition in early HD is neuropsychologically and anatomically generic.

scientific article published on 6 March 2008

Defining meaningful outcome measures in trials of disease-modifying therapies in Parkinson's disease

scientific article published on 23 February 2011

Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data

scientific article

Dermal fibroblasts from patients with Parkinson's disease have normal GCase activity and autophagy compared to patients with PD and GBA mutations

scientific article published on 26 September 2017

Determinants of delayed diagnosis in Parkinson's disease

scientific article published on 10 April 2013

Developing and validating Parkinson's disease subtypes and their motor and cognitive progression

scientific article published on 25 July 2018

Developing stem cell therapies for Parkinson's disease: waiting until the time is right

scientific article published on 6 November 2014

Development and external validation of a prognostic model in newly diagnosed Parkinson disease

scientific article published on 17 February 2016

Developmentally coordinated extrinsic signals drive human pluripotent stem cell differentiation toward authentic DARPP-32+ medium-sized spiny neurons

scientific article published in January 2013

Diagnostic criteria for mild cognitive impairment in Parkinson's disease: Movement Disorder Society Task Force guidelines

scientific article published on 24 January 2012

Diagnostic potential of saccadometry in progressive supranuclear palsy

scientific article published on 01 December 2007

Different decision deficits impair response inhibition in progressive supranuclear palsy and Parkinson's disease

scientific article

Direct Neuronal Reprogramming for Disease Modeling Studies Using Patient-Derived Neurons: What Have We Learned?

scientific article published on 28 September 2017

Disintegration of the sleep-wake cycle and circadian timing in Huntington's disease.

scientific article published in January 2005

Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.

scientific article

Dopamine and Huntington's disease.

scientific article published on 16 March 2015

Dopamine stimulates epidermal growth factor release from adult neural precursor cells derived from the subventricular zone by a disintegrin and metalloprotease

scientific article published in December 2011

Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF.

scholarly article

Dopaminergic basis for deficits in working memory but not attentional set-shifting in Parkinson's disease

scientific article

Dopaminergic modulation of high-level cognition in Parkinson's disease: the role of the prefrontal cortex revealed by PET.

scientific article published in March 2002

Dopaminergic modulation of neurogenesis in the subventricular zone of the adult brain

scientific article published on 14 September 2009

Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon

scientific article published on 01 January 1995

Dura mater-associated Creutzfeldt-Jakob disease: experience from surveillance in the UK.

scientific article

Dynamic and Cell-Specific DACH1 Expression in Human Neocortical and Striatal Development.

scientific article published on 24 April 2018

Dynamic causal modelling of effective connectivity from fMRI: are results reproducible and sensitive to Parkinson's disease and its treatment?

scientific article published on 4 January 2010

Efficient expansion and dopaminergic differentiation of human fetal ventral midbrain neural stem cells by midbrain morphogens

scientific article

Emerging Treatment Approaches for Parkinson's Disease

scholarly article by Thomas B Stoker et al published 2018 in Frontiers in Neuroscience

Emerging drug therapies in Huntington's disease

scientific article published on June 2009

Equating scores of the University of Pennsylvania Smell Identification Test and Sniffin' Sticks test in patients with Parkinson's disease

scientific article

Erratum. Correction to: Dopamine and Huntington's disease

scientific article published on 2 November 2015

Erratum: Author Correction: Using a smartphone-based self-management platform to support medication adherence and clinical consultation in Parkinson's disease

scientific article published on 13 November 2017

Evolution of cognitive dysfunction in an incident Parkinson's disease cohort.

scientific article published on 29 May 2007

Excessive daytime sleepiness and its risk factors in incident Parkinson's disease

scientific article published on 26 November 2012

Exogenous melatonin for Parkinson's disease: 'Waking up' to the need for further trials

scientific article published on 13 May 2016

Exogenous neuropeptide Y promotes in vivo hippocampal neurogenesis.

scientific article

FAMILY HISTORY IN YOUNG ONSET PARKINSON'S DISEASE

scholarly article by Naveed Malek et al published 9 October 2013 in Journal of Neurology, Neurosurgery and Psychiatry

Features of GBA-associated Parkinson's disease at presentation in the UK Tracking Parkinson's study

scientific article published on 29 January 2018

Fetal dopaminergic transplantation trials and the future of neural grafting in Parkinson's disease

scientific article published on January 2013

Fetal porcine dopaminergic cell survival in vitro and its relationship to embryonic age

scientific article published on 01 November 1999

Formation of hippocampal mHTT aggregates leads to impaired spatial memory, hippocampal activation and adult neurogenesis.

scientific article

From molecule to clinic and community for neurodegeneration: research to bridge translational gaps

scientific article published on January 2013

Functional integration of neural grafts in Parkinson's disease

scientific article published on 01 December 1999

G-Force PD: a global initiative in coordinating stem cell-based dopamine treatments for Parkinson's disease

scientific article published on 24 September 2015

GABAergic immunoreactivity is predominant in neurons derived from expanded human neural precursor cells in vitro.

scientific article

GFORCE-PD still going strong in 2016.

scientific article published on 23 February 2017

GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte-neuron interactions

scientific article

Gaucher disease and comorbidities: B-cell malignancy and parkinsonism

scientific article

Genetic and pathological links between Parkinson's disease and the lysosomal disorder Sanfilippo syndrome

scientific article

Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study

scientific article

Getting to the heart of dementia

scientific article

Glucocerebrosidase mutations influence the natural history of Parkinson's disease in a community-based incident cohort.

scientific article

Gold nanoparticles explore cells: cellular uptake and their use as intracellular probes.

scientific article published on 28 February 2014

Graft outcomes influenced by co-expression of Pax7 in graft and host tissue.

scientific article published in March 2009

Graft-induced dyskinesias in Parkinson's disease: what is it all about?

scientific article published on August 2010

Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease?

scientific article published on 22 July 2015

Habitual versus goal-directed action control in Parkinson disease

scientific article

Hand tapping: a simple, reproducible, objective marker of motor dysfunction in Huntington's disease.

scientific article published on 13 May 2008

Health-related quality of life in Huntington's disease: Which factors matter most?

scientific article published in March 2009

Health-related quality of life in Huntington's disease: a comparison of two generic instruments, SF-36 and SIP.

scientific article published in November 2004

Health-related quality of life in early Parkinson's disease: the impact of nonmotor symptoms

scientific article published on 7 October 2013

Heterogeneity of Parkinson's disease in the early clinical stages using a data driven approach.

scientific article

Hippocampal dysfunction defines disease onset in Huntington's disease

scientific article

How common is dementia with Lewy bodies? ⬇️

scientific article published on June 1, 2003

How often does music and rhythm improve patients' perception of motor symptoms in Parkinson's disease?

scientific article published on 12 February 2013

How vital is sleep in Huntington's disease?

scientific article published on 24 March 2010

Human Trials of Stem Cell-Derived Dopamine Neurons for Parkinson's Disease: Dawn of a New Era.

scientific article published in November 2017

Human fetal neural precursor cells can up-regulate MHC class I and class II expression and elicit CD4 and CD8 T cell proliferation

scientific article published on 16 October 2010

Huntingtin Aggregation Impairs Autophagy, Leading to Argonaute-2 Accumulation and Global MicroRNA Dysregulation

scientific article published on 01 August 2018

Huntington disease patients and transgenic mice have similar pro-catabolic serum metabolite profiles

scientific article published on 7 February 2006

Huntington's disease patients have selective problems with insight

scientific article

Huntington's disease: changes in saccades and hand-tapping over 3 years

scientific article published on 29 June 2010

Hypothalamic involvement in Huntington's disease: an in vivo PET study

scientific article published in October 2008

Hypothalamic volume loss is associated with reduced melatonin output in Parkinson's disease

scientific article published on 12 March 2016

Identifying sleep disturbances in Huntington's disease using a simple disease-focused questionnaire

scientific article

Imaging microglial activation in Huntington's disease

scientific article

Immune problems in central nervous system cell therapy.

scientific article

Impaired dimensional selection but intact use of reward feedback during visual discrimination learning in Parkinson's disease.

scientific article published on 10 March 2006

Improving response inhibition in Parkinson's disease with atomoxetine

scientific article

Incidence of early-onset dementias in Cambridgeshire, United Kingdom.

scientific article published in November 2008

Increased capacity for axonal outgrowth using xenogenic tissue in vitro and in a rodent model of Parkinson's disease.

scientific article published on May 2006

Increased thirst and drinking in Huntington's disease and the R6/2 mouse

scientific article published on 9 January 2008

Intra- and inter-network functional alterations in Parkinson's disease with mild cognitive impairment.

scientific article published on 13 January 2017

Intracellular SERS nanoprobes for distinction of different neuronal cell types.

scientific article published on 10 May 2013

Investigation of TGFB2 as a candidate gene in multiple sclerosis and Parkinson’s disease

article

Is there a future for neural transplantation?

scientific article published on January 2004

Journal of Neurology: ready for continued success

scientific article published on 01 January 2013

L-DOPA disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease

scientific article published on 12 July 2006

L-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease

scientific article published in January 2003

L-dopa responsive parkinsonism secondary to a subdural haematoma

scientific article published on 22 April 2013

Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease.

scientific article

Learning to be inflexible: Enhanced attentional biases in Parkinson's disease

scientific article published on 24 May 2016

Lewy bodies in Parkinson's disease: protectors or perpetrators?

scientific article

Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease

scientific article published in October 2006

Long-Term Follow-Up of a Phase I/II Study of ProSavin, a Lentiviral Vector Gene Therapy for Parkinson's Disease

article

Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease.

scientific article published on 20 March 2008

Long-term hibernation of human fetal striatal tissue does not adversely affect its differentiation in vitro or graft survival: implications for clinical trials in Huntington's disease.

scientific article published in January 2003

Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial.

scientific article

Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.

scientific article published on 24 October 2005

Longitudinal diffusion tensor imaging changes in early Parkinson’s disease: ICICLE-PD study

scientific article published on 25 April 2018

Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease

scientific article

MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus

scientific article published in 2021

Making it personal: the prospects for autologous pluripotent stem cell-derived therapies.

scientific article published on 27 June 2016

Microangiopathy of the brain and retina with hearing loss in a 50 year old woman: extending the spectrum of Susac's syndrome.

scientific article

Microglial activation correlates with severity in Huntington disease: a clinical and PET study.

scientific article published in June 2006

Microglial activation in presymptomatic Huntington's disease gene carriers

scientific article

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study

scientific article published in February 2011

Migration and differentiation of transplanted human neural precursor cells

scientific article published in July 2003

Migration of cells from primary transplants of allo- and xenografted foetal striatal tissue in the adult rat brain

scientific article published in March 2005

Mild cognitive impairment and Parkinson's disease--something to remember.

scientific article

Mild cognitive impairment in Parkinson disease: a multicenter pooled analysis.

scientific article

Mild cognitive impairment in Parkinson's disease: millstone or milestone?

scientific article published on 01 April 2013

Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD.

scientific article

Modelling of a targeted nanotherapeutic 'stroma' to deliver the cytokine LIF, or XAV939, a potent inhibitor of Wnt-β-catenin signalling, for use in human fetal dopaminergic grafts in Parkinson's disease

scientific article

Modelling the natural history of Huntington's disease progression.

scientific article published on 16 December 2014

Modern therapeutic approaches in Parkinson's disease.

scientific article published on 28 March 2003

Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

scientific article published on October 2016

Molecular and functional definition of the developing human striatum

scientific article published on 10 November 2014

Monocyte Function in Parkinson's Disease and the Impact of Autologous Serum on Phagocytosis

scientific article published on 16 October 2018

Motor associations of iron accumulation in deep grey matter nuclei in Parkinson's disease: a cross-sectional study of iron-related magnetic resonance imaging susceptibility

scientific article published on 16 December 2016

Movement disorders and psychiatry: Five new things

scientific article published in April 2015

Multimorbidity Predicts Quality of Life but not Motor Severity in Early Parkinson's Disease

scientific article published on 01 January 2018

Mutant huntingtin is present in neuronal grafts in Huntington disease patients

scientific article published on 6 June 2014

Neural Tissue Xenotransplantation: What Is Needed Prior to Clinical Trials in Parkinson's Disease?

scientific article published on March 2000

Neural cells from primary human striatal xenografts migrate extensively in the adult rat CNS.

scientific article published in April 2002

Neural grafting for Parkinson's disease: challenges and prospects.

scientific article published on March 2017

Neural grafting in Parkinson's disease Problems and possibilities

scientific article published on January 2010

Neural transplantation for the treatment of Parkinson's disease

scientific article

Neural transplantation therapies for Parkinson's and Huntington's diseases.

scientific article published in June 2001

Neurodegeneration: a failure of neuroregeneration?

scientific article published on October 2001

Neurodegenerative disease: Mapping the natural history of Huntington disease

scientific article published on 10 December 2013

Neurodegenerative disease: Tracking disease progress in Huntington disease

scientific article published on 15 March 2011

Neurodegenerative disorders: the Glia way forward

scientific article published on 15 July 2014

Neuroendocrine abnormalities in Parkinson's disease

scientific article published on 31 October 2016

Neurogenesis in diseases of the central nervous system.

scientific article published on June 2006

Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment

scientific article published in April 2006

Neuropeptide Y and its role in CNS disease and repair.

scientific article published on 27 September 2012

Neuropeptide Y modifies the disease course in the R6/2 transgenic model of Huntington's disease ⬇️

scientific article published on July 29, 2010

Neuropsychological and clinical heterogeneity of cognitive impairment and dementia in patients with Parkinson's disease

scientific article published on 27 September 2010

Neurotrophic factors as a therapeutic target for Parkinson's disease

scientific article

New approaches for brain repair—from rescue to reprogramming

scientific article published in Nature

New therapeutic approaches to Parkinson's disease including neural transplants.

scientific article

No alterations in α-synuclein gene dosage observed in sporadic Parkinson's disease

article

No evidence for association between an MAOA functional polymorphism and susceptibility to Parkinson's disease.

scientific article

No evidence for association with Parkinson disease for 13 single-nucleotide polymorphisms identified by whole-genome association screening.

scientific article published on June 2006

Normal aging and Parkinson's disease are associated with the functional decline of distinct frontal-striatal circuits

scientific article published on 3 June 2017

Novel Nut and Bolt Task Quantifies Motor Deficits in Premanifest and Manifest Huntington's Disease

scientific article published on 8 September 2015

Novel targets for Huntington's disease: future prospects.

scientific article

OUP accepted manuscript

article by Valentina Gallo et al published 2018 in International Journal of Epidemiology

Olfaction in Parkin single and compound heterozygotes in a cohort of young onset Parkinson's disease patients.

scientific article published on December 2015

Olfactory abnormalities in Huntington's disease: decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients

scientific article

Outcome of cell suspension allografts in a patient with Huntington's disease

scientific article published on 25 October 2018

PAX6 expression may be protective against dopaminergic cell loss in Parkinson's disease.

scientific article published on 20 August 2015

Parkinson disease and growth factors - is GDNF good enough?

scientific article published on 01 June 2019

Parkinson disease: Defining PD subtypes - a step toward personalized management?

scientific article

Parkinson's Disease Case Ascertainment in the EPIC Cohort: The NeuroEPIC4PD Study

scientific article published on 17 September 2015

Parkinson's Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson's Disease, If Anything?

scientific article published on 20 December 2012

Parkinson's disease and 2009: recent advances

scientific article published on 08 April 2010

Parkinson's disease and growth factors - are they the answer?

scientific article

Parkinson's disease and healthy aging: independent and interacting effects on action selection

scientific article

Parkinson's disease--the continuing search for biomarkers

scientific article published on 03 February 2011

Parkinson's disease: an autoimmune process

scientific article published on 01 November 1988

Patients Beware: Commercialized Stem Cell Treatments on the Web

scientific article published on 17 June 2010

Pax7 expression in the adult rat superior colliculus following optic nerve injury.

scientific article published in January 2007

Perseveration and choice in Parkinson's disease: the impact of progressive frontostriatal dysfunction on action decisions

scientific article published on June 2012

Personality affects aspects of health-related quality of life in Parkinson's disease via psychological coping strategies

scientific article

Planning ability in Parkinson's disease is influenced by the COMT val158met polymorphism

scientific article

Platelet abnormalities in Huntington's disease.

scientific article

Platelet-derived extracellular vesicles in Huntington's disease

scientific article published on 12 September 2018

Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease

scientific article published on 05 November 2018

Posterior communicating artery aneurysm presenting with haemorrhage into an arachnoid cyst.

scientific article

Predicting beneficial effects of atomoxetine and citalopram on response inhibition in Parkinson's disease with clinical and neuroimaging measures

scientific article published on 12 January 2016

Predicting clinical diagnosis in Huntington's disease: An imaging polymarker

scientific article published on 5 February 2018

Prediction of cognition in Parkinson's disease with a clinical-genetic score: a longitudinal analysis of nine cohorts

scientific article published on 16 June 2017

Prediction of manifest Huntington's disease with clinical and imaging measures: a prospective observational study

scientific article

Predictors of Parkinson's disease dementia: towards targeted therapies for a heterogeneous disease.

scientific article published on January 2014

Predictors of punding in Parkinson's disease: results from a questionnaire survey

scientific article published in December 2007

Prevalence of the LRRK2 G2019S mutation in a UK community based idiopathic Parkinson's disease cohort.

scientific article

Pridopidine for the treatment of motor function in patients with Huntington's disease (MermaiHD): a phase 3, randomised, double-blind, placebo-controlled trial

scientific article

Profile of cognitive progression in early Huntington's disease.

scientific article published on December 2003

Progress in Huntington's disease: the search for markers of disease onset and progression

scientific article published on 21 March 2015

Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study.

scientific article published in May 2003

Pseudo-neglect in Huntington's disease correlates with decreased angular gyrus density.

scientific article published in April 2004

Putative cortical dopamine levels affect cortical recruitment during planning.

scientific article published on August 2013

Quality of life and mild cognitive impairment in early Parkinson's disease: does subtype matter?

scientific article

Quantitative evaluation of the human subventricular zone.

scientific article

REST suppression mediates neural conversion of adult human fibroblasts via microRNA-dependent and -independent pathways

scientific article

RNA velocity of single cells

scientific article published in Nature

Random number generation in patients with symptomatic and presymptomatic Huntington's disease

scientific article published in December 2004

Rapid decline in motor symptoms in HD neural transplant patients prior to surgery.

scientific article published in March 2004

Rate and acceleration of whole-brain atrophy in premanifest and early Huntington's disease

scientific article published on May 2010

Rating Apathy in Huntington’s Disease: Patients and Companions Agree

scientific article

Regenerative Therapies for Parkinson's Disease: An Update

scientific article published on 01 August 2018

Regional expression of the MAPT gene is associated with loss of hubs in brain networks and cognitive impairment in Parkinson disease and progressive supranuclear palsy

scientific article

Regulation of stem cell therapies under attack in Europe: for whom the bell tolls

scientific article published on 3 May 2013

Relapsing encephalopathy in a patient with alpha-methylacyl-CoA racemase deficiency.

scientific article published on 21 November 2007

Relapsing encephalopathy in a patient with α-methylacyl-CoA racemase deficiency

scientific article

Relationship between CAG repeat length and brain volume in premanifest and early Huntington's disease

scientific article published in February 2009

Repairing the brain in Parkinson's disease: where next?

scientific article

Retrospective assessment of movement disorder society criteria for mild cognitive impairment in Parkinson's disease.

scientific article published on 10 February 2015

Review: The spectrum of clinical features seen with alpha synuclein pathology.

scientific article

Revisiting the effects of Parkinson's disease and frontal lobe lesions on task switching: the role of rule reconfiguration

scientific article published on 20 December 2012

Role of brain imaging in early parkinsonism

scientific article published in the British Medical Journal

SCA2 presenting as levodopa-responsive parkinsonism in a young patient from the United Kingdom: a case report

scientific article

Saccadic latency distributions in Parkinson's disease and the effects of L-dopa

scientific article published on 17 March 2006

Saccadic latency in Parkinson's disease correlates with executive function and brain atrophy, but not motor severity.

scientific article

Saccadometry: a new tool for evaluating presymptomatic Huntington patients

scientific article

Selective serotonin reuptake inhibition modulates response inhibition in Parkinson's disease

scientific article published on 27 February 2014

Serum Raman spectroscopy as a diagnostic tool in patients with Huntington's disease

scientific article published on 14 November 2019

Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD).

scientific article

Setting Global Standards for Stem Cell Research and Clinical Translation: The 2016 ISSCR Guidelines

scientific article published on 11 May 2016

Severity of mild cognitive impairment in early Parkinson's disease contributes to poorer quality of life

scientific article

Sham neurosurgical procedures in clinical trials for neurodegenerative diseases: scientific and ethical considerations

scientific article published on 01 July 2012

Simple Generation of a High Yield Culture of Induced Neurons from Human Adult Skin Fibroblasts.

scientific article published on 5 February 2018

Skin and platelet alpha-synuclein as peripheral biomarkers of Parkinson's disease

scientific article published on 02 March 2005

Sleep and circadian rhythm regulation in early Parkinson disease

scientific article

Sleep deficits but no metabolic deficits in premanifest Huntington's disease

scientific article published on 29 July 2015

Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment

scientific article

Spatial structure normalises working memory performance in Parkinson's disease

scientific article published in September 2017

Specifically neuropathic Gaucher's mutations accelerate cognitive decline in Parkinson's

scientific article published on 22 September 2016

Stability of mild cognitive impairment in newly diagnosed Parkinson's disease

scientific article published on March 2017

Statins are underused in recent-onset Parkinson's disease with increased vascular risk: findings from the UK Tracking Parkinson's and Oxford Parkinson's Disease Centre (OPDC) discovery cohorts

scientific article published on 26 September 2016

Stem cell therapies for Parkinson's disease: are trials just around the corner?

scientific article published in January 2014

Stem cells and neurodegenerative diseases: where is it all going?

scientific article

Stem cells and neurological disease.

scientific article published in May 2003

Stem cells and regenerative therapies for Parkinson's disease.

scientific article published on 15 July 2012

Stem cells and the treatment of Parkinson's disease

scientific article published on 06 January 2013

Strategies for bringing stem cell-derived dopamine neurons to the clinic: A European approach (STEM-PD).

scientific article published on 07 February 2017

Striatal allografts in patients with Huntington's disease: impact of diminished astrocytes and vascularization on graft viability.

scientific article published on 31 January 2013

Striatal contributions to working memory: a functional magnetic resonance imaging study in humans.

scientific article published in February 2004

Successful treatment of intractable epilepsia partialis continua with multiple subpial transections.

scientific article published on July 1998

Switching between abstract rules reflects disease severity but not dopaminergic status in Parkinson's disease

scientific article published on 8 January 2009

Systematic review and UK-based study of PARK2 (parkin), PINK1, PARK7 (DJ-1) and LRRK2 in early-onset Parkinson's disease

scientific article published on 06 September 2012

TRACKING PARKINSON'S (THE PROBAND STUDY)–INTERIM REPORT FROM THE FIRST 1000 CASES

scholarly article by Donald Grosset et al published 9 October 2013 in Journal of Neurology, Neurosurgery and Psychiatry

Tackling Ethical Challenges of Premature Delivery of Stem Cell-Based Therapies: ISSCR 2018 Annual Meeting Focus Session Report

scientific article published on 01 November 2018

Targeting impulsivity in Parkinson's disease using atomoxetine

scientific article

Task-Set Switching Deficits in Early-Stage Huntington's Disease: Implications for Basal Ganglia Function

Task-set switching deficits in early-stage Huntington's disease: implications for basal ganglia function

scientific article published in July 2003

Tau acts as an independent genetic risk factor in pathologically proven PD.

scientific article published on 4 January 2012

Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease

scientific article published on August 2007

The Addenbrooke's Cognitive Examination for the differential diagnosis and longitudinal assessment of patients with parkinsonian disorders

scientific article published on 8 January 2013

The Addenbrooke's Cognitive Examination-Revised accurately detects cognitive decline in Huntington's disease

scientific article published on 07 August 2013

The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson's disease

scientific article

The CamPaIGN study of Parkinson's disease: 10-year outlook in an incident population-based cohort

scientific article published on 18 June 2013

The Cambridge Behavioural Inventory revised

scientific article published in April 2008

The Challenges of First-in-Human Stem Cell Clinical Trials: What Does This Mean for Ethics and Institutional Review Boards?

scientific article

The Current Status of Neural Grafting in the Treatment of Huntington's Disease. A Review

scientific article published on 7 December 2011

The Peripheral Inflammatory Response to Alpha-Synuclein and Endotoxin in Parkinson's Disease

scientific article published on 20 November 2018

The basal ganglia and pain.

scientific article published on July 1988

The basal ganglia and rule-governed language use: evidence from vascular and degenerative conditions.

scientific article published on 19 January 2005

The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study

scientific article published in August 2012

The cellular repair of the brain in Parkinson's disease--past, present and future.

scientific article published on April 2004

The central clock in patients with Parkinson disease--reply

scientific article published in November 2014

The challenges of administering cell-based therapies to patients with Parkinson's disease

scientific article published on December 2013

The clinical heterogeneity of Parkinson's disease and its therapeutic implications

scientific article published on 14 October 2018

The cognitive ability of an incident cohort of Parkinson's patients in the UK. The CamPaIGN study

scientific article published on 22 December 2003

The current clinical management of Huntington's disease

scientific article published on August 2008

The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort

scientific article published on 07 October 2009

The effect of multidisciplinary rehabilitation on brain structure and cognition in Huntington's disease: an exploratory study.

scientific article

The effect of truncated human alpha-synuclein (1-120) on dopaminergic cells in a transgenic mouse model of Parkinson's disease

scientific article published on 01 January 2007

The effects of modafinil on mood and cognition in Huntington's disease

scientific article published in June 2008

The effects of multidisciplinary rehabilitation in patients with early-to-middle-stage Huntington's disease: a pilot study.

scientific article

The emerging technologies of neural xenografting and stem cell transplantation for treating neurodegenerative disorders.

scientific article published on February 2004

The factor structure of the UPDRS as an index of disease progression in Parkinson's disease

scientific article

The future challenges in Parkinson's disease

scientific article published on March 2004

The future of cell therapies in the treatment of Parkinson's disease

scientific article published on October 2007

The genetic basis of Parkinson's disease

scientific article

The glial response to intracerebrally delivered therapies for neurodegenerative disorders: is this a critical issue?

scientific article

The heterogeneity of idiopathic Parkinson's disease

scientific article

The human cytomegalovirus non-coding Beta2.7 RNA as a novel therapeutic for Parkinson's disease--Translational research with no translation

scientific article published on 21 May 2015

The importance of A9 dopaminergic neurons in mediating the functional benefits of fetal ventral mesencephalon transplants and levodopa-induced dyskinesias

scientific article published on 22 December 2006

The incidence of Parkinson's disease in the North-East of England

scientific article published on 23 July 2013

The long-term safety and efficacy of bilateral transplantation of human fetal striatal tissue in patients with mild to moderate Huntington's disease

scientific article (publication date: June 2013)

The metabolic profile of early Huntington's disease--a combined human and transgenic mouse study

scientific article published on 19 January 2008

The motor and cognitive features of Parkinson's disease in patients with concurrent Gaucher disease over 2 years: a case series.

scientific article published on 29 May 2018

The natural history of treated Parkinson's disease in an incident, community based cohort

scientific article published on 18 May 2011

The neurological assessment of patients in vegetative and minimally conscious states

scientific article published on 01 July 2005

The neurology community mourns the passing of Dr. John F. Kurtzke.

scientific article published on 25 February 2016

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro

scientific article published on 12 May 2014

The potential for circuit reconstruction by expanded neural precursor cells explored through porcine xenografts in a rat model of Parkinson's disease

scientific article

The potential of GDNF as a treatment for Parkinson's disease

scientific article published on January 2004

The progression of regional atrophy in premanifest and early Huntington's disease: a longitudinal voxel-based morphometry study

scientific article published in December 2009

The relation between anger and different forms of disgust: implications for emotion recognition impairments in Huntington's disease

scientific article published on 16 May 2010

The relationship between abnormalities of saccadic and manual response times in Parkinson's disease.

scientific article

The role of anxiety in the development of levodopa-induced dyskinesias in an animal model of Parkinson's disease, and the effect of chronic treatment with the selective serotonin reuptake inhibitor citalopram.

scientific article published on 23 December 2007

The role of learned irrelevance in attentional set-shifting impairments in Parkinson's disease

scientific article published in September 2006

The role of tau in the pathological process and clinical expression of Huntington's disease

scientific article

The role of the amygdala during emotional processing in Huntington's disease: from pre-manifest to late stage disease

scientific article published on 17 February 2015

The search for biomarkers in Parkinson's disease: a critical review.

scientific article published on December 2008

The spectrum of cognitive impairment in Lewy body diseases

scientific article

The spectrum of nonmotor symptoms in early Parkinson disease

scientific article published on January 2013

The use of the Actiwatch-Neurologica system to objectively assess the involuntary movements and sleep-wake activity in patients with mild-moderate Huntington's disease

scientific article published on 7 March 2005

The usefulness of a modified adult protocol for the clearance of paediatric cervical spine injury in the emergency department.

scientific article published in April 2003

The utility of the Cambridge Behavioural Inventory in neurodegenerative disease.

scientific article

The val158met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease

scientific article published on 27 August 2008

Time course of dopamine neuron loss and glial response in the 6-OHDA striatal mouse model of Parkinson's disease.

scientific article published on 26 December 2013

Time on timing: Dissociating premature responding from interval sensitivity in Parkinson's disease

scientific article published on 19 April 2016

Toll-like receptor expression in the blood and brain of patients and a mouse model of Parkinson's disease

scientific article published on 7 December 2014

Top-down attentional control in Parkinson's disease: salient considerations

scientific article published in May 2010

Tracking Parkinson's: Study Design and Baseline Patient Data

scientific article

Transplantation of expanded neural precursor cells from the developing pig ventral mesencephalon in a rat model of Parkinson's disease

scientific article

Transplanted human neural precursor cells migrate widely but show no lesion-specific tropism in the 6-hydroxydopamine rat model of Parkinson's disease.

scientific article published in January 2006

Treating Parkinson's disease in the 21st century: can stem cell transplantation compete?

scientific article

Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell

article by Gerda Kildisiute et al published February 2021 in Science Advances

Two-stage association study and meta-analysis of mitochondrial DNA variants in Parkinson disease

scientific article published on 03 May 2013

UCHL-1 is not a Parkinson's disease susceptibility gene

scientific article published in April 2006

Understanding the dopaminergic deficits in Parkinson's disease: insights into disease heterogeneity

scientific article published on 13 March 2009

Using Medical Claims Analyses to Understand Interventions for Parkinson Patients

scientific article

Using a smartphone-based self-management platform to support medication adherence and clinical consultation in Parkinson's disease

scientific article

Using executive heterogeneity to explore the nature of working memory deficits in Parkinson's disease

scientific article published on January 2003

Utility of the new Movement Disorder Society clinical diagnostic criteria for Parkinson's disease applied retrospectively in a large cohort study of recent onset cases

scientific article published on 12 April 2017

Variation in Recent Onset Parkinson's Disease: Implications for Prodromal Detection

scientific article published on 19 March 2016

Vascular disease and vascular risk factors in relation to motor features and cognition in early Parkinson's disease

scientific article published on 21 June 2016

Vascular parkinsonism: a review of the precision and frequency of the diagnosis

scientific article

Verbal fluency in Huntington's disease: a longitudinal analysis of phonemic and semantic clustering and switching

scientific article published on January 2002

Visual hallucinations predict increased benefits from rivastigmine in Parkinson's disease dementia.

scientific article published on 20 March 2007

Visualising disease progression on multiple variables with vector plots and path plots

scientific article

Voices of biotech

scientific article published on March 2016

What is the most promising treatment for Parkinson's disease: genes, cells, growth factors or none of the above?

scientific article published on 01 September 2012

Which patients with Parkinson's disease participate in clinical trials? One centre's experiences with a new cell based therapy trial (TRANSEURO).

scientific article published on January 2014

White matter pathology in Parkinson's disease: the effect of imaging protocol differences and relevance to executive function

scientific article

Whole-brain atrophy as a measure of progression in premanifest and early Huntington's disease

scientific article published in April 2009

iPSC Modeling of Presenilin1 Mutation in Alzheimer's Disease with Cerebellar Ataxia

scientific article published on 31 October 2018

α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function.

scientific article published on 12 September 2016

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