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List of works by Genhong Cheng

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Toll-like Receptor 3–Mediated Suppression of TRAMP Prostate Cancer Shows the Critical Role of Type I Interferons in Tumor Immune Surveillance

scientific article published on March 16, 2010
Unique CD40-mediated biological program in B cell activation requires both type 1 and type 2 NF-kappaB activation pathways

scientific article
Cathelicidin signaling via the Toll-like receptor protects against colitis in mice

scientific article published on 14 July 2011
TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response

scientific article published on July 2006
Type I IFN Promotes IL-10 Production from T Cells to Suppress Th17 Cells and Th17-Associated Autoimmune Inflammation

scientific article published on December 6, 2011
Chloroquine, a FDA-approved Drug, Prevents Zika Virus Infection and its Associated Congenital Microcephaly in Mice

scientific article
Key molecular contacts promote recognition of the BAFF receptor by TNF receptor-associated factor 3: implications for intracellular signaling regulation

scientific journal article
Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1

scientific journal article
PLP2 of Mouse Hepatitis Virus A59 (MHV-A59) Targets TBK1 to Negatively Regulate Cellular Type I Interferon Signaling Pathway

scientific article published on February 18, 2011
Influenza Virus Affects Intestinal Microbiota and Secondary Salmonella Infection in the Gut through Type I Interferons

scientific article (publication date: May 2016)
Interferon-Inducible Cholesterol-25-Hydroxylase Inhibits Hepatitis C Virus Replication via Distinct Mechanisms

scientific article published on December 3, 2014
Selective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses

scientific article published on November 4, 2013
Positive feedback regulation of type I interferon by the interferon‐stimulated gene STING

scientific article published on January 8, 2015
PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins

scientific article published on 19 June 2018
Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation

scientific article
Toll-like receptors and innate antiviral responses

scientific article
Positive Feedback Regulation of Type I IFN Production by the IFN-Inducible DNA Sensor cGAS

scientific article published on January 21, 2015
A triclade DNA vaccine designed on the basis of a comprehensive serologic study elicits neutralizing antibody responses against all clades and subclades of highly pathogenic avian influenza H5N1 viruses

scientific article
LILRA2 activation inhibits dendritic cell differentiation and antigen presentation to T cells

scientific article published on December 2007
TLR agonists regulate PDGF-B production and cell proliferation through TGF-beta/type I IFN crosstalk

scientific article
TRAF3 and its biological function

scientific article published on January 2007
Cascade search for HSV-1 combinatorial drugs with high antiviral efficacy and low toxicity

scientific article published on May 10, 2012
A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections

scientific article
The interferon response to bacterial and viral infections

scientific article published in January 2006
IRF3-dependent type I interferon response in B cells regulates CpG-mediated antibody production

scientific article published on 9 October 2007
Single Amino Acid Substitutions Confer the Antiviral Activity of the TRAF3 Adaptor Protein onto TRAF5

scientific article
Retinoid X receptor α attenuates host antiviral response by suppressing type I interferon

scientific article published on November 24, 2014
TRIM14 inhibits hepatitis C virus infection by SPRY domain-dependent targeted degradation of the viral NS5A protein

scientific article
T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK(1).

scientific article
From plankton to pathogen recognition

article
New insights into the structural basis of DNA recognition by HINa and HINb domains of IFI16

scientific article published on August 5, 2015
NF-κB: Much Learned, Much to Learn

scientific article published on September 7, 2010
A repetitive region of gammaherpesvirus genomic DNA is a ligand for induction of type I interferon

scientific article published on 12 December 2007
The hepatitis C virus protein NS3 suppresses TNF-α-stimulated activation of NF-κB by targeting LUBAC.

scientific article
E90 subunit vaccine protects mice from Zika virus infection and microcephaly

scholarly article by Xing-Liang Zhu et al published 10 August 2018 in Acta neuropathologica communications
A MyD88-dependent IFNγR-CCR2 signaling circuit is required for mobilization of monocytes and host defense against systemic bacterial challenge

scientific article
IL-27 Suppresses Antimicrobial Activity in Human Leprosy

scientific article published on June 1, 2015
Structural basis for DNA recognition by STAT6.

scientific article
Zika virus shedding in the stool and infection through the anorectal mucosa in mice

scholarly article published by Yong-Qiang Deng in 2018
Polyinosinic-polycytidylic acid suppresses acetaminophen-induced hepatotoxicity independent of type I interferons and toll-like receptor 3

scientific article
Generation of a Live Attenuated Influenza Vaccine that Elicits Broad Protection in Mice and Ferrets

scientific article
NOD so fast: NLRX1 puts the brake on inflammation

scientific article
Biomarkers and immunoprofiles associated with fetal abnormalities of ZIKV-positive pregnancies

scholarly article by Suan-Sin Foo et al published 2 November 2018 in JCI insight
Complex Regulation Pattern of IRF3 Activation Revealed by a Novel Dimerization Reporter System

scientific article published on 04 April 2016
Disruption of Type I Interferon Induction by HIV Infection of T Cells

scientific article published on September 16, 2015
Crystal structure of the ubiquitin-like domain of human TBK1

scientific article published on May 20, 2012
Structural and functional analyses of human DDX41 DEAD domain

scientific article published on 7 December 2016
Type I IFN augments IL-27-dependent TRIM25 expression to inhibit HBV replication

scientific article published on 13 February 2017
TANK-Binding Kinase 1 Attenuates PTAP-Dependent Retroviral Budding through Targeting Endosomal Sorting Complex Required for Transport-I

scientific article published on January 26, 2011
Macrophage differentiation from embryoid bodies derived from human embryonic stem cells

scientific article

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