List of works by Matthew Breen

A canine cancer-gene microarray for CGH analysis of tumors.

scientific article published in January 2003

A comprehensive genomic history of extinct and living elephants.

scientific article published on 26 February 2018

A cytogenetically characterized, genome-anchored 10-Mb BAC set and CGH array for the domestic dog.

scientific article published on 16 August 2007

A genome assembly-integrated dog 1 Mb BAC microarray: a cytogenetic resource for canine cancer studies and comparative genomic analysis

scientific article

A genome-wide approach to comparative oncology: high-resolution oligonucleotide aCGH of canine and human osteosarcoma pinpoints shared microaberrations

scientific article published on 6 November 2012

A mutation in the canine BHD gene is associated with hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis in the German Shepherd dog.

scientific article

A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity.

scientific article

Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas: a pattern distinct from other sarcomas with complex genomics.

scientific article

An integrated 4249 marker FISH/RH map of the canine genome

scientific article

Anchoring the dog to its relatives reveals new evolutionary breakpoints across 11 species of the Canidae and provides new clues for the role of B chromosomes.

scientific article published on August 2011

Aniridia-associated cytogenetic rearrangements suggest that a position effect may cause the mutant phenotype

scientific article published on March 1995

Array-based comparative genomic hybridization-guided identification of reference genes for normalization of real-time quantitative polymerase chain reaction assay data for lymphomas, histiocytic sarcomas, and osteosarcomas of dogs.

scientific article

Association of breed and histopathological grade in canine mast cell tumours.

scientific article

BRAF Mutations in Canine Cancers

scientific article published on 8 June 2015

Bovine papillomavirus type 4 DNA isolated from a skin lesion in a steer

scientific article published on 01 April 1996

Bovine papillomavirus type 4 in Australia

scientific article published on 01 July 1995

CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies

scientific article published on 3 February 2012

Canine Histiocytic Malignancies-Challenges and Opportunities

scientific article published on 4 January 2016

Canine TCOF1; cloning, chromosome assignment and genetic analysis in dogs with different head types.

scientific article

Canine homolog of the T-box transcription factor T; failure of the protein to bind to its DNA target leads to a short-tail phenotype.

scientific article published in March 2001

Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium.

scientific article published on May 2004

Canine prostate cancer cell line (Probasco) produces osteoblastic metastases in vivo

scientific article

Canine urothelial carcinoma: genomically aberrant and comparatively relevant.

scientific article published on 18 March 2015

Characterization of canine osteosarcoma by array comparative genomic hybridization and RT-qPCR: signatures of genomic imbalance in canine osteosarcoma parallel the human counterpart.

scientific article published on 11 August 2011

Characterization of twelve new horse microsatellite loci: AHT12-AHT23

scientific article published on 01 December 1997

Chromosomal assignment of the canine melanophilin gene (MLPH): a candidate gene for coat color dilution in Pinschers.

scientific article published on 15 June 2005

Chromosome aberrations in canine multicentric lymphomas detected with comparative genomic hybridisation and a panel of single locus probes

scientific article published on October 2003

Chromosome-specific single-locus FISH probes allow anchorage of an 1800-marker integrated radiation-hybrid/linkage map of the domestic dog genome to all chromosomes

scientific article

Cloning and chromosomal localization of MX1 and ETS2 to chromosome 26 of the horse (Equus caballus)

scientific article

Cloning of the canine gene encoding transcription factor Pit-1 and its exclusion as candidate gene in a canine model of pituitary dwarfism.

scientific article

Comparative Aspects of BRAF Mutations in Canine Cancers

scientific article published on 24 August 2015

Comparative cytogenetic characterization of primary canine melanocytic lesions using array CGH and fluorescence in situ hybridization

scientific article

Comparative genomic hybridization (CGH) in dogs--application to the study of a canine glial tumour cell line.

scientific article published on July 2000

Comparative oncology: what dogs and other species can teach us about humans with cancer

scientific article

Comprehensive genomic characterization of five canine lymphoid tumor cell lines

scientific article

Constitutive activation of alternative nuclear factor kappa B pathway in canine diffuse large B-cell lymphoma contributes to tumor cell survival and is a target of new adjuvant therapies

scientific article published on 08 December 2016

Construction and integration of radiation-hybrid and cytogenetic maps of dog Chromosome X.

scientific article published in March 2003

Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors

scientific article

Creation of an NCI comparative brain tumor consortium: informing the translation of new knowledge from canine to human brain tumor patients.

scientific article published on 14 May 2016

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts

scientific article

Detection of BRAF Mutation in Urine DNA as a Molecular Diagnostic for Canine Urothelial and Prostatic Carcinoma

scientific article published on 9 December 2015

Detection of Copy Number Imbalance in Canine Urothelial Carcinoma With Droplet Digital Polymerase Chain Reaction

scientific article published on 16 November 2015

Detection of equine X chromosome abnormalities inequids using a horse X whole chromosome paint probe (WCPP) ⬇️

scientific article published on May 1, 1997

Development of a brain metastatic canine prostate cancer cell line.

scientific article

Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk

scientific article

Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ).

scientific article published on January 2008

Evaluation of gene expression and DNA copy number profiles of adipose tissue-derived stromal cells and consecutive neurosphere-like cells generated from dogs with naturally occurring spinal cord injury

scientific article published in March 2017

Exclusion of galectin 9 as a candidate gene for hyperuricosuria in the Dalmatian dog.

scientific article

Extensive conservation of genomic imbalances in canine transmissible venereal tumors (CTVT) detected by microarray-based CGH analysis.

scientific article published on 30 September 2009

FISH mapping and identification of canine chromosomes.

scientific article published on January 1999

FLT3 mutations in canine acute lymphocytic leukemia

scientific article

First comprehensive low-density horse linkage map based on two 3-generation, full-sibling, cross-bred horse reference families

scientific article published on 01 June 2000

Gene profiling of canine B-cell lymphoma reveals germinal center and postgerminal center subtypes with different survival times, modeling human DLBCL.

scientific article published on 19 June 2013

Generation and characterization of novel canine malignant mast cell line CL1.

scientific article published on 11 October 2008

Generation of LIF-independent induced pluripotent stem cells from canine fetal fibroblasts

scientific article published on 8 January 2017

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

scientific article

Genome sequence, comparative analysis and haplotype structure of the domestic dog

scientific article

Genome-wide DNA copy number analysis and targeted transcriptional analysis of canine histiocytic malignancies identifies diagnostic signatures and highlights disruption of spindle assembly complex

scientific article published on 23 April 2019

Genome-wide analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B

scientific article

Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation

scientific article published on 3 June 2015

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers

scientific article

Genomic organization of the dog dystroglycan gene DAG1 locus on chromosome 20q15.1-q15.2.

scientific article

Genomic profiling of canine mast cell tumors identifies DNA copy number aberrations associated with KIT mutations and high histological grade

scientific article

Genomic profiling reveals extensive heterogeneity in somatic DNA copy number aberrations of canine hemangiosarcoma

scientific article

Genomic sequences of bovine papillomaviruses in formalin-fixed sarcoids from Australian horses revealed by polymerase chain reaction

scientific article published on 01 July 1994

Growth kinetics of endosymbiont Wolbachia in the common bed bug, Cimex lectularius

scientific article published in Scientific Reports

IDH1 and IDH2 hotspot mutations are not found in canine glioma.

scientific article published on July 2010

Identification of papillomaviruses in scrapings from bovine warts by use of the polymerase chain reaction.

scientific article published in January 1997

Identification of three molecular and functional subtypes in canine hemangiosarcoma through gene expression profiling and progenitor cell characterization.

scientific article published on 11 February 2014

Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-cell lymphoma

scientific article published on 01 July 2007

Integrated immunohistochemical and DNA copy number profiling analysis provides insight into the molecular pathogenesis of canine follicular lymphoma.

scientific article published on 2 May 2016

Interactions between CXCR4 and CXCL12 promote cell migration and invasion of canine hemangiosarcoma

scientific article published on 3 September 2015

Interleukin-12 inhibits tumor growth in a novel angiogenesis canine hemangiosarcoma xenograft model.

scientific article

Intracoronary allogeneic cardiosphere-derived stem cells are safe for use in dogs with dilated cardiomyopathy.

scientific article

Intrageneric amplification of horse microsatellite markers with emphasis on the Przewalski's horse (E. pmewalskii) ⬇️

scientific article published on 01 December 1994

Malignant canine mammary tumours: Preliminary genomic insights using oligonucleotide array comparative genomic hybridisation analysis.

scientific article published on 28 March 2017

Mature hair follicles generated from dissociated cells: A universal mechanism of folliculoneogenesis

article

Microarray analysis of differentially expressed genes of primary tumors in the canine central nervous system.

scientific article

Microarray-based cytogenetic profiling reveals recurrent and subtype-associated genomic copy number aberrations in feline sarcomas

scientific article published on 26 November 2009

Molecular cytogenetic analysis of a novel high-grade canine T-lymphoblastic lymphoma demonstrating co-expression of CD3 and CD79a cell markers.

scientific article published on January 2001

Molecular profiling reveals prognostically significant subtypes of canine lymphoma

scientific article

Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach

scientific article

Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma.

scientific article published on September 2005

Naturally occuring canine cancers: powerful models for stimulating pharmacogenomic advancement in human medicine.

scientific article published in December 2013

Origins and evolution of a transmissible cancer.

scientific article

Partial cytogenetic response with toceranib and prednisone treatment in a young dog with chronic monocytic leukemia.

scientific article published in November 2013

Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.

scientific article published on February 2016

Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma

scientific article

Peto's paradox and the promise of comparative oncology

scientific article

Physical and linkage mapping of the canine phosphate carrier (SLC25A3) and apoptotic activating factor 1 (APAF1) genes to canine chromosome 15.

scientific article published on February 2001

Predictive value of p16 or Rb inactivation in a model of naturally occurring canine non-Hodgkin's lymphoma

scientific article published on 21 September 2006

Reading between the lines: molecular characterization of five widely used canine lymphoid tumour cell lines.

scientific article published on 23 November 2011

Reciprocal chromosome painting reveals detailed regions of conserved synteny between the karyotypes of the domestic dog (Canis familiaris) and human.

scientific article published on October 1999

Relationship Between Sequence Homology, Genome Architecture, and Meiotic Behavior of the Sex Chromosomes in North American Voles

scientific article published on 12 July 2018

SETD2 Is Recurrently Mutated in Whole-Exome Sequenced Canine Osteosarcoma

scientific article published on 03 May 2018

Safe and Effective Sarcoma Therapy through Bispecific Targeting of EGFR and uPAR.

scientific article published on 13 February 2017

Sequence analysis of RAS and RAF mutation hot spots in canine carcinoma.

scientific article published on 6 October 2016

Somatic inactivating PTPRJ mutations and dysregulated pathways identified in canine malignant melanoma by integrated comparative genomic analysis

scientific article published on 06 September 2018

The Dog Gene Map

scientific article published on 01 January 1998

The MTAP-CDKN2A locus confers susceptibility to a naturally occurring canine cancer

scientific article

The cnm locus, a canine homologue of human autosomal forms of centronuclear myopathy, maps to chromosome 2.

scientific article published on 23 July 2003

The dog as a cancer model

article

The genome of the green anole lizard and a comparative analysis with birds and mammals ⬇️

scientific article

The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification

scientific article

The search for a marsupial XIC reveals a break with vertebrate synteny.

scientific article published on 5 March 2007

Three crocodilian genomes reveal ancestral patterns of evolution among archosaurs

scientific article

Update on genomics in veterinary oncology.

scientific article

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