Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Philipp E. Scherer

5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver

scientific article published on 31 October 2010

A Novel Model of Diabetic Complications: Adipocyte Mitochondrial Dysfunction Triggers Massive β-Cell Hyperplasia

scientific article published on 27 December 2019

A Prospective Analysis of Plasma Adiponectin and Risk of Incident Cancer: The Dallas Heart Study

scientific article published on July 2015

A Role of the Inflammasome in the Low Storage Capacity of the Abdominal Subcutaneous Adipose Tissue in Obese Adolescents

scientific article published on 30 December 2015

A dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation

scientific article

A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21

scientific article published on 17 December 2020

A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome

scientific article published in July 2002

A novel ADIPOQ mutation (p.M40K) impairs assembly of high-molecular-weight adiponectin and is associated with early-onset obesity and metabolic syndrome

scientific article published on 16 January 2014

A prospective study of inflammation markers and endometrial cancer risk in postmenopausal hormone nonusers

scientific article

A proteomic approach for identification of secreted proteins during the differentiation of 3T3-L1 preadipocytes to adipocytes.

scientific article published on March 2002

A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity

scientific article published on 23 October 2003

ACDC/Adiponectin Polymorphisms Are Associated With Severe Childhood and Adult Obesity

scientific article published on 01 February 2006

ACRP30/adiponectin: an adipokine regulating glucose and lipid metabolism

scientific article

ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection

scientific article

Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases

scientific article published on 20 December 2012

Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice

scientific article published on 9 December 2017

Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats

scientific article published in May 2005

Adipocyte Gs but not Gi signaling regulates whole-body glucose homeostasis

scientific article published on 22 June 2019

Adipocyte Xbp1s overexpression drives uridine production and reduces obesity

scientific article published on 2 March 2018

Adipocyte differentiation induces dynamic changes in NF-kappaB expression and activity

scientific article published on 13 July 2004

Adipocyte inflammation is essential for healthy adipose tissue expansion and remodeling

scientific article

Adipocyte metabolism and obesity

scientific article

Adipocyte, adipose tissue, and infectious disease

scientific article published on 21 November 2006

Adipocyte-Specific Deletion of Manganese Superoxide Dismutase Protects From Diet-Induced Obesity Through Increased Mitochondrial Uncoupling and Biogenesis

scientific article published on 9 June 2016

Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment

scientific article

Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment

Adipocyte-derived endotrophin promotes malignant tumor progression ⬇️

scientific article published on October 8, 2012

Adipocyte-derived factors potentiate nutrient-induced production of plasminogen activator inhibitor-1 by macrophages

scientific article published in February 2010

Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia.

scientific article

Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization ⬇️

scientific article published on September 25, 2003

Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease

scientific article

Adipocytes: impact on tumor growth and potential sites for therapeutic intervention

scientific article

Adipogenesis and metabolic health

scientific article published on 01 April 2019

Adipokines as novel biomarkers and regulators of the metabolic syndrome ⬇️

scientific article published on November 1, 2010

Adipokines linking obesity with colorectal cancer risk in postmenopausal women

scientific article published on 17 April 2012

Adiponectin Moderates Antidepressant Treatment Outcome in the Combining Medications to Enhance Depression Outcomes Randomized Clinical Trial

scientific article published on 21 June 2018

Adiponectin Regulation of Stellate Cell Activation via PPARγ-Dependent and -Independent Mechanisms ⬇️

scientific article published on June 1, 2011

Adiponectin acts in the brain to decrease body weight.

scientific article

Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression

scientific article published on 30 November 2016

Adiponectin and cardiometabolic trait and mortality: where do we go?

scientific article published in 2021

Adiponectin and cardiovascular risk profile in patients with type 2 diabetes mellitus: parameters associated with adiponectin complex distribution ⬇️

scientific article published on 09 May 2011

Adiponectin and leptin levels in HIV-infected subjects with insulin resistance and body fat redistribution

scientific article published in December 2002

Adiponectin as an Independent Predictor of the Presence and Degree of Hepatic Steatosis in the Dallas Heart Study ⬇️

scientific article published on March 21, 2012

Adiponectin decreases pulmonary arterial remodeling in murine models of pulmonary hypertension.

scientific article

Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies

scientific article published on 07 April 2009

Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.

scientific article

Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity ⬇️

scientific article published on July 9, 2012

Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration

scientific article

Adiponectin levels and genotype: a potential regulator of life span in humans

scientific article

Adiponectin modulates ventral tegmental area dopamine neuron activity and anxiety-related behavior through AdipoR1.

scientific article published on 9 July 2018

Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons

scientific article published on 18 August 2016

Adiponectin promotes functional recovery after podocyte ablation

scientific article published on 18 January 2013

Adiponectin protects against incident hypertension independent of body fat distribution: observations from the Dallas Heart Study.

scientific article published on 25 July 2016

Adiponectin resistance exacerbates insulin resistance in insulin receptor transgenic/knockout mice

scientific article published on 02 May 2007

Adiponectin suppresses gluconeogenic gene expression in mouse hepatocytes independent of LKB1-AMPK signaling

scientific article

Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis through Adipose Tissue Crosstalk.

scientific article published on May 2016

Adiponectin, an adipocyte-derived hepatic insulin sensitizer regulation during development.

scientific article

Adiponectin, cardiovascular function, and hypertension

scientific article published on 12 November 2007

Adiponectin, driver or passenger on the road to insulin sensitivity?

scientific article

Adiponectin, the past two decades

scientific article published on 18 March 2016

Adiponectin-SOGA Dissociation in Type 1 Diabetes.

scientific article published on 8 June 2015

Adiponectin-mediated antilipotoxic effects in regenerating pancreatic islets

scientific article published on 27 March 2015

Adiponectin/Acrp30, an adipocyte-specific secretory factor: physiological relevance during development

scientific article published on March 2003

Adiponectin: Just Along for the Ride?

scientific article published on July 2016

Adiponectin: basic and clinical aspects. Preface

scientific article published on 21 November 2013

Adiponectin: no longer the lone soul in the fight against insulin resistance?

scientific article published on 01 December 2008

Adiponectin: systemic contributor to insulin sensitivity

scientific article

Adipose HIF-1α causes obesity by suppressing brown adipose tissue thermogenesis

scientific article published on 14 October 2016

Adipose Tissue: A Safe Haven for Parasites?

scientific article published on 19 December 2016

Adipose tissue biology and cardiomyopathy: translational implications

scientific article

Adipose tissue biology in 2014: Advances in our understanding of adipose tissue homeostasis

scientific article published on 16 December 2014

Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance

scientific article published on 17 December 2015

Adipose tissue remodeling and obesity

scientific article

Adipose tissue, diabetes and Chagas disease

scientific article

Adipose tissue, inflammation, and cardiovascular disease

scientific article

Adipose tissue-derived factors: impact on health and disease

scientific article published on 20 October 2006

Adipose tissue: The dysfunctional adipocyte - a cancer cell's best friend.

scientific article published on 5 January 2018

Adipose tissue: from lipid storage compartment to endocrine organ

scientific article

Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production

scientific article

Alterations in glucose homeostasis in a murine model of Chagas disease.

scientific article published on 12 January 2013

Alterations in pancreatic β cell function and Trypanosoma cruzi infection: evidence from human and animal studies

scientific article published on 24 December 2016

Altered Mitochondrial Function and Metabolic Inflexibility Associated with Loss of Caveolin-1 ⬇️

scientific article published on February 8, 2012

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents.

scientific article published in January 2018

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

scientific article published on 04 October 2018

An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

scientific article published on May 2013

An adipo-biliary-uridine axis that regulates energy homeostasis

scientific article published on 16 March 2017

Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2

scientific article published on 13 February 2007

Analytical validation and biological evaluation of a high molecular-weight adiponectin ELISA.

scientific article published on 19 October 2007

Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis

scientific article

Apoptosis through targeted activation of caspase 8 ("ATTAC-mice"): novel mouse models of inducible and reversible tissue ablation

scientific article published on 11 September 2005

Are dermal adipocytes involved in psoriasis?

scientific article published on 18 May 2016

Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women ⬇️

scientific article published on March 1, 2013

Autonomous interconversion between adult pancreatic α-cells and β-cells after differential metabolic challenges

scientific article published on 10 May 2016

Beclin 2 functions in autophagy, degradation of G protein-coupled receptors, and metabolism

scientific article

Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication

scientific article published on 17 June 2019

Brain adipocytokine action and metabolic regulation.

scientific article published on December 2006

Brown adipose tissue derived VEGF-A modulates cold tolerance and energy expenditure

scientific article

C/EBPalpha and the corepressors CtBP1 and CtBP2 regulate repression of select visceral white adipose genes during induction of the brown phenotype in white adipocytes by peroxisome proliferator-activated receptor gamma agonists

scientific article published on 29 June 2009

Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts

scientific article

Caveolin-1 as a pathophysiological factor and target in psoriasis

scientific article published on 05 February 2019

Caveolin-1 as a possible target in the treatment for acne

scientific article published on 09 December 2019

Caveolin-1 as a target in prevention and treatment of hypertrophic scarring

scientific article published on 26 April 2019

Caveolin-1 expression is essential for proper nonshivering thermogenesis in brown adipose tissue

scientific article published in March 2005

Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion

scientific article published on 7 September 2004

Caveolin-1 in skin aging - From innocent bystander to major contributor

scientific article published on 04 September 2019

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

scientific article published on 5 December 2001

Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue

scientific article published on 26 March 2003

Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle

scientific article published on 2 February 2005

Cell Biology. Ronning after the adiponectin receptors

scientific article

Cell type-specific expression and coregulation of murine resistin and resistin-like molecule-alpha in adipose tissue

scientific article published on August 2002

Cellular Origins of Beige Fat Cells Revisited

scientific article published on 01 October 2019

Ceramides and cardiac function in children with chronic kidney disease.

scientific article

Chagas disease, adipose tissue and the metabolic syndrome

scientific article published on July 2009

Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4 ⬇️

scientific article published on July 15, 2013

Circulating Adipokines and Inflammatory Markers and Postmenopausal Breast Cancer Risk

scientific article

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia

scientific article published on 25 March 2004

Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity

scientific article published on 29 December 2003

Compromised responses to dietary methionine restriction in adipose tissue but not liver of ob/ob mice

scientific article published on 3 August 2015

Conditional MitoTimer reporter mice for assessment of mitochondrial structure, oxidative stress, and mitophagy

scientific article published on 20 December 2017

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.

scientific article

Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette

scientific article

Consuming fructose-sweetened beverages increases body adiposity in mice.

scientific article published in July 2005

Contributions of adipose tissue architectural and tensile properties toward defining healthy and unhealthy obesity.

scientific article published on 03 December 2013

Correction to: The role of fat on cardiomyopathy outcome in mouse models of chronic Trypanosoma cruzi infection

scientific article published on 20 April 2020

Critical Role of Matrix Metalloproteinase 14 in Adipose Tissue Remodeling during Obesity

scientific article published on 30 March 2020

Critical lipids link breastfeeding to healthy adipose tissue in infancy and adulthood

scientific article published on 13 May 2019

Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection

scientific article

Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis.

scientific article

Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation

scientific article

Cyclin and caveolin expression in an acute model of murine Chagasic myocarditis

scientific article

Dapagliflozin suppresses glucagon signaling in rodent models of diabetes

scientific article published on 5 June 2017

Dermal Adipocytes: From Irrelevance to Metabolic Targets?

scientific article

Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot?

scientific article published on 19 January 2016

Dermal adipocytes contribute to the metabolic regulation of dermal fibroblasts

scientific article published on 31 August 2020

Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice

scientific article published on 01 December 2019

Diabetes and apoptosis: lipotoxicity

scientific article published on December 2009

Dichotomous effects of VEGF-A on adipose tissue dysfunction.

scientific article published on 26 March 2012

Dichotomous roles of leptin and adiponectin as enforcers against lipotoxicity during feast and famine

scientific article published on October 2013

Dietary n-3 polyunsaturated fatty acids fail to reduce prostate tumorigenesis in the PB-ErbB-2 x Pten(+/-) preclinical mouse model

scientific article published on 15 May 2010

Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis

scientific article published on 16 April 2018

Differential transendothelial transport of adiponectin complexes.

scientific article published on 20 February 2014

Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility

scientific article

Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation.

scientific article

Disulfide-dependent multimeric assembly of resistin family hormones

scientific article

DsbA-L is a versatile player in adiponectin secretion

scholarly article

Dysregulation of Amyloid Precursor Protein Impairs Adipose Tissue Mitochondrial Function and Promotes Obesity

scientific article published on 13 December 2019

E4orf1 induction in adipose tissue promotes insulin-independent signaling in the adipocyte

scientific article

ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue

scientific article

Effect of pioglitazone on plasma ceramides in adults with metabolic syndrome.

scientific article published on 10 May 2015

Effects of adiponectin on calcium-handling proteins in heart failure with preserved ejection fraction

scientific article

Elevated adiponectin prevents HIV protease inhibitor toxicity and preserves cerebrovascular homeostasis in mice.

scientific article

Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice

scientific article

Endothelin in a murine model of cerebral malaria

scientific article published in June 2006

Endotrophin - a novel factor linking obesity with aggressive tumor growth

scientific article published in December 2012

Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction

scientific article

Endotrophin, a multifaceted player in metabolic dysregulation and cancer progression, is a predictive biomarker for the response to PPARγ agonist treatment.

scientific article

Enhanced fatty acid flux triggered by adiponectin overexpression

scientific article published on November 2011

Enhanced metabolic flexibility associated with elevated adiponectin levels

scientific article

Erratum: Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance

scientific article published on 30 March 2016

Evidence for Trypanosoma cruzi in adipose tissue in human chronic Chagas disease.

scientific article published on 21 June 2011

Evidence for enhanced adipogenesis in the orbits of patients with Graves' ophthalmopathy

scientific article published on February 2004

Evolutionarily conserved role of calcineurin in phosphodegron-dependent degradation of phosphodiesterase 4D

scientific article

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

scientific article

Fabp4, a new player in the adipo-pancreatic axis

scientific article

Fasting selectively blocks development of acute lymphoblastic leukemia via leptin-receptor upregulation.

scientific article published on 12 December 2016

Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy

scientific article published on 19 June 2005

Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance ⬇️

scientific article published on July 17, 2012

Fat-cell mass, serum leptin and adiponectin changes during weight gain and loss in yellow-bellied marmots (Marmota flaviventris).

scientific article published on 29 October 2004

Fibrosis and Adipose Tissue Dysfunction ⬇️

scientific article published on August 15, 2013

Fibrosis-streaks and splatters: Some things are not always what they seem to be.

scientific article published on March 2016

Gender differences in adiponectin modulation of cardiac remodeling in mice deficient in endothelial nitric oxide synthase ⬇️

scientific article published on October 1, 2012

General theory of skin reinforcement.

scientific article published on 10 August 2017

Glucagon therapeutics, dawn of a new era for diabetes care.

scientific article published on 04 January 2016

Glucose-regulated protein 78 is essential for cardiac myocyte survival.

scientific article published on 17 April 2018

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

scientific article published on 10 March 2010

Golgi-localized PAQR4 mediates Anti-apoptotic Ceramidase Activity in Breast Cancer

scientific article published on 14 April 2020

Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1.

scientific article

HDAC11 suppresses the thermogenic program of adipose tissue via BRD2

scientific article published on 09 August 2018

Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue

scientific article published in January 2016

Hepatocyte Toll-like receptor 4 regulates obesity-induced inflammation and insulin resistance

scientific article

Hepatocyte growth factor and the risk of ischemic stroke developing among postmenopausal women: results from the Women's Health Initiative

scientific article published on 04 March 2010

Hepatocyte toll-like receptor 4 deficiency protects against alcohol-induced fatty liver disease.

scientific article published on 23 May 2018

High fat diet modulates Trypanosoma cruzi infection associated myocarditis

scientific article

High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice

scientific article published on 01 March 2019

Human Beige Adipocytes: Epiphenomenon or Drivers of Metabolic Improvements?

scientific article published on 31 March 2016

Human endotrophin as a driver of malignant tumor growth.

scientific article published on 21 March 2019

Hyaluronan in adipogenesis, adipose tissue physiology and systemic metabolism

scientific article published on 16 February 2018

Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier

scientific article published on 27 January 2016

Hyperglycemia in rodent models of type 2 diabetes requires insulin-resistant alpha cells

scientific article

Hypothalamic resistin induces hepatic insulin resistance

scientific article published on 24 May 2007

Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

scientific article published on 22 June 2009

Identification and characterization of a promoter cassette conferring adipocyte-specific gene expression

scientific article

Imaging Metabolically Active Fat: A Literature Review and Mechanistic Insights ⬇️

scientific article published on 05 November 2019

Immunologic and endocrine functions of adipose tissue: implications for kidney disease

scientific article published on 4 December 2017

Impact of simvastatin on adipose tissue: pleiotropic effects in vivo

scientific article published on 09 October 2009

Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase

scientific article

Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1.

scientific article

Improved methodologies for the study of adipose biology: insights gained and opportunities ahead

scientific article published on 16 February 2014

Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis

scientific article published on 12 January 2017

Induction of Effective Immunity against Trypanosoma cruzi

scientific article published on 23 March 2020

Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization

scientific article published on March 2002

Inflammation and ER stress regulate branched-chain amino acid uptake and metabolism in adipocytes

scientific article

Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours ⬇️

scientific article published on April 30, 2013

Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle

scientific article published on 9 January 2007

Intermittent hypoxia exacerbates pancreatic β-cell dysfunction in a mouse model of diabetes mellitus

scientific article published on December 2013

Intracellular lipid metabolism impairs β cell compensation during diet-induced obesity

scientific article published on 19 February 2018

Intracellular trafficking and secretion of adiponectin is dependent on GGA-coated vesicles

scientific article

Isolation and quantitation of adiponectin higher order complexes.

scientific article

Keynote review: the adipocyte as a drug discovery target

scientific article

Keystone meeting summary: 'Adipogenesis, obesity, and inflammation' and 'Diabetes mellitus and the control of cellular energy metabolism, ' January 21-26, 2006, Vancouver, Canada

scientific article published on 01 August 2006

Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

scientific article published on 23 December 2019

Lack of "immunological fitness" during fasting in metabolically challenged animals

scientific article

Lack of association between adiponectin levels and atherosclerosis in mice

scientific article

Leptin beyond the lipostat: key component of blood pressure regulation

scientific article

Leptin receptor signaling supports cancer cell metabolism through suppression of mitochondrial respiration in vivo

scientific article

Leptin: Less Is More

scientific article published on 01 May 2020

Lipid homeostasis, lipotoxicity and the metabolic syndrome.

scientific article

Lipid metabolism and adipokine levels in fatty acid-binding protein null and transgenic mice

scientific article

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

scientific article

Lipotoxicity and Cell Maintenance in Obesity and Type 2 Diabetes

scientific article published on 04 February 2019

Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction

scientific article published on 11 June 2018

Loss of resistin improves glucose homeostasis in leptin deficiency

scientific article

Loss of the liver X receptor LXRα/β in peripheral sensory neurons modifies energy expenditure.

scientific article published on 15 June 2015

Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue

scientific article published on 01 January 2020

Lowering ceramides to overcome diabetes

scientific article published on 01 July 2019

MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver

scientific article

MKR mice are resistant to the metabolic actions of both insulin and adiponectin: discordance between insulin resistance and adiponectin responsiveness.

scientific article published on 28 February 2006

Markers of oxidative stress in adipose tissue during Trypanosoma cruzi infection

scientific article

Maternal adiponectin controls milk composition to prevent neonatal inflammation

scientific article

Mechanisms of Trypanosoma cruzi persistence in Chagas disease

scientific article

Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes

scientific article

Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue

scientific article published on 15 September 2009

Mechanisms regulating repression of haptoglobin production by peroxisome proliferator-activated receptor-gamma ligands in adipocytes

scientific article

Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia

scientific article published on 8 June 2014

Metabolic Messengers: Adiponectin

scientific article published on 14 March 2019

Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.

scientific article published on 29 December 2008

Metabolic jet lag when the fat clock is out of sync

scientific article published in December 2012

Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists

scientific article

Minireview: The adipocyte--at the crossroads of energy homeostasis, inflammation, and atherosclerosis

scientific article

MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk

scientific article published on 19 February 2016

MitoNEET-dependent formation of intermitochondrial junctions.

scientific article

MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.

scientific article published on 09 September 2012

MitoNEET-mediated effects on browning of white adipose tissue

scientific article

Mitochondrial dysfunction in white adipose tissue ⬇️

scientific article published on July 10, 2012

Molecular cloning and developmental expression of the caveolin gene family in the amphibian Xenopus laevis

scientific article

Morphogenesis of the developing mammary gland: stage-dependent impact of adipocytes.

scientific article

Mouse Models of Lipodystrophy Key reagents for the understanding of the metabolic syndrome

scientific article published on January 2007

Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action.

scientific article published on 27 June 2005

Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors

scientific article published on April 2015

Nav1.8 neurons are involved in limiting acute phase responses to dietary fat.

scientific article published on 4 August 2017

Neuregulin 1-HER axis as a key mediator of hyperglycemic memory effects in breast cancer ⬇️

scientific article published on December 3, 2012

Neuroendocrine and Endocrine Pathways of Obesity ⬇️

scientific article published on September 19, 2012

New zoning laws enforced by glucagon

scientific article published on 9 April 2018

Obese adipocytes show ultrastructural features of stressed cells and die of pyroptosis.

scientific article published on 08 July 2013

Obese mice lacking inducible nitric oxide synthase are sensitized to the metabolic actions of peroxisome proliferator-activated receptor-gamma agonism.

scientific article published on 5 May 2008

Obesity and cancer--mechanisms underlying tumour progression and recurrence

scientific article

Obesity and diabetes as comorbidities for COVID-19: Underlying mechanisms and the role of viral-bacterial interactions

scientific article published on 15 September 2020

Obesity dysregulates fasting-induced changes in glucagon secretion

scientific article published on 01 November 2019

Obesity, Diabetes, and Cardiovascular Diseases: A Compendium

scientific article

Obesity-associated improvements in metabolic profile through expansion of adipose tissue

scientific article

Obesity: Slim without the gym--the magic of chilling out

scientific article published on 26 February 2016

Optimization of protein production in mammalian cells with a coexpressed fluorescent marker

scientific article

PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation

scientific article published on 9 May 2008

PAQRs: a counteracting force to ceramides?

scientific article published on 21 January 2009

PHOSPHO1 puts the breaks on thermogenesis in brown adipocytes

scientific article published on 08 July 2020

PPARγ and its Role in Adipocyte Homeostasis and Thiazolidinedione-Mediated Insulin Sensitization.

scientific article published on 26 February 2018

PPARγ in vagal neurons regulates high-fat diet induced thermogenesis

scientific journal article

Paracrine and Endocrine Effects of Adipose Tissue on Cancer Development and Progression ⬇️

scientific article published on June 2, 2011

Paradoxical elevation of high-molecular weight adiponectin in acquired extreme insulin resistance due to insulin receptor antibodies

scientific article

Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy

scientific article published on 05 September 2019

Partial leptin deficiency confers resistance to diet-induced obesity in mice

scientific article published on 11 April 2020

Pas de Deux: Glucagon and Thyroid Hormone Moving in Perfect Synchrony

scientific article published on March 2017

Pathological Type-2 Immune Response, Enhanced Tumor Growth, and Glucose Intolerance in Retnlβ (RELMβ) Null Mice: A Model of Intestinal Immune System Dysfunction in Disease Susceptibility.

scientific article published on 7 July 2016

Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein

scientific article published on 15 December 2006

Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome

scientific article published on 26 July 2009

Phenotypic behavior of caveolin-3 R26Q, a mutant associated with hyperCKemia, distal myopathy, and rippling muscle disease

scientific article published on 2 July 2003

Phenotypical Conversions of Dermal Adipocytes as Pathophysiological Steps in Inflammatory Cutaneous Disorders

scientific article published in 2022

Phosphofructokinase muscle-specific isoform requires caveolin-3 expression for plasma membrane recruitment and caveolar targeting: implications for the pathogenesis of caveolin-related muscle diseases

scientific article published in December 2003

Plasma adiponectin complexes have distinct biochemical characteristics

scientific article published on 17 January 2008

Plasma ceramides are elevated in female children and adolescents with type 2 diabetes

scientific article

Proangiogenic contribution of adiponectin toward mammary tumor growth in vivo

scientific article published on 15 May 2009

Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes

scientific article published in March 2007

Proteinuria Increases Plasma Phosphate by Altering Its Tubular Handling

scientific article published on 27 October 2014

Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification

scientific article published in 2022

Race-ethnic differences in adipokine levels: the Study of Women's Health Across the Nation (SWAN).

scientific article

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

scientific article

Regulation of resistin expression and circulating levels in obesity, diabetes, and fasting

scientific article

Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study

scientific article published on 29 August 2018

Relationship between Changes in Plasma Adiponectin Concentration and Insulin Sensitivity after Niacin Therapy

scientific article

Remodeling of Murine Mammary Adipose Tissue during Pregnancy, Lactation, and Involution

scientific article published on 12 September 2019

Renal tubular cell spliced X-box binding protein 1 (Xbp1s) has a unique role in sepsis-induced acute kidney injury and inflammation

scientific article published on 01 August 2019

Resistin, but not adiponectin and leptin, is associated with the risk of ischemic stroke among postmenopausal women: results from the Women's Health Initiative

scientific article

Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain).

scientific article published on 31 January 2012

Retrograde Lymph Flow Leads to Chylothorax in Transgenic Mice with Lymphatic Malformations

scientific article published on 3 July 2017

Reversible De-differentiation of Mature White Adipocytes into Preadipocyte-like Precursors during Lactation

scientific article published on 14 June 2018

Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes

scientific article

Role of caveolin and caveolae in insulin signaling and diabetes ⬇️

scientific article published on December 1, 2003

Role of caveolin-1 in the modulation of lipolysis and lipid droplet formation

scientific article published in May 2004

Role of ceramide-to-dihydroceramide ratios for insulin resistance and non-alcoholic fatty liver disease in humans

scientific article published on 01 November 2020

Role of extracellular signal-regulated kinase 5 in adipocyte signaling

scientific article published on 14 January 2014

Role of resistin in diet-induced hepatic insulin resistance

scientific article

Role of transcription factor NFAT in glucose and insulin homeostasis

scientific article

SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise

scientific article

SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1

scientific article published on 16 July 2019

Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention.

scientific article published on 12 March 2007

Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects

scientific article

Selective enhancement of insulin sensitivity in the mature adipocyte is sufficient for systemic metabolic improvements

scientific article published on 5 August 2015

Selective inhibition of hypoxia-inducible factor 1α ameliorates adipose tissue dysfunction.

scientific article

Serum Amyloid A3 Gene Expression in Adipocytes is an Indicator of the Interaction with Macrophages

scientific article published on 08 December 2016

Serum adiponectin complexes and cardiovascular risk in children with chronic kidney disease ⬇️

scientific article published on May 8, 2011

Serum adiponectin is related to plasma high-density lipoprotein cholesterol but not to plasma insulin-concentration in healthy children: the FLVS II study

scientific article

Sexual differentiation, pregnancy, calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin

scientific article published on February 2003

Short-Term Versus Long-Term Effects of Adipocyte Toll-Like Receptor 4 Activation on Insulin Resistance in Male Mice

scientific article published on 24 February 2017

Skin aging: are adipocytes the next target?

scientific article published on 18 July 2016

Spliced X-box Binding Protein 1 Stimulates Adaptive Growth Through Activation of mTOR

scientific article published on 10 June 2019

Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway

scientific article published on March 2014

Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1

scientific article

Structure-function studies of the adipocyte-secreted hormone Acrp30/adiponectin. Implications fpr metabolic regulation and bioactivity

scientific article published on 20 December 2002

Structure-guided Development of Specific Pyruvate Dehydrogenase Kinase Inhibitors Targeting the ATP-binding Pocket

scientific article

Systemic fate of the adipocyte-derived factor adiponectin

scientific article published on 06 July 2009

Targeted Induction of Ceramide Degradation Leads to Improved Systemic Metabolism and Reduced Hepatic Steatosis

scientific article

Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages

scientific article

Targeting adipose tissue in the treatment of obesity-associated diabetes

scientific article published on 3 June 2016

Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion

scientific article published on 16 February 2016

The AdipoChaser mouse: A model tracking adipogenesis in vivo.

scientific article published on 14 January 2014

The MMP14-caveolin axis and its potential relevance for lipoedema

scientific article published on 13 August 2020

The Multifaceted Roles of Adipose Tissue-Therapeutic Targets for Diabetes and Beyond: The 2015 Banting Lecture

scientific article published on June 2016

The PPARγ-FGF1 axis: an unexpected mediator of adipose tissue homeostasis.

scientific article published on 19 June 2012

The Role of Immature and Mature Adipocytes in Hair Cycling

scientific article published on 14 December 2018

The Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Nephrotic Syndrome-Associated Hypercholesterolemia

scientific article published on July 2016

The Xbp1s/GalE axis links ER stress to postprandial hepatic metabolism ⬇️

scientific article published on December 21, 2012

The adipocyte as an endocrine cell

scientific article published on 01 September 2008

The adipocyte as an important target cell for Trypanosoma cruzi infection

scientific article published on 18 April 2005

The adipokine SAA3 is induced by interleukin-1beta in mouse adipocytes

scientific article published on August 2008

The adipokine/ceramide axis: key aspects of insulin sensitization

scientific article

The cell biology of fat expansion

scientific article

The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation

scientific article published on June 2004

The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species

scientific article published on 9 November 2004

The impact of endotrophin on the progression of chronic liver disease

scientific article published on 27 October 2020

The many secret lives of adipocytes: implications for diabetes

scientific article published on 21 November 2018

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

scientific article published on 3 January 2017

The role of adipocytes and adipocyte-like cells in the severity of COVID-19 infections

scientific article published on 27 April 2020

The transcriptional response of the islet to pregnancy in mice

scientific article published on 02 July 2009

Thromboxane A2 is a key regulator of pathogenesis during Trypanosoma cruzi infection

scientific article

Thromboxane A2is a key regulator of pathogenesis duringTrypanosoma cruziinfection

Tissue-specific disruption of Kbtbd2 uncovers adipocyte-intrinsic and -extrinsic features of the teeny lipodystrophy syndrome

scientific article published on 07 May 2020

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

scientific article

Trypanosoma cruzi infection of cultured adipocytes results in an inflammatory phenotype

scientific article published on September 2008

Trypanosoma cruzi utilizes the host low density lipoprotein receptor in invasion. ⬇️

scientific article

Utility of Adipocyte Fractions in Fat Grafting in an Athymic Rat Model

scientific article published on 01 November 2018

VEGF-A-Expressing Adipose Tissue Shows Rapid Beiging and Enhanced Survival After Transplantation and Confers IL-4-Independent Metabolic Improvements.

scientific article published on 2 March 2017

Vascular Endothelial Growth Factor-D (VEGF-D) Overexpression and Lymphatic Expansion in Murine Adipose Tissue Improves Metabolism in Obesity

scientific article published on 13 March 2019

Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans

scientific article published on 07 February 2007

Within-individual stability of obesity-related biomarkers among women

scientific article published on June 2007

XBP1S Regulates MUC5B in a Promoter Variant-Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia

scientific article published on 01 July 2019

Xbp1s in Pomc neurons connects ER stress with energy balance and glucose homeostasis.

scientific article

microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism

scientific article published on 16 February 2017

β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis

scientific article published on 14 January 2019

Paulina is supported by:

About Paulina

Help