List of works by Pascal Meier

A tangled web of ubiquitin chains: breaking news in TNF-R1 signaling.

scientific article published on December 2009

Alternative mRNAs encode multiple isoforms of transcription factor AP-2 during murine embryogenesis.

scientific article published on May 1995

An inhibitory mono-ubiquitylation of the Drosophila initiator caspase Dronc functions in both apoptotic and non-apoptotic pathways

scientific article

Analysis of Apoptosis and Necroptosis by Fluorescence-Activated Cell Sorting

scientific article

Apoptosis in development

scientific article published in Nature

CARD-mediated autoinhibition of cIAP1's E3 ligase activity suppresses cell proliferation and migration

scientific article

Caspase-10 Negatively Regulates Caspase-8-Mediated Cell Death, Switching the Response to CD95L in Favor of NF-κB Activation and Cell Survival

scientific article published on April 2017

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling

scientific article published on January 2010

Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer

scientific article published on 4 December 2017

DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells

scientific article published on December 2007

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

scientific article published in May 2003

Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation

scientific article

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer

scientific article published on 01 April 2017

Erratum: PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

scientific article

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

scientific article

IAP degradation: decisive blow or altruistic sacrifice?

scientific article published on 01 October 2002

IAP-antagonists exhibit non-redundant modes of action through differential DIAP1 binding

scientific article published on December 2003

IAPs are functionally non-equivalent and regulate effector caspases through distinct mechanisms

scientific article published on 5 December 2004

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

scientific article published on 19 October 2008

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

scientific article

IAPs: guardians of RIPK1

scientific article

Identification and Characterization of Novel Receptor-Interacting Serine/Threonine-Protein Kinase 2 Inhibitors Using Structural Similarity Analysis.

scientific article published on 19 March 2018

Inactivation of effector caspases through nondegradative polyubiquitylation

scientific article

Inhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammation

scientific article

Inhibitor of apoptosis proteins in Drosophila: gatekeepers of death

scientific article published on 03 June 2009

Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1

scientific article published on October 2002

Lucifer's labyrinth--ten years of path finding in cell death

scientific article published on December 2007

MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death

scientific article

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential.

scientific article published in April 2018

Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2.

scientific article published on 18 February 2011

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

scientific article

PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer.

scientific article published on 24 October 2016

PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling

scientific article published on August 2008

Programmed cell death: Superman meets Dr Death

scientific article

RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements

scientific article published on December 2016

RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation

scientific article published on 28 December 2018

RIPK1-mediated immunogenic cell death promotes anti-tumour immunity against soft-tissue sarcoma

scientific article published on 18 May 2020

Ripk1 and haematopoiesis: a case for LUBAC and Ripk3.

scientific article published in August 2018

SUMO-mediated regulation of NLRP3 modulates inflammasome activity

scientific article published in Nature Communications

Signal Integration by the IκB Protein Pickle Shapes Drosophila Innate Host Defense

scientific article published on September 2016

Systematic in vivo RNAi analysis identifies IAPs as NEDD8-E3 ligases

scientific article published in December 2010

The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis

scientific article published in June 2002

The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection

scientific article published on 7 August 2006

The NMDA receptor regulates competition of epithelial cells in the Drosophila wing

scientific article published on 06 May 2020

The Ripoptosome, a signaling platform that assembles in response to genotoxic stress and loss of IAPs

scientific article published on 7 July 2011

The anticonvulsive Phenhydan® suppresses extrinsic cell death

scientific article published on 15 November 2018

The regulatory isoform rPGRP-LC induces immune resolution via endosomal degradation of receptors

scientific article published on 22 August 2016

The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles

scientific article published on 10 March 2016

Time-Lapse Imaging of Cell Death

scientific article published on March 2016

Time-lapse imaging of necrosis

scientific article published on January 2013

Tissue Repair: How to Inflame Your Neighbours

scientific article published in March 2016

To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and death

scientific article

Transcription factor AP-2 essential for cranial closure and craniofacial development

scientific journal article

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

scholarly article

Ubiquitin-Mediated Regulation of Cell Death, Inflammation, and Defense of Homeostasis

scientific article

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2.

scientific article published in February 2018

Ubiquitin-mediated regulation of RhoGTPase signalling: IAPs and HACE1 enter the fray

scientific article published on 4 January 2012

Ubiquitin-mediated regulation of apoptosis

scientific article published on 13 February 2009

Ubiquitylation in apoptosis: DIAP1's (N-)en(d)igma

scientific article published on 01 September 2005

Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance

scientific article published on 07 June 2021

Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling.

scientific article published on May 2012

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