List of works - Roger Paredes

Added Value of Deep Sequencing Relative to Population Sequencing in Heavily Pre-Treated HIV-1-Infected Subjects ⬇️

scientific article published on May 13, 2011

Alternation of antiretroviral drug regimens for HIV infection. Efficacy, safety and tolerability at week 96 of the Swatch Study

scientific article published in December 2004

Antiretroviral simplification with darunavir/ritonavir monotherapy in routine clinical practice: safety, effectiveness, and impact on lipid profile

scientific article (publication date: 2012)

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes

scientific article published on 16 July 2016

Balances: a New Perspective for Microbiome Analysis

scientific article published on 17 July 2018

Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection

scientific article published on 24 January 2022

Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control study

article

Compromised immunologic recovery in treatment-experienced patients with HIV infection receiving both tenofovir disoproxil fumarate and didanosine in the TORO studies

scientific article published on 15 August 2005

Connection Domain Mutations in HIV-1 Reverse Transcriptase Do Not Impact Etravirine Susceptibility and Virologic Responses to Etravirine-Containing Regimens ⬇️

scientific article published on April 4, 2011

Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection

scientific article

Decreased phenotypic susceptibility to etravirine in patients with predicted genotypic sensitivity

scientific article (publication date: 2014)

Deep molecular characterization of HIV-1 dynamics under suppressive HAART

scientific article

Dolutegravir-based maintenance monotherapy versus dual therapy with lamivudine: a planned 24 week analysis of the DOLAM randomized clinical trial

scientific article published on 01 July 2018

Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure

scientific article published on 29 September 2010

Effect of an induction period of pegylated interferon-α2a and ribavirin on early virological response in HIV-HCV-coinfected patients: results from the CORAL-2 study

scientific article published in January 2011

Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study

scientific article published on 25 February 2011

Effectiveness of a Treatment Switch to Nevirapine plus Tenofovir and Emtricitabine (or Lamivudine) in Adults with HIV-1 Suppressed Viremia

scientific article

European recommendations for the clinical use of HIV drug resistance testing: 2011 update

scientific article published on April 1, 2011

Global Dispersal Pattern of HIV Type 1 Subtype CRF01_AE: A Genetic Trace of Human Mobility Related to Heterosexual Sexual Activities Centralized in Southeast Asia

scientific article published on 15 December 2014

Gut Microbiota Linked to Sexual Preference and HIV Infection.

scientific article

Gut microbiome comparability of fresh-frozen versus stabilized-frozen samples from hospitalized patients using 16S rRNA gene and shotgun metagenomic sequencing

scientific article published on 16 September 2019

HIV-1 infection in subjects older than 70: a multicenter cross-sectional assessment in Catalonia, Spain

scientific article published in November 2009

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

scientific article published on 14 January 2013

HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization

scientific article

HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.

scientific article published on 28 June 2012

Highly pathogenic adapted HIV-1 strains limit host immunity and dictate rapid disease progression

scientific article published on June 2014

Incidence of post-acute COVID-19 symptoms across healthcare settings in seven countries: an international retrospective cohort study using routinely-collected data

scientific article published in 2024

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

scientific article

Increased peripheral proinflammatory cytokines in HIV-1-infected patients with prolonged viral suppression suffering from high psychological stress

scientific article published in November 2009

Limited cross-border infections in patients newly diagnosed with HIV in Europe

scientific article published on 3 April 2013

Long-Term Safety and Efficacy of Nevirapine-Based Approaches in HIV Type 1-Infected Patients

article

Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection

article

Low-abundance drug-resistant HIV-1 variants in antiretroviral drug-naïve individuals: A systematic review of detection methods, prevalence, and clinical impact

scientific article published on 06 December 2019

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing

scientific article

No detection of the NS5B S282T mutation in treatment-naïve genotype 1 HCV/HIV-1 coinfected patients using deep sequencing

scientific article published on 3 October 2013

Patterns of transmitted HIV drug resistance in Europe vary by risk group

scientific article (publication date: 2014)

Performance comparison of next generation sequencing analysis pipelines for HIV-1 drug resistance testing

scientific article published on 31 January 2020

Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy

scientific article

Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure

scientific article

Primary resistance to integrase strand transfer inhibitors in patients infected with diverse HIV-1 subtypes in sub-Saharan Africa.

scientific article published on 14 February 2018

Quality of life, emotional status, and adherence of HIV-1-infected patients treated with efavirenz versus protease inhibitor-containing regimens

scientific article

Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo

scientific article

Quebrada Jaguay: Early South American Maritime Adaptations ⬇️

scientific article published on September 18, 1998

Randomised study to assess the efficacy and safety of once-daily etravirine-based regimen as a switching strategy in HIV-infected patients receiving a protease inhibitor-containing regimen. Etraswitch study

scientific article

Randomized, crossover, double-blind, placebo-controlled trial to assess the lipid lowering effect of co-formulated TDF/FTC.

scientific article published on 2 November 2014

Relationship between minority nonnucleoside reverse transcriptase inhibitor resistance mutations, adherence, and the risk of virologic failure

scientific article

Reversal of HIV-1-associated osteoporosis with once-weekly alendronate

scientific article published in February 2005

Reversal of atherogenic lipoprotein profile in HIV-1 infected patients with lipodystrophy after replacing protease inhibitors by nevirapine

scientific article

Richer gut microbiota with distinct metabolic profile in HIV infected Elite Controllers

scientific article

Role of structured treatment interruption before a 5-drug salvage antiretroviral regimen: the Retrogene Study.

scientific article

Routine screening of anal cytology in HIV-infected subjects and the impact on invasive anal cancer. A prospective cohort study

scientific article published on 04 September 2019

Short Communication: Efficacy and Safety of Treatment Simplification to Lopinavir/Ritonavir or Darunavir/Ritonavir Monotherapy: A Randomized Clinical Trial

scientific article

Single oral dose of maraviroc does not prevent ex-vivo HIV infection of rectal mucosa in HIV-1 negative human volunteers

scientific article

Stable HIV-1 integrase diversity during initial HIV-1 RNA decay suggests complete blockade of plasma HIV-1 replication by effective raltegravir-containing salvage therapy

scientific article published on 05 December 2013

Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort

scientific article

Switching the third drug of antiretroviral therapy to maraviroc in aviraemic subjects: a pilot, prospective, randomized clinical trial

scientific article published on 25 January 2013

The burden of post-acute COVID-19 symptoms in a multinational network cohort analysis

scientific article published in 2023

The evolving landscape of HIV drug resistance diagnostics for expanding testing in resource-limited settings

scientific article

The global spread of HIV-1 subtype B epidemic

scientific article

The lipid-lowering effect of tenofovir/emtricitabine: a randomized, crossover, double-blind, placebo-controlled trial

scientific article published on 13 April 2015

Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe

scientific article published on 29 November 2015

Trends and predictors of transmitted drug resistance (TDR) and clusters with TDR in a local Belgian HIV-1 epidemic

scientific article (publication date: 2014)

Triple-class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years

scientific article published in March 2010

Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load

scientific article published in February 2004

Vicriviroc Resistance Decay and Relative Replicative Fitness in HIV-1 Clinical Isolates under Sequential Drug Selection Pressures ⬇️

scientific article published on April 4, 2012

Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppression

scientific article published on 2 January 2002

List of works by Roger Paredes

Added Value of Deep Sequencing Relative to Population Sequencing in Heavily Pre-Treated HIV-1-Infected Subjects ⬇️

Alternation of antiretroviral drug regimens for HIV infection. Efficacy, safety and tolerability at week 96 of the Swatch Study

Antiretroviral simplification with darunavir/ritonavir monotherapy in routine clinical practice: safety, effectiveness, and impact on lipid profile

Antiretroviral therapy suppressed participants with low CD4+ T-cell counts segregate according to opposite immunological phenotypes

Balances: a New Perspective for Microbiome Analysis

Clinical course impacts early kinetics,magnitude, and amplitude of SARS-CoV-2 neutralizing antibodies beyond 1 year after infection

Clinically relevant thresholds for ultrasensitive HIV drug resistance testing: a multi-country nested case-control study

Compromised immunologic recovery in treatment-experienced patients with HIV infection receiving both tenofovir disoproxil fumarate and didanosine in the TORO studies

Connection Domain Mutations in HIV-1 Reverse Transcriptase Do Not Impact Etravirine Susceptibility and Virologic Responses to Etravirine-Containing Regimens ⬇️

Contribution of immunological and virological factors to extremely severe primary HIV type 1 infection

Decreased phenotypic susceptibility to etravirine in patients with predicted genotypic sensitivity

Deep molecular characterization of HIV-1 dynamics under suppressive HAART

Dolutegravir-based maintenance monotherapy versus dual therapy with lamivudine: a planned 24 week analysis of the DOLAM randomized clinical trial

Dynamic escape of pre-existing raltegravir-resistant HIV-1 from raltegravir selection pressure

Effect of an induction period of pegylated interferon-α2a and ribavirin on early virological response in HIV-HCV-coinfected patients: results from the CORAL-2 study

Effect of transmitted drug resistance on virological and immunological response to initial combination antiretroviral therapy for HIV (EuroCoord-CHAIN joint project): a European multicohort study

Effectiveness of a Treatment Switch to Nevirapine plus Tenofovir and Emtricitabine (or Lamivudine) in Adults with HIV-1 Suppressed Viremia

European recommendations for the clinical use of HIV drug resistance testing: 2011 update

Global Dispersal Pattern of HIV Type 1 Subtype CRF01_AE: A Genetic Trace of Human Mobility Related to Heterosexual Sexual Activities Centralized in Southeast Asia

Gut Microbiota Linked to Sexual Preference and HIV Infection.

Gut microbiome comparability of fresh-frozen versus stabilized-frozen samples from hospitalized patients using 16S rRNA gene and shotgun metagenomic sequencing

HIV-1 infection in subjects older than 70: a multicenter cross-sectional assessment in Catalonia, Spain

HIV-1 subtype distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

HIV-1 tropism testing in subjects achieving undetectable HIV-1 RNA: diagnostic accuracy, viral evolution and compartmentalization

HLA class I protective alleles in an HIV-1-infected subject homozygous for CCR5-Δ32/Δ32.

Highly pathogenic adapted HIV-1 strains limit host immunity and dictate rapid disease progression

Incidence of post-acute COVID-19 symptoms across healthcare settings in seven countries: an international retrospective cohort study using routinely-collected data

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

Increased peripheral proinflammatory cytokines in HIV-1-infected patients with prolonged viral suppression suffering from high psychological stress

Limited cross-border infections in patients newly diagnosed with HIV in Europe

Long-Term Safety and Efficacy of Nevirapine-Based Approaches in HIV Type 1-Infected Patients

Low nadir CD4+ T-cell counts predict gut dysbiosis in HIV-1 infection

Low-abundance drug-resistant HIV-1 variants in antiretroviral drug-naïve individuals: A systematic review of detection methods, prevalence, and clinical impact

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing

No detection of the NS5B S282T mutation in treatment-naïve genotype 1 HCV/HIV-1 coinfected patients using deep sequencing

Patterns of transmitted HIV drug resistance in Europe vary by risk group

Performance comparison of next generation sequencing analysis pipelines for HIV-1 drug resistance testing

Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy

Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure

Primary resistance to integrase strand transfer inhibitors in patients infected with diverse HIV-1 subtypes in sub-Saharan Africa.

Quality of life, emotional status, and adherence of HIV-1-infected patients treated with efavirenz versus protease inhibitor-containing regimens

Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo

Quebrada Jaguay: Early South American Maritime Adaptations ⬇️

Randomised study to assess the efficacy and safety of once-daily etravirine-based regimen as a switching strategy in HIV-infected patients receiving a protease inhibitor-containing regimen. Etraswitch study

Randomized, crossover, double-blind, placebo-controlled trial to assess the lipid lowering effect of co-formulated TDF/FTC.

Relationship between minority nonnucleoside reverse transcriptase inhibitor resistance mutations, adherence, and the risk of virologic failure

Reversal of HIV-1-associated osteoporosis with once-weekly alendronate

Reversal of atherogenic lipoprotein profile in HIV-1 infected patients with lipodystrophy after replacing protease inhibitors by nevirapine

Richer gut microbiota with distinct metabolic profile in HIV infected Elite Controllers

Role of structured treatment interruption before a 5-drug salvage antiretroviral regimen: the Retrogene Study.

Routine screening of anal cytology in HIV-infected subjects and the impact on invasive anal cancer. A prospective cohort study

Short Communication: Efficacy and Safety of Treatment Simplification to Lopinavir/Ritonavir or Darunavir/Ritonavir Monotherapy: A Randomized Clinical Trial

Single oral dose of maraviroc does not prevent ex-vivo HIV infection of rectal mucosa in HIV-1 negative human volunteers

Stable HIV-1 integrase diversity during initial HIV-1 RNA decay suggests complete blockade of plasma HIV-1 replication by effective raltegravir-containing salvage therapy

Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort

Switching the third drug of antiretroviral therapy to maraviroc in aviraemic subjects: a pilot, prospective, randomized clinical trial

The burden of post-acute COVID-19 symptoms in a multinational network cohort analysis

The evolving landscape of HIV drug resistance diagnostics for expanding testing in resource-limited settings

The global spread of HIV-1 subtype B epidemic

The lipid-lowering effect of tenofovir/emtricitabine: a randomized, crossover, double-blind, placebo-controlled trial

Transmission of HIV Drug Resistance and the Predicted Effect on Current First-line Regimens in Europe

Trends and predictors of transmitted drug resistance (TDR) and clusters with TDR in a local Belgian HIV-1 epidemic

Triple-class virologic failure in HIV-infected patients undergoing antiretroviral therapy for up to 10 years

Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load

Vicriviroc Resistance Decay and Relative Replicative Fitness in HIV-1 Clinical Isolates under Sequential Drug Selection Pressures ⬇️

Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppression