Search filters

List of works by Janet Shipley

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

scientific article

ATR Is a Therapeutic Target in Synovial Sarcoma.

scientific article published on 16 October 2017

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma

article

Age-related biological features of germ cell tumors ⬇️

scientific article published on 05 December 2013

An additional human chromosome 21 causes suppression of neural fate of pluripotent mouse embryonic stem cells in a teratoma model

scientific article

Association between Large-scale Genomic Homozygosity without Chromosomal Loss and Nonseminomatous Germ Cell Tumor Development

article

Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk ⬇️

scientific article published on September 18, 1997

Characterization of a t(8;13)(p11;q11-12) in an atypical myeloproliferative disorder ⬇️

scientific article published on 01 January 1998

Chemosensitivity profiling of osteosarcoma tumour cell lines identifies a model of BRCAness

scientific article published on 13 July 2018

Chromosomal imbalances associated with carcinoma in situ and associated testicular germ cell tumours of adolescents and adults.

scientific article published in July 2001

Chromosome 1q expression profiling and relapse in Wilms' tumour

scientific article published on 01 August 2002

Chromosome translocations in sarcomas and the analysis of paraffin-embedded material

scientific article published on 01 January 1998

Clinical Application of Prognostic Gene Expression Signature in Fusion Gene-Negative Rhabdomyosarcoma: A Report from the Children's Oncology Group

scientific article

Clinical and biological significance of CXCL12 and CXCR4 expression in adult testes and germ cell tumours of adults and adolescents.

scientific article published on January 2009

Cloning and mapping of members of the MYM family

scientific article

Common variants identified in genome-wide association studies of testicular germ cell tumour: an update, biological insights and clinical application

scientific article

Comparative expressed sequence hybridization to chromosomes for tumor classification and identification of genomic regions of differential gene expression

scientific article

Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia ⬇️

scientific article published on October 15, 1998

Comparative genomic hybridization and BUB1B mutation analyses in childhood cancers associated with mosaic variegated aneuploidy syndrome

article

DYRK1A-dosage imbalance perturbs NRSF/REST levels, deregulating pluripotency and embryonic stem cell fate in Down syndrome

scientific article published on 4 September 2008

Defining a New Prognostic Index for Stage I Nonseminomatous Germ Cell Tumors Using CXCL12 Expression and Proportion of Embryonal Carcinoma.

scientific article published on 9 October 2015

Defining minimum genomic regions of imbalance involved in testicular germ cell tumors of adolescents and adults through genome wide microarray analysis of cDNA clones

scientific article published on 01 December 2004

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

scientific article published on 6 December 2017

Diagnosis of Ewing's sarcoma and related tumours by detection of chromosome 22q12 translocations using fluorescence in situ hybridization on tumour touch imprints ⬇️

scientific article published on June 1, 1995

Differential regulation of MAP kinase activation by a novel splice variant of human MAP kinase phosphatase-2.

scientific article published on March 2010

Distinct Genetic and Epigenetic Changes in Medullary Breast Cancer

scientific article published on 01 July 2003

Distinct comparative genomic hybridisation profiles in gastric mucosa-associated lymphoid tissue lymphomas with and without t(11;18)(q21;q21).

scientific article

Distinct effects of ligand-induced PDGFRα and PDGFRβ signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.

scientific article published on 21 January 2013

Distinct roles for miR-1 and miR-133a in the proliferation and differentiation of rhabdomyosarcoma cells

scientific article

Dual blockade of the PI3K/AKT/mTOR (AZD8055) and RAS/MEK/ERK (AZD6244) pathways synergistically inhibits rhabdomyosarcoma cell growth in vitro and in vivo.

scientific article published on 05 August 2013

Dual colour fluorescence in situ hybridization to paraffin-embedded samples to deduce the presence of the der(X)t(X;18)(p11.2;q11.2) and involvement of either the SSX1 or SSX2 gene: a diagnostic and prognostic aid for synovial sarcoma

scientific article published on 01 March 1999

Endosialin expression in soft tissue sarcoma as a potential marker of undifferentiated mesenchymal cells

scientific article published on 19 July 2016

Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer.

scientific article

Expression profiling targeting chromosomes for tumor classification and prediction of clinical behavior.

scientific article published on November 2003

Fluorescence In Situ Hybridization for Cancer-Related Studies ⬇️

scientific article published on January 1, 2012

Fluorescence in situ hybridization analysis of formalin fixed paraffin embedded tissues, including tissue microarrays.

scientific article

Fusion gene-negative alveolar rhabdomyosarcoma is clinically and molecularly indistinguishable from embryonal rhabdomyosarcoma.

scientific article published on 29 March 2010

Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma

scientific article

Fusion status in patients with lymph node-positive (N1) alveolar rhabdomyosarcoma is a powerful predictor of prognosis: Experience of the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG)

scientific article published on 24 May 2018

Gain of 1q is associated with adverse outcome in favorable histology Wilms' tumors

scientific article published on February 2001

Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene

scientific article

Genomic copy number and expression patterns in testicular germ cell tumours.

scientific article published on 4 December 2007

Genomic gain and over expression of CCL2 correlate with vascular invasion in stage I non-seminomatous testicular germ-cell tumours.

scientific article

Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: an approach to identify candidate genes involved in tumor development

scientific article

Glypican-3 is expressed in rhabdomyosarcomas but not adult spindle cell and pleomorphic sarcomas.

scientific article

HES6 enhances the motility of alveolar rhabdomyosarcoma cells.

scientific article

Hypoxia and its therapeutic possibilities in paediatric cancers

scientific article published on 27 October 2020

ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins.

scientific article

IGF1R signalling in testicular germ cell tumour cells impacts on cell survival and acquired cisplatin resistance

scientific article published on 21 November 2017

Identification of 19 new risk loci and potential regulatory mechanisms influencing susceptibility to testicular germ cell tumor ⬇️

scientific article published on 12 June 2017

Identification of ZDHHC14 as a novel human tumour suppressor gene.

scientific article published on 8 February 2014

Identification of four new susceptibility loci for testicular germ cell tumour ⬇️

scientific article published on 27 October 2015

Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14

scientific article published on 12 May 2013

Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma

scientific article (publication date: August 1994)

Immunohistochemical detection of glypican-5 in paraffin-embedded material: an optimized method for a novel research antibody.

scientific article

Impact of fusion gene status versus histology on risk-stratification for rhabdomyosarcoma: Retrospective analyses of patients on UK trials.

scientific article published on 30 December 2016

Inconvenience of convenience cohorts--letter.

scientific article published on 26 June 2012

Increased level of chromosomal damage after irradiation of lymphocytes from BRCA1 mutation carriers

scientific article published on January 2006

Interphase fluorescence in situ hybridization detection of t(2;13)(q35;q14) in alveolar rhabdomyosarcoma--a diagnostic tool in minimally invasive biopsies

scientific article published on 01 April 1996

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.

scientific article

KIT and RAS signalling pathways in testicular germ cell tumours: new data and a review of the literature.

scientific article

Less Can Be More for Gene Dose and Drug Sensitivity.

scientific article

Loss of 13q14-q21 and gain of 5p14-pter in the progression of leiomyosarcoma.

scientific article

Mapping of a translocation breakpoint in a Peutz-Jeghers hamartoma to the putative PJS locus at 19q13.4 and mutation analysis of candidate genes in polyp and STK11-negative PJS cases

scientific article

Mapping the X chromosome breakpoint in two papillary renal cell carcinoma cell lines with a t(X;1)(p11.2;q21.2) and the first report of a female case.

scientific article published on January 1995

MicroRNA and gene co-expression networks characterize biological and clinical behavior of rhabdomyosarcomas.

scientific article published on 28 October 2016

Minimum regions of genomic imbalance in stage I testicular embryonal carcinoma and association of 22q loss with relapse.

scientific article

Molecular characterisation of the t(1;15)(p22;q22) translocation in the prostate cancer cell line LNCaP.

scientific article

Molecular cytogenetic analysis consistently identifies translocations involving chromosomes 1, 2 and 15 in five embryonal rhabdomyosarcoma cell lines and a PAX-FOXO1A fusion gene negative alveolar rhabdomyosarcoma cell line.

scientific article published on January 2001

Molecular cytogenetic analysis of adult testicular germ cell tumours and identification of regions of consensus copy number change ⬇️

scientific article published on January 1, 1998

Mutations of the BRAF gene in human cancer

scientific article (publication date: 27 June 2002)

Nascent pre-rRNA overexpression correlates with an adverse prognosis in alveolar rhabdomyosarcoma

scientific article published on 01 September 2006

No evidence for epigenetic inactivation of fumarate hydratase in leiomyomas and leiomyosarcomas

article

Novel formation and amplification of the PAX7-FKHR fusion gene in a case of alveolar rhabdomyosarcoma

scientific article published on 01 September 1996

Nuclear overexpression of the E2F3 transcription factor in human lung cancer.

scientific article

Oncocytic Adrenal Cortical Carcinosarcoma With Pleomorphic Rhabdomyosarcomatous Metastases ⬇️

scientific article published on March 1, 2012

Overexpression of genes on 16q associated with cisplatin resistance of testicular germ cell tumor cell lines.

scientific article

PAX3/FOXO1 fusion gene status is the key prognostic molecular marker in rhabdomyosarcoma and significantly improves current risk stratification.

scientific article published on 26 March 2012

PAX7 expression in embryonal rhabdomyosarcoma suggests an origin in muscle satellite cells

scientific article

Pez: a novel human cDNA encoding protein tyrosine phosphatase- and ezrin-like domains

scientific article

Phyllodes tumors of the breast analyzed by comparative genomic hybridization and association of increased 1q copy number with stromal overgrowth and recurrence

scientific article published on 01 November 1997

Polygenic susceptibility to testicular cancer: implications for personalised health care

scientific article published on 13 October 2015

Putting the colours into chromogenic in situ hybridization (CISH)

scientific article published on 01 September 2006

Rapid and accurate determination of MYCN copy number and 1p deletion in neuroblastoma by quantitative PCR.

scientific article published in June 2006

Relationship between MYCN copy number and expression in rhabdomyosarcomas and correlation with adverse prognosis in the alveolar subtype

scientific article published on 01 February 2005

Rhabdomyosarcoma subtyping by immunohistochemical assessment of myogenin: tissue array study and review of the literature.

scientific article published on 21 May 2008

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

scientific article

Stem cell factor as a novel diagnostic marker for early malignant germ cells.

scientific article

TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer.

scientific article

Targeting the insulin-like growth factor pathway in rhabdomyosarcomas: rationale and future perspectives.

scientific article

Testicular germ cell tumours: predisposition genes and the male germ cell niche.

scientific article published on 17 March 2011

Testicular germ-cell cancer.

scientific article

The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.

scientific article published on 31 July 2014

The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx).

scientific article published on 11 November 2013

The SYT protein involved in the t(X;18) synovial sarcoma translocation is a transcriptional activator localised in nuclear bodies

scientific article published on September 1, 1997

The SYT-SSX1 fusion type of synovial sarcoma is associated with increased expression of cyclin A and D1. A link between t(X;18)(p11.2; q11.2) and the cell cycle machinery

scientific article published on 01 August 2002

The genomic landscape of testicular germ cell tumours: from susceptibility to treatment

scientific article

The long non-coding RNA MYCNOS-01 regulates MYCN protein levels and affects growth of MYCN-amplified rhabdomyosarcoma and neuroblastoma cells

scientific article published on 21 February 2018

The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP ⬇️

scientific article published on April 1, 1998

Whole-exome sequencing reveals the mutational spectrum of testicular germ cell tumours

scientific article

Paulina is supported by:

About Paulina

Help