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List of works by Eric Thorin

A Novel Molecular Pathway of Plaque Vulnerability Reveals a Cholesterol-Independent Effect of Statins and Supports Inflammation as a Therapeutic Target

scientific article published on 15 February 2020

A change in the redox environment and thromboxane A2 production precede endothelial dysfunction in mice

scientific article published on 20 July 2007

A single Mediterranean meal does not impair postprandial flow-mediated dilatation in healthy men with subclinical metabolic dysregulations

scientific article published on 8 April 2016

ADCY9 (Adenylate Cyclase Type 9) Inactivation Protects From Atherosclerosis Only in the Absence of CETP (Cholesteryl Ester Transfer Protein)

scientific article published on 01 October 2018

ANGPTL2 is associated with an increased risk of cardiovascular events and death in diabetic patients

scientific article published on 4 August 2016

Activation of ETB receptors regulates the abundance of ET-1 mRNA in vascular endothelial cells.

scientific article published on 18 February 2008

Acute High-Intensity Intermittent Aerobic Exercise Reduces Plasma Angiopoietin-Like 2 in Patients With Coronary Artery Disease

scientific article published on 4 February 2015

Age-Dependent Demethylation of Sod2 Promoter in the Mouse Femoral Artery

scientific article published on 16 February 2016

Age-dependent oxidative stress: toward an irreversible failure in endothelial maintenance

scientific article published on October 2010

Aging associated with mild dyslipidemia reveals that COX-2 preserves dilation despite endothelial dysfunction

scientific article published on 15 September 2006

Alterations in the endothelial G-protein coupled receptor pathway in epicardial arteries and subendocardial arterioles in compensated left ventricular hypertrophy

scientific article published on 29 September 2006

Angiopoietin-like 2 promotes atherogenesis in mice.

scientific article published on 10 May 2013

Angiopoietin-like-2: a multifaceted protein with physiological and pathophysiological properties.

scientific article

Angiotensin II type I and prostaglandin F2α receptors cooperatively modulate signaling in vascular smooth muscle cells

scientific article published on 15 December 2014

Angptl2 is a Marker of Cellular Senescence: The Physiological and Pathophysiological Impact of Angptl2-Related Senescence ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Antiangiogenic activity of aganirsen in nonhuman primate and rodent models of retinal neovascular disease after topical administration.

scientific article

Antiphospholipid antibody-mediated effects in an arterial model of thrombosis are dependent on Toll-like receptor 4.

scientific article

Autoantibodies to heat shock protein 60 promote thrombus formation in a murine model of arterial thrombosis

scientific article

Bariatric Surgery-Induced Lower Angiopoietin-Like 2 Protein Is Associated With Improved Cardiometabolic Profile

scientific article

Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow

scientific article published on 20 January 2012

Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice

scientific article published on 24 December 2010

Cellular senescence in endothelial cells from atherosclerotic patients is accelerated by oxidative stress associated with cardiovascular risk factors

scientific article published on 13 October 2007

Chronic exposure of bovine aortic endothelial cells to native and oxidized LDL modifies phosphatidylinositol metabolism.

scientific article

Chronic treatment with N-acetyl-cystein delays cellular senescence in endothelial cells isolated from a subgroup of atherosclerotic patients

scientific article published on 20 January 2008

Chronically elevated endothelin levels reduce pulmonary vascular reactivity to nitric oxide.

scientific article published on 3 December 2004

Cloning, expression and purification of functionally active human angiopoietin-like protein 2

scientific article published on 3 July 2014

Control of vascular tone by endogenous endothelin-1 in human pial arteries.

scientific article published on January 1998

Crosstalk between endothelin and nitric oxide in the control of vascular tone.

scientific article

Differences between the in vitro vasoconstrictor responses of the tail artery to potassium and norepinephrine between spontaneously hypertensive, renovascular hypertensive, and various strains of normotensive rats

scientific article published on 01 March 1991

Different contribution of endothelial nitric oxide in the relaxation of human coronary arteries of ischemic and dilated cardiomyopathic hearts.

scientific article

EPHB4 Protein Expression in Vascular Smooth Muscle Cells Regulates Their Contractility, and EPHB4 Deletion Leads to Hypotension in Mice

scientific article published on 22 April 2015

Effects of low-dose-rate beta-irradiation on vascular smooth muscle cells: comparison with high-dose-rate exposure

scientific article published on 01 April 1999

Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells.

scientific article published on 24 April 2010

Endothelial G protein beta-subunits trigger nitric oxide-but not endothelium-derived hyperpolarizing factor-dependent dilation in rabbit resistance arteries.

scientific article

Endothelial nitric oxide synthase activation leads to dilatory H2O2 production in mouse cerebral arteries

scientific article published on 13 October 2006

Endothelial progenitor cells bind and inhibit platelet function and thrombus formation

scientific article published on 16 November 2009

Endothelin B receptor-mediated regulation of endothelin-1 content and release in cultured porcine aorta endothelial cell.

scientific article published in May 2002

Endothelin-1 limits vascular smooth muscle beta-adrenergic receptor sensitivity by a PKC-dependent pathway.

scientific article published in October 2003

Endothelin-1 regulates tone of isolated small arteries in the rat: effect of hyperendothelinemia

scientific article published on 01 April 1998

Endothelin-1-induced pulmonary vasoreactivity is regulated by ET(A) and ET(B) receptor interactions

scientific article published on 08 May 2007

Endothelin-3-dependent pulmonary vasoconstriction in monocrotaline-induced pulmonary arterial hypertension.

scientific article published on 15 August 2008

Endothelin-dependent tone limits acetylcholine-induced dilation of resistance coronary vessels after blockade of NO formation in conscious dogs

scientific article published on 01 November 1998

Endothelium-dependent control of cerebrovascular functions through age: exercise for healthy cerebrovascular aging

scientific article published on 21 June 2013

Endothelium-derived endothelin-1

scientific article published on 05 December 2009

Epigenetic Regulatory Effect of Exercise on Glutathione Peroxidase 1 Expression in the Skeletal Muscle of Severely Dyslipidemic Mice.

scientific article

Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure

scientific article published on 5 February 2016

Evolution of the atrial fibrillation substrate in experimental congestive heart failure: angiotensin-dependent and -independent pathways

scientific article published in November 2003

Exercise Lowers Plasma Angiopoietin-Like 2 in Men with Post-Acute Coronary Syndrome

scientific article

Flow-induced dilation is mediated by Akt-dependent activation of endothelial nitric oxide synthase-derived hydrogen peroxide in mouse cerebral arteries.

scientific article published on 12 March 2009

Functional Dosage of Muscarinic Cholinergic Receptor 3 Signalling, Not the Gene Dose, Determines Its Hypertension Pathogenesis

scientific article published on 28 December 2018

Functional cross-talk between endothelial muscarinic and alpha2-adrenergic receptors in rabbit cerebral arteries.

scientific article published in November 1998

HO-1, a new target of PPARdelta with 'anti-atherogenic' properties: is it the one?

scientific article published on 07 January 2010

Heart rate reduction by ivabradine reduces diastolic dysfunction and cardiac fibrosis.

scientific article published on January 2010

Heart rate-associated mechanical stress impairs carotid but not cerebral artery compliance in dyslipidemic atherosclerotic mice

scientific article published on 16 September 2011

Heterogeneity of vascular endothelial cells in normal and disease states.

scientific article published in June 1998

High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation.

scientific article published on 24 August 2017

High Systolic Blood Pressure Induces Cerebral Microvascular Endothelial Dysfunction, Neurovascular Unit Damage, and Cognitive Decline in Mice

scientific article published on 01 January 2019

Human vascular endothelium heterogeneity. A comparative study of cerebral and peripheral cultured vascular endothelial cells.

scientific article published on February 1997

Hypertension and Alzheimer disease: another brick in the wall of awareness

scientific article published on 20 October 2014

Impact of atherosclerotic disease on cerebral microvasculature and tissue oxygenation in awake LDLR-/-hApoB+/+ transgenic mice

scientific article published on 24 October 2019

Influence of micro- and macro-vascular disease and Tumor Necrosis Factor Receptor 1 on the level of lower-extremity amputation in patients with type 2 diabetes.

scientific article published on 8 June 2018

Influence of postangioplasty beta-irradiation on endothelial function in porcine coronary arteries

scientific article published on 01 March 2000

Ivabradine and metoprolol differentially affect cardiac glucose metabolism despite similar heart rate reduction in a mouse model of dyslipidemia

scientific article published on 5 August 2016

Ivabradine reduces heart rate while preserving metabolic fluxes and energy status of healthy normoxic working hearts ⬇️

scientific article published on January 21, 2011

Knockdown of angiopoietin like-2 protects against angiotensin II-induced cerebral endothelial dysfunction in mice.

scientific article published on 19 December 2014

Knockdown of angiopoietin-like 2 mimics the benefits of intermittent fasting on insulin responsiveness and weight loss.

scientific article published in January 2017

Lack of angiopoietin-like-2 expression limits the metabolic stress induced by a high-fat diet and maintains endothelial function in mice

scientific article

Late chronic catechin antioxidant treatment is deleterious to the endothelial function in aging mice with established atherosclerosis.

scientific article published on 09 April 2010

Levels of Angiopoietin-Like-2 Are Positively Associated With Aortic Stiffness and Mortality After Kidney Transplantation

scientific article published on 01 April 2017

Life [ageing] is like riding a bicycle. To keep your [coronary and heart] balance you must keep moving.

scientific article

Lifelong Cyclic Mechanical Strain Promotes Large Elastic Artery Stiffening: Increased Pulse Pressure and Old Age-Related Organ Failure.

scientific article published on 29 December 2015

Lower Methylation of the ANGPTL2 Gene in Leukocytes from Post-Acute Coronary Syndrome Patients

scientific article

Magnetic resonance fingerprinting based on realistic vasculature in mice

scientific article published on 30 December 2016

Measurement of cerebral microvascular compliance in a model of atherosclerosis with optical coherence tomography.

scientific article published on 13 October 2011

Modulation by the endothelium of sympathetic vasoconstriction in an in vitro preparation of the rat tail artery.

scientific article published on January 1994

Mouse strain differences in metabolic fluxes and function of ex vivo working hearts

scientific article

NTPDase1 (CD39) controls nucleotide-dependent vasoconstriction in mouse.

scientific article published on January 2010

Na+/K+ pump and endothelial cell survival: [Na+]i/[K+]i-independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na+]i

scientific article published on 7 April 2004

Neuroprotection after ischemic stroke by activation of angiotensin receptor type 2: why clinical data do not fit the paradigm?

scientific article published on 01 January 2015

Nitric Oxide Inhibits α 2 -Adrenoceptor–Mediated Endothelium-Dependent Vasodilation ⬇️

scientific article published on June 29, 1998

Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP/PS1 Mice

scientific article published on 25 May 2019

Novel Pathogenesis of Hypertension and Diastolic Dysfunction Caused by M3R (Muscarinic Cholinergic 3 Receptor) Signaling

scientific article published on 01 September 2018

Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.

scientific article published in May 2004

On the environmental stress that reshapes our vessels ⬇️

scientific article published on 03 February 2012

Ouabain decreases reactive oxygen species and salvages nitric oxide: or is it the other way around?

scientific article published on 01 October 2008

Oxidized-LDL induced changes in membrane physico-chemical properties and [Ca2+]i of bovine aortic endothelial cells. Influence of vitamin E ⬇️

scientific article published on April 24, 1995

Pathological Continuum From the Rise in Pulse Pressure to Impaired Neurovascular Coupling and Cognitive Decline

scientific article published on 23 March 2020

Pathological aging of the vascular endothelium: are endothelial progenitor cells the sentinels of the cardiovascular system?

scientific article published in October 2005

Pathophysiological plasma ET-1 levels antagonize beta-adrenergic dilation of coronary resistance vessels in conscious dogs.

scientific article

Possible role of Efnb1 protein, a ligand of Eph receptor tyrosine kinases, in modulating blood pressure

scientific article

Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age mice

scientific article

Potent in vivo antiangiogenic effects of GS-101 (5'-TATCCGGAGGGCTCGCCATGCTGCT-3'), an antisense oligonucleotide preventing the expression of insulin receptor substrate-1.

scientific article published on 10 February 2009

Pulse pressure-dependent cerebrovascular eNOS regulation in mice.

scientific article published on 28 January 2016

ROS-sensitive cytochrome P450 activity maintains endothelial dilatation in ageing but is transitory in dyslipidaemic mice.

scientific article published in April 2006

Reduced blood pressure after smooth muscle EFNB2 deletion and the potential association of EFNB2 mutation with human hypertension risk

scientific article published on 17 August 2016

Reduction of plasma angiopoietin-like 2 after cardiac surgery is related to tissue inflammation and senescence status of patients

scientific article published on 08 January 2019

Regression of aortic valve stenosis by ApoA-I mimetic peptide infusions in rabbits.

scientific article published on 14 April 2008

Reversal of endothelin-1 release by stimulation of endothelial alpha2-adrenoceptor contributes to cerebral vasorelaxation

scientific article published on 01 October 1997

Role of ET-1 in the regulation of coronary circulation.

scientific article

Serum tenascin-C is independently associated with increased major adverse cardiovascular events and death in individuals with type 2 diabetes: a French prospective cohort

scientific article published on 10 February 2020

Stress-induced senescence predominates in endothelial cells isolated from atherosclerotic chronic smokers

scientific article published on November 2008

Sympathetic neurotransmission in the tail artery of aging rats.

scientific article

Systolic hypertension-induced neurovascular unit disruption magnifies vascular cognitive impairment in middle-age atherosclerotic LDLr-/-:hApoB+/+ mice

scientific article published on 15 May 2019

The anti-hypercholesterolemic effect of low p53 expression protects vascular endothelial function in mice

scientific article

The cardiovascular physiology and pharmacology of endothelin-1.

scientific article published on January 2010

The impact of pulse pressure on cerebrovascular events leading to age-related cognitive decline.

scientific article published on 16 February 2018

The role of endogenous norepinephrine release in potassium-evoked vasoconstriction of the rat tail artery

scientific article published on 01 November 1991

Therapeutic Potential of Quercetin to Alleviate Endothelial Dysfunction in Age-Related Cardiovascular Diseases ⬇️

journal article from 'Frontiers in Cardiovascular Medicine' published in 2021

Therapeutic Targeting of LRP6 in Cardiovascular Diseases: Challenging But Not Wnt-Possible!

scientific article published on 11 July 2019

Time-dependent beneficial effect of chronic polyphenol treatment with catechin on endothelial dysfunction in aging mice

scientific article published on 14 October 2011

Tracking adiponectin biodistribution via fluorescence molecular tomography indicates increased vascular permeability after streptozotocin-induced diabetes

scientific article published on 16 July 2019

Two distinct pathways account for EDHF-dependent dilatation in the gracilis artery of dyslipidaemic hApoB+/+ mice.

scientific article published on May 2005

Up-regulation of thromboxane A₂ impairs cerebrovascular eNOS function in aging atherosclerotic mice

scientific article published on 27 May 2011

Vascular Disease Risk in Patients With Hypertriglyceridemia: Endothelial Progenitor Cells, Oxidative Stress, Accelerated Senescence, and Impaired Vascular Repair ⬇️

scientific article published on July 20, 2011

Vascular endothelial ageing, heartbeat after heartbeat

scientific article published on 07 July 2009

Vitamin C restores healthy aging in a mouse model for Werner syndrome

scientific article

Working under pressure: coronary arteries and the endothelin system.

scientific article published on 17 March 2010

alpha-Thrombin upregulates G alpha i3 in human vascular endothelial cells

scientific article published on 01 December 1996

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