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List of works by Martin D Tobin

A Genome-wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.

scientific article published on 2 February 2018

A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample

scientific article

A large genome scan for rare CNVs in amyotrophic lateral sclerosis

scientific article

APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema

journal article published in 2014

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

scientific article

Adjusting for bias and unmeasured confounding in Mendelian randomization studies with binary responses

scientific article published on 7 May 2008

Age at menarche and lung function: a Mendelian randomization study.

scientific article published on 17 June 2017

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

scientific article published on 23 February 2015

Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing

scientific article

An integrated approach to the meta-analysis of genetic association studies using Mendelian randomization

scientific article

Analysis with the exome array identifies multiple new independent variants in lipid loci

scientific article published on 27 July 2016

Association of WNK1 gene polymorphisms and haplotypes with ambulatory blood pressure in the general population

scientific article

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

scientific article

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 01 June 2019

Bed occupancy rates and hospital-acquired Clostridium difficile infection: a cohort study

scientific article published on 23 August 2013

Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma

scientific article published on 10 September 2019

Blood pressure loci identified with a gene-centric array

scientific article

Body mass index, asthma, and genetic variation ⬇️

scientific article published on 01 April 2013

CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

scientific article published on 29 September 2017

Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels

scientific article

Cohort Profile: Extended Cohort for E-health, Environment and DNA (EXCEED)

scientific article published on 01 June 2019

Commentary: development of Mendelian randomization: from hypothesis test to 'Mendelian deconfounding'

scientific article published on 01 February 2004

Common Variation in the WNK1 Gene and Blood Pressure in Childhood

article

Common genetic determinants of lung function, subclinical atherosclerosis and risk of coronary artery disease

scientific article

Common genetic variation near the phospholamban gene is associated with cardiac repolarisation: meta-analysis of three genome-wide association studies

scientific article

Common variants in genes underlying monogenic hypertension and hypotension and blood pressure in the general population

scientific article

Common variants near TERC are associated with mean telomere length

scientific article published on 7 February 2010

Copy number variation of the beta-defensin genes in europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma

scientific article published on 03 January 2014

Coronary Artery Disease-Associated Locus on Chromosome 9p21 and Early Markers of Atherosclerosis

scientific article published on 03 July 2008

Covariance components models for longitudinal family data

scientific article

DataSHIELD: resolving a conflict in contemporary bioscience--performing a pooled analysis of individual-level data without sharing the data

scientific article (publication date: October 2010)

Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol

scientific article published on 8 February 2011

Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome).

scientific article published on May 2014

Determinants of day-night difference in blood pressure, a comparison with determinants of daytime and night-time blood pressure

scientific article published on 17 March 2016

Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

scientific article

Discovery of novel heart rate-associated loci using the Exome Chip

scientific article

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

scientific article

Epigenome-wide association study of lung function level and its change

scientific article published on 04 July 2019

Evidence for large-scale gene-by-smoking interaction effects on pulmonary function.

scientific article

Exome chip meta-analysis fine maps causal variants and elucidates the genetic architecture of rare coding variants in smoking and alcohol use

scientific article published on 06 December 2018

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.

scientific article published on 25 February 2016

ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.

scientific article published on 19 February 2018

Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy

scientific article published on 30 September 2011

GSTCD and INTS12 regulation and expression in the human lung

scientific article

Gender and effects of a common genetic variant in the NOS1 regulator NOS1AP on cardiac repolarization in 3761 individuals from two independent populations

Gene-centric meta-analyses for central adiposity traits in up to 57 412 individuals of European descent confirm known loci and reveal several novel associations

scientific article published on 17 December 2013

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci

scientific article published on 20 February 2014

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

scientific article published on 25 February 2019

Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis

scientific article

Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline

scientific article published on 7 February 2017

Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study.

scientific article published on 20 October 2017

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

scientific article published on 6 October 2011

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

scientific article published on 6 February 2017

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.

scientific article published on 30 January 2017

Genome-wide association analysis identifies six new loci associated with forced vital capacity

scientific article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction

scientific article

Genome-wide association studies in lung disease

scientific article published on 19 August 2011

Genome-wide association study identifies 74 loci associated with educational attainment

scientific article published on 11 May 2016

Genome-wide association study identifies five loci associated with lung function

scientific article

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

scientific article

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

scientific article

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

scientific article

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

scientific article

Genome-wide association study of copy number variation with lung function identifies a novel signal of association near BANP for forced vital capacity

scientific article

Genome-wide association study to identify genetic determinants of severe asthma.

scientific article

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function

scientific article

Genomewide association analysis of coronary artery disease

scientific article

Genomic copy number variation, human health, and disease

scientific article published on 15 June 2009

Haplotype estimation for biobank-scale data sets

scientific article

Heritability of early repolarization: a population-based study

scientific article published on 31 January 2011

High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report

scientific article published on 01 January 2019

Human CCL3L1 copy number variation, gene expression, and the role of the CCL3L1-CCR5 axis in lung function.

scientific article published on 21 February 2018

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

scientific article published in Nature Communications

Identifying potential causal effects of age at menarche: a Mendelian randomization phenome-wide association study

scientific article published on 23 March 2020

Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip

scientific article published on 8 November 2012

Integrative pathway genomics of lung function and airflow obstruction

scientific article

International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents

scientific article published on 11 March 2016

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

scientific article published on 12 July 2017

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

scientific article published on 12 June 2017

Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function ⬇️

scientific article

Leukotriene B4production in healthy subjects carrying variants of the arachidonate 5-lipoxygenase-activating protein gene associated with a risk of myocardial infarction

article

Longitudinal data analysis in pedigree studies

scientific article

Mendelian randomisation and causal inference in observational epidemiology

scientific article

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Meta-analysis of Mendelian randomization studies incorporating all three genotypes

scientific article published on 01 December 2008

Meta-analysis of exome array data identifies six novel genetic loci for lung function

scientific article published on 12 January 2018

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Meta-analysis of genetic studies using Mendelian randomization--a multivariate approach

scientific article published in July 2005

Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci

scientific article published on 07 January 2019

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

scientific article published on 11 December 2018

Molecular mechanisms underlying variations in lung function: a systems genetics analysis

scientific article published on 21 September 2015

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 25 February 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank

scientific article

Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report

scientific article

Pedigree and genotyping quality analyses of over 10,000 DNA samples from the Generation Scotland: Scottish Family Health Study

scientific article

Pharmacogenetic interactions and their potential effects on genetic analyses of blood pressure.

scientific article published on 30 November 2010

Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia

scientific article published on 7 August 2017

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Seeking consent to tissue banking: a survey of health professionals in childhood cancer

article

Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation

scientific article

South Asian ethnicity and risk of childhood accidents: an ecological study at enumeration district level in Leicester.

scientific article published in December 2002

Targeted Sequencing of Lung Function Loci in Chronic Obstructive Pulmonary Disease Cases and Controls

scientific article

Teaching and learning about human sexuality in undergraduate medical education

scientific article published in May 2002

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The impact of low-frequency and rare variants on lipid levels

scientific article published on 11 May 2015

The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol

scientific article published on 23 July 2008

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

The role of copy number variation in susceptibility to amyotrophic lateral sclerosis: genome-wide association study and comparison with published loci ⬇️

scientific article

The vitamin D binding protein axis modifies disease severity in lymphangioleiomyomatosis

scientific article published on 01 November 2018

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

scientific article published on 12 September 2016

Tumour necrosis factor gene complex polymorphisms in chronic obstructive pulmonary disease

scientific article published in February 2007

Understanding the impact of pre-analytic variation in haematological and clinical chemistry analytes on the power of association studies

scientific article

Use of FEV1 as a measure of lung health in the UK BiLEVE study - Authors' reply

scientific article published in December 2015

Variants associated with expression have sex-differential effects on lung function

scientific article

What can genetics tell us about the cause of fixed airflow obstruction?

scientific article published on August 2012

Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction.

scientific article

Whole genome sequence analysis of pulmonary function and COPD in 19,996 multi-ethnic participants

scientific article published on 14 October 2020

Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits

scientific article published on 23 May 2017

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