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List of works by Yotis A Senis

A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein

scientific article

A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter.

scientific article published on October 2006

Absence of Fer protein-tyrosine kinase exacerbates leukocyte recruitment in response to endotoxin

scientific article published on 01 May 2002

CD148 enhances platelet responsiveness to collagen by maintaining a pool of active Src family kinases.

scientific article published on 23 March 2010

Cell layer-specific expression of cyclic nucleotide phosphodiesterases in rat arteries: molecular cloning using isolated cell layers from paraformaldehyde-fixed tissues

scientific article published on 01 November 1995

Changes in the pattern of distribution of von Willebrand factor in rat aortic endothelial cells following thrombin generation in vivo

scientific article published on 01 April 1996

Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation

scientific article published on 12 September 2018

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

scientific article published on 13 June 2018

Cross talk between serine/threonine and tyrosine kinases regulates ADP-induced thromboxane generation in platelets.

scientific article

Dominant role of the protein-tyrosine phosphatase CD148 in regulating platelet activation relative to protein-tyrosine phosphatase-1B.

scientific article

Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis ⬇️

scientific article

Enhanced endotoxin sensitivity in fps/fes-null mice with minimal defects in hematopoietic homeostasis.

scientific article

Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis

scientific article published on 26 October 2018

Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis.

scientific article

G6b-B inhibits constitutive and agonist-induced signaling by glycoprotein VI and CLEC-2

scientific article

Global proteomic assessment of the classical protein-tyrosine phosphatome and "Redoxome"

scientific article

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

scientific article published on 22 August 2019

ITIM receptors: more than just inhibitors of platelet activation.

scientific article

Lymphatic blood filling in CLEC-2-deficient mouse models

scientific article published on 04 March 2020

Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148.

scientific article published on 4 January 2018

Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.

scientific article published on 23 March 2017

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function

scientific journal article

Minimal regulation of platelet activity by PECAM-1.

scientific article published on February 2007

Morphological alterations in endothelial cells associated with the release of von Willebrand factor after thrombin generation in vivo

scientific article published on 01 June 1994

Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.

scientific article published on 4 April 2015

Platelet proteomics: state of the art and future perspective.

scientific article published on January 2012

Proplatelets slip slidin' away

scientific article published on 01 January 2015

Protein-tyrosine phosphatases: a new frontier in platelet signal transduction

scientific article published on October 2013

Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets

scientific article published on May 2005

Selective impairment of platelet activation to collagen in the absence of GATA1

scientific article

Signalling through Src family kinase isoforms is not redundant in models of thrombo-inflammatory vascular disease

scientific article published on 04 July 2018

Src family kinases: at the forefront of platelet activation

scientific article published on 12 August 2014

Syk-dependent phosphorylation of CLEC-2: a novel mechanism of hem-immunoreceptor tyrosine-based activation motif signaling

scientific article published on 22 November 2010

TLT-1: please release me, let me go

scientific article published on 01 December 2018

TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

scientific article published on 01 August 2018

Targeted disruption of the murine fps/fes proto-oncogene reveals that Fps/Fes kinase activity is dispensable for hematopoiesis.

scientific article

Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?

scientific article published on 02 March 2018

The transgenic mouse: a new model to delineate platelet and leukocyte functions

scientific article published on 14 November 2018

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

scientific journal article

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis

scientific article published on 11 June 2018

Ups and downs of the ADP phosphoproteome

scientific article published on 01 January 2017

Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.

scientific article

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