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List of works by Takahiro Nomoto

A toolbox of differently sized and labeled PMMA nanoparticles for cellular uptake investigations

An Ethylenediamine-based Switch to Render the Polyzwitterion Cationic at Tumorous pH for Effective Tumor Accumulation of Coated Nanomaterials

scientific article published on 7 March 2018

An injectable spheroid system with genetic modification for cell transplantation therapy.

scientific article published on 31 December 2013

Artificial Control of Gene Silencing Activity Based on siRNA Conjugation with Polymeric Molecule Having Coil-Globule Transition Behavior.

scientific article published on 9 August 2016

Cyclic RGD-linked polymeric micelles for targeted delivery of platinum anticancer drugs to glioblastoma through the blood-brain tumor barrier.

scientific article

Density-tunable conjugation of cyclic RGD ligands with polyion complex vesicles for the neovascular imaging of orthotopic glioblastomas

scientific article

Design of drug delivery systems for physical energy-induced chemical surgery

scientific article published on 22 March 2018

Direct and instantaneous observation of intravenously injected substances using intravital confocal micro-videography ⬇️

scientific article published on October 21, 2010

Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers.

scientific article published on 25 May 2018

Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines

scientific article published on 24 August 2011

Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism.

scientific article

Epirubicin-loaded polymeric micelles effectively treat axillary lymph nodes metastasis of breast cancer through selective accumulation and pH-triggered drug release

scientific article published on 02 November 2018

Evaluation of the dynamics of drug delivery systems (DDS) using intravital real-time confocal laser scanning microscopy

scientific article

Fine-tuning of charge-conversion polymer structure for efficient endosomal escape of siRNA-loaded calcium phosphate hybrid micelles.

scientific article published on 8 April 2014

Hydrothermally synthesized PEGylated calcium phosphate nanoparticles incorporating Gd-DTPA for contrast enhanced MRI diagnosis of solid tumors.

scientific article published on 6 November 2013

In situ quantitative monitoring of polyplexes and polyplex micelles in the blood circulation using intravital real-time confocal laser scanning microscopy ⬇️

scientific article published on March 3, 2011

In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancers

scientific article published on 24 April 2019

Modulated protonation of side chain aminoethylene repeats in N-substituted polyaspartamides promotes mRNA transfection.

scientific article

Multicompartment micelles with adjustable poly(ethylene glycol) shell for efficient in vivo photodynamic therapy

scientific article published on 14 January 2014

Poly( N-isopropylacrylamide)-Based Polymer-Inducing Isothermal Hydrophilic-to-Hydrophobic Phase Transition via Detachment of Hydrophilic Acid-Labile Moiety

scientific article published on 02 January 2019

Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism

scientific article published on 22 January 2020

Polyion complex vesicles for photoinduced intracellular delivery of amphiphilic photosensitizer.

scientific article published on 26 December 2013

Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting

scientific article

Pyruvate Responsiveness Based on α-Oxohydrazone Formation for Intracellular siRNA Release from Polyion Complex-Based Carriers

scientific article published on 23 May 2019

Silica nanogelling of environment-responsive PEGylated polyplexes for enhanced stability and intracellular delivery of siRNA.

scientific article published on 17 October 2012

Systemic Targeting of Lymph Node Metastasis through the Blood Vascular System by Using Size-Controlled Nanocarriers

scientific article

Systemically Injectable Enzyme-Loaded Polyion Complex Vesicles as In Vivo Nanoreactors Functioning in Tumors

scientific article published on 2 December 2015

Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors

scientific article published on 15 January 2014

Targeted polymeric micelles for siRNA treatment of experimental cancer by intravenous injection.

scientific article

Three-layered polyplex micelle as a multifunctional nanocarrier platform for light-induced systemic gene transfer

scientific article published on 2 April 2014

Utility of the 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-Conjugated Polymer Systems

scientific article

Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery.

scientific article published on 15 February 2016

siRNA delivery from triblock copolymer micelles with spatially-ordered compartments of PEG shell, siRNA-loaded intermediate layer, and hydrophobic core

scientific article

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