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List of works by Angela Panoskaltsis-Mortari

3D Bioprinted In Vitro Metastatic Models via Reconstruction of Tumor Microenvironments

scientific article published on 21 January 2019

3D bioprinting for lungs and hollow organs

scientific article published on 14 May 2019

A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls

scientific article published on 18 June 2019

A bispecific recombinant cytotoxin (DTEGF13) targeting human interleukin-13 and epidermal growth factor receptors in a mouse xenograft model of prostate cancer

scientific article published on November 2007

A critical role for CD48 antigen in regulating alloengraftment and lymphohematopoietic recovery after bone marrow transplantation

scientific article published on 01 December 1998

A deimmunized bispecific ligand-directed toxin that shows an impressive anti-pancreatic cancer effect in a systemic nude mouse orthotopic model

scientific article published in July 2012

A new murine model for bronchiolitis obliterans post-bone marrow transplant

scientific article

A novel system for simultaneous in vivo tracking and biological assessment of leukemia cells and ex vivo generated leukemia-reactive cytotoxic T cells

scientific article published in June 2004

A phase I clinical, pharmacological, and biological trial of interleukin 6 plus granulocyte-colony stimulating factor after ifosfamide, carboplatin, and etoposide in children with recurrent/refractory solid tumors: enhanced hematological [...]

scientific article

A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer

scientific article published on 20 September 2010

A picornaviral 2A-like sequence-based tricistronic vector allowing for high-level therapeutic gene expression coupled to a dual-reporter system

scientific article published on September 2005

A spontaneous CD8 T cell-dependent autoimmune disease to an antigen expressed under the human keratin 14 promoter

scientific article published on 01 August 2002

Abnormal T cell-dependent B-cell responses in SCID mice receiving allogeneic bone marrow in utero. Severe combined immune deficiency

scientific article published on 08 August 2002

Abnormalities of bone marrow mesenchymal cells in multiple myeloma patients

scientific article

Absence of host tumor necrosis factor receptor 1 attenuates manifestations of idiopathic pneumonia syndrome

scientific article published on 17 December 2004

Acceleration of idiopathic pneumonia syndrome (IPS) in the absence of donor MIP-1 alpha (CCL3) after allogeneic BMT in mice

scientific article

Activated Alveolar Macrophage-Derived Nitric Oxide Predicts the Development of Lung Damage After Marrow Transplantation in Mice

article

Activated notch supports development of cytokine producing NK cells which are hyporesponsive and fail to acquire NK cell effector functions.

scientific article

Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut.

scientific article

Allogeneic natural killer cells for refractory lymphoma

scientific article published on August 3, 2010

Allogeneic stem cell transplantation in fully MHC-matched Mauritian cynomolgus macaques recapitulates diverse human clinical outcomes

scientific article published on 10 November 2017

Altered T-cell entry and egress in the absence of Coronin 1A attenuates murine acute graft versus host disease

scientific article

Amphiregulin in intestinal acute graft-versus-host disease: a possible diagnostic and prognostic aid

scientific article published on 13 November 2018

Amphiregulin modifies the Minnesota Acute Graft-versus-Host Disease Risk Score: results from BMT CTN 0302/0802

article

An Official American Thoracic Society Research Statement: Noninfectious Lung Injury after Hematopoietic Stem Cell Transplantation: Idiopathic Pneumonia Syndrome

scientific article published on May 1, 2011

An experimental study of the recovery of injured porcine lungs with prolonged normothermic cellular ex vivo lung perfusion following donation after circulatory death

scientific article published on 11 May 2017

Analysis of the requirements for the induction of CD4+ T cell alloantigen hyporesponsiveness by ex vivo anti-CD40 ligand antibody

scientific article published on 01 January 2000

Anti-CD3 epsilon F(ab')2 fragments inhibit T cell expansion in vivo during graft-versus-host disease or the primary immune response to nominal antigen

scientific article published on December 15, 1997

Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor.

scientific article

Association of Cerebrospinal Fluid Biomarkers of Central Nervous System Injury With Neurocognitive and Brain Imaging Outcomes in Children Receiving Chemotherapy for Acute Lymphoblastic Leukemia

scientific article published on 12 July 2018

Associations Among Diurnal Salivary Cortisol Patterns, Medication Use, and Behavioral Phenotype Features in a Community Sample of Rett Syndrome

scientific article published on 01 September 2020

Attenuation of acute graft-versus-host disease in the absence of the transcription factor RORγt

scientific article

Automated decellularization of intact, human-sized lungs for tissue engineering

scientific article

B7-H3 expression in donor T cells and host cells negatively regulates acute graft-versus-host disease lethality

scientific article published on 26 March 2015

Bioreactor Development for Lung Tissue Engineering

scientific article

Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production

scientific article

Blockade of CD40 ligand-CD40 interaction impairs CD4+ T cell-mediated alloreactivity by inhibiting mature donor T cell expansion and function after bone marrow transplantation

scientific article published on 01 January 1997

Blockade of programmed death-1 engagement accelerates graft-versus-host disease lethality by an IFN-gamma-dependent mechanism

scientific article

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

scientific article

Breathing New Life Into Lung Transplantation Therapy

scientific article published on September 1, 2010

CC chemokine receptor 8 potentiates donor Treg survival and is critical for the prevention of murine graft-versus-host disease

scientific article published on 24 June 2013

CD28 blockade controls T cell activation to prevent graft-versus-host disease in primates

CD28/B7 interactions are required for sustaining the graft-versus-leukemia effect of delayed post-bone marrow transplantation splenocyte infusion in murine recipients of myeloid or lymphoid leukemia cells

scientific article published on 01 October 1997

CD30/CD30 ligand (CD153) interaction regulates CD4+ T cell-mediated graft-versus-host disease

scientific article published on 01 September 2004

CD45-targeted antibody-drug-conjugate successfully conditions for allogeneic hematopoietic stem cell transplantation

CD47 (integrin-associated protein) engagement of dendritic cell and macrophage counterreceptors is required to prevent the clearance of donor lymphohematopoietic cells

scientific article

Can biomarkers differentiate pain and no pain subgroups of nonverbal children with cerebral palsy? A preliminary investigation based on noninvasive saliva sampling

scientific article

Cardiac functional and histopathologic findings in humans and mice with mucopolysaccharidosis type I: implications for assessment of therapeutic interventions in hurler syndrome

scientific article published on 02 December 2005

Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria.

scientific article

Circulating angiogenic factors associated with response and survival in patients with acute graft-versus-host disease: results from Blood and Marrow Transplant Clinical Trials Network 0302 and 0802

scientific article published on 7 March 2015

Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein

scientific article

Club cell secretory protein improves survival in a murine obliterative bronchiolitis model

scientific article published on 30 August 2013

Co-opting of ClinicalTrials.gov by patient-funded studies

scientific article published on 19 June 2018

Coblockade of the LFA1:ICAM and CD28/CTLA4:B7 pathways is a highly effective means of preventing acute lethal graft-versus-host disease induced by fully major histocompatibility complex-disparate donor grafts

scientific article published on 01 May 1995

Combined OX40L and mTOR blockade controls effector T cell activation while preserving Treg reconstitution after transplant

scientific article published in September 2017

Comparative analysis of murine marrow-derived dendritic cells generated by Flt3L or GM-CSF/IL-4 and matured with immune stimulatory agents on the in vivo induction of antileukemia responses

scientific article published on 08 August 2002

Constitutively active Stat5b in CD4+ T cells inhibits graft-versus-host disease lethality associated with increased regulatory T-cell potency and decreased T effector cell responses

scientific article

Contrasting acute graft-versus-host disease effects of Tim-3/galectin-9 pathway blockade dependent upon the presence of donor regulatory T cells

scientific article published on June 7, 2012

Critical role for CCR5 in the function of donor CD4+CD25+ regulatory T cells during acute graft-versus-host disease

scientific article published on 7 July 2005

Critically Ill Children Have Low Vitamin D-Binding Protein, Influencing Bioavailability of Vitamin D.

scientific article

Cutting edge: sustained expansion of CD8+ T cells requires CD154 expression by Th cells in acute graft versus host disease

scientific article published on 01 April 1999

Cyclophosphamide prevents systemic keratinocyte growth factor-induced up-regulation of surfactant protein A after allogeneic transplant in mice

scientific article published on 01 November 2000

Cytokine Profiles of Severe Influenza Virus-Related Complications in Children

scientific article published on 6 November 2017

Decellularization of Intact Lung Tissue Through Vasculature and Airways Using Negative and Positive Pressure

scientific article

Decreased Laminin Expression by Human Lung Epithelial Cells and Fibroblasts Cultured in Acellular Lung Scaffolds from Aged Mice

scientific article

Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice

scientific article published on 01 December 2006

Dendritic cells pulsed or fused with AML cellular antigen provide comparable in vivo antitumor protective responses

scientific article published on October 2006

Development of a decellularized lung bioreactor system for bioengineering the lung: the matrix reloaded

scientific article

Differential Induction of Type I and Type III Interferons by Swine and Human Origin H1N1 Influenza A Viruses in Porcine Airway Epithelial Cells.

scientific article

Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity

scientific article published on 16 June 2005

Differential roles for CCR5 expression on donor T cells during graft-versus-host disease based on pretransplant conditioning

scientific article published in July 2004

Differentiation of human bronchial epithelial cells: role of hydrocortisone in development of ion transport pathways involved in mucociliary clearance

scientific article published on 15 June 2016

Diminished neo-antigen response to keyhole limpet hemocyanin (KLH) vaccines in patients after treatment with chemotherapy or hematopoietic cell transplantation

scientific article published on 19 August 2005

Distribution of aerosols in mouse lobes by fluorescent imaging

scientific article published on January 25, 2012

Distribution of aerosols in murine obliterative bronchiolitis lungs by fluorescent imaging

scientific article published on 28 June 2012

Donor B-cell alloantibody deposition and germinal center formation are required for the development of murine chronic GVHD and bronchiolitis obliterans

scientific article published on 9 November 2011

Donor CD4+ Foxp3+ regulatory T cells are necessary for posttransplantation cyclophosphamide-mediated protection against GVHD in mice

scientific article

Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality

scientific article published on 03 October 2019

Donor and recipient plasma follistatin levels are associated with acute GvHD in Blood and Marrow Transplant Clinical Trials Network 0402.

scientific article

Early assessment of dosimetric and biological differences of total marrow irradiation versus total body irradiation in rodents

scientific article

Early characteristics of bone deficits in children with Fontan palliation

scientific article published on 20 February 2020

Effect of oral and vaginal hormonal contraceptives on inflammatory blood biomarkers

scientific article

Effective immunization against neuroblastoma using double-transduced tumor cells secreting GM-CSF and interferon-gamma

scientific article published on 01 March 1996

Effects of donor T-cell trafficking and priming site on graft-versus-host disease induction by naive and memory phenotype CD4 T cells

scientific article published on 19 February 2008

Effects of oxidant stress on inflammation and survival of iNOS knockout mice after marrow transplantation

scientific article

Elevated cerebral spinal fluid cytokine levels in boys with cerebral adrenoleukodystrophy correlates with MRI severity

scientific article

Elevation of intracellular cyclic AMP in alloreactive CD4(+) T Cells induces alloantigen-specific tolerance that can prevent GVHD lethality in vivo

scientific article published in May 2007

Endothelial cell expression of tissue factor in sickle mice is augmented by hypoxia/reoxygenation and inhibited by lovastatin

scientific article published on 8 April 2004

Engraftment of severe combined immune deficient mice receiving allogeneic bone marrow via In utero or postnatal transfer.

scientific article

Evaluation of a bispecific biological drug designed to simultaneously target glioblastoma and its neovasculature in the brain

scientific article published on February 4, 2011

Evidence for early fibrosis and increased airway resistance in bone marrow transplant recipient mice deficient in MMP12.

scientific article

Extracellular Matrix Microparticles Improve GelMA Bioink Resolution for 3D Bioprinting at Ambient Temperature

scientific article published in 2022

Exuberant inflammation in nicotinamide adenine dinucleotide phosphate-oxidase-deficient mice after allogeneic marrow transplantation

scientific article published in June 2002

Facilitating resolution of life-threatening acute GVHD with human chorionic gonadotropin and epidermal growth factor

scientific article published on 01 April 2020

Flt3 ligand (FL) treatment of murine donors does not modify graft-versus-host disease (GVHD) but FL treatment of recipients post-bone marrow transplantation accelerates GVHD lethality

scientific article published on 01 January 2001

Follistatin and Soluble Endoglin Predict 1-Year Nonrelapse Mortality after Allogeneic Hematopoietic Cell Transplantation

scientific article published on 10 November 2019

GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28− CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression

scientific article published on September 10, 2010

Genetic alteration of a bispecific ligand-directed toxin targeting human CD19 and CD22 receptors resulting in improved efficacy against systemic B cell malignancy

scientific article published on 26 March 2009

Genetic and immunological parameters governing in vivo susceptibility/resistance to retrovirally induced murine malignant histiocytosis

scientific article published on October 1, 1998

Haploidentical natural killer cells induce remissions in non-Hodgkin lymphoma patients with low levels of immune-suppressor cells

scientific article

Hematopoietic progenitor cell regulation by CD4+CD25+ T cells

scientific article

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

scientific article

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells.

scientific article

Heterogeneity of single cell cytokine gene expression in clonal T cell populations

scientific article published on October 1, 1994

High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation

scientific article published on 01 June 1999

Host factors that impact the biodistribution and persistence of multipotent adult progenitor cells

scientific article published on 12 January 2006

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

scientific article published on 12 September 2013

Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice

scientific article published on 07 April 2018

Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells

scientific article

Human surfactant protein a suppresses T cell-dependent inflammation and attenuates the manifestations of idiopathic pneumonia syndrome in mice

scientific article

IL-10 and TGF-beta induce alloreactive CD4+CD25- T cells to acquire regulatory cell function

scientific article published on 27 February 2003

IL-15 administration following syngeneic bone marrow transplantation prolongs survival of lymphoma bearing mice

scientific article published on 01 September 1996

IL-2-based immunotherapy after autologous transplantation for lymphoma and breast cancer induces immune activation and cytokine release: a phase I/II trial

scientific article

IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation

scientific article published on 20 October 2009

IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function

scientific article published on 4 February 2016

Ibrutinib treatment ameliorates murine chronic graft-versus-host disease

scientific article

Immunotoxin pharmacokinetics: a comparison of the anti-glioblastoma bi-specific fusion protein (DTAT13) to DTAT and DTIL13.

scientific article published in May 2006

Impact of sleep, fatigue, and systemic inflammation on neurocognitive and behavioral outcomes in long-term survivors of childhood acute lymphoblastic leukemia

scientific article published on 27 April 2017

In situ hybridization for cytokine mRNA with digoxigenin-labeled riboprobes. Sensitivity of detection and double label applications

scientific article published on 01 May 1995

In situ hybridization with digoxigenin-labeled RNA probes: facts and artifacts

scientific article published on 01 February 1995

In situ identification of allospecific B cells using pentamers

scientific article

In vitro-differentiated TH17 cells mediate lethal acute graft-versus-host disease with severe cutaneous and pulmonary pathologic manifestations

scientific article published on 28 October 2008

In vivo imaging of graft-versus-host-disease in mice

scientific article published on 8 January 2004

In vivo inhibition of cytokine responsiveness and graft-versus-host disease mortality by rapamycin leads to a clinical-pathological syndrome discrete from that observed with cyclosporin A

scientific article published on 01 May 1996

Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

scientific article

Increasing anticarcinoma activity of an anti-erbB2 recombinant immunotoxin by the addition of an anti-EpCAM sFv.

scientific article published on May 2007

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality

scientific journal article

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality

scientific article published on 14 October 2009

Induction of CD4+ T cell alloantigen-specific hyporesponsiveness by IL-10 and TGF-beta

scientific article published on 01 October 1999

Induction of Major Histocompatibility Complex-mismatched Mouse Lung Allograft Acceptance With Combined Donor Bone Marrow: Lung Transplant Using a 12-Hour Nonmyeloablative Conditioning Regimen

scientific article published on December 2016

Induction of monocyte- and T-cell-attracting chemokines in the lung during the generation of idiopathic pneumonia syndrome following allogeneic murine bone marrow transplantation

scientific article published on 01 August 2000

Inflammatory cytokines and the development of pulmonary complications after allogeneic hematopoietic cell transplantation in patients with inherited metabolic storage disorders

scientific article

Infusion of anti-B7.1 (CD80) and anti-B7.2 (CD86) monoclonal antibodies inhibits murine graft-versus-host disease lethality in part via direct effects on CD4+ and CD8+ T cells

scientific article published on 01 October 1996

Inhibiting retinoic acid signaling ameliorates graft-versus-host disease by modifying T-cell differentiation and intestinal migration

scientific article published on 27 June 2013

Inhibition of acute graft-versus-host disease with retention of graft-versus-tumor effects by the proteasome inhibitor bortezomib

scientific article

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

scientific article published on 01 January 2020

Initial Observations of Salivary Brain-Derived Neurotrophic Factor Levels in Rett Syndrome.

scientific article

Innate immune function and mortality in critically ill children with influenza: a multicenter study

scientific article

Insights into the mechanism of FTY720 and compatibility with regulatory T cells for the inhibition of graft-versus-host disease (GVHD).

scientific article

Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice

scientific article published on 01 August 1999

Intercellular adhesion molecule-I (ICAM-I, CD54) deficiency segregates the unique pathophysiological requirements for generating idiopathic pneumonia syndrome (IPS) versus graft-versus-host disease following allogeneic murine bone marrow transplanta

scientific article published on 01 January 2001

Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study

scientific article

Interleukin-1 or tumor necrosis factor-alpha antagonists do not inhibit graft-versus-host disease induced across the major histocompatibility barrier in mice

scientific article published on 01 December 1995

Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease

scientific article published on 01 November 1998

Interspecies Organogenesis for Human Transplantation

scientific article published on 19 August 2019

Intracranial therapy of glioblastoma with the fusion protein DTAT in immunodeficient mice

scientific article published on January 2007

Intracranial therapy of glioblastoma with the fusion protein DTIL13 in immunodeficient mice.

scientific article published in May 2006

Invariant natural killer T cells ameliorate murine chronic GVHD by expanding donor regulatory T cells

scientific article published on 17 April 2017

Irradiation of singly and doubly transduced murine neuroblastoma cells expressing B7-1 and producing interferon-gamma reduces their capacity to induce systemic immunity

scientific article published on 01 March 1996

KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT

scientific article published on 01 May 2000

Keratinocyte growth factor administered before conditioning ameliorates graft-versus-host disease after allogeneic bone marrow transplantation in mice

scientific article published on 01 November 1998

Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation

scientific article published on 11 March 2008

Keratinocyte growth factor facilitates alloengraftment and ameliorates graft-versus-host disease in mice by a mechanism independent of repair of conditioning-induced tissue injury

scientific article published on 01 December 2000

L-Selectin Is Dispensable for T Regulatory Cell Function Postallogeneic Bone Marrow Transplantation

scientific article published on November 10, 2010

L-Selectin(hi) but not the L-selectin(lo) CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection

scientific article published on 3 August 2004

Lack of GVHD across classical, single minor histocompatibiliTy (miH) locus barriers in mice

scientific article published on 01 February 1996

Large-conductance Ca2+ -activated K+ channel activation by apical P2Y receptor agonists requires hydrocortisone in differentiated airway epithelium

scientific article

Late acute graft-versus-host disease: a prospective analysis of clinical outcomes and circulating angiogenic factors

scientific article

Lethal murine graft-versus-host disease induced by donor gamma/delta expressing T cells with specificity for host nonclassical major histocompatibility complex class Ib antigens

scientific article published on 01 January 1996

Leukocyte migration and graft-versus-host disease

scientific article

Ligation of 4-1BB (CDw137) regulates graft-versus-host disease, graft-versus-leukemia, and graft rejection in allogeneic bone marrow transplant recipients

scientific article published on 01 March 2001

Ligation of OX40 (CD134) regulates graft-versus-host disease (GVHD) and graft rejection in allogeneic bone marrow transplant recipients

scientific article published on 09 January 2003

Low EGF in myeloablative allotransplantation: association with severe acute GvHD in BMT CTN 0402

scientific article published on 05 June 2017

Low day +100 serum epidermal growth factor levels are associated with acute GvHD after allogeneic hematopoietic cell transplantation

scientific article published on 21 November 2016

Lung tissue bioengineering for chronic obstructive pulmonary disease: overcoming the need for lung transplantation from human donors

scientific article published on 05 June 2019

Lung transplant after prolonged ex vivo lung perfusion: predictors of allograft function in swine

scientific article published on 31 July 2018

MSC therapy attenuates obliterative bronchiolitis after murine bone marrow transplant

scientific article

Mactinin, a fragment of cytoskeletal alpha-actinin, is a novel inducer of heat shock protein (Hsp)-90 mediated monocyte activation

scientific article

Measurement of the distribution of aerosols among mouse lobes by fluorescent imaging

scientific article published on 9 April 2010

Memory T cells in GVHD and GVL.

scientific article published on January 2008

Mesenchymal stem cells in the pathogenesis and treatment of bronchopulmonary dysplasia: a clinical review

scientific article published on 25 September 2017

Minimally invasive versus open Roux-en-Y gastric bypass: effect on immune effector cells

scientific article published on 30 August 2008

Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop.

scientific article

Molecular modification of a recombinant anti-CD3epsilon-directed immunotoxin by inducing terminal cysteine bridging enhances anti-GVHD efficacy and reduces organ toxicity in a lethal murine model

scientific article published on 01 August 2000

Molecular modification of a recombinant, bivalent anti-human CD3 immunotoxin (Bic3) results in reduced in vivo toxicity in mice

scientific article published on 01 March 2005

Mouse fetal and embryonic liver cells differentiate human umbilical cord blood progenitors into CD56-negative natural killer cell precursors in the absence of interleukin-15

scientific article published on 4 March 2008

Multipotent adult progenitor cells can suppress graft-versus-host disease via prostaglandin E2 synthesis and only if localized to sites of allopriming

scientific article published on 20 May 2009

Murine and human IL-7 activate STAT5 and induce proliferation of normal human pro-B cells

scientific article published on December 2005

Myeloperoxidase deficiency enhances inflammation after allogeneic marrow transplantation

scientific article published on 12 March 2004

Opposing roles of CD28:B7 and CTLA-4:B7 pathways in regulating in vivo alloresponses in murine recipients of MHC disparate T cells

scientific article published on 01 June 1999

Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis

scientific article published on September 25, 2003

Peyer patches are not required for acute graft-versus-host disease after myeloablative conditioning and murine allogeneic bone marrow transplantation

scientific article published on 13 September 2005

Pirfenidone ameliorates murine chronic GVHD through inhibition of macrophage infiltration and TGF-β production

scientific article

Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells

scientific article published on October 3, 2003

Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease

scientific article published in December 2016

Preclinical studies targeting normal and leukemic hematopoietic cells with Yttrium-90-labeled anti-CD45 antibody in vitro and in vivo in nude mice

scientific article published on April 2003

Preformed antibody, not primed T cells, is the initial and major barrier to bone marrow engraftment in allosensitized recipients

scientific article published on 3 October 2006

Prevention and Mitigation of Acute Radiation Syndrome in Mice by Synthetic Lipopeptide Agonists of Toll-Like Receptor 2 (TLR2)

scientific article published on March 27, 2012

Profound Increase of Lung Airway Resistance in Heart Failure: a Potential Important Contributor for Dyspnea

scientific article published on 24 January 2019

Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality

scientific article published on 13 June 2016

Prolonged EVLP Using OCS Lung: Cellular and Acellular Perfusates

scientific article published on 22 December 2016

Prolonged subcutaneous administration of 852A, a novel systemic toll‐like receptor 7 agonist, to activate innate immune responses in patients with advanced hematologic malignancies

scientific article published on June 20, 2012

Proopiomelanocortin (POMC) sequencing and developmental delay: Preliminary evidence for a SNP in the 3' UTR region of the POMC gene-Possible relevance for biological risk and self-injurious behavior.

scientific article published on 16 July 2018

Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation

scientific article published on 01 June 2002

Proteome Profiling in Lung Injury after Hematopoietic Stem Cell Transplantation

scientific article published on 04 May 2016

RIG-I and TLR4 responses and adverse outcomes in pediatric influenza-related critical illness

scientific article published on 06 February 2020

Radioimmunotherapy of CD22-expressing Daudi tumors in nude mice with a 90Y-labeled anti-CD22 monoclonal antibody

scientific article published on November 2005

Radiotherapy of CD19 expressing Daudi tumors in nude mice with Yttrium-90-labeled anti-CD19 antibody

scientific article published on February 2004

Radiotherapy of CD45-expressing Daudi tumors in nude mice with yttrium-90-labeled, PEGylated anti-CD45 antibody

scientific article published on August 2007

Rapamycin inhibits the generation of graft-versus-host disease- and graft-versus-leukemia-causing T cells by interfering with the production of Th1 or Th1 cytotoxic cytokines

scientific article published on June 1, 1998

Real-time in vivo imaging of stem cells following transgenesis by transposition

scientific article published in July 2005

Renal Denervation Normalizes Arterial Pressure With No Effect on Glucose Metabolism or Renal Inflammation in Obese Hypertensive Mice

scientific article published on 22 August 2016

Renal dysfunction accounts for the dose limiting toxicity of DT390anti- CD3sFv, a potential new recombinant anti-GVHD immunotoxin

scientific article published on September 1, 1997

Repurposing a novel anti-cancer RXR agonist to attenuate acute GVHD and maintain graft-versus-leukemia responses

scientific article published on 24 September 2020

Retroviral immunotoxin gene therapy of acute myelogenous leukemia in mice using cytotoxic T cells transduced with an interleukin 4/diphtheria toxin gene.

scientific article

Retroviral immunotoxin gene therapy of leukemia in mice using leukemia-specific T cells transduced with an interleukin-3/Bax fusion protein gene

scientific article published in December 2003

STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine model

scientific article

Sarcoma derived from cultured mesenchymal stem cells

scientific article published on 12 October 2006

Separation of graft-versus-host disease from graft-versus-leukemia responses by targeting CC-chemokine receptor 7 on donor T cells

scientific article

Sex-based differences in vascular repair with bone marrow cell therapy: relevance of regulatory and Th2-type cytokines

scientific article published in March 2008

Sex-dependent attenuation of plaque growth after treatment with bone marrow mononuclear cells

scientific article published on 18 October 2007

Simultaneous absence of surfactant proteins A and D increases lung inflammation and injury after allogeneic HSCT in mice

scientific article

Soluble MICA is elevated in pancreatic cancer: Results from a population based case-control study

scientific article published on 4 May 2017

Stem cells and cell therapies in lung biology and lung diseases

scientific article

Stem cells and cell therapies in lung biology and lung diseases

scientific article published on 01 June 2011

Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer

scientific article (publication date: 15 April 2005)

Surfactant protein A decreases lung injury and mortality after murine marrow transplantation

scientific article

Surfactant protein A is a required mediator of keratinocyte growth factor after experimental marrow transplantation

scientific article published on 9 May 2003

Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging

scientific article published on 30 November 2006

Systems analysis uncovers inflammatory Th/Tc17-driven modules during acute GVHD in monkey and human T cells

scientific article published on 06 October 2016

T-lymphocyte production of macrophage inflammatory protein-1alpha is critical to the recruitment of CD8(+) T cells to the liver, lung, and spleen during graft-versus-host disease.

scientific article

TLR agonists regulate alloresponses and uncover a critical role for donor APCs in allogeneic bone marrow rejection

scientific article published on 09 July 2008

Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.

scientific article published on 16 March 2016

Targeted afferent renal denervation reduces arterial pressure but not renal inflammation in established DOCA-salt hypertension in the rat

scientific article published on 07 March 2018

Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression

scientific article published on May 27, 2013

Targeting PI3Kδ function for amelioration of murine chronic graft-versus-host disease

scientific article published on 19 March 2019

Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

scientific article published on 7 April 2015

Targeting glioblastoma multiforme with an IL-13/diphtheria toxin fusion protein in vitro and in vivo in nude mice

scientific article

Targeting myeloid leukemia with a DT(390)-mIL-3 fusion immunotoxin: ex vivo and in vivo studies in mice

scientific article published on 01 September 1999

Targeting of inducible costimulator (ICOS) expressed on alloreactive T cells down-regulates graft-versus-host disease (GVHD) and facilitates engraftment of allogeneic bone marrow (BM).

scientific article published on 23 December 2004

Targeting the Canonical Nuclear Factor-κB Pathway with a High-Potency IKK2 Inhibitor Improves Outcomes in a Mouse Model of Idiopathic Pneumonia Syndrome

scientific article

Targeting urokinase-type plasminogen activator receptor on human glioblastoma tumors with diphtheria toxin fusion protein DTAT.

scientific article published in April 2002

The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning

scientific article published on 01 November 2002

The Global Emergence of Unregulated Stem Cell Treatments for Respiratory Diseases. Professional Societies Need to Act.

scientific article published in August 2016

The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide

scientific article published on September 1997

The future of tissue-engineered organs for transplant? It's here!

scientific article published on January 2012

The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia

scientific article published in April 2007

The vimentin intermediate filament network restrains regulatory T cell suppression of graft-versus-host disease

Therapeutic regulatory T-cell adoptive transfer ameliorates established murine chronic GVHD in a CXCR5-dependent manner

scientific article published on 6 July 2016

Therapy for ongoing graft-versus-host disease induced across the major or minor histocompatibility barrier in mice with anti-CD3F(ab')2-ricin toxin A chain immunotoxin

scientific article published on 01 December 1995

Thrombopoietic cytokines in relation to platelet recovery after bone marrow transplantation

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Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9

scientific article published on February 8, 2012

Tissue engineering of the gastroesophageal junction

scientific article published on 17 April 2020

Toll-like receptor-7 agonist administered subcutaneously in a prolonged dosing schedule in heavily pretreated recurrent breast, ovarian, and cervix cancers

scientific article published on 5 September 2010

Tracheal Cartilage Isolation and Decellularization

scientific article published on 21 July 2017

Transient regulatory T-cell (Treg) depletion with IL-2 diphtheria toxin fusion protein enhances clearance of acute myeloid leukemia by haploidentical natural killer (NK) cells.

scientific article published on 7 November 2013

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

scientific article published on 21 July 2008

Unproven Stem Cell Treatments for Lung Disease—An Emerging Public Health Problem

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Urinary-derived human chorionic gonadotropin to induce tolerance and promote healing in steroid-refractory GvHD

scientific article published on 21 September 2015

Visualization of immunotoxin-mediated tumor cell death in vivo

scientific article published on March 2001