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List of works by Tomohiko Takasaki

3 dengue fever cases, infected during a group tour to the Philippines

scientific article

A Case of Dengue Fever and Subsequent Long-lasting Depression Accompanied by Alopecia in a Japanese Traveler Returning from Bali, Indonesia

scientific article published in March 2015

A case of chikungunya fever imported from India to Japan, follow-up of specific IgM and IgG antibodies over a 6-month period.

scientific article published on January 2010

A case of consecutive infection with Zika virus and Chikungunya virus in Bora Bora, French Polynesia

scientific article

A new method for quantitative analysis of the T cell receptor V region repertoires in healthy common marmosets by microplate hybridization assay ⬇️

scientific article published on July 25, 2012

A single mutation in the Japanese encephalitis virus E protein (S123R) increases its growth rate in mouse neuroblastoma cells and its pathogenicity in mice

scientific article

A summary of the imported cases of Chikungunya fever in Japan from 2006 to June 2016.

scientific article published in January 2018

Accumulation of T-cells with selected T-cell receptors in the brains of Japanese encephalitis virus-infected mice

scientific article published in January 2008

Acute disseminated encephalomyelitis following dengue fever

scientific article published on June 2002

An amino acid substitution (V3I) in the Japanese encephalitis virus NS4A protein increases its virulence in mice, but not its growth rate in vitro ⬇️

scientific article published on March 16, 2011

Antibody Responses Determined for Japanese Dengue Fever Patients by Neutralization and Hemagglutination Inhibition Assays Demonstrate Cross-Reactivity between Dengue and Japanese Encephalitis Viruses

scientific article (publication date: July 2003)

Antibody responses in Japanese volunteers after immunization with yellow fever vaccine

scientific article published on September 2002

Antibody responses induced by immunization with a Japanese rabies vaccine determined by neutralization test and enzyme-linked immunosorbent assay

scientific article published in June 2002

Antibody-dependent enhancement of dengue virus infection in vitro by undiluted sera from monkeys infected with heterotypic dengue virus

scientific article published on 20 July 2010

Autochthonous Chikungunya Fever in Traveler Returning to Japan from Cuba

scientific article (publication date: September 2016)

Autochthonous dengue fever, Tokyo, Japan, 2014.

scientific article

Bivalent vaccine platform based on Japanese encephalitis virus (JEV) elicits neutralizing antibodies against JEV and hepatitis C virus

scientific article

CD16(+) natural killer cells play a limited role against primary dengue virus infection in tamarins

scientific article published on 3 December 2011

Changes in hematological and serum biochemical parameters in common marmosets (Callithrix jacchus) after inoculation with dengue virus

scientific article

Characteristics of progressive multifocal leukoencephalopathy clarified through internet-assisted laboratory surveillance in Japan

scientific article

Characterization of Asn130-to-Ala mutant of dengue type 1 virus NS1 protein

scientific article published on 21 February 2008

Characterization of a serine-to-asparagine substitution at position 123 in the Japanese encephalitis virus E protein

scientific article

Characterization of large and small-plaque variants in the Zika virus clinical isolate ZIKV/Hu/S36/Chiba/2016.

scientific article published on 23 November 2017

Characterization of the variable region in the 3' non-translated region of dengue type 1 virus

scientific article

Chikungunya Virus Growth and Fluorescent Labeling: Detection of Chikungunya Virus by Immunofluorescence Assay

scientific article

Chikungunya fever from Malaysia

scientific article published on March 2010

Chikungunya virus isolated from a returnee to Japan from Sri Lanka: isolation of two sub-strains with different characteristics

scientific article published on November 2009

Clinical and radiological features of imported chikungunya fever in Japan: a study of six cases at the National Center for Global Health and Medicine ⬇️

scientific article published on September 23, 2010

Clinical features of 62 imported cases of dengue fever in Japan.

scientific article

Co-immunization with West Nile DNA and inactivated vaccines provides synergistic increases in their immunogenicities in mice

scientific article published on 16 May 2007

Common marmoset (Callithrix jacchus) as a primate model of dengue virus infection: development of high levels of viraemia and demonstration of protective immunity

scientific article published on 22 June 2011

Comparison of Neutralizing Antibody Titers against Japanese Encephalitis Virus Genotype V Strain with Those against Genotype I and III Strains in the Sera of Japanese Encephalitis Patients in Japan in 2016

scientific article published on 29 June 2018

Comprehensive analysis and characterization of the TCR alpha chain sequences in the common marmoset

scientific article published on 20 April 2010

Construction of an infectious cDNA clone of Culex flavivirus, an insect-specific flavivirus from Culex mosquitoes

scientific article published on May 2012

DGV: Dengue Genographic Viewer

scientific article

Demonstration of marmosets (Callithrix jacchus) as a non-human primate model for secondary dengue virus infection: high levels of viraemia and serotype cross-reactive antibody responses consistent with secondary infection of humans

scientific article published on 9 December 2013

Dengue Hemorrhagic Fever in a Japanese Traveler with Pre-existing Japanese Encephalitis Virus Antibody

scientific article

Dengue Sentinel Traveler Surveillance: Monthly and Yearly Notification Trends among Japanese Travelers, 2006-2014

scientific article (publication date: August 2016)

Dengue Virus Infection in Aedes albopictus during the 2014 Autochthonous Dengue Outbreak in Tokyo Metropolis, Japan

scientific article published on 19 March 2018

Dengue Virus Isolation in Mosquito Aedes albopictus Captured During an Outbreak in Tokyo, 2014, by a Method Relying on Antibody-Dependent Enhancement Mechanism Using FcγR-Expressing BHK Cells

scientific article published on 24 October 2016

Dengue Virus, Nepal

scientific article (publication date: March 2008)

Dengue fever as an acute febrile disease after overseas travel: a report of two cases

scientific article published on January 2011

Dengue transmission model by means of viremic adult immuno-competent mouse

scientific article published on 31 March 2014

Dengue virus infection-enhancing activity in serum samples with neutralizing activity as determined by using FcγR-expressing cells

scientific article

Dengue virus infection-enhancing activity of undiluted sera obtained from patients with secondary dengue virus infection

scientific article

Dengue virus isolation relying on antibody-dependent enhancement mechanism using FcγR-expressing BHK cells and a monoclonal antibody with infection-enhancing capacity

scientific article

Dengue virus type 2 isolated from an imported dengue patient in Japan: first isolation of dengue virus from Nepal

scientific article

Dengue virus type-3 infection in a traveler returning from Benin to Japan

scientific article published on July 2012

Dengue-associated hemophagocytic syndrome in a Japanese traveler: a case report

scientific article published on 27 August 2014

Detecting Dengue Virus Nonstructural Protein 1 (NS1) in Urine Samples Using ELISA for the Diagnosis of Dengue Virus Infection

scientific article published on 13 March 2015

Detection of Japanese encephalitis virus genome in Ryukyu wild boars (Sus scrofa riukiuanus) in Okinawa, Japan

scientific article published on March 2008

Detection of Virus-Antibody Immune Complexes in Secondary Dengue Virus Infection

scientific article published on January 2018

Detection of dengue virus genome in urine by real-time reverse transcriptase PCR: a laboratory diagnostic method useful after disappearance of the genome in serum

scientific article

Detection of dengue virus nonstructural protein 1 (NS1) by using ELISA as a useful laboratory diagnostic method for dengue virus infection of international travelers

scientific article published on 8 March 2013

Detection of dengue virus-infected patients among passengers at the quarantine station of the New Tokyo International Airport

scientific article published on December 2002

Detection of higher levels of dengue viremia using FcγR-expressing BHK-21 cells than FcγR-negative cells in secondary infection but not in primary infection

scientific article

Determination of antibody concentration as the main parameter in a dengue virus antibody-dependent enhancement assay using FcγR-expressing BHK cells

scientific article published on 31 July 2013

Development and application of an indirect enzyme-linked immunosorbent assay for serological survey of Japanese encephalitis virus infection in dogs ⬇️

scientific article published on October 6, 2012

Development and evaluation of fluorogenic TaqMan reverse transcriptase PCR assays for detection of dengue virus types 1 to 4.

scientific article published on December 2004

Development of a Japanese encephalitis virus-like particle vaccine in silkworms using codon-optimised prM and envelope genes

scientific article

Development of a novel Dengue-1 virus replicon system expressing secretory Gaussia luciferase for analysis of viral replication and discovery of antiviral drugs

scientific article

Development of a novel dengue virus serotype-specific multiplex real-time reverse transcription-polymerase chain reaction assay for blood screening

scientific article published on 23 October 2016

Development of a particle agglutination assay system for detecting Japanese encephalitis virus-specific human IgM, using hydroxyapatite-coated nylon beads

scientific article published in July 2002

Development of an antibody-dependent enhancement assay for dengue virus using stable BHK-21 cell lines expressing Fc gammaRIIA.

scientific article published on 23 September 2009

Diagnostic tests: Dengue virus

scientific article

Diagnostic tests: Japanese encephalitis virus and the other flavivirus

scientific article published in July 2005

Discrepancy in Dengue Virus Neutralizing Antibody Titers between Plaque Reduction Neutralizing Tests with Fc Receptor (Fc R)-Negative and Fc R-Expressing BHK-21 Cells

scientific article (publication date: March 2010)

Discrimination between dog-related and vampire bat-related rabies viruses in Brazil by strain-specific reverse transcriptase-polymerase chain reaction and restriction fragment length polymorphism analysis

scientific article published in April 2003

Domestic dengue epidemic in Japan, 2014.

scientific article

Dynamics of cellular immune responses in the acute phase of dengue virus infection

scientific article published on 5 February 2013

Effects of the number of amino acid residues in the signal segment upstream or downstream of the NS2B-3 cleavage site on production and secretion of prM/M-E virus-like particles of West Nile virus

scientific article

Establishment and characterization of a cell line from the mosquito Culex tritaeniorhynchus (Diptera: Culicidae) ⬇️

scientific article published on June 16, 2012

Establishment and characterization of two new cell lines from the mosquito Armigeres subalbatus (Coquillett) (Diptera: Culicidae).

scientific article

Evaluation of Macaca radiata as a non-human primate model of Dengue virus infection

scientific article published on 21 February 2018

Evaluation of dengue IgM detection tests using sera from patients with autoimmune diseases

scientific article published on April 2002

First case of chikungunya fever in Japan with persistent arthralgia

scientific article

First report of West Nile fever in Japan

scientific article

First round of external quality assessment of dengue diagnostics in the WHO Western Pacific Region, 2013

scientific article

Flavivirus encephalitis

scientific article published on February 2009

Flavivirus encephalitis: focus on West Nile encephalitis

scientific article

Formation of infectious dengue virus-antibody immune complex in vivo in marmosets (Callithrix jacchus) after passive transfer of anti-dengue virus monoclonal antibodies and infection with dengue virus

scientific article

Fungus-Derived Neoechinulin B as a Novel Antagonist of Liver X Receptor, Identified by Chemical Genetics Using a Hepatitis C Virus Cell Culture System

scientific article

Genetic and biological characterization of Muko virus, a new distinct member of the species Great Island virus (genus Orbivirus, family Reoviridae), isolated from ixodid ticks in Japan

scientific article published on 8 September 2015

Genetic characterization of Yokose virus, a flavivirus isolated from the bat in Japan

scientific article published on February 2005

Genetic characterization of a new insect flavivirus isolated from Culex pipiens mosquito in Japan

scientific article published on 30 October 2006

Genotype-specific and cross-reactive neutralizing antibodies induced by dengue virus infection: detection of antibodies with different levels of neutralizing activities against homologous and heterologous genotypes of dengue virus type 2 in common m

scientific article published on 27 March 2018

High clonality of virus-specific T lymphocytes defined by TCR usage in the brains of mice infected with West Nile virus

scientific article published on 9 September 2011

High-throughput neutralization assay for multiple flaviviruses based on single-round infectious particles using dengue virus type 1 reporter replicon

scientific article published in Scientific Reports

Hirsutine, an Indole Alkaloid of Uncaria rhynchophylla, Inhibits Late Step in Dengue Virus Lifecycle

scientific article published on 30 August 2017

Human antibody response to dengue virus: implications for dengue vaccine design

scientific article

Human monoclonal antibodies against West Nile virus from Japanese encephalitis-vaccinated volunteers

scientific article published on 14 April 2018

Identification and amplification of Japanese encephalitis virus and Getah virus propagated from a single porcine serum sample: a case of coinfection

scientific article published on 2 July 2014

Identification and characterization of the short variable region of the Japanese encephalitis virus 3' NTR.

scientific article

Immune-related gene expression profile in laboratory common marmosets assessed by an accurate quantitative real-time PCR using selected reference genes

scientific article

Immunogenicity of a Japanese encephalitis DNA vaccine candidate in cynomolgus monkeys ⬇️

scientific article published on June 2, 2003

Immunogenicity of single-dose Vero cell-derived Japanese encephalitis vaccine in Japanese adults

scientific article published on 29 January 2014

Importation of dengue virus type 3 to Japan from Tanzania and Cote d'Ivoire

scientific article published on November 2010

Imported dengue fever/dengue hemorrhagic fever cases in Japan ⬇️

scientific article published on October 12, 2011

Imported malaria and dengue fever in returned travelers in Japan from 2005 to 2010 ⬇️

scientific article published on March 18, 2012

In vitro assessment of human endothelial cell permeability: effects of inflammatory cytokines and dengue virus infection

scientific article published on November 2004

In vitro growth, pathogenicity and serological characteristics of the Japanese encephalitis virus genotype V Muar strain

scientific article published on 5 June 2015

Interference in Japanese encephalitis virus infection of Vero cells by a cationic amphiphilic drug, chlorpromazine

scientific article published in July 2003

Involvement of the Fc gamma receptor IIA cytoplasmic domain in antibody-dependent enhancement of dengue virus infection

scientific article published on 23 September 2009

Japanese encephalitis vaccine-facilitated dengue virus infection-enhancement antibody in adults

scientific article

Japanese encephalitis virus in meningitis patients, Japan

scientific article published in March 2005

Japanese encephalitis: surveillance and elimination effort in Japan from 1982 to 2004.

scientific article published on September 2008

Knowledge Obtained from an Elderly Case of Japanese Encephalitis

scientific article published on September 2016

Marmosets (Callithrix jacchus) as a non-human primate model for evaluation of candidate dengue vaccines: induction and maintenance of specific protective immunity against challenges with clinical isolates

scientific article published on 21 November 2017

Mechanism of introduction of exogenous genes into cultured cells using DEAE-dextran-MMA graft copolymer as non-viral gene carrier

scientific article published on 23 July 2009

Molecular and virological analyses of dengue virus responsible for dengue outbreak in East Timor in 2005.

scientific article

Molecular epidemiological analyses of Japanese encephalitis virus isolates from swine in Japan from 2002 to 2004.

scientific article

Molecular epidemiological analysis of Japanese encephalitis virus in China

scientific article published in March 2007

Molecular phylogenetic and evolutionary analyses of Muar strain of Japanese encephalitis virus reveal it is the missing fifth genotype

scientific article

Morphology and infectivity of virus that persistently caused infection in an AGS cell line ⬇️

scientific article published on December 17, 2011

Mosquito-vector infections: West Nile fever

scientific article

Murine typhus from Vietnam, imported into Japan

scientific article published on September 2006

Needle-free jet injection of small doses of Japanese encephalitis DNA and inactivated vaccine mixture induces neutralizing antibodies in miniature pigs and protects against fetal death and mummification in pregnant sows ⬇️

scientific article published on September 17, 2010

Neutralization Assay for Chikungunya Virus Infection: Plaque Reduction Neutralization Test

scientific article

Neutralizing and enhancing antibody responses to five genotypes of dengue virus type 1 (DENV-1) in DENV-1 patients

scientific article published on 2 December 2016

Newly developed TaqMan assay to detect West Nile viruses in a wide range of viral strains.

scientific article published on June 2004

Nineteen nucleotides in the variable region of 3' non-translated region are dispensable for the replication of dengue type 1 virus in vitro

scientific article

Novel antiviral activity of bromocriptine against dengue virus replication

scientific article

Novel dengue virus type 1 from travelers to Yap State, Micronesia

scientific article

Ongoing local transmission of dengue in Japan, August to September 2014.

scientific article

Partial protective effect of inactivated Japanese encephalitis vaccine on lethal West Nile virus infection in mice ⬇️

scientific article published on November 7, 2003

Peripheral blood mononuclear cells increase the permeability of dengue virus-infected endothelial cells in association with downregulation of vascular endothelial cadherin

scientific article

Persistent seropositivity for yellow fever in a previously vaccinated autologous hematopoietic stem cell transplantation recipient

scientific article published on 8 June 2015

Persistent viruses in mosquito cultured cell line suppress multiplication of flaviviruses

article published in 2018

Phylogenetic analysis of dengue viruses isolated from imported dengue patients: possible aid for determining the countries where infections occurred

scientific article

Plaque formation by Japanese encephalitis virus bound to mosquito C6/36 cells after low pH exposure on the cell surface

scientific article published in May 2007

Plasmodium falciparum: development and validation of a measure of intraerythrocytic growth using SYBR Green I in a flow cytometer

scientific article

Possible Case of Novel Spotted Fever Group Rickettsiosis in Traveler Returning to Japan from India

scientific article published on June 2016

Presence of Viral Genome in Urine and Development of Hematuria and Pathological Changes in Kidneys in Common Marmoset (Callithrix jacchus) after Inoculation with Dengue Virus

scientific article

Production and Characterization of Monoclonal Antibodies to Japanese Encephalitis Virus ⬇️

scientific article published on March 22, 2013

Production of dengue 2 envelope domain III in plant using TMV-based vector system

scientific article

Production of single-round infectious chimeric flaviviruses with DNA-based Japanese encephalitis virus replicon

scientific article published on 4 October 2013

Qualitative differences in brain-infiltrating T cells are associated with a fatal outcome in mice infected with Japanese encephalitis virus

scientific article

Rabies virus stimulates nitric oxide production and CXC chemokine ligand 10 expression in macrophages through activation of extracellular signal-regulated kinases 1 and 2.

scientific article published on September 2004

Rapid determination of viral RNA sequences in mosquitoes collected in the field

scientific article published on 17 September 2007

Rapid genome sequencing of RNA viruses

scientific article published on February 2007

Restoration of replication-defective dengue type 1 virus bearing mutations in the N-terminal cytoplasmic portion of NS4A by additional mutations in NS4B ⬇️

scientific article published on September 30, 2010

Ribavirin inhibits Zika virus (ZIKV) replication in vitro and suppresses viremia in ZIKV-infected STAT1-deficient mice

scientific article published on 14 August 2017

Seroprevalence of Japanese encephalitis virus infection in captive Japanese macaques (Macaca fuscata).

scientific article published on 19 April 2014

Serotype-specific and cross-reactive neutralizing antibody responses in cynomolgus monkeys after infection with multiple dengue virus serotypes

scientific article published on 16 March 2011

Severe murine typhus with shock and acute respiratory failure in a Japanese traveler after returning from Thailand

scientific article published on 30 November 2012

Survey of the antibody against japanese encephalitis virus in Ryukyu wild boars (Sus scrofa riukiuanus) in Okinawa, Japan.

scientific article published in September 2007

Susceptibility of Indigenous and Transplanted Mosquito Spp. to Dengue Virus in Japan

scientific article published on 13 March 2015

T-Cell Clones Expressing Different T-Cell Receptors Accumulate in the Brains of Dying and Surviving Mice After Peripheral Infection with Far Eastern Strain of Tick-Borne Encephalitis Virus ⬇️

scientific article published on August 1, 2011

T-cell responses to dengue virus in humans

scientific article published in December 2011

The Effect of Precipitation on the Transmission of Japanese Encephalitis (JE) Virus in Nature: A Complex Effect on Antibody-Positive Rate to JE Virus in Sentinel Pigs ⬇️

scientific article published on 03 May 2013

The first case report of Ross River virus disease in a Japanese patient who returned from Australia

scientific article published on March 2014

The pathogenesis of 3 neurotropic flaviviruses in a mouse model depends on the route of neuroinvasion after viremia

scientific article published on March 2015

Two different dengue virus strains in the Japanese epidemics of 2014.

scientific article

Usefulness of Immunochromatography Method for Malaria and Dengue Fever Diagnosis

scientific article published on January 2015

Utility of Japanese encephalitis virus subgenomic replicon-based single-round infectious particles as antigens in neutralization tests for Zika virus and three other flaviviruses

scientific article (publication date: February 2017)

Vero cell-derived inactivated West Nile (WN) vaccine induces protective immunity against lethal WN virus infection in mice and shows a facilitated neutralizing antibody response in mice previously immunized with Japanese encephalitis vaccine

scientific article

Virological confirmation of concurrent dengue virus serotypes 1 and 4 by virus isolation using Fc-gamma receptor-expressing BHK cells

scientific article

Virus isolation as one of the diagnostic methods for dengue virus infection

scientific article published on April 2002

West Nile fever

scientific article

West Nile fever/encephalitis

scientific article published on December 2007

West Nile fever/encephalitis

scientific article published on February 2003

Whole Genome Sequencing-Based Molecular Epidemiologic Analysis of Autochthonous Dengue Virus Type 1 Strains Circulating in Japan in 2014.

scientific article

Zika fever imported from Thailand to Japan, and diagnosed by PCR in the urines

scientific article

Zika virus -virus and laboratory diagnosis

scientific article published on January 2016

[Case report of aseptic meningitis due to Japanese encephalitis virus].

scientific article published on February 2007

[Dengue fever and dengue hemorrhagic fever].

scientific article published on March 2007

[Dengue virus].

scientific article published on June 2010

[West Nile fever/encephalitis].

scientific article published on March 2007

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