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List of works by Constantin Lapa

(68)Ga-Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression in Glioblastoma.

scientific article published on 25 January 2016

11C-Methionine PET of Myocardial Inflammation in a Rat Model of Experimental Autoimmune Myocarditis

scientific article published on 7 July 2016

11C-Methionine-PET in Multiple Myeloma: A Combined Study from Two Different Institutions

scientific article published on 23 July 2017

11C-Methionine-PET in Multiple Myeloma: Correlation with Clinical Parameters and Bone Marrow Involvement

scientific article published on January 2016

11C-Methionine-PET: a novel and sensitive tool for monitoring of early response to treatment in multiple myeloma

scientific article published on April 2015

18 FDG-PET/CT for prognostic stratification of patients with multiple myeloma relapse after stem cell transplantation

scientific article

18F-FDG PET detects inflammatory infiltrates in spinal cord experimental autoimmune encephalomyelitis lesions.

scientific article

18F-FDG and 11C-Methionine PET/CT in Newly Diagnosed Multiple Myeloma Patients: Comparison of Volume-Based PET Biomarkers

scientific article published on 23 April 2020

18F-FDG, 11C-Methionine, and 68Ga-Pentixafor PET/CT in Patients with Smoldering Multiple Myeloma: Imaging Pattern and Clinical Features

scientific article published on 18 August 2020

18F-Labeled, PSMA-Targeted Radiotracers: Leveraging the Advantages of Radiofluorination for Prostate Cancer Molecular Imaging

scientific article published on 01 January 2020

68Ga-DOTATATE PET/CT Interobserver Agreement for Neuroendocrine Tumor Assessment: Results of a Prospective Study on 50 Patients

scientific article published on 18 August 2016

68Ga-DOTATATE PET/CT for the detection of inflammation of large arteries: correlation with18F-FDG, calcium burden and risk factors.

scientific article

68Ga-PSMA I&T PET/CT for primary staging of prostate cancer

scientific article published on 16 September 2019

68Ga-PSMA-PET/CT in Patients With Biochemical Prostate Cancer Recurrence and Negative 18F-Choline-PET/CT

scientific article

A GRP78-Directed Monoclonal Antibody Recaptures Response in Refractory Multiple Myeloma with Extramedullary Involvement

scientific article published on 30 March 2016

A Voice From the Past: Rediscovering the Virchow Node With Prostate-specific Membrane Antigen-targeted 18F-DCFPyL Positron Emission Tomography Imaging.

scientific article

Absorbed dose estimates from a single measurement one to three days after the administration of 177Lu-DOTATATE/-TOC

scientific article published on 01 January 2017

Activation of brown adipose tissue in hypothyroidism

scientific article published on 29 October 2015

Anti-Inflammatory Effects on Atherosclerotic Lesions Induced by CXCR4-Directed Endoradiotherapy

scientific article published on 01 July 2018

Assessment of coronary flow reserve using a combination of planar first-pass angiography and myocardial SPECT: Comparison with myocardial (15)O-water PET.

scientific article published on 29 July 2016

Assessment of left ventricular systolic and diastolic function in diabetic rat model using Electrocardiography-gated 18F-FDG PET imaging: PS030

scientific article published on 01 September 2017

Assessment of tumor heterogeneity in treatment-naïve adrenocortical cancer patients using (18)F-FDG positron emission tomography.

scientific article published on 2 May 2016

Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma

scientific article published on 15 December 2015

Biodistribution and radiation dosimetry for a probe targeting prostate-specific membrane antigen for imaging and therapy

scientific article published on 16 April 2015

Biodistribution and radiation dosimetry for the chemokine receptor CXCR4-targeting probe 68Ga-pentixafor

scientific article published on 19 February 2015

CIC Mutation as a Molecular Mechanism of Acquired Resistance to Combined BRAF-MEK Inhibition in Extramedullary Multiple Myeloma with Central Nervous System Involvement

scientific article published on 18 October 2019

CIC-Mutation As a Potential Molecular Mechanism of Acquired Resistance to Combined BRAF/MEK Inhibition in CNS Multiple Myeloma ⬇️

scholarly article

CXCR4 Ligands: The Next Big Hit?

scientific article published in September 2017

CXCR4 PET/CT Scan Is Superior to FDG PET/CT Scan in Accurately Defining Marginal Zone Lymphoma Nodal and Extranodal Involvement ⬇️

scholarly article

CXCR4-Directed Imaging in Solid Tumors

scientific article published on 14 August 2019

CXCR4-directed endoradiotherapy induces high response rates in extramedullary relapsed Multiple Myeloma

scientific article

CXCR4-directed theranostics in oncology and inflammation

article published in 2018

CXCR4-targeted positron emission tomography imaging of central nervous system B-cell lymphoma

scientific article published on 24 April 2020

Capabilities of multi-pinhole SPECT with two stationary detectors for in vivo rat imaging

scientific article published on 29 October 2020

Cardiac Manifestation of Acute Lymphoblastic Leukemia

scientific article published on 15 April 2016

Chemokine Receptor 4 Expression in Primary Sjögren's Syndrome

scientific article published on 01 November 2018

Chemokine receptor - Directed imaging and therapy

scientific article published on 12 September 2017

Clinical Utility of Different Approaches for Detection of Late Pseudoprogression in Glioblastoma With O-(2-[18F]Fluoroethyl)-L-Tyrosine PET

scientific article published on 01 September 2019

Comparison of 11C-Choline and 11C-Methionine PET/CT in Multiple Myeloma

scientific article published on 01 August 2019

Comparison of the amino acid tracers 18F-FET and 18F-DOPA in high-grade glioma patients

scientific article

Correction to: Pre-therapy Somatostatin Receptor-Based Heterogeneity Predicts Overall Survival in Pancreatic Neuroendocrine Tumor Patients Undergoing Peptide Receptor Radionuclide Therapy

scientific article published on 01 December 2018

DNA Damage in Blood Leukocytes of Prostate Cancer Patients Undergoing PET/CT Examinations with [68Ga]Ga-PSMA I&T

scientific article published on 07 February 2020

DNA Damage in Peripheral Blood Lymphocytes of Thyroid Cancer Patients After Radioiodine Therapy.

scientific article published on 12 November 2015

DNA damage in blood leucocytes of prostate cancer patients during therapy with Lu-PSMA

scientific article published on 27 April 2019

Detection Rate of 68Ga-PSMA Ligand PET/CT in Patients with Recurrent Prostate Cancer and Androgen Deprivation Therapy

scientific article published on 18 November 2020

Detection of cardiac amyloidosis with 18F-Florbetaben-PET/CT in comparison to echocardiography, cardiac MRI and DPD-scintigraphy

scientific article published on 23 February 2019

Detection of cardiac sarcoidosis by macrophage-directed somatostatin receptor 2-based positron emission tomography/computed tomography

scientific article

Differential diagnosis of parkinsonism: a head-to-head comparison of FDG PET and MIBG scintigraphy

scientific article published on 11 December 2020

Differentiation of an unclear splenic lesion in a patient with cholangiocarcinoma

scientific article published on 01 May 2014

Dose Mapping after Endoradiotherapy with (177)Lu-DOTATATE/-TOC by One Single Measurement after Four Days

scientific article published on 06 June 2017

Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics.

scientific article published in January 2018

FDG PET/CT depicts cutaneous plasmocytoma

scientific article published in October 2014

False-negative 18F-PSMA-1007 PET/CT in metastatic prostate cancer related to high physiologic liver uptake

scientific article published on 27 December 2019

Feasibility of CXCR4-Directed Radioligand Therapy in Advanced Diffuse Large B-Cell Lymphoma

scientific article published on 18 May 2018

First-in-Human Experience of CXCR4-Directed Endoradiotherapy with 177Lu- and 90Y-Labeled Pentixather in Advanced-Stage Multiple Myeloma with Extensive Intra- and Extramedullary Disease.

scientific article published on 12 November 2015

Follow-up of Lesions with Equivocal Radiotracer Uptake on PSMA-Targeted PET in Patients with Prostate Cancer: Predictive Values of the PSMA-RADS-3A and PSMA-RADS-3B Categories

scientific article published on 06 September 2018

Freehand SPECT-guided sentinel lymph node biopsy in early oral squamous cell carcinoma

scientific article published on 17 January 2014

From the Reading Room to the Courtroom-The Use of Molecular Radionuclide Imaging in Criminal Trials

scientific article published on 24 May 2019

Hexokinase-2 Expression in MET-positive FDG-negative Multiple Myeloma

scientific article published on 02 November 2018

High Interobserver Agreement for the Standardized Reporting System SSTR-RADS 1.0 on Somatostatin Receptor PET/CT

scientific article published on 28 August 2020

Imaging Inflammation in Atherosclerosis with CXCR4-directed 68Ga-Pentixafor PET/CT - Correlation with 18F-FDG PET/CT

scientific article published on 25 October 2019

Imaging cardiac sympathetic innervation with MIBG: linear conversion of the heart-to-mediastinum ratio between different collimators

scientific article published on 23 July 2019

Imaging of Chemokine Receptor 4 Expression in Neuroendocrine Tumors - a Triple Tracer Comparative Approach

scientific article

Imaging of myocardial inflammation with somatostatin receptor based PET/CT - A comparison to cardiac MRI.

scientific article

Impact of Novel Antidepressants on Cardiac Metaiodobenzylguanidine (mIBG) Uptake: Experimental Studies in SK-N-SH Cells and Healthy Rabbits

scientific article published in March 2018

Impact of Tumor Burden on Quantitative [Ga] DOTATOC Biodistribution

scientific article published on 01 August 2019

Impact of aging on semiquantitative uptake parameters in normal rated clinical baseline [123I]Ioflupane single photon emission computed tomography/computed tomography

scientific article published on 01 October 2019

Impact of tissue photon attenuation in small animal cardiac PET imaging

scientific article published on 9 November 2016

In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma

scientific article

Influence of CT-based attenuation correction on dopamine transporter SPECT with [(123)I]FP-CIT.

scientific article published on 15 February 2015

Influence of the amount of co-infused amino acids on post-therapeutic potassium levels in peptide receptor radionuclide therapy

scientific article published on 23 August 2014

Initial Clinical Investigation of [18F]Tetrafluoroborate PET/CT in Comparison to [124I]Iodine PET/CT for Imaging Thyroid Cancer

scientific article published on 01 March 2018

Initial Preclinical Evaluation of 18F-Fluorodeoxysorbitol PET as a Novel Functional Renal Imaging Agent

scientific article published on 24 March 2016

Interobserver Agreement for the Standardized Reporting System PSMA-RADS 1.0 on 18F-DCFPyL PET/CT Imaging

scientific article published on 06 September 2018

Intraindividual tumor heterogeneity in NET - Further insight by C-X-C motif chemokine receptor 4-directed imaging

scientific article published on 09 November 2016

Intraoperative 3-D imaging improves sentinel lymph node biopsy in oral cancer.

scientific article

Investigating the Chemokine Receptor 4 as Potential Theranostic Target in Adrenocortical Cancer Patients

scientific article published on 4 November 2016

It's the Metabolism That Makes Macrophages Detectable in the Magnetic Resonance Scanner: Immune Cell Detection by Hyperpolarized 13C Magnetic Resonance Imaging

scientific article published on 01 April 2018

Lack of Spleen Signal on Diffusion Weighted MRI is associated with High Tumor Burden and Poor Prognosis in Multiple Myeloma: A Link to Extramedullary Hematopoiesis?

scientific article published on 09 July 2019

Left Ventricular Diastolic Dysfunction in a Rat Model of Diabetic Cardiomyopathy using ECG-gated F-FDG PET

scientific article published in Scientific Reports

Longitudinal 18F-FDG PET imaging in a rat model of autoimmune myocarditis

scientific article published on 01 April 2019

Metabolic Tumour Volume from PSMA PET/CT Scans of Prostate Cancer Patients during Chemotherapy-Do Different Software Solutions Deliver Comparable Results?

scientific article published on 08 May 2020

Metabolic substrate shift in human induced pluripotent stem cells during cardiac differentiation: Functional assessment using in vitro radionuclide uptake assay

scientific article published on 21 June 2018

Molecular imaging reporting and data systems (MI-RADS): a generalizable framework for targeted radiotracers with theranostic implications

scientific article published on 14 August 2018

Moving into the next era of PET myocardial perfusion imaging: introduction of novel F-labeled tracers

scientific article published on 17 October 2018

New horizons in cardiac innervation imaging: introduction of novel 18F-labeled PET tracers.

scientific article published on 13 September 2017

Novel Functional Renal PET Imaging With 18F-FDS in Human Subjects

scientific article published on 01 May 2019

Novel Noninvasive Nuclear Medicine Imaging Techniques for Cardiac Inflammation

scientific article published on 10 February 2017

Novel Structured Reporting Systems for Theranostic Radiotracers

scientific article published on 22 February 2019

Novel functional renal imaging with 18F-FDS PET in rat models of kidney diseases

scientific article published on 14 December 2017

O-(2-(18F)fluoroethyl)-L-tyrosine PET for the differentiation of tumour recurrence from late pseudoprogression in glioblastoma

scientific article published on 28 April 2018

Objective Response and Prolonged Disease Control of Advanced Adrenocortical Carcinoma with Cabozantinib

scientific article published on 01 May 2020

PET imaging of noradrenaline transporters in Parkinson's disease: focus on scan time

scientific article published on 06 October 2018

Paralytic subileus as an adverse effect of amino acid-based nephroprotection in a patient undergoing peptide receptor radionuclide therapy

scientific article published on 01 March 2015

Pasotuxizumab, a BiTE® immune therapy for castration-resistant prostate cancer: Phase I, dose-escalation study findings

scientific article published on 10 November 2020

Patterns of uptake of prostate-specific membrane antigen (PSMA)-targeted (18)F-DCFPyL in peripheral ganglia

scientific article published on 22 August 2017

Peptide Receptor Radionuclide Therapy for Sarcoidosis

scientific article published in December 2016

Peptide receptor radionuclide therapy as a new tool in treatment-refractory sarcoidosis - initial experience in two patients

scientific article published in January 2018

Peptide-Receptor Radiotherapy with CXCR4-Targeting Pentixather Reduces Leukemia Burden in Acute Leukemia PDX and Patients ⬇️

scholarly article

Performance evaluation of fifth-generation ultra-high-resolution SPECT system with two stationary detectors and multi-pinhole imaging

scientific article published on 02 November 2020

Potential influence of concomitant chemotherapy on CXCR4 expression in receptor directed endoradiotherapy

scientific article

Pre-therapy Somatostatin Receptor-Based Heterogeneity Predicts Overall Survival in Pancreatic Neuroendocrine Tumor Patients Undergoing Peptide Receptor Radionuclide Therapy

scientific article published on 01 June 2019

Prediction of clinically relevant hyperkalemia in patients treated with peptide receptor radionuclide therapy

scientific article published on 24 December 2014

Predictive value of FDG-PET in patients with advanced medullary thyroid carcinoma treated with vandetanib

scientific article published on 12 October 2017

Preoperative FDG PET/CT in adrenocortical cancer depicts massive venous tumor invasion

scientific article published in June 2014

Pretherapeutic estimation of kidney function in patients treated with peptide receptor radionuclide therapy: can renal scintigraphy be safely omitted?

scientific article published in November 2014

Primary bone marrow diffuse large B-cell lymphoma affecting distal parts of the legs as a cause of persisting B symptoms

scientific article published on 26 March 2014

Primary central nervous system lymphoma and meningioma in DOTATATE PET/CT.

scientific article published in December 2013

Prognostic Value of O-(2-[18F]Fluoroethyl)-L-Tyrosine PET/CT in Newly Diagnosed WHO 2016 Grade II and III Glioma

scientific article published on 01 December 2019

Prognostic value of [18F]FDG-PET/CT in multiple myeloma patients before and after allogeneic hematopoietic cell transplantation

scientific article published on 2 April 2018

Prognostic value of positron emission tomography-assessed tumor heterogeneity in patients with thyroid cancer undergoing treatment with radiopeptide therapy

scientific article published on 20 December 2014

Radionuclide imaging of neurohormonal system of the heart

scientific article published on 15 February 2015

Recent advances in radiotracers targeting norepinephrine transporter: structural development and radiolabeling improvements

scientific article published on 09 April 2020

Recent paradigm shifts in molecular cardiac imaging-Establishing precision cardiology through novel 18F-labeled PET radiotracers

scientific article published on 20 February 2019

Recurrent Extrahepatic Hepatocellular Carcinoma Detected by 18F-Choline PET/CT.

scientific article published on 24 February 2016

Retention Kinetics of the 18F-Labeled Sympathetic Nerve PET Tracer LMI1195: Comparison with 11C-Hydroxyephedrine and 123I-MIBG.

scientific article

SPECT vs. PET in cardiac innervation imaging: clash of the titans

scientific article published on 03 July 2018

SSTR Antagonists as Theranostic Option in Merkel Cell Carcinoma

scholarly article

SSTR-RADS Version 1.0 as a Reporting System for SSTR PET Imaging and Selection of Potential PRRT Candidates: A Proposed Standardization Framework

scientific article published on 23 March 2018

Sarcoid-like reactions: a potential pitfall in oncologic imaging

scientific article published on 24 July 2020

Semiquantitative Parameters in PSMA-Targeted PET Imaging with [18F]DCFPyL: Impact of Tumor Burden on Normal Organ Uptake

scientific article published on 01 February 2020

Sequential CD38 monoclonal antibody retreatment leads to deep remission in a patient with relapsed/refractory multiple myeloma

scientific article published on 01 January 2020

Side Effects of CXC-Chemokine Receptor 4-Directed Endoradiotherapy with Pentixather Before Hematopoietic Stem Cell Transplantation

scientific article published on 08 March 2019

Small-animal PET imaging of isolated perfused rat heart

scientific article published on 30 January 2014

Somatostatin receptor based PET/CT in patients with the suspicion of cardiac sarcoidosis: an initial comparison to cardiac MRI.

scientific article published on 21 October 2016

Somatostatin receptor expression in Merkel cell carcinoma as target for molecular imaging

scientific article

Somatostatin receptor expression in small cell lung cancer as a prognostic marker and a target for peptide receptor radionuclide therapy.

scientific article published on 25 February 2016

Stability of Distribution of F18 Flurpiridaz After Transient Coronary Occlusion in Pigs

scientific article published on 17 July 2019

Subcellular storage and release mode of the novel 18F-labeled sympathetic nerve PET tracer LMI1195.

scientific article published on 6 February 2018

Survival prediction in patients undergoing radionuclide therapy based on intratumoral somatostatin-receptor heterogeneity.

scientific article published on 02 October 2016

Sympathetic nerve damage and restoration after ischemia-reperfusion injury as assessed by (11)C-hydroxyephedrine

scientific article published on 21 August 2015

Targeting CXCR4 with [68Ga]Pentixafor: a suitable theranostic approach in pleural mesothelioma?

scientific article published on 27 May 2017

Targeting paraprotein biosynthesis for non-invasive characterization of myeloma biology

scientific article

The Impact of Ageing on 11C-Hydroxyephedrine Uptake in the Rat Heart.

scientific article published on 24 July 2018

The Link between Cytogenetics/Genomics and Imaging Patterns of Relapse and Progression in Patients with Relapsed/Refractory Multiple Myeloma: A Pilot Study Utilizing 18F-FDG PET/CT

scientific article published on 24 August 2020

The gross picture: intraindividual tumour heterogeneity in a patient with nonsecretory multiple myeloma

scientific article published on 25 February 2017

The impact of 177Lu-octreotide therapy on 99mTc-MAG3 clearance is not predictive for late nephropathy

scientific article published on June 2016

The next era of renal radionuclide imaging: novel PET radiotracers

scientific article published on 30 May 2019

The theranostic promise for Neuroendocrine Tumors in the late 2010s - Where do we stand, where do we go?

scientific article published on 29 November 2018

Theranostics: Leveraging Molecular Imaging and Therapy to Impact Patient Management and Secure the Future of Nuclear Medicine

scientific article published on 10 January 2020

Three-phase bone scintigraphy for imaging osteoradionecrosis of the jaw.

scientific article published in January 2014

Tiger man sign in sarcoid myopathy

scientific article published on 12 January 2019

Tumor localization in ectopic Cushing syndrome using combined PET/CT imaging

scientific article published in September 2013

Tumor-associated macrophages in glioblastoma multiforme-a suitable target for somatostatin receptor-based imaging and therapy?

scientific article

Value of FDG PET/CT in staging of oral cancer: four simultaneous primary malignancies

scientific article

Ventricular Distribution Pattern of the Novel Sympathetic Nerve PET Radiotracer 18F-LMI1195 in Rabbit Hearts

scientific article published on 19 November 2019

Visual and Semiquantitative Accuracy in Clinical Baseline 123I-Ioflupane SPECT/CT Imaging

scientific article published on 01 January 2019

Visualization of tumor heterogeneity in neuroendocrine tumors by positron emission tomography

scientific article

Volumetric and texture analysis of pretherapeutic 18F-FDG PET can predict overall survival in medullary thyroid cancer patients treated with Vandetanib

scientific article published on 11 September 2018

Whitening and Impaired Glucose Utilization of Brown Adipose Tissue in a Rat Model of Type 2 Diabetes Mellitus

scientific article published in December 2017

[(11) C]Methionine emerges as a new biomarker for tracking active myeloma lesions

scientific article published on 3 May 2017

[(68)Ga]Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression After Myocardial Infarction

scientific article published in December 2015

[68Ga]-Pentixafor PET/CT for CXCR4-Mediated Imaging of Vestibular Schwannomas

scientific article published on 12 June 2019

[68Ga]Pentixafor-PET/CT for imaging of chemokine receptor 4 expression in small cell lung cancer--initial experience

scientific article published on 28 January 2016

[68Ga]Pentixafor-PET/CT for imaging of chemokine receptor CXCR4 expression in multiple myeloma - Comparison to [18F]FDG and laboratory values

scientific article published on January 2017

[68Ga]Pentixafor-Positron Emission Tomography/Computed Tomography Detects Chemokine Receptor CXCR4 Expression After Ischemic Stroke

scientific article published on 01 September 2016

[99mTc]Tilmanocept Lymphscintigraphy after inconclusive [99mTc]Nanocolloid Scan in Breast Cancer

scientific article published on 07 May 2019

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