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List of works by Masaki Shiota

A novel antiandrogen, Compound 30, suppresses castration-resistant and MDV3100-resistant prostate cancer growth in vitro and in vivo.

scientific article published on 14 March 2013

Aberrant DNA methylation of T-cell leukemia, homeobox 3 modulates cisplatin sensitivity in bladder cancer ⬇️

scientific article published on May 23, 2011

Androgen receptor cofactors in prostate cancer: potential therapeutic targets of castration-resistant prostate cancer.

scientific article published on September 2011

Antioxidant therapy alleviates oxidative stress by androgen deprivation and prevents conversion from androgen dependent to castration resistant prostate cancer

scientific article published on 16 December 2011

Antitumor activity of recombinant Bacille Calmette-Guérin secreting interleukin-15-Ag85B fusion protein against bladder cancer.

scientific article published on 16 April 2016

Castration resistance of prostate cancer cells caused by castration-induced oxidative stress through Twist1 and androgen receptor overexpression.

scientific article published on 5 October 2009

Castration-resistant prostate cancer: novel therapeutics pre- or post- taxane administration.

scientific article published on May 2013

Cigarette smoking augments androgen receptor activity and promotes resistance to antiandrogen therapy

scientific article published on 11 May 2019

Clusterin Mediates TGF-β–Induced Epithelial–Mesenchymal Transition and Metastasis via Twist1 in Prostate Cancer Cells ⬇️

scientific article published on August 15, 2012

Co-introduction of a steroid with docetaxel chemotherapy for metastatic castration-resistant prostate cancer affects PSA flare

scientific article published on 6 April 2016

Collateral resistance to taxanes in enzalutamide-resistant prostate cancer through aberrant androgen receptor and its variants

Cotargeting Stress-Activated Hsp27 and Autophagy as a Combinatorial Strategy to Amplify Endoplasmic Reticular Stress in Prostate Cancer ⬇️

scientific article published on June 6, 2012

Crosstalk between epithelial-mesenchymal transition and castration resistance mediated by Twist1/AR signaling in prostate cancer

scientific article published on 26 August 2015

Current status of primary pharmacotherapy and future perspectives toward upfront therapy for metastatic hormone-sensitive prostate cancer.

scientific article published on 8 April 2016

DNA topoisomerase inhibitor, etoposide, enhances GC-box-dependent promoter activity via Sp1 phosphorylation

scientific article published on 18 April 2007

Differential Risk of Castration Resistance After Initial Radical Prostatectomy or Radiotherapy for Prostate Cancer.

scientific article

Differential prognostic factors in low- and high-burden de novo metastatic hormone-sensitive prostate cancer patients

scientific article published on 07 November 2020

Downregulation of phosphodiesterase 4B (PDE4B) activates protein kinase A and contributes to the progression of prostate cancer ⬇️

scientific article published on August 30, 2011

Doxycycline induces apoptosis via ER stress selectively to cells with a cancer stem cell-like properties: importance of stem cell plasticity.

scientific article published on 29 November 2017

EP2 signaling mediates suppressive effects of celecoxib on androgen receptor expression and cell proliferation in prostate cancer

scientific article published on 26 November 2013

Ectonucleoside triphosphate diphosphohydrolase 6 expression in testis and testicular cancer and its implication in cisplatin resistance.

scientific article published on 20 April 2011

Editorial Comment to Resumption of anti-programmed cell death 1 monotherapy for severe immune-related adverse events experienced patient with renal cell carcinoma

scientific article published on 25 June 2020

Editorial comment from Dr Shiota to Prognostic impact of young age on stage IV prostate cancer treated with primary androgen deprivation therapy

scientific article published on 09 January 2014

Efficacy and safety of 4-weekly cabazitaxel for castration-resistant prostate cancer: a multi-institutional study

scientific article published on 21 May 2019

Efficacy and safety of cabazitaxel for castration-resistant prostate cancer in patients with > 10 cycles of docetaxel chemotherapy: a multi-institutional study

scientific article published on 28 February 2019

Enhanced S100 calcium-binding protein P expression sensitizes human bladder cancer cells to cisplatin

scientific article published on 19 August 2010

Epithelial to Mesenchymal Transition in Clear Cell Renal Cell Carcinoma with Rhabdoid Features

scientific article

Equol inhibits prostate cancer growth through degradation of androgen receptor by S-phase kinase-associated protein 2.

scientific article published on 18 April 2016

Ets regulates peroxiredoxin1 and 5 expressions through their interaction with the high-mobility group protein B1.

scientific article

FOXO3a Expression Regulated by ERK Signaling is Inversely Correlated With Y-Box Binding Protein-1 Expression in Prostate Cancer.

scientific article published on 04 October 2016

Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin.

scientific article

Foxo3a suppression of urothelial cancer invasiveness through Twist1, Y-box-binding protein 1, and E-cadherin regulation.

scientific article

Gene Polymorphism-related Individual and Interracial Differences in the Outcomes of Androgen Deprivation Therapy for Prostate Cancer

scientific article published on 18 January 2017

Gene amplification of YB-1 in castration-resistant prostate cancer in association with aberrant AR expression

scientific article published on 16 October 2020

Gene polymorphisms in antioxidant enzymes correlate with the efficacy of androgen-deprivation therapy for prostate cancer with implications of oxidative stress

scientific article

Genetic Polymorphism in Sex Hormone-binding Globulin With a Prognosis of Androgen Deprivation Therapy in Metastatic Prostate Cancer Among Japanese Men

scientific article published on 06 April 2019

Genome-wide association study of genetic variations associated with treatment failure after intravesical bacillus Calmette-Guérin therapy for non-muscle invasive bladder cancer

scientific article published on 02 March 2020

High-throughput screen identifies 5-HT receptor as a modulator of AR and a therapeutic target for prostate cancer

scientific article published on 01 June 2020

Histopathologic subtype-specific genomic profiles of renal cell carcinomas identified by high-resolution whole-genome single nucleotide polymorphism array analysis ⬇️

scientific article published on September 23, 2010

Hsp27 regulates EGF/β-catenin mediated epithelial to mesenchymal transition in prostate cancer.

scientific article published on 4 December 2014

Human heterochromatin protein 1 isoform HP1beta enhances androgen receptor activity and is implicated in prostate cancer growth.

scientific article published on 18 May 2010

Human heterochromatin protein 1 isoforms regulate androgen receptor signaling in prostate cancer ⬇️

scientific article published on April 23, 2013

Incidence rate of injection-site granulomas resulting from the administration of luteinizing hormone-releasing hormone analogues for the treatment of prostatic cancer.

scientific article published on June 2007

Increased androgen receptor transcription: a cause of castration-resistant prostate cancer and a possible therapeutic target.

scientific article published on 12 July 2011

Inhibition of RSK/YB-1 signaling enhances the anti-cancer effect of enzalutamide in prostate cancer.

scientific article published on 17 April 2014

Inhibition of protein kinase C/Twist1 signaling augments anticancer effects of androgen deprivation and enzalutamide in prostate cancer.

scientific article published on 18 December 2013

Inhibition of the HER2-YB1-AR axis with Lapatinib synergistically enhances Enzalutamide anti-tumor efficacy in castration resistant prostate cancer

scientific article

Injection-site granulomas resulting from the administration of both leuprorelin acetate and goserelin acetate for the treatment of prostatic cancer

scientific article published on 01 August 2007

Insulin-like growth factor-I induces CLU expression through Twist1 to promote prostate cancer growth.

scientific article published on February 2014

KIFC1 Inhibitor CW069 Induces Apoptosis and Reverses Resistance to Docetaxel in Prostate Cancer

scientific article published on 09 February 2019

Methyltransferase inhibitor adenosine dialdehyde suppresses androgen receptor expression and prostate cancer growth.

scientific article published on 16 May 2012

Metyrapone-responsive ectopic ACTH-secreting pheochromocytoma with a vicious cycle via a glucocorticoid-driven positive-feedback mechanism

scientific article published on 15 May 2018

Mineralocorticoid receptor signaling affects therapeutic effect of enzalutamide

scientific article published on 30 May 2018

Mirabegron induces relaxant effects via cAMP signaling-dependent and -independent pathways in detrusor smooth muscle

scientific article published on 10 January 2019

Mutual regulation between Raf/MEK/ERK signaling and Y-box-binding protein-1 promotes prostate cancer progression.

scientific article published on 9 July 2013

Neoadjuvant androgen-deprivation therapy with radical prostatectomy for prostate cancer in association with age and serum testosterone

scientific article published on 21 November 2017

Novel therapeutic strategies following docetaxel-based chemotherapy in castration-resistant prostate cancer.

scientific article published on November 2010

Nuclear redox imbalance affects circadian oscillation in HaCaT keratinocytes

scientific article published on 28 May 2015

Oxidative stress and androgen receptor signaling in the development and progression of castration-resistant prostate cancer ⬇️

scientific article published on July 23, 2011

P300/CBP-associated factor regulates Y-box binding protein-1 expression and promotes cancer cell growth, cancer invasion and drug resistance.

scientific article

PMA induces androgen receptor downregulation and cellular apoptosis in prostate cancer cells

scientific article published on 29 April 2014

Peroxiredoxin 2 in the nucleus and cytoplasm distinctly regulates androgen receptor activity in prostate cancer cells.

scientific article published on 14 April 2011

Polymorphisms of the androgen transporting gene SLCO2B1 may influence the castration resistance of prostate cancer and the racial differences in response to androgen deprivation.

scientific article published on 30 July 2013

Potential Role for YB-1 in Castration-Resistant Prostate Cancer and Resistance to Enzalutamide Through the Androgen Receptor V7.

scientific article

Pro-survival and anti-apoptotic properties of androgen receptor signaling by oxidative stress promote treatment resistance in prostate cancer

scientific article

Procyanidin B3, an inhibitor of histone acetyltransferase, enhances the action of antagonist for prostate cancer cells via inhibition of p300-dependent acetylation of androgen receptor.

scientific article published on January 2011

Profile of androgen receptor activators identified using high-throughput screen

scientific article published on 20 October 2020

Prognostic Impact of Genetic Polymorphism in Mineralocorticoid Receptor and Comorbidity With Hypertension in Androgen-Deprivation Therapy

scientific article published on 18 December 2018

Prognostic significance of antihypertensive agents in men with castration-resistant prostate cancer

scientific article published on 12 June 2019

Prognostic significance of risk stratification in CHAARTED and LATITUDE studies among Japanese men with de novo metastatic prostate cancer

scientific article published on 21 November 2018

Progression to bone-marrow carcinomatosis and extraosseous legion during treatment with radium-223 for multiple bone metastases

scientific article published on 30 December 2017

Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells.

scientific article published on 30 May 2013

Protein kinase C regulates Twist1 expression via NF-κB in prostate cancer.

scientific article published on 21 February 2017

Psoas muscle volume is correlated with sexual activity and erectile dysfunction among patients with localised prostate cancer

scientific article published on 23 June 2019

Re: Robert J. van Soest, Ellen S. de Morrée, Charlotte F. Kweldam, et al. Targeting the Androgen Receptor Confers In Vivo Cross-resistance Between Enzalutamide and Docetaxel, But Not Cabazitaxel, in Castration-resistant Prostate Cancer. Eur Urol 201

scientific article

Reconsideration on Clinical Benefit of Pelvic Lymph Node Dissection during Radical Prostatectomy for Clinically Localized Prostate Cancer

scientific article published on 30 April 2019

Relationship between body composition and hormone sensitivity for androgen deprivation therapy in patients with metastatic prostate cancer

scientific article published on 30 November 2019

Renal cancer treatment with recipient lymphocyte infusion enhanced the antitumor effect of nonmyeloablative allogeneic stem cell transplantation

scientific article published on 16 December 2014

Renal cell carcinoma with rhabdoid-like features lack intracytoplasmic inclusion bodies and show aggressive behavior.

scientific article published on 9 December 2015

Risk factors for febrile neutropenia in patients receiving docetaxel chemotherapy for castration-resistant prostate cancer.

scientific article published on 5 July 2014

SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1.

scientific article published on 18 January 2018

SRD5A gene polymorphism in Japanese men predicts prognosis of metastatic prostate cancer with androgen-deprivation therapy

scientific article published on 11 July 2015

Secondary bladder cancer after anticancer therapy for prostate cancer: reduced comorbidity after androgen-deprivation therapy

scientific article published on June 2015

Serum testosterone before and during androgen-deprivation therapy, and prognosis between cigarette smokers and nonsmokers with metastatic prostate cancer

scientific article published on 07 August 2018

Serum testosterone level as possible predictive marker in androgen receptor axis-targeting agents and taxane chemotherapies for castration-resistant prostate cancer

scientific article published on 13 November 2018

Significance of prostate-specific antigen-related factors in incidental prostate cancer treated by holmium laser enucleation of the prostate

scientific article

Smoking effect on oncological outcome among men with prostate cancer after radical prostatectomy.

scientific article published on 10 February 2017

Smoking effect on secondary bladder cancer after external beam radiotherapy for prostate cancer

scientific article published on 18 July 2016

Sorafenib augments cytotoxic effect of S-1 in vitro and in vivo through TS suppression.

scientific article published on 5 May 2011

Statins reduce the androgen sensitivity and cell proliferation by decreasing the androgen receptor protein in prostate cancer cells.

scientific article published on 17 August 2010

Sunitinib enhances antitumor effects against chemotherapy-resistant bladder cancer through suppression of ERK1/2 phosphorylation

scientific article

Suppressed Recurrent Bladder Cancer after Androgen Suppression with Androgen Deprivation Therapy or 5α-Reductase Inhibitor

scientific article published on 06 August 2016

Suppression of LIM and SH3 Domain Protein 1 (LASP1) Negatively Regulated by Androgen Receptor Delays Castration Resistant Prostate Cancer Progression

scientific article published on 24 October 2016

TUBB3 Reverses Resistance to Docetaxel and Cabazitaxel in Prostate Cancer

scientific article published on 13 August 2019

Targeting ribosomal S6 kinases/Y-box binding protein-1 signaling improves cellular sensitivity to taxane in prostate cancer

scientific article published on 12 April 2014

Taxane Chemotherapy for Hormone-Naïve Prostate Cancer with Its Expanding Role as Breakthrough Strategy

scientific article

The Association of Polymorphisms in the Gene Encoding Gonadotropin-Releasing Hormone with Serum Testosterone Level during Androgen Deprivation Therapy and Prognosis of Metastatic Prostate Cancer.

scientific article published on 20 September 2017

The Differential Impact of Body Mass Index and the Feature of Metabolic Syndrome on Oncological Outcomes Following Different Surgical Procedures in Japanese Men with Prostate Cancer.

scientific article published on 28 November 2016

The Expression of Ubiquitous Mitochondrial Creatine Kinase Is Downregulated as Prostate Cancer Progression.

scientific article

The Role of Nuclear Receptors in Prostate Cancer

scientific article published on 17 June 2019

The feature of metabolic syndrome is a risk factor for biochemical recurrence after radical prostatectomy

scientific article published on 05 June 2014

The impact of genetic polymorphism on CYP19A1 in androgen-deprivation therapy among Japanese men

scientific article published on 13 March 2019

The important role of glycine N-methyltransferase in the carcinogenesis and progression of prostate cancer.

scientific article published on 13 May 2011

The oncological outcome and validation of Japan Cancer of the Prostate Risk Assessment score among men treated with primary androgen-deprivation therapy.

scientific article published on 17 September 2014

The oncological outcomes and risk stratification in docetaxel chemotherapy for castration-resistant prostate cancer

scientific article published on 20 June 2014

The prognostic impact of serum testosterone during androgen-deprivation therapy in patients with metastatic prostate cancer and the SRD5A2 polymorphism.

scientific article published on 9 February 2016

The significance of strong histone deacetylase 1 expression in the progression of prostate cancer

scientific article published on 25 March 2011

Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance.

scientific article

Twist and p53 reciprocally regulate target genes via direct interaction

scientific article

Twist promotes tumor cell growth through YB-1 expression.

scientific article published in January 2008

Twist1 and Y-box-binding protein-1 are potential prognostic factors in bladder cancer.

scientific article published on 6 February 2013

Twist1 and Y‐box‐binding protein‐1 promote malignant potential in bladder cancer cells ⬇️

scientific article published on November 17, 2010

Validated prognostic significance of YB-1 genetic variation in metastatic prostate cancer

scientific article published on 22 September 2020

Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression.

scientific article published on 11 July 2011

YB-1 suppression induces STAT3 proteolysis and sensitizes renal cancer to interferon-α ⬇️

scientific article published on September 30, 2012

p300 mediates cellular resistance to doxorubicin in bladder cancer.

scientific article published on 20 September 2011

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