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List of works by Paul Lips

1,25-dihydroxyvitamin D3 influences cellular homocysteine levels in murine preosteoblastic MC3T3-E1 cells by direct regulation of cystathionine β-synthase.

scientific article published on December 2011

13th Workshop consensus for vitamin D nutritional guidelines

scientific article published on 17 January 2007

14th Vitamin D Workshop consensus on vitamin D nutritional guidelines

article

A Pooled Analysis of Vitamin D Dose

A Randomized Controlled Trial to Examine the Effect of 2-Year Vitamin B12 and Folic Acid Supplementation on Physical Performance, Strength, and Falling: Additional Findings from the B-PROOF Study

scientific article

A classification tree for predicting recurrent falling in community-dwelling older persons

scientific article published in October 2003

A genome-wide association study of northwestern Europeans involves the C-type natriuretic peptide signaling pathway in the etiology of human height variation

scientific article

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus.

scientific article published on 16 December 2013

A pooled analysis of vitamin D dose requirements for fracture prevention

scientific article

A simple risk score for the assessment of absolute fracture risk in general practice based on two longitudinal studies

scientific article published on May 2009

Adiposity in Relation to Vitamin D Status and Parathyroid Hormone Levels: A Population-Based Study in Older Men and Women

article by Marieke B. Snijder et al published July 2005 in The Journal of Clinical Endocrinology and Metabolism

Agreement between measurement of 25-hydroxyvitamin D3 in dried blood spot samples and serum in a Chinese population in the Netherlands

scientific article published on 21 September 2019

Alendronate with and without cholecalciferol for osteoporosis: results of a 15-week randomized controlled trial

Ambulatory fall-risk assessment: amount and quality of daily-life gait predict falls in older adults

scientific article published on 7 January 2015

Assessing physical activity in older adults: required days of trunk accelerometer measurements for reliable estimation.

scientific article published on 4 December 2013

Associations between medication use and homocysteine levels in an older population, and potential mediation by vitamin B12 and folate: data from the B-PROOF Study

scientific article

Associations of different body fat deposits with serum 25-hydroxyvitamin D concentrations

scientific article published on 18 December 2018

Associations of sarcopenia definitions, and their components, with the incidence of recurrent falling and fractures; the Longitudinal Aging Study Amsterdam.

scientific article published on 30 December 2017

Authors' response: The role of risedronate in osteopenia in Crohn's disease

scientific article published on 25 February 2014

Balance and mobility performance as treatable risk factors for recurrent falling in older persons

scientific article published in July 2003

Beta-blocker use and fall risk in older individuals: Original results from two studies with meta-analysis

scientific article published on 07 June 2017

Body composition and bone measurements in intra-uterine growth retarded and early postnatally undernourished male and female rats at the age of 6 months: comparison with puberty

scientific article published in January 2004

Bone Mineral Density Increases in Trans Persons After 1 Year of Hormonal Treatment: A Multicenter Prospective Observational Study

scientific article

Bone Safety During the First Ten Years of Gender-Affirming Hormonal Treatment in Transwomen and Transmen

scientific article published on 07 December 2018

Bone cells from patients with quiescent Crohn's disease show a reduced growth potential and an impeded maturation

scientific article published on 01 July 2012

Bone histomorphometric and biochemical marker results of a 2-year placebo-controlled trial of raloxifene in postmenopausal women

scientific article published in February 2002

Bone pain and extremely low bone mineral density due to severe vitamin D deficiency in celiac disease ⬇️

scientific article published on June 15, 2011

CYP2C9 Genotypes Modify Benzodiazepine-Related Fall Risk: Original Results From Three Studies With Meta-Analysis.

scientific article published on 23 November 2016

Changes in vitamin D endocrinology during aging in adults

scientific article

Changes of Vitamin D-Binding Protein, and Total, Bioavailable, and Free 25-Hydroxyvitamin D in Transgender People

scientific article published on 01 July 2019

Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.

scientific article published on 24 October 2013

Cognitive Performance: A Cross-Sectional Study on Serum Vitamin D and Its Interplay With Glucose Homeostasis in Dutch Older Adults

scientific article published on 30 March 2015

Comparison of the LASA Physical Activity Questionnaire with a 7-day diary and pedometer

scientific article published on 01 March 2004

Consequences of falling in older men and women and risk factors for health service use and functional decline

scientific article published in January 2004

Controversies in Vitamin D: A Statement From the Third International Conference

scientific article published on 10 November 2020

Correction: Large-Scale Evidence for the Effect of the COLIA1 Sp1 Polymorphism on Osteoporosis Outcomes: The GENOMOS Study

scientific article published on 30 May 2006

Cost-effectiveness of hip protectors in frail institutionalized elderly

scientific article published on 22 April 2004

Cost-utility of medication withdrawal in older fallers: results from the improving medication prescribing to reduce risk of FALLs (IMPROveFALL) trial

scientific article

Current vitamin D status in European and Middle East countries and strategies to prevent vitamin D deficiency: a position statement of the European Calcified Tissue Society

scientific article published on 01 April 2019

Daily oral pamidronate in women and men with osteoporosis: a 3-year randomized placebo-controlled clinical trial with a 2-year open extension

scientific article

Daily-Life Gait Quality as Predictor of Falls in Older People: A 1-Year Prospective Cohort Study.

scientific article

Depression is associated with decreased 25-hydroxyvitamin D and increased parathyroid hormone levels in older adults

scientific article

Determination of fibroblast growth factor 23.

scientific article published on 29 June 2009

Diagnostic Accuracy of 18F-Fluorodeoxyglucose Positron Emission Tomography in the Follow-Up of Papillary or Follicular Thyroid Cancer

Diet, sun, and lifestyle as determinants of vitamin D status

scientific article published on 09 May 2014

Different aspects of visual impairment as risk factors for falls and fractures in older men and women

scientific article published on 10 May 2004

Different cognitive functions in relation to falls among older persons. Immediate memory as an independent risk factor for falls

scientific article published in September 2002

Dr. Koeckhoven, et al reply

scientific article

Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults

scientific article published on 22 January 2019

Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts

Effect of Vitamin B12 and Folic Acid Supplementation on Bone Mineral Density and Quantitative Ultrasound Parameters in Older People with an Elevated Plasma Homocysteine Level: B-PROOF, a Randomized Controlled Trial

scientific article published on 25 February 2015

Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial

scientific article published in October 2014

Effect of long-term growth hormone treatment on bone mass and bone metabolism in growth hormone-deficient men.

scientific article published on 26 June 2005

Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia

scientific article published in January 2007

Effect of moderate-dose vitamin D supplementation on insulin sensitivity in vitamin D-deficient non-Western immigrants in the Netherlands: a randomized placebo-controlled trial

scientific article published on 4 June 2014

Effect of raloxifene treatment on osteocyte apoptosis in postmenopausal women

scientific article

Effect of vitamin B12 and folic acid supplementation on biomarkers of endothelial function and inflammation among elderly individuals with hyperhomocysteinemia

scientific article published on 15 January 2016

Effect of vitamin D supplementation on physical performance and activity in non-western immigrants.

scientific article

Effectiveness of medication withdrawal in older fallers: results from the Improving Medication Prescribing to reduce Risk Of FALLs (IMPROveFALL) trial

scientific article published in January 2017

Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial

scientific article published on September 2015

Effects of Two-Year Vitamin B12 and Folic Acid Supplementation on Depressive Symptoms and Quality of Life in Older Adults with Elevated Homocysteine Concentrations: Additional Results from the B-PROOF Study, an RCT.

scientific article

Effects of daily vitamin D supplementation on respiratory muscle strength and physical performance in vitamin D-deficient COPD patients: a pilot trial

scientific article published on 28 August 2017

Effects of different training modalities on phosphate homeostasis and local vitamin D metabolism in rat bone

article published in 2019

Effects of self-reported osteoarthritis on physical performance: a longitudinal study with a 10-year follow-up.

scientific article

Effects of vitamin D supplementation on markers for cardiovascular disease and type 2 diabetes: an individual participant data meta-analysis of randomized controlled trials.

scientific article published in June 2018

Endocrine and inflammatory markers as predictors of frailty

scientific article published on 01 October 2005

Estimates of optimal vitamin D status

scientific article

European project on osteoarthritis: design of a six-cohort study on the personal and societal burden of osteoarthritis in an older European population

scientific article

Fatty fish and supplements are the greatest modifiable contributors to the serum 25-hydroxyvitamin D concentration in a multiethnic population

scientific article

Functional outcome and quality of life following hip fracture in elderly women: a prospective controlled study ⬇️

scientific article published on November 7, 2003

Gender-specific associations between physical functioning, bone quality, and fracture risk in older people

scientific article published on 24 January 2014

Genetic determinants of heel bone properties: genome-wide association meta-analysis and replication in the GEFOS/GENOMOS consortium

scientific article

Genome-wide Association Study for Radiographic Vertebral Fractures: A Potential Role for the 16q24 BMD Locus versus Lessons Learned from Challenging Phenotype Definition

Genome-wide association study for radiographic vertebral fractures: a potential role for the 16q24 BMD locus

scientific article

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

scientific article

Global Overview of Vitamin D Status

scientific article published in December 2017

High prevalence of vitamin D deficiency in pregnant non-Western women in The Hague, Netherlands

scientific article published on August 2006

Highlights from the 17th workshop on vitamin D, Chicago, IL, June 17-21, 2014.

scientific article

Highlights from the 18th workshop on vitamin D, Delft, The Netherlands, April 21-24, 2015.

scientific article published in November 2016

Highlights from the 19th Workshop on Vitamin D in Boston, March 29-31, 2016.

scientific article published in October 2017

Histomorphometric Analysis Reveals Reduced Bone Mass and Bone Formation in Patients With Quiescent Crohn's Disease ⬇️

scientific article published on September 18, 2010

Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people.

scientific article published on 7 February 2005

Homocysteine level is associated with aortic stiffness in elderly

scientific article published on 01 May 2013

Homocysteine levels and the risk of osteoporotic fracture

scientific article

Impact of incident vertebral fractures on health related quality of life (HRQOL) in postmenopausal women with prevalent vertebral fractures

scientific article published on 19 November 2004

Improvement of thyroid function in hypothyroid patients with rheumatoid arthritis after 6 months of adalimumab treatment: a pilot study

scientific article published on 15 November 2010

Increase in bone mineral density in strictly treated Crohn's disease patients with concomitant calcium and vitamin D supplementation ⬇️

scientific article published on June 27, 2012

Increased expression of matrix extracellular phosphoglycoprotein (MEPE) in cortical bone of the rat tibia after mechanical loading: identification by oligonucleotide microarray

scientific article (publication date: 2013)

Insulin-like growth factor I (IGF-I) and cognitive decline in older persons ⬇️

scientific article published on July 1, 2003

Is Vitamin D Deficiency a Confounder in Alcoholic Skeletal Muscle Myopathy? ⬇️

scientific article published on December 14, 2012

Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis

scientific article published on March 2008

Large-scale analysis of association between polymorphisms in the transforming growth factor beta 1 gene (TGFB1) and osteoporosis: the GENOMOS study

scientific article published on 3 December 2007

Large-scale evidence for the effect of the COLIA1 Sp1 polymorphism on osteoporosis outcomes: the GENOMOS study

scientific article

Late-life anemia is associated with increased risk of recurrent falls

scientific article published in December 2005

Lipid levels: a link between cardiovascular disease and osteoporosis?

scientific article published in June 2009

List of Contributors

Loci at chromosomes 13, 19 and 20 influence age at natural menopause

scientific article

Long-term effects of folic acid and vitamin-B12 supplementation on fracture risk and cardiovascular disease: Extended follow-up of the B-PROOF trial

scientific article published on 05 August 2020

Low free testosterone levels are associated with prevalence and incidence of depressive symptoms in older men.

scientific article published on 25 May 2009

Low grade inflammation is associated with lower velocity of sound and broadband ultrasound attenuation in older men, but not with bone loss or fracture risk in a longitudinal aging study

scientific article published on 15 July 2015

Low serum concentrations of 25-hydroxyvitamin D in older persons and the risk of nursing home admission.

scientific article

Low testosterone levels and decline in physical performance and muscle strength in older men: findings from two prospective cohort studies

Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): the Longitudinal Aging Study Amsterdam

scientific article

MANAGEMENT OF ENDOCRINE DISEASE: The effect of vitamin D supplementation on glycaemic control in patients with type 2 diabetes mellitus: a systematic review and meta-analysis

scientific article

Major depression in late life is associated with both hypo- and hypercortisolemia

scientific article published on 3 May 2007

Maximum potential preventive effect of hip protectors

scientific article published in April 2007

Mechanical stress regulates bone regulatory gene expression independent of estrogen and vitamin D deficiency in rats

scientific article published on 12 June 2020

Medication-related fall incidents in an older, ambulant population: the B-PROOF study

scientific article published on December 2014

Multifactorial intervention to reduce falls in older people at high risk of recurrent falls: a randomized controlled trial

scientific article

Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials

scientific article published on 30 January 2007

Non-linear associations between serum 25-OH vitamin D and indices of arterial stiffness and arteriosclerosis in an older population.

scientific article published on 19 July 2014

Non-skeletal health effects of vitamin D supplementation: A systematic review on findings from meta-analyses summarizing trial data

scientific article

Older individuals with diabetes have an increased risk of recurrent falls: analysis of potential mediating factors: the Longitudinal Ageing Study Amsterdam

scientific article published on 8 December 2011

Once-weekly dose of 8400 IU vitamin D(3) compared with placebo: effects on neuromuscular function and tolerability in older adults with vitamin D insufficiency

scientific article published on 03 February 2010

Ongoing Thyroiditis

scientific article published on 01 November 2007

Optimal vitamin D status: a critical analysis on the basis of evidence-based medicine

scientific article

Osteocalcin as a predictor of the metabolic syndrome in older persons: a population-based study.

scientific article published in February 2013

PTH: A New Target in Arteriosclerosis?

scientific article published on 08 August 2013

Paradoxical reaction on treatment with 131I

scientific article published on 01 December 2006

Plasma osteocalcin levels as a predictor of cardiovascular disease in older men and women: a population-based cohort study

scientific article published on 06 May 2014

Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study

scientific article published on 01 March 2007

Practical operationalizations of risk factors for fracture in older women: results from two longitudinal studies

scientific article published in March 2009

Practice, Efficacy, and Costs of Thyroid Nodule Evaluation: A Retrospective Study in a Dutch University Hospital

scientific article published on 01 April 2004

Prediction of vitamin D deficiency by simple patient characteristics

scientific article published on 19 February 2014

Preventie van valincidenten

Prevention and consequences of vitamin D deficiency in pregnant and lactating women and children: A symposium to prioritise vitamin D on the global agenda

scientific article published on 10 November 2015

Prevention of Hip Fractures by External Hip Protectors

scientific article published in The Journal of the American Medical Association

Prevention of exacerbations in patients with COPD and vitamin D deficiency through vitamin D supplementation (PRECOVID): a study protocol

scientific article published on 23 September 2015

Prevention of fall incidents in patients with a high risk of falling: design of a randomised controlled trial with an economic evaluation of the effect of multidisciplinary transmural care.

scientific article

Primary human osteoblasts in response to 25-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3.

scientific article

Quality of life in patients with osteoporosis

scientific article

Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper

article

Rationale and design of the B-PROOF study, a randomized controlled trial on the effect of supplemental intake of vitamin B12 and folic acid on fracture incidence

scientific article

Recombinant TSH stimulated remnant ablation therapy in thyroid cancer: the success rate depends on the definition of ablation success--an observational study.

scientific article

Reducing fracture risk with calcium and vitamin D.

scientific article published on September 2010

Relationships of serum 25-hydroxyvitamin D to bone mineral density and serum parathyroid hormone and markers of bone turnover in older persons

scientific article published on 21 January 2009

Relative importance of summer sun exposure, vitamin D intake, and genes to vitamin D status in Dutch older adults: The B-PROOF study

scientific article

Results of 2-year vitamin B treatment on cognitive performance: secondary data from an RCT.

scientific article

Serum 25-hydroxyvitamin D levels and the metabolic syndrome in older persons: a population-based study

scientific article published on 01 November 2011

Serum insulin-like growth factor-I and body composition in community dwelling older people

scientific article published on 11 November 2009

Sex differences in the risk of frailty for mortality independent of disability and chronic diseases

scientific article published on 01 January 2005

Short-term oral nutritional intervention with protein and vitamin D decreases falls in malnourished older adults

scientific article published on 8 February 2012

Should vitamin D supplements be recommended to prevent chronic diseases?

scientific article published on 29 January 2015

Skeletal and extra-skeletal actions of vitamin D: Current evidence and outstanding questions

scholarly article by Roger Bouillon et al published 12 October 2018 in Endocrine Reviews

Study protocol: a randomised placebo-controlled clinical trial to study the effect of vitamin D supplementation on glycaemic control in type 2 Diabetes Mellitus SUNNY trial

scientific article

Systematic Review of the Relationship between Vitamin D and Parkinson's Disease

scientific article

T cell-mediated increased osteoclast formation from peripheral blood as a mechanism for Crohn's disease-associated bone loss

scientific article published on 01 January 2012

The Association Between Serum 25-hydroxy Vitamin D Level and Upper Leg Strength in Patients with Knee Osteoarthritis: Results of the Amsterdam Osteoarthritis Cohort

scientific article

The Effect of a Screening and Treatment Program for the Prevention of Fractures in Older Women: A Randomized Pragmatic Trial

scientific article published on 01 August 2019

The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake

scientific article published in September 2010

The When, What & How of Measuring Vitamin D Metabolism in Clinical Medicine

scientific article

The association between common vitamin D receptor gene variations and osteoporosis: a participant-level meta-analysis

scientific article

The association of sex hormone levels with poor mobility, low muscle strength and incidence of falls among older men and women

scientific article published in August 2005

The association of sex hormone levels with quantitative ultrasound, bone mineral density, bone turnover and osteoporotic fractures in older men and women

scientific article published on 06 June 2007

The effect of frailty on residential/nursing home admission in the Netherlands independent of chronic diseases and functional limitations

scientific article published on 9 November 2005

The effect of raloxifene on bone marrow adipose tissue and bone turnover in postmenopausal women with osteoporosis

scientific article published on 11 October 2017

The effect of vitamin D on bone and osteoporosis

scientific article published on August 2011

The effects of the aromatase inhibitor anastrozole on bone metabolism and cardiovascular risk indices in ovariectomized, androgen-treated female-to-male transsexuals

scientific article published in April 2006

The elimination half-life of benzodiazepines and fall risk: two prospective observational studies ⬇️

scientific article published on July 30, 2013

The interrelation between FGF23 and glucose metabolism in humans

scientific article published on 27 June 2018

The relationship between serum 25(OH)D levels and anxiety symptoms in older persons: Results from the Longitudinal Aging Study Amsterdam

scientific article published on 20 April 2017

The role of extracerebral cholesterol homeostasis and ApoE e4 in cognitive decline ⬇️

scientific article published on April 11, 2011

Treatment of bone loss in osteopenic patients with Crohn's disease: a double-blind, randomised trial of oral risedronate 35 mg once weekly or placebo, concomitant with calcium and vitamin D supplementation

scientific article published on 21 October 2013

Validation of the LASA fall risk profile for recurrent falling in older recent fallers

scientific article published on 07 April 2010

Variations in diagnostic performances of dual-energy X-ray absorptiometry in the northwest of The Netherlands

scientific article published on 20 November 2003

Vitamin B12, folic acid, and bone

scientific article published on September 2013

Vitamin D Status Predicts Physical Performance and Its Decline in Older Persons

scientific article published on 06 March 2007

Vitamin D Status and Depressive Symptoms in Older Adults: A Role for Physical Functioning?

scientific article published on 12 March 2018

Vitamin D and mortality: Individual participant data meta-analysis of standardized 25-hydroxyvitamin D in 26916 individuals from a European consortium

scientific article

Vitamin D and osteoporosis in chronic kidney disease

scientific article published on 23 September 2017

Vitamin D and physical performance in older men and women visiting the emergency department because of a fall: data from the improving medication prescribing to reduce risk of falls (IMPROveFALL) study

scientific article published in October 2013

Vitamin D and type 2 diabetes

scientific article

Vitamin D deficiency

scientific article published on 01 November 2007

Vitamin D deficiency in Europe: pandemic?

scientific article

Vitamin D deficiency in immigrants

scientific article published on 11 June 2018

Vitamin D receptor gene haplotype is associated with body height and bone size

scientific article published on 9 January 2007

Vitamin D status in relation to one-year risk of recurrent falling in older men and women

scientific article published on 09 May 2006

Vitamin D status in the Chinese population in the Netherlands: The DRAGON study

scientific article

Vitamin D status, parathyroid function, bone turnover, and BMD in postmenopausal women with osteoporosis: global perspective

scientific article

Vitamin D supplementation and testosterone concentrations in male human subjects

scientific article

Vitamin D supplementation for the prevention of depression and poor physical function in older persons: the D-Vitaal study, a randomized clinical trial

scientific article published on 01 November 2019

Vitamin D supplementation to prevent depression and poor physical function in older adults: Study protocol of the D-Vitaal study, a randomized placebo-controlled clinical trial

scientific article published on 19 November 2015

Vitamin D supplements with or without calcium to prevent fractures

scientific article

Vitamin D, PTH and the risk of overall and disease-specific mortality: Results of the Longitudinal Aging Study Amsterdam.

scientific article

Vitamin D: Giveth to Those Who Needeth

scientific article published on 14 November 2019

Which types of activities are associated with risk of recurrent falling in older persons?

scientific article published on 16 February 2010

Worldwide vitamin D status

scientific article published on August 2011

[Bone densitometry: widening the indication is neither effective nor efficient]

scientific article published on 01 January 2010

[Cost] effectiveness of withdrawal of fall-risk increasing drugs versus conservative treatment in older fallers: design of a multicenter randomized controlled trial (IMPROveFALL-study).

scientific article

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