List of works - Jin-Moo Lee

A case-control study of the effectiveness of tissue plasminogen activator on 6 month patients--reported outcomes and health care utilization

scientific article

ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells

scientific article

Abeta25-35 alters Akt activity, resulting in Bad translocation and mitochondrial dysfunction in cerebrovascular endothelial cells

scientific article published in November 2005

Accuracy of Wearable Cameras to Track Social Interactions in Stroke Survivors.

scientific article published on 9 September 2016

Accuracy of emergency medical services-reported last known normal times in patients suspected with acute stroke.

scientific article published on 18 March 2014

Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes

scientific article published on 8 March 2006

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

scientific article

Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway

scientific article

Application of Machine Learning to Automated Analysis of Cerebral Edema in Large Cohorts of Ischemic Stroke Patients

scholarly article by Rajat Dhar et al published 2018 in Frontiers in Neurology

Author response: Personalizing acute therapies for ischemic stroke: Thrombolysis or thrombectomy?

article

Automated quantification of cerebral edema following hemispheric infarction: Application of a machine-learning algorithm to evaluate CSF shifts on serial head CTs.

scientific article published on 26 September 2016

CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease.

scientific article published on 22 February 2012

CSF Volumetric Analysis for Quantification of Cerebral Edema After Hemispheric Infarction

scientific article published on 5 October 2015

Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain

article

Characterization of a brain permeant fluorescent molecule and visualization of Aβ parenchymal plaques, using real-time multiphoton imaging in transgenic mice

scientific article

Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter

scientific article published on June 2005

Climbing STAIRs towards clinical trials with a novel PARP-1 inhibitor for the treatment of ischemic stroke.

scientific article

Clinically relevant reperfusion in acute ischemic stroke: MTT performs better than Tmax and TTP.

scientific article

Combination therapy for ischemic stroke: potential of neuroprotectants plus thrombolytics.

scientific article published on January 2002

Defining the ischemic penumbra using hyperacute neuroimaging: deriving quantitative ischemic thresholds

scientific article published on May 2012

Developing biomarkers for cerebral amyloid angiopathy trials: do potential disease phenotypes hold promise? - authors' reply

scientific article published in June 2014

Does the white matter matter in Alzheimer disease and cerebral amyloid angiopathy?

scientific article

Early Changes of Tissue Perfusion After Tissue Plasminogen Activator in Hyperacute Ischemic Stroke ⬇️

scientific article published on December 9, 2010

Enhanced Detection of Edema in Malignant Anterior Circulation Stroke (EDEMA) Score: A Risk Prediction Tool

scientific article published on 9 May 2017

Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis

scientific article

Expression profiling identifies a molecular signature of reactive astrocytes stimulated by cyclic AMP or proinflammatory cytokines

scientific article published on 07 November 2007

Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen

scientific article published on 07 January 2019

Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease

scientific article

GISCOME - Genetics of Ischaemic Stroke Functional Outcome network: A protocol for an international multicentre genetic association study

article

Genetic Imbalance Is Associated With Functional Outcome After Ischemic Stroke

scientific article published on 01 February 2019

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.

scientific article published on 8 June 2018

Genetic variation at 16q24.2 is associated with small vessel stroke

scientific article

Genetically Determined Levels of Circulating Cytokines and Risk of Stroke

scientific article published on 01 January 2019

Hospital case-volume is associated with case-fatality after aneurysmal subarachnoid hemorrhage

scientific article published on 18 July 2018

Identification of novel brain biomarkers.

scientific article published on 20 July 2006

Interaction of cardiac implantable electronic device and patent foramen ovale in ischemic stroke: A case-only study

scientific article published on 31 January 2019

Intravenous fibrinolysis eligibility: a survey of stroke clinicians' practice patterns and review of the literature

scientific article

JNK activation contributes to DP5 induction and apoptosis following traumatic spinal cord injury.

scientific article

Lacunes: Black holes in our understanding of cerebral amyloid angiopathy.

scientific article published on 5 May 2017

Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy

scientific article published on 7 December 2016

Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking

scientific article

Magnetic resonance cerebral metabolic rate of oxygen utilization in hyperacute stroke patients

scientific article published in February 2003

Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy

scientific article

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

scientific article

Matrix metalloproteinase-9 in cerebral-amyloid-angiopathy-related hemorrhage

scientific article (publication date: 15 March 2005)

Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.

scientific article published in October 2006

Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury

scientific article published on March 2008

Multifocal stroke with proliferation of small cerebral arteries in hepatopulmonary syndrome

scientific article published on 01 June 2018

Multisensory stimulation improves functional recovery and resting-state functional connectivity in the mouse brain after stroke.

scientific article published on 2 December 2017

Neurologic and neuroimaging manifestations of Cantú syndrome: A case series ⬇️

scientific article published on 17 June 2016

Neuronal activity regulates the regional vulnerability to amyloid-β deposition ⬇️

scientific article published on May 1, 2011

Neuronal apoptosis after CNS injury: the roles of glutamate and calcium.

scientific article

Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis

scientific article

Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association

scientific article published on 29 June 2020

Noninvasive detection of brainstem and spinal cord axonal degeneration in an amyotrophic lateral sclerosis mouse model ⬇️

scientific article published on 08 December 2010

Oligodendrocyte degeneration and recovery after focal cerebral ischemia.

scientific article published on 31 May 2010

Outcome markers for clinical trials in cerebral amyloid angiopathy

scientific article

Oxygen metabolism in ischemic stroke using magnetic resonance imaging.

scientific article

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome

scientific article published on 01 January 2019

Patent foramen ovale and stroke: Should PFOs be closed in otherwise cryptogenic stroke?

scientific article published on 01 July 2010

Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network

scientific article

Pathophysiology of Brain Ischemia

Personalizing acute therapies for ischemic stroke: Thrombolysis or thrombectomy?

scientific article published on 14 February 2018

Photo-activatable Cre recombinase regulates gene expression in vivo

scientific article

Preexisting Statin Use Is Associated With Greater Reperfusion in Hyperacute Ischemic Stroke ⬇️

scientific article published on March 31, 2011

Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death.

scientific article published in February 2006

RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis

scientific article published on 16 July 2021

Rapid perfusion abnormality estimation in acute stroke with temporal correlation analysis

scientific article published on 5 June 2003

Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia.

scientific article published on 18 December 2017

Reducing Door-to-Needle Times Using Toyota’s Lean Manufacturing Principles and Value Stream Analysis ⬇️

scientific article published on November 8, 2012

Refractory giant cell arteritis with spinal cord infarction

scientific article published on 01 December 1997

Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease

scientific article published on 2 March 2018

Remote Limb Ischemic Conditioning and Motor Learning: Evaluation of Factors Influencing Response in Older Adults

scientific article published on 07 August 2018

Remote Limb Ischemic Conditioning at Two Cuff Inflation Pressures Yields Learning Enhancements in Healthy Adults.

scientific article published on 12 October 2016

Remote limb ischemic conditioning enhances motor learning in healthy humans.

scientific article

Reperfusion Beyond 6 Hours Reduces Infarct Probability in Moderately Ischemic Brain Tissue

scientific article

Resident-based acute stroke protocol is expeditious and safe.

scientific article published on 29 January 2009

Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis

scientific journal article

Sensory deprivation after focal ischemia in mice accelerates brain remapping and improves functional recovery through Arc-dependent synaptic plasticity.

scientific article published in January 2018

Separability of calcium slow waves and functional connectivity during wake, sleep, and anesthesia

scientific article published on 13 July 2019

Signal Evolution and Infarction Risk for Apparent Diffusion Coefficient Lesions in Acute Ischemic Stroke Are Both Time- and Perfusion-Dependent ⬇️

scientific article published on March 31, 2011

Silent Infarcts, White Matter Integrity, and Oxygen Metabolic Stress in Young Adults With and Without Sickle Cell Trait

scientific article published in 2022

Silent infarcts in sickle cell disease occur in the border zone region and are associated with low cerebral blood flow

scientific article published on 30 July 2018

Social networks and neurological illness.

scientific article published on 12 September 2016

Spontaneous Infra-slow Brain Activity Has Unique Spatiotemporal Dynamics and Laminar Structure

scientific article published on 29 March 2018

Streamlined Hyperacute Magnetic Resonance Imaging Protocol Identifies Tissue-Type Plasminogen Activator-Eligible Stroke Patients When Clinical Impression Is Stroke Mimic

scientific article published on 18 February 2016

Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes

scientific article

Temporal relationship between apparent diffusion coefficient and absolute measurements of cerebral blood flow in acute stroke patients

scientific article published in January 2003

The changing landscape of ischaemic brain injury mechanisms.

scientific article

Top research priorities for stroke genetics

scientific article published on 17 July 2018

Vascular Permeability Precedes Spontaneous Intracerebral Hemorrhage in Stroke-Prone Spontaneously Hypertensive Rats

scientific article published on 25 October 2007

Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke.

scientific article published on 8 September 2016

Zinc translocation accelerates infarction after mild transient focal ischemia.

scientific article published in January 2002

List of works by Jin-Moo Lee

A case-control study of the effectiveness of tissue plasminogen activator on 6 month patients--reported outcomes and health care utilization

ATM gene regulates oxygen-glucose deprivation-induced nuclear factor-kappaB DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells

Abeta25-35 alters Akt activity, resulting in Bad translocation and mitochondrial dysfunction in cerebrovascular endothelial cells

Accuracy of Wearable Cameras to Track Social Interactions in Stroke Survivors.

Accuracy of emergency medical services-reported last known normal times in patients suspected with acute stroke.

Amyloid beta peptide increases DP5 expression via activation of neutral sphingomyelinase and JNK in oligodendrocytes

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

Amyloid-beta peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway

Application of Machine Learning to Automated Analysis of Cerebral Edema in Large Cohorts of Ischemic Stroke Patients

Author response: Personalizing acute therapies for ischemic stroke: Thrombolysis or thrombectomy?

Automated quantification of cerebral edema following hemispheric infarction: Application of a machine-learning algorithm to evaluate CSF shifts on serial head CTs.

CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease.

CSF Volumetric Analysis for Quantification of Cerebral Edema After Hemispheric Infarction

Cell-Type-Specific Profiling of Alternative Translation Identifies Regulated Protein Isoform Variation in the Mouse Brain

Characterization of a brain permeant fluorescent molecule and visualization of Aβ parenchymal plaques, using real-time multiphoton imaging in transgenic mice

Characterization of cis-regulatory elements of the vascular endothelial growth inhibitor gene promoter

Climbing STAIRs towards clinical trials with a novel PARP-1 inhibitor for the treatment of ischemic stroke.

Clinically relevant reperfusion in acute ischemic stroke: MTT performs better than Tmax and TTP.

Combination therapy for ischemic stroke: potential of neuroprotectants plus thrombolytics.

Defining the ischemic penumbra using hyperacute neuroimaging: deriving quantitative ischemic thresholds

Developing biomarkers for cerebral amyloid angiopathy trials: do potential disease phenotypes hold promise? - authors' reply

Does the white matter matter in Alzheimer disease and cerebral amyloid angiopathy?

Early Changes of Tissue Perfusion After Tissue Plasminogen Activator in Hyperacute Ischemic Stroke ⬇️

Enhanced Detection of Edema in Malignant Anterior Circulation Stroke (EDEMA) Score: A Risk Prediction Tool

Enhancing astrocytic lysosome biogenesis facilitates Aβ clearance and attenuates amyloid plaque pathogenesis

Expression profiling identifies a molecular signature of reactive astrocytes stimulated by cyclic AMP or proinflammatory cytokines

Final Results of the RHAPSODY Trial: A Multi-Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A-APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen

Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer's Disease

GISCOME - Genetics of Ischaemic Stroke Functional Outcome network: A protocol for an international multicentre genetic association study

Genetic Imbalance Is Associated With Functional Outcome After Ischemic Stroke

Genetic variants associated with Alzheimer's disease confer different cerebral cortex cell-type population structure.

Genetic variation at 16q24.2 is associated with small vessel stroke

Genetically Determined Levels of Circulating Cytokines and Risk of Stroke

Hospital case-volume is associated with case-fatality after aneurysmal subarachnoid hemorrhage

Identification of novel brain biomarkers.

Interaction of cardiac implantable electronic device and patent foramen ovale in ischemic stroke: A case-only study

Intravenous fibrinolysis eligibility: a survey of stroke clinicians' practice patterns and review of the literature

JNK activation contributes to DP5 induction and apoptosis following traumatic spinal cord injury.

Lacunes: Black holes in our understanding of cerebral amyloid angiopathy.

Large-Vessel Vasculopathy in Children With Sickle Cell Disease: A Magnetic Resonance Imaging Study of Infarct Topography and Focal Atrophy

Low-density lipoprotein receptor-related protein 1 (LRP1) mediates neuronal Abeta42 uptake and lysosomal trafficking

Magnetic resonance cerebral metabolic rate of oxygen utilization in hyperacute stroke patients

Matrix metalloproteinase-9 and spontaneous hemorrhage in an animal model of cerebral amyloid angiopathy

Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ

Matrix metalloproteinase-9 in cerebral-amyloid-angiopathy-related hemorrhage

Matrix metalloproteinases expressed by astrocytes mediate extracellular amyloid-beta peptide catabolism.

Methylprednisolone protects oligodendrocytes but not neurons after spinal cord injury

Multifocal stroke with proliferation of small cerebral arteries in hepatopulmonary syndrome

Multisensory stimulation improves functional recovery and resting-state functional connectivity in the mouse brain after stroke.

Neurologic and neuroimaging manifestations of Cantú syndrome: A case series ⬇️

Neuronal activity regulates the regional vulnerability to amyloid-β deposition ⬇️

Neuronal apoptosis after CNS injury: the roles of glutamate and calcium.

Neuronal-Targeted TFEB Accelerates Lysosomal Degradation of APP, Reducing Aβ Generation and Amyloid Plaque Pathogenesis

Noncoding RNAs in Cardiovascular Disease: Current Knowledge, Tools and Technologies for Investigation, and Future Directions: A Scientific Statement From the American Heart Association

Noninvasive detection of brainstem and spinal cord axonal degeneration in an amyotrophic lateral sclerosis mouse model ⬇️

Oligodendrocyte degeneration and recovery after focal cerebral ischemia.

Outcome markers for clinical trials in cerebral amyloid angiopathy

Oxygen metabolism in ischemic stroke using magnetic resonance imaging.

PATJ Low Frequency Variants Are Associated With Worse Ischemic Stroke Functional Outcome

Patent foramen ovale and stroke: Should PFOs be closed in otherwise cryptogenic stroke?

Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network

Pathophysiology of Brain Ischemia

Personalizing acute therapies for ischemic stroke: Thrombolysis or thrombectomy?

Photo-activatable Cre recombinase regulates gene expression in vivo

Preexisting Statin Use Is Associated With Greater Reperfusion in Hyperacute Ischemic Stroke ⬇️

Protein phosphatase 2A regulates bim expression via the Akt/FKHRL1 signaling pathway in amyloid-beta peptide-induced cerebrovascular endothelial cell death.

RP11-362K2.2:RP11-767I20.1 Genetic Variation Is Associated with Post-Reperfusion Therapy Parenchymal Hematoma. A GWAS Meta-Analysis

Rapid perfusion abnormality estimation in acute stroke with temporal correlation analysis

Red cell exchange transfusions lower cerebral blood flow and oxygen extraction fraction in pediatric sickle cell anemia.

Reducing Door-to-Needle Times Using Toyota’s Lean Manufacturing Principles and Value Stream Analysis ⬇️

Refractory giant cell arteritis with spinal cord infarction

Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease

Remote Limb Ischemic Conditioning and Motor Learning: Evaluation of Factors Influencing Response in Older Adults

Remote Limb Ischemic Conditioning at Two Cuff Inflation Pressures Yields Learning Enhancements in Healthy Adults.

Remote limb ischemic conditioning enhances motor learning in healthy humans.

Reperfusion Beyond 6 Hours Reduces Infarct Probability in Moderately Ischemic Brain Tissue

Resident-based acute stroke protocol is expeditious and safe.

Role of phosphatidylinositol clathrin assembly lymphoid-myeloid leukemia (PICALM) in intracellular amyloid precursor protein (APP) processing and amyloid plaque pathogenesis

Sensory deprivation after focal ischemia in mice accelerates brain remapping and improves functional recovery through Arc-dependent synaptic plasticity.