List of works - Alina Ghinet

A Small Aromatic Compound Has Antifungal Properties and Potential Anti-Inflammatory Effects against Intestinal Inflammation ⬇️

scientific article published on 14 January 2019

A sustainable approach to manage metal-contaminated soils: a preliminary greenhouse study for the possible production of metal-enriched ryegrass biomass for biosourced catalysts

scientific article published on 09 September 2019

Access to 3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species: a new family of potent farnesyltransferase inhibitors

scientific article published on 01 March 2019

An efficient one-pot reaction for the synthesis of pyrazolones bearing a phenothiazine unit

Antagonists of the P2X7 receptor: mechanism of enantioselective recognition using highly sulfated and sulfobutylether cyclodextrins by capillary electrokinetic chromatography

scientific article published on 18 July 2014

Antioxidant Activity of New Benzo[de]quinolines and Lactams: 2DQuantitative Structure-Activity Relationships

scientific article published on 01 September 2012

Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.

scientific article published on 4 December 2014

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

scientific article published on 24 May 2016

Discovery of ferrocene-containing farnesyltransferase inhibitors. Investigation of bulky lipophilic groups for the A2 binding site of farnesyltransferase

Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events.

scientific article

Eaton's reagent-mediated domino π-cationic arylations of aromatic carboxylic acids to Iasi-red polymethoxylated polycyclic aromatic hydrocarbons: products with unprecedented biological activities as tubulin polymerization inhibitors.

scientific article

Enantioseparation of pyroglutamide derivatives on polysaccharide based chiral stationary phases by high-performance liquid chromatography and supercritical fluid chromatography: a comparative study

scientific article published on 4 July 2014

Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands

scientific article published on 30 January 2020

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

scientific article published on 09 February 2015

Exploring chiral separation of 3-carboxamido-5-aryl isoxazole derivatives by supercritical fluid chromatography on amylose and cellulose tris dimethyl- and chloromethyl phenylcarbamate polysaccharide based stationary phases

scientific article

Exploring isoxazoles and pyrrolidinones decorated with the 4,6-dimethoxy-1,3,5-triazine unit as human farnesyltransferase inhibitors

scientific article published on 04 April 2019

From Conventional Lewis Acids to Heterogeneous Montmorillonite K10, Eco-friendly Plant-based Catalysts used as Green Lewis Acids

scientific article published on 6 February 2018

Impact of Functional Groups on the Copper-Initiated N-Arylation of 5-Functionalized Pyrrolidin-2-ones and Their Vinylogues

In Vitro Metabolism of Phenstatin: Potential Pharmacological Consequences ⬇️

scientific article published on August 1, 2011

Involvement of the P2X7 purinergic receptor in inflammation: an update of antagonists series since 2009 and their promising therapeutic potential.

scientific article

Methylene versus carbonyl bridge in the structure of new tubulin polymerization inhibitors with tricyclic A-rings.

scientific article published on 26 September 2016

New Efficient Eco-Friendly Supported Catalysts for the Synthesis of Amides with Antioxidant and Anti-Inflammatory Properties

scientific article published on 12 February 2020

New farnesyltransferase inhibitors in the phenothiazine series.

scientific article

New indolizine-chalcones as potent inhibitors of human farnesyltransferase: Design, synthesis and biological evaluation

scientific article

New salicylic acid and pyroglutamic acid conjugated derivatives confer protection to bread wheat against Zymoseptoria tritici

scientific article published on 30 October 2018

Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase

scientific article published on 22 October 2014

On the discovery of new potent human farnesyltransferase inhibitors: emerging pyroglutamic derivatives

scientific article

On the synthesis and biological properties of isocombretastatins: a case of ketone homologation during Wittig reaction attempts

scholarly article in RSC Advances, vol. 3 no. 11, 2013

Peptide chemistry applied to a new family of phenothiazine-containing inhibitors of human farnesyltransferase

scientific article

Performance comparison of chlorinated chiral stationary phases in supercritical fluid chromatography for separation of selected pyrrolidone derivatives

scientific article published on 05 March 2019

Phenothiazine-based CaaX competitive inhibitors of human farnesyltransferase bearing a cysteine, methionine, serine or valine moiety as a new family of antitumoral compounds.

scientific article

Phenyliodine(III) Diacetate/I2 -Mediated Domino Approach for Pyrrolo[1,4]Thiazines and 1,4-Thiazines by a One-Pot Morin Rearrangement of N,S-Acetals

scientific article published on 08 April 2019

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

scientific article published on 27 September 2019

Removal of heavy metals from contaminated water using industrial wastes containing calcium and magnesium

scientific article published in 2022

Separations of antifungal compounds in capillary electrophoresis with two anionic cyclodextrins

scientific article published on 22 March 2019

Studies on Pyrrolidinones: Chemistry of Dimethoxytriazines

Studies on indolizines. Evaluation of their biological properties as microtubule-interacting agents and as melanoma targeting compounds.

scientific article

Studies on phenothiazines: New microtubule-interacting compounds with phenothiazine A-ring as potent antineoplastic agents.

scientific article published on April 2016

Studies on pyrrolidinones. On the application of copper-catalyzed arylation of methyl pyroglutamate to obtain a new benzo[de]quinoline scaffold

Studies on pyrrolidinones. Reaction of pyroglutamic acid and vinylogues with aromatics in Eaton’s reagent

Supercritical fluid chromatography approach for a sustainable manufacture of new stereoisomeric anticancer agent

scientific article published on 10 August 2017

Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents

scientific article

Synthesis and biological evaluation of a new class of triazin–triazoles as potential inhibitors of human farnesyltransferase

Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors.

scientific article

Synthesis and biological evaluation of a new series of phenothiazine-containing protein farnesyltransferase inhibitors

scientific article published on 14 November 2012

Synthesis and biological evaluation of fluoro analogues of antimitotic phenstatin

scientific article published on 4 April 2013

Synthesis and biological evaluation of new phenothiazine derivatives bearing a pyrazole unit as protein farnesyltransferase inhibitors.

scientific article

Synthesis and biological evaluation of phenstatin metabolites

scientific article published on 27 August 2011

Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents.

scientific article published on 22 March 2016

The Reactivity of Enantiopure (S )-6-Oxopipecolic Acid and Corresponding Pyridoisoquinolines Under Acidic Conditions

The potential of ryegrass (Lolium perenne L.) to clean up multi-contaminated soils from labile and phytoavailable potentially toxic elements to contribute into a circular economy

scientific article published on 24 April 2019

The revisited synthesis of tert-butyl pyroglutamate derivatives

Toward a New Way for the Valorization of Miscanthus Biomass Produced on Metal-Contaminated Soils Part 1: Mesocosm and Field Experiments

scientific article published in 2020

List of works by Alina Ghinet

A Small Aromatic Compound Has Antifungal Properties and Potential Anti-Inflammatory Effects against Intestinal Inflammation ⬇️

A sustainable approach to manage metal-contaminated soils: a preliminary greenhouse study for the possible production of metal-enriched ryegrass biomass for biosourced catalysts

Access to 3-spiroindolizines containing an isoindole ring through intra-molecular arylation of spiro-N-acyliminium species: a new family of potent farnesyltransferase inhibitors

An efficient one-pot reaction for the synthesis of pyrazolones bearing a phenothiazine unit

Antagonists of the P2X7 receptor: mechanism of enantioselective recognition using highly sulfated and sulfobutylether cyclodextrins by capillary electrokinetic chromatography

Antioxidant Activity of New Benzo[de]quinolines and Lactams: 2DQuantitative Structure-Activity Relationships

Conformational Restriction Leading to a Selective CB2 Cannabinoid Receptor Agonist Orally Active Against Colitis.

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

Discovery of ferrocene-containing farnesyltransferase inhibitors. Investigation of bulky lipophilic groups for the A2 binding site of farnesyltransferase

Discovery of indolizines containing triazine moiety as new leads for the development of antitumoral agents targeting mitotic events.

Eaton's reagent-mediated domino π-cationic arylations of aromatic carboxylic acids to Iasi-red polymethoxylated polycyclic aromatic hydrocarbons: products with unprecedented biological activities as tubulin polymerization inhibitors.

Enantioseparation of pyroglutamide derivatives on polysaccharide based chiral stationary phases by high-performance liquid chromatography and supercritical fluid chromatography: a comparative study

Enhanced antitumor potential induced by chloroacetate-loaded benzophenones acting as fused tubulin-pyruvate dehydrogenase kinase 1 (PDHK1) ligands

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

Exploring chiral separation of 3-carboxamido-5-aryl isoxazole derivatives by supercritical fluid chromatography on amylose and cellulose tris dimethyl- and chloromethyl phenylcarbamate polysaccharide based stationary phases

Exploring isoxazoles and pyrrolidinones decorated with the 4,6-dimethoxy-1,3,5-triazine unit as human farnesyltransferase inhibitors

From Conventional Lewis Acids to Heterogeneous Montmorillonite K10, Eco-friendly Plant-based Catalysts used as Green Lewis Acids

Impact of Functional Groups on the Copper-Initiated N-Arylation of 5-Functionalized Pyrrolidin-2-ones and Their Vinylogues

In Vitro Metabolism of Phenstatin: Potential Pharmacological Consequences ⬇️

Involvement of the P2X7 purinergic receptor in inflammation: an update of antagonists series since 2009 and their promising therapeutic potential.

Methylene versus carbonyl bridge in the structure of new tubulin polymerization inhibitors with tricyclic A-rings.

New Efficient Eco-Friendly Supported Catalysts for the Synthesis of Amides with Antioxidant and Anti-Inflammatory Properties

New farnesyltransferase inhibitors in the phenothiazine series.

New indolizine-chalcones as potent inhibitors of human farnesyltransferase: Design, synthesis and biological evaluation

New salicylic acid and pyroglutamic acid conjugated derivatives confer protection to bread wheat against Zymoseptoria tritici

Novel indolizine derivatives with unprecedented inhibitory activity on human farnesyltransferase

On the discovery of new potent human farnesyltransferase inhibitors: emerging pyroglutamic derivatives

On the synthesis and biological properties of isocombretastatins: a case of ketone homologation during Wittig reaction attempts

Peptide chemistry applied to a new family of phenothiazine-containing inhibitors of human farnesyltransferase

Performance comparison of chlorinated chiral stationary phases in supercritical fluid chromatography for separation of selected pyrrolidone derivatives

Phenothiazine-based CaaX competitive inhibitors of human farnesyltransferase bearing a cysteine, methionine, serine or valine moiety as a new family of antitumoral compounds.

Phenyliodine(III) Diacetate/I2 -Mediated Domino Approach for Pyrrolo[1,4]Thiazines and 1,4-Thiazines by a One-Pot Morin Rearrangement of N,S-Acetals

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

Removal of heavy metals from contaminated water using industrial wastes containing calcium and magnesium

Separations of antifungal compounds in capillary electrophoresis with two anionic cyclodextrins

Studies on Pyrrolidinones: Chemistry of Dimethoxytriazines

Studies on indolizines. Evaluation of their biological properties as microtubule-interacting agents and as melanoma targeting compounds.

Studies on phenothiazines: New microtubule-interacting compounds with phenothiazine A-ring as potent antineoplastic agents.

Studies on pyrrolidinones. On the application of copper-catalyzed arylation of methyl pyroglutamate to obtain a new benzo[de]quinoline scaffold

Studies on pyrrolidinones. Reaction of pyroglutamic acid and vinylogues with aromatics in Eaton’s reagent

Supercritical fluid chromatography approach for a sustainable manufacture of new stereoisomeric anticancer agent

Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents

Synthesis and biological evaluation of a new class of triazin–triazoles as potential inhibitors of human farnesyltransferase

Synthesis and biological evaluation of a new series of N-ylides as protein farnesyltransferase inhibitors.

Synthesis and biological evaluation of a new series of phenothiazine-containing protein farnesyltransferase inhibitors

Synthesis and biological evaluation of fluoro analogues of antimitotic phenstatin

Synthesis and biological evaluation of new phenothiazine derivatives bearing a pyrazole unit as protein farnesyltransferase inhibitors.

Synthesis and biological evaluation of phenstatin metabolites

Synthesis of triazoloquinazolinone based compounds as tubulin polymerization inhibitors and vascular disrupting agents.

The Reactivity of Enantiopure (S )-6-Oxopipecolic Acid and Corresponding Pyridoisoquinolines Under Acidic Conditions

The potential of ryegrass (Lolium perenne L.) to clean up multi-contaminated soils from labile and phytoavailable potentially toxic elements to contribute into a circular economy

The revisited synthesis of tert-butyl pyroglutamate derivatives

Toward a New Way for the Valorization of Miscanthus Biomass Produced on Metal-Contaminated Soils Part 1: Mesocosm and Field Experiments