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List of works by David J Waugh

A peptide from the caudal neurosecretory system of the dogfish Scyliorhinus canicula that is structurally related to urotensin I

scientific article published on 01 September 1995

ACE: A Workbench using Evolutionary Genetic Algorithms for analysing association in TCGA Data

Androgen deprivation results in time-dependent hypoxia in LNCaP prostate tumours: informed scheduling of the bioreductive drug AQ4N improves treatment response.

scientific article published on 23 November 2012

Androgens and estrogens stimulate ribosome biogenesis in prostate and breast cancer cells in receptor dependent manner.

scientific article published on 19 April 2013

CD44 increases the efficiency of distant metastasis of breast cancer

scientific article published on May 2015

CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells

scientific article published on 01 August 2004

CD44-mediated activation of α5β1-integrin, cortactin and paxillin signaling underpins adhesion of basal-like breast cancer cells to endothelium and fibronectin-enriched matrices.

scientific article published on 2 October 2015

Challenging the Cancer Molecular Stratification Dogma: Intratumoral Heterogeneity Undermines Consensus Molecular Subtypes and Potential Diagnostic Value in Colorectal Cancer.

scientific article published on 5 May 2016

Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis.

scientific article published on 9 September 2008

Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer ⬇️

scientific article published on May 9, 2012

Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists

scientific article published on 22 October 2018

Delivering a research-enabled multistakeholder partnership for enhanced patient care at a population level: The Northern Ireland Comprehensive Cancer Program

scientific article published on 22 December 2015

Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function.

scientific article published in August 2013

Expanding the Armamentarium for Castrate-resistant Prostate Cancer.

scientific article

FKBPL and peptide derivatives: novel biological agents that inhibit angiogenesis by a CD44-dependent mechanism.

scientific article

Growth inhibitory activity of extracted material and isolated compounds from the fruits of Kigelia pinnata.

scientific article published on 17 June 2010

HIF-1 and NF-kappaB-mediated upregulation of CXCR1 and CXCR2 expression promotes cell survival in hypoxic prostate cancer cells

scientific article published on 28 May 2007

Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity.

scientific article published in June 2003

Modulating the unfolded protein response with ONC201 to impact on radiation response in prostate cancer cells

scientific article published on 19 February 2021

Molecular Subgroup of Primary Prostate Cancer Presenting with Metastatic Biology.

scientific article published on 10 April 2017

Novel aromatic residues in transmembrane domains IV and V involved in agonist binding at alpha(1a)-adrenergic receptors

scientific article published on 01 April 2000

PTEN deficiency promotes macrophage infiltration and hypersensitivity of prostate cancer to IAP antagonist/radiation combination therapy.

scientific article published on 20 January 2016

PTEN mRNA detection by chromogenic, RNA in situ technologies: a reliable alternative to PTEN immunohistochemistry

scientific article published on 25 September 2015

Potentiation of inflammatory CXCL8 signalling sustains cell survival in PTEN-deficient prostate carcinoma.

scientific article

Protocols for Studies on Genetically Engineered Mouse Models in Prostate Cancer

scientific article published on 01 January 2018

Rationale and Means to Target Pro-Inflammatory Interleukin-8 (CXCL8) Signaling in Cancer.

scientific article published on 06 August 2013

Regulation of the cellular localization and signaling properties of the alpha(1B)- and alpha(1D)-adrenoceptors by agonists and inverse agonists.

scientific article published on April 2000

Structure-activity studies on position 14 of human alpha-calcitonin gene-related peptide.

scientific article published in September 1997

Synthesis and in vitro and in vivo evaluation of a series of dihydroisocoumarin derivatives conjugated with fatty acids, alcohols, and amines as potential anticancer agents.

scientific article

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities

scientific article

Tachykinins with unusual structural features from a urodele, the amphiuma, an elasmobranch, the hammerhead shark, and an agnathan, the river lamprey

scientific article published on 01 January 1995

The Agonism and Synergistic Potentiation of Weak Partial Agonists by Triethylamine in α1-Adrenergic Receptor Activation: Evidence for a Salt Bridge as the Initiating Process ⬇️

scientific article published on April 1, 1998

The emerging role of CD44 in regulating skeletal micrometastasis.

scientific article

The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue ⬇️

scientific article published on February 1, 2011

The interleukin-8 pathway in cancer.

scientific article

The prognostic value of the stem-like group in colorectal cancer using a panel of immunohistochemistry markers

scientific article published in May 2015

Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells.

scientific article

Urotensin II in the Central Nervous System of the Frog Rana ridibunda: Biochemical Characterization and Immunohistochemical Localizationa ⬇️

scientific article published on May 15, 1998

Urotensin II in the central nervous system of the frog Rana ridibunda: immunohistochemical localization and biochemical characterization

scientific article published on 01 January 1996

Validation of a Metastatic Assay using biopsies to improve risk stratification in patients with prostate cancer treated with radical radiation therapy.

scientific article

Validation of next generation sequencing technologies in comparison to current diagnostic gold standards for BRAF, EGFR and KRAS mutational analysis

scientific article

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