Search filters

List of works by Donald J Buchsbaum

18F-2-deoxy-2-fluoro-D-glucose uptake into human tumor xenografts. Feasibility studies for cancer imaging with positron-emission tomography

scientific article published on 01 March 1991

212Pb-Labeled Antibody 225.28 Targeted to Chondroitin Sulfate Proteoglycan 4 for Triple-Negative Breast Cancer Therapy in Mouse Models.

scientific article

212Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models

scientific article published on 24 December 2017

A Novel Imaging Biomarker Extracted from Fluorescence Microscopic Imaging of TRA-8/DR5 Oligomers Predicts TRA-8 Therapeutic Efficacy in Breast and Pancreatic Cancer Mouse Models.

scientific article published on 9 November 2015

A mouse bone marrow dosimetry model ⬇️

scientific article published on July 1, 1998

A peptide-based bifunctional chelating agent for 99mTc- and 186Re-labeling of monoclonal antibodies

scientific article published on 01 February 1994

A phase I study evaluating the role of the anti-epidermal growth factor receptor (EGFR) antibody cetuximab as a radiosensitizer with chemoradiation for locally advanced pancreatic cancer.

scientific article

A quantitative study of radionuclide characteristics for radioimmunotherapy from 3D reconstructions using serial autoradiography

scientific article published on 01 April 1996

A review of B7-H3 and B7-H4 immune molecules and their role in ovarian cancer.

scientific article published on 19 August 2012

A robust summarize-regress procedure for tissue-specific pharmacokinetics

scientific article published on 01 May 2000

A sensitivity study of micro-TLDs for in vivo dosimetry of radioimmunotherapy.

scientific article published in November 1991

Altered expression of 15-hydroxyprostaglandin dehydrogenase in tumor-infiltrated CD11b myeloid cells: a mechanism for immune evasion in cancer.

scientific article

Antagonistic effects of anti-EMMPRIN antibody when combined with chemotherapy against hypovascular pancreatic cancers.

scientific article

Anti-EMMPRIN monoclonal antibody as a novel agent for therapy of head and neck cancer.

scientific article published on 09 June 2009

Anti-tumor activity of an anti-DR5 monoclonal antibody, TRA-8, in combination with taxane/platinum-based chemotherapy in an ovarian cancer model.

scientific article published on 5 January 2011

Antitumor efficacy of TRA-8 anti-DR5 monoclonal antibody alone or in combination with chemotherapy and/or radiation therapy in a human breast cancer model ⬇️

scientific article published on September 1, 2003

Antitumor efficacy of capecitabine and celecoxib in irradiated and lead-shielded, contralateral human BxPC-3 pancreatic cancer xenografts: clinical implications of abscopal effects.

scientific article published in December 2005

B7-H3-targeted 212Pb radioimmunotherapy of ovarian cancer in preclinical models

scientific article published on 10 January 2017

Brief overview of preclinical and clinical studies in the development of intraperitoneal radioimmunotherapy for ovarian cancer.

scientific article published on September 2007

CD38 pretargeted RIT of B-cell tumors.

scientific article published in February 2018

CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.

scientific article

Calmodulin Binding to Death Receptor 5-mediated Death-Inducing Signaling Complex in Breast Cancer Cells.

scientific article published on 16 January 2017

Calmodulin antagonist enhances DR5-mediated apoptotic signaling in TRA-8 resistant triple negative breast cancer cells

scientific article published on 16 April 2018

Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers

scientific article published on 24 July 2013

Cellular model of Warburg effect identifies tumor promoting function of UCP2 in breast cancer and its suppression by genipin

scientific article

Characterization of the Interactions between Calmodulin and Death Receptor 5 in Triple-negative and Estrogen Receptor-positive Breast Cancer Cells: AN INTEGRATED EXPERIMENTAL AND COMPUTATIONAL STUDY.

scientific article published on 22 April 2016

Combination of cytosine deaminase suicide gene expression with DR5 antibody treatment increases cancer cell cytotoxicity.

scientific article

Combination therapy with anti-DR5 antibody and tamoxifen for triple negative breast cancer.

scientific article

Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer

scientific article

Combined ionizing radiation and sKDR gene delivery for treatment of prostate carcinomas.

scientific article

Combined modality therapy of A431 human epidermoid cancer using anti-EGFr antibody C225 and radiation

scientific article published on 01 December 1999

Combined modality therapy with TRAIL or agonistic death receptor antibodies.

scientific article published on March 2011

Comparison of 131I- and 90Y-labeled monoclonal antibody 17-1A for treatment of human colon cancer xenografts

scientific article published on 01 March 1993

Comparison of the distribution and binding of monoclonal antibodies labeled with 131-iodine or 111-indium

scholarly article by Donald J Buchsbaum et al published 1 January 1985 in European Journal of Nuclear Medicine and Molecular Imaging

Conjugation of unprotected trisuccin, N-[tris[2-[(N-hydroxyamino)carbonyl]ethyl]methyl]succinamic acid, to monoclonal antibody CC49 by an improved active ester protocol

scientific article published on 01 September 1997

Correction: Niclosamide and its analogs are potent inhibitors of Wnt/β-catenin, mTOR and STAT3 signaling in ovarian cancer.

scientific article published on 10 April 2018

Corrigendum to '212Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models' [Nucl Med Biol 58 (2018) 67-73]

scientific article published on 25 April 2018

DCE-MRI detects early vascular response in breast tumor xenografts following anti-DR5 therapy

scientific article

Dosimetric comparison of bolus and continuous injections of CC49 monoclonal antibody in a colon cancer xenograft model ⬇️

scientific article published on December 15, 1997

Dynamic contrast enhanced magnetic resonance imaging of an orthotopic pancreatic cancer mouse model

scientific article

Effect of anti-DR5 and chemotherapy on basal-like breast cancer ⬇️

scientific article published on September 7, 2011

Effect of backscatter on cell survival for a clinical electron beam.

scientific article published on August 1991

Effect of niclosamide on basal-like breast cancers

scientific article published on 19 February 2014

Effect of rat tumor allografts on the blood level of passively transferred alloantibodies

Enhanced apoptosis following treatment with TRA-8 anti-human DR5 monoclonal antibody and overexpression of exogenous Bax in human glioma cells.

scientific article published on April 2004

Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth

scientific article published on 24 April 2017

Epigenetic therapy for the treatment of epithelial ovarian cancer: A clinical review

scientific article published on 21 March 2017

ErbB3 expression and dimerization with EGFR influence pancreatic cancer cell sensitivity to erlotinib.

scientific article published on April 2007

Experimental tumor targeting with radiolabeled ligands ⬇️

scientific article published on December 15, 1997

Further studies on the protein conjugation of hydroxamic acid bifunctional chelating agents: group-specific conjugation at two different loci.

scientific article

Gene expression imaging with radiolabeled peptides.

scientific article published in June 2004

Genetically designing a more potent antipancreatic cancer agent by simultaneously co-targeting human IL13 and EGF receptors in a mouse xenograft model.

scientific article published on 25 January 2008

Genomic regulation of invasion by STAT3 in triple negative breast cancer.

scientific article published on 24 December 2016

Glycosyltransferase ST6Gal-I promotes the epithelial to mesenchymal transition in pancreatic cancer cells

scientific article published on 04 November 2020

High-resolution single-photon emission computed tomography and X-ray computed tomography imaging of Tc-99m-labeled anti-DR5 antibody in breast tumor xenografts.

scientific article published in March 2007

Histone deacetylase inhibition promotes intratumoral CD8+ T-cell responses, sensitizing murine breast tumors to anti-PD1

scientific article published on 12 November 2019

Human leukemia cell binding and killing by anti-CD5 radioimmunotoxins.

scientific article

Immunohistochemistry in the evaluation of neovascularization in tumor xenografts

scientific article published on June 2008

Improved synthesis of the bifunctional chelating agent 1,4,7,10-tetraaza-N-(1-carboxy-3-(4-nitrophenyl)propyl)-N',N'',N'''-tri s(acetic acid)cyclododecane (PA-DOTA)

scientific article published on 01 November 1999

In vivo efficacy of marimastat and chemoradiation in head and neck cancer xenografts

scientific article published on 16 October 2008

Inducible resistance of tumor cells to tumor necrosis factor-related apoptosis-inducing ligand receptor 2-mediated apoptosis by generation of a blockade at the death domain function.

scientific article published on September 2006

Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer.

scientific article published on 13 April 2014

Introduction: radiolabeled antibody tumor dosimetry.

scientific article

Journey of TRAIL from Bench to Bedside and its Potential Role in Immuno-Oncology.

scientific article published on March 2017

KISS1 over-expression suppresses metastasis of pancreatic adenocarcinoma in a xenograft mouse model ⬇️

scientific article published on September 16, 2010

Localization of Radiolabeled Antibody in SVT2 Tumor Increases with Immunosuppression of the Host ⬇️

scientific article published on 01 October 1982

Localization of an 125I-Labeled Rat Transplantation Antibody in Tumors Carrying the Corresponding Antigen

Localization of iodine-125-mIP-Des-Met14-bombesin (7-13)NH2 in ovarian carcinoma induced to express the gastrin releasing peptide receptor by adenoviral vector-mediated gene transfer ⬇️

scientific article published on 01 August 1997

Loss of tumor suppressor Merlin results in aberrant activation of Wnt/β-catenin signaling in cancer

scientific article published on 19 February 2016

Lung resistance-related protein (LRP) expression in malignant ascitic cells as a prognostic marker for advanced ovarian serous carcinoma.

scientific article published on 24 March 2013

Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells.

scientific article

Mechanisms of resistance to Erbitux (anti-epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells.

scientific article

Modulation of antitumor immunity with histone deacetylase inhibitors.

scientific article published in December 2017

Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo ⬇️

scientific article published on October 1, 1997

Molecular chemotherapy of pancreatic cancer using novel mutant bacterial cytosine deaminase gene.

scientific article published on September 2008

Molecular targeted approaches for treatment of pancreatic cancer.

scientific article

Monoclonal antibodies in the treatment of pancreatic cancer.

scientific article published on March 2009

Monoclonal antibody-based immunotherapy of ovarian cancer: targeting ovarian cancer cells with the B7-H3-specific mAb 376.96.

scientific article published on 9 November 2013

Multi-targeted therapy of cancer by niclosamide: A new application for an old drug.

scientific article

Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma

scientific article published on February 2006

Niclosamide Analogs for Treatment of Ovarian Cancer

scientific article published on 16 July 2015

Novel Biomimetic Microphysiological Systems for Tissue Regeneration and Disease Modeling

scientific article published on 01 January 2018

Ovarian and cervical cancer patient derived xenografts: The past, present, and future.

scientific article published on 27 May 2015

Ovarian cancer and the immune system - The role of targeted therapies.

scientific article published on 9 May 2016

Overcoming TRAIL resistance in ovarian carcinoma

scientific article published on 16 July 2010

Paclitaxel derivatives for targeted therapy of cancer: toward the development of smart taxanes.

scientific article

Pazopanib combined with radiation: in vivo model of interaction.

scientific article

Preclinical studies and clinical utilization of monoclonal antibodies in epithelial ovarian cancer.

scientific article published on 20 February 2009

Preferential Inhibition of Wnt/β-Catenin Signaling by Novel Benzimidazole Compounds in Triple-Negative Breast Cancer.

scientific article

Pretargeted radioimmunotherapy

scientific article published on 01 January 2006

Progress in Cancer Therapy ⬇️

scientific article published on January 10, 2012

RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4

scientific article published on 26 May 2016

Radioiodination of monoclonal antibodies D612 and 17-1A with 3-iodophenylisothiocyanate and their biodistribution in tumor-bearing nude mice

scientific article published on 01 February 1994

Radiosensitization mediated by a transfected anti-erbB-2 single-chain antibody in vitro and in vivo

scientific article published on 01 November 1998

Recurrent read-through fusion transcripts in breast cancer

scientific article

Relationship between galectin-3 expression and TRAIL sensitivity in breast cancer

scientific article published on 01 August 2011

Retraction notice to "SRI36160 is a specific inhibitor of Wnt/<beta>-catenin signaling in human pancreatic and colorectal cancer cells" [Canc. Lett. 389C (2017) 41-48].

scientific article published in May 2018

Role of nanotechnology and gene delivery systems in TRAIL-based therapies

scientific article

S100A4 promotes pancreatic cancer progression through a dual signaling pathway mediated by Src and focal adhesion kinase.

scientific article

SPARC-Independent Delivery of Nab-Paclitaxel without Depleting Tumor Stroma in Patient-Derived Pancreatic Cancer Xenografts

scientific article published on February 2016

SRI36160 is a specific inhibitor of Wnt/β-catenin signaling in human pancreatic and colorectal cancer cells

scientific article published on 30 December 2016

ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines.

scientific article published on 28 January 2013

ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage.

scientific article published on 30 November 2017

STAT3 and GR cooperate to drive gene expression and growth of basal-like triple-negative breast cancer

scientific article published on 19 August 2020

Sensitization of radiolabeled monoclonal antibody therapy using bromodeoxyuridine

scientific article published on 01 February 1994

Simultaneous evaluation of dual gene transfer to adherent cells by gamma-ray imaging.

scientific article published on February 2001

Site-specifically traced drug release and biodistribution of a paclitaxel-antibody conjugate toward improvement of the linker structure.

scientific article

Surveying the serologic proteome in a tissue-specific kras(G12D) knockin mouse model of pancreatic cancer

scientific article published on 17 November 2015

Synthesis and biodistribution of peptide based 99mTc/186Re-MAGIPG-D612 monoclonal antibody in nude mice bearing colon cancer xenografts

scientific article published on 01 February 1997

Synthesis and biological evaluation of paclitaxel-C225 conjugate as a model for targeted drug delivery.

scientific article published in March 2003

Synthesis of N-[tris[2-[[N-(benzyloxy)amino]carbonyl]ethyl]methyl]succinamic acid, trisuccin. Hydroxamic acid derivatives as a new class of bifunctional chelating agents

scientific article published on 01 May 1993

Synthesis of bombesin analogues for radiolabeling with rhenium‐188 ⬇️

scientific article published on December 15, 1997

Synthesis of the first diethylenetriaminepentahydroxamic acid (DTPH) bifunctional chelating agent.

scientific article published in March 2002

Synthesis, rhenium-188 labeling and biodistribution studies of a phenolic ester derivative of trisuccin

scientific article published on 01 December 1997

TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth.

scientific article published on December 2007

TRAIL receptor-targeted therapy.

scientific article published on August 2006

Targeted radiotherapy potentiates the cytotoxicity of a novel anti-human DR5 monoclonal antibody and the adenovirus encoding soluble TRAIL in prostate cancer

scientific article published on 15 September 2015

Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974.

scientific article

The C-terminal region Mesd peptide mimics full-length Mesd and acts as an inhibitor of Wnt/β-catenin signaling in cancer cells.

scientific article

The Tumor-Associated Glycosyltransferase ST6Gal-I Regulates Stem Cell Transcription Factors and Confers a Cancer Stem Cell Phenotype

scientific article

The Wnt/β-catenin pathway in ovarian cancer: a review.

scientific article published on 11 October 2013

The antitumor effects of entinostat in ovarian cancer require adaptive immunity

scientific article published on 13 November 2018

The expression of MHC class II molecules on murine breast tumors delays T-cell exhaustion, expands the T-cell repertoire, and slows tumor growth

scientific article published on 17 October 2018

The impact of novel retinoids in combination with platinum chemotherapy on ovarian cancer stem cells ⬇️

scientific article published on December 9, 2011

Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation.

scientific article published on 10 October 2008

Thrombospondin-1 opens the paracellular pathway in pulmonary microvascular endothelia through EGFR/ErbB2 activation.

scientific article

Treatment of small cell lung cancer with TRA-8 in combination with cisplatin and radiation ⬇️

scientific article published on June 30, 2011

Treatment with gemcitabine and TRA-8 anti-death receptor-5 mAb reduces pancreatic adenocarcinoma cell viability in vitro and growth in vivo.

scientific article published on November 2006

Tumor localization of a radiolabeled bombesin analogue in mice bearing human ovarian tumors induced to express the gastrin‐releasing peptide receptor by an adenoviral vector ⬇️

scientific article published on December 15, 1997

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers.

scientific article published on 29 June 2007

Use of a novel cross-linking method to modify adenovirus tropism ⬇️

scientific article published on December 1, 1997

Paulina is supported by:

About Paulina

Help