List of works - Erin Janssen

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.

scientific article

Adaptor proteins in lymphocyte activation.

scientific article

Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor 𝛋B kinase alpha (IKKα)

scientific article published on 17 September 2021

DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.

scientific article published on 5 October 2017

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

scientific article

Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells

scientific article

Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.

scientific article published on 17 October 2016

Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome

scientific article published on 25 March 2013

Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.

scientific article published on February 2013

Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis.

scientific article published on 31 December 2013

Flow cytometry diagnosis of dedicator of cytokinesis 8 (DOCK8) deficiency.

scientific article published in April 2014

Heterozygosity for transmembrane activator and calcium modulator ligand interactor A144E causes haploinsufficiency and pneumococcal susceptibility in mice

scientific article published on 5 September 2016

Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.

scientific article published on January 2003

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling

scientific article

Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis

scientific article

Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.

scientific article published on September 2002

Primary immunodeficiencies caused by mutations in actin regulatory proteins

scientific article published on 01 January 2019

Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA.

scientific article

WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis.

scientific article

List of works by Erin Janssen

A DOCK8-WIP-WASp complex links T cell receptors to the actin cytoskeleton.

Adaptor proteins in lymphocyte activation.

Combined immunodeficiency with autoimmunity caused by a homozygous missense mutation in inhibitor of nuclear factor 𝛋B kinase alpha (IKKα)

DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.

DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation

Dedicator of cytokinesis 8-deficient patients have a breakdown in peripheral B-cell tolerance and defective regulatory T cells

Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity.

Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome

Epicutaneous sensitization results in IgE-dependent intestinal mast cell expansion and food-induced anaphylaxis.

Flow cytometry biomarkers distinguish DOCK8 deficiency from severe atopic dermatitis.

Flow cytometry diagnosis of dedicator of cytokinesis 8 (DOCK8) deficiency.

Heterozygosity for transmembrane activator and calcium modulator ligand interactor A144E causes haploinsufficiency and pneumococcal susceptibility in mice

Minimal requirement of tyrosine residues of linker for activation of T cells in TCR signaling and thymocyte development.

Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling

Next-Generation Sequencing Reveals Restriction and Clonotypic Expansion of Treg Cells in Juvenile Idiopathic Arthritis

Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.

Primary immunodeficiencies caused by mutations in actin regulatory proteins

Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA.

WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis.