List of works - Joan Carles Escola-Gil

A Functional Virgin Olive Oil Enriched with Olive Oil and Thyme Phenolic Compounds Improves the Expression of Cholesterol Efflux-Related Genes: A Randomized, Crossover, Controlled Trial

scientific article published on 26 July 2019

APOA1 oxidation is associated to dysfunctional high-density lipoproteins in human abdominal aortic aneurysm.

scientific article published on 11 April 2019

ATP-binding cassette G5/G8 deficiency causes hypertriglyceridemia by affecting multiple metabolic pathways.

scientific article published on 10 August 2011

Acute Psychological Stress Accelerates Reverse Cholesterol Transport via Corticosterone-Dependent Inhibition of Intestinal Cholesterol Absorption ⬇️

scientific article published on August 28, 2012

Administration of CORM-2 inhibits diabetic neuropathy but does not reduce dyslipidemia in diabetic mice

scientific article published in PLoS ONE

Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy

scientific article published on 14 February 2020

Antiatherogenic role of high-density lipoproteins: insights from genetically engineered-mice

scientific article

ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer.

scientific article

Apolipoprotein Mimetics in Cancer

scientific article published on 11 November 2020

Are LXR-regulated genes a major molecular target of plant sterols/stanols?

scientific article published on 12 January 2007

CETP activity variation in mice does not affect two major HDL antiatherogenic properties: macrophage-specific reverse cholesterol transport and LDL antioxidant protection

scientific article published on 22 June 2007

Cholesterol and 27-hydroxycholesterol promote thyroid carcinoma aggressiveness

scientific article published on 16 July 2019

Cholesterol efflux and reverse cholesterol transport

scientific article

Chronic intermittent psychological stress promotes macrophage reverse cholesterol transport by impairing bile acid absorption in mice

scientific article

Chylomicrons: Advances in biology, pathology, laboratory testing, and therapeutics.

scientific article published on 08 February 2016

Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport

scientific article published on 07 September 2016

Cross-Talk between Inflammatory Mediators and the Epithelial Mesenchymal Transition Process in the Development of Thyroid Carcinoma.

scientific article

Dietary phytosterols modulate T-helper immune response but do not induce apparent anti-inflammatory effects in a mouse model of acute, aseptic inflammation

scientific article published on 01 March 2007

Differential effects of gemfibrozil and fenofibrate on reverse cholesterol transport from macrophages to feces in vivo.

scientific article published on 30 November 2010

Effects of Virgin Olive Oil and Phenol-Enriched Virgin Olive Oils on Lipoprotein Atherogenicity

scientific article published on 26 February 2020

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice.

scientific article

Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia

scientific article published on 01 August 2000

Free cholesterol deposition in the cornea of human apolipoprotein A-II transgenic mice with functional lecithin: cholesterol acyltransferase deficiency

scientific article published on 01 April 1999

Gene Variant and Level of IL-1β in Ischemic Stroke Patients With and Without Type 2 Diabetes Mellitus

scientific article

HDL and LDL: Potential New Players in Breast Cancer Development

scientific article published on 14 June 2019

HDL and lifestyle interventions

scientific article

Hepatic lipase- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT and HDL antioxidant properties.

scientific article published on 15 January 2013

Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.

scientific article published on 19 December 2017

Human ApoA-I Overexpression Enhances Macrophage-Specific Reverse Cholesterol Transport but Fails to Prevent Inherited Diabesity in Mice ⬇️

scientific article published on 02 February 2019

Human apolipoprotein A-II determines plasma triglycerides by regulating lipoprotein lipase activity and high-density lipoprotein proteome.

scientific article

Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential.

scientific article published on 23 September 2004

Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: evidence of a potentially relevant species-specific interaction with diet

scientific article published on 01 February 1998

Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake

scientific article published on 15 December 2017

Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake.

scientific article published on 2 December 2013

Identification and validation of common molecular targets of hydroxytyrosol

scientific article published on 24 July 2019

IgG Anti-High Density Lipoprotein Antibodies Are Elevated in Abdominal Aortic Aneurysm and Associated with Lipid Profile and Clinical Features

scientific article published on 26 December 2019

Impaired HDL (High-Density Lipoprotein)-Mediated Macrophage Cholesterol Efflux in Patients With Abdominal Aortic Aneurysm-Brief Report

scientific article published on 01 November 2018

LXR-dependent regulation of macrophage-specific reverse cholesterol transport is impaired in a model of genetic diabesity.

scientific article published on 18 May 2017

Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: "Herniated" HDL, a common feature in diabetes

scientific article published on 18 January 2016

Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.

scientific article published on 28 May 2008

Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity

scientific article published on 26 February 2020

Low-density lipoproteins from embryonic cerebrospinal fluid are required for neural differentiation

scientific article published on 01 September 2008

Macrophage Cholesterol Efflux Downregulation Is Not Associated with Abdominal Aortic Aneurysm (AAA) Progression

scientific article published on 24 April 2020

Manipulation of inflammation modulates hyperlipidemia in apolipoprotein E-deficient mice: A possible role for interleukin-6

scientific article published on 01 May 2006

Mast cell activation in vivo impairs the macrophage reverse cholesterol transport pathway in the mouse

scientific article published on 6 January 2011

Methionine-induced hyperhomocysteinemia impairs the antioxidant ability of high-density lipoproteins without reducing in vivo macrophage-specific reverse cholesterol transport.

scientific article published on 10 June 2013

Modulation of autoimmune arthritis severity in mice by apolipoprotein E (ApoE) and cholesterol.

scientific article published on 29 August 2016

Molecular Insights into the Mechanisms Underlying the Cholesterol- Lowering Effects of Phytosterols

scientific article published on 01 January 2019

Molecular analysis of chylomicronemia in a clinical laboratory setting: diagnosis of 13 cases of lipoprotein lipase deficiency.

scientific article published in December 2013

Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice

scientific article published on 21 November 2020

PPAR-β/δ activation promotes phospholipid transfer protein expression.

scientific article

Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment

scientific article published on 23 December 2020

Phenol-Enriched Virgin Olive Oil Promotes Macrophage-Specific Reverse Cholesterol Transport In Vivo

scientific article published on 03 August 2020

Phenytoin treatment reduces atherosclerosis in mice through mechanisms independent of plasma HDL-cholesterol concentration.

scientific article

Phytosterols and Health: Current Status and Future Perspectives

scientific article published on 01 January 2019

Phytosterols inhibit the tumor growth and lipoprotein oxidizability induced by a high-fat diet in mice with inherited breast cancer.

scientific article published on 30 May 2012

Pitfalls of direct HDL-cholesterol measurements in mouse models of hyperlipidemia and atherosclerosis

scientific article published on 01 September 1999

Quantification of In Vitro Macrophage Cholesterol Efflux and In Vivo Macrophage-Specific Reverse Cholesterol Transport.

scientific article published on January 2015

Resveratrol administration or SIRT1 overexpression does not increase LXR signaling and macrophage-to-feces reverse cholesterol transport in vivo.

scientific article

Role of apoA-II in lipid metabolism and atherosclerosis: advances in the study of an enigmatic protein ⬇️

scientific article (publication date: November 2001)

Seeking Novel Targets for Improving In Vivo Macrophage-Specific Reverse Cholesterol Transport: Translating Basic Science into New Therapies for the Prevention and Treatment of Atherosclerosis

scientific article published on 01 March 2011

Serum microRNA-1 and microRNA-133a levels reflect myocardial steatosis in uncomplicated type 2 diabetes

scientific article

Subcutaneous Administration of Apolipoprotein J-Derived Mimetic Peptide d-[113-122]apoJ Improves LDL and HDL Function and Prevents Atherosclerosis in LDLR-KO Mice

scientific article published on 29 May 2020

The Cholesterol Content of Western Diets Plays a Major Role in the Paradoxical Increase in High-Density Lipoprotein Cholesterol and Upregulates the Macrophage Reverse Cholesterol Transport Pathway

scientific article published on 01 November 2011

The results in rodent models of atherosclerosis are not interchangeable

scientific article published on 24 July 2007

The role of the gut in reverse cholesterol transport – Focus on the enterocyte ⬇️

scientific article published on April 20, 2013

Trimethylamine -Oxide: A Link among Diet, Gut Microbiota, Gene Regulation of Liver and Intestine Cholesterol Homeostasis and HDL Function

article

VLDL and apolipoprotein CIII induce ER stress and inflammation and attenuate insulin signalling via Toll-like receptor 2 in mouse skeletal muscle cells.

scientific article published on 23 August 2017

List of works by Joan Carles Escola-Gil

A Functional Virgin Olive Oil Enriched with Olive Oil and Thyme Phenolic Compounds Improves the Expression of Cholesterol Efflux-Related Genes: A Randomized, Crossover, Controlled Trial

APOA1 oxidation is associated to dysfunctional high-density lipoproteins in human abdominal aortic aneurysm.

ATP-binding cassette G5/G8 deficiency causes hypertriglyceridemia by affecting multiple metabolic pathways.

Acute Psychological Stress Accelerates Reverse Cholesterol Transport via Corticosterone-Dependent Inhibition of Intestinal Cholesterol Absorption ⬇️

Administration of CORM-2 inhibits diabetic neuropathy but does not reduce dyslipidemia in diabetic mice

Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy

Antiatherogenic role of high-density lipoproteins: insights from genetically engineered-mice

ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer.

Apolipoprotein Mimetics in Cancer

Are LXR-regulated genes a major molecular target of plant sterols/stanols?

CETP activity variation in mice does not affect two major HDL antiatherogenic properties: macrophage-specific reverse cholesterol transport and LDL antioxidant protection

Cholesterol and 27-hydroxycholesterol promote thyroid carcinoma aggressiveness

Cholesterol efflux and reverse cholesterol transport

Chronic intermittent psychological stress promotes macrophage reverse cholesterol transport by impairing bile acid absorption in mice

Chylomicrons: Advances in biology, pathology, laboratory testing, and therapeutics.

Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport

Cross-Talk between Inflammatory Mediators and the Epithelial Mesenchymal Transition Process in the Development of Thyroid Carcinoma.

Dietary phytosterols modulate T-helper immune response but do not induce apparent anti-inflammatory effects in a mouse model of acute, aseptic inflammation

Differential effects of gemfibrozil and fenofibrate on reverse cholesterol transport from macrophages to feces in vivo.

Effects of Virgin Olive Oil and Phenol-Enriched Virgin Olive Oils on Lipoprotein Atherogenicity

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice.

Expression of human apolipoprotein A-II in apolipoprotein E-deficient mice induces features of familial combined hyperlipidemia

Free cholesterol deposition in the cornea of human apolipoprotein A-II transgenic mice with functional lecithin: cholesterol acyltransferase deficiency

Gene Variant and Level of IL-1β in Ischemic Stroke Patients With and Without Type 2 Diabetes Mellitus

HDL and LDL: Potential New Players in Breast Cancer Development

HDL and lifestyle interventions

Hepatic lipase- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT and HDL antioxidant properties.

Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease.

Human ApoA-I Overexpression Enhances Macrophage-Specific Reverse Cholesterol Transport but Fails to Prevent Inherited Diabesity in Mice ⬇️

Human apolipoprotein A-II determines plasma triglycerides by regulating lipoprotein lipase activity and high-density lipoprotein proteome.

Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential.

Human apolipoprotein A-II is a pro-atherogenic molecule when it is expressed in transgenic mice at a level similar to that in humans: evidence of a potentially relevant species-specific interaction with diet

Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake

Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake.

Identification and validation of common molecular targets of hydroxytyrosol

IgG Anti-High Density Lipoprotein Antibodies Are Elevated in Abdominal Aortic Aneurysm and Associated with Lipid Profile and Clinical Features

Impaired HDL (High-Density Lipoprotein)-Mediated Macrophage Cholesterol Efflux in Patients With Abdominal Aortic Aneurysm-Brief Report

LXR-dependent regulation of macrophage-specific reverse cholesterol transport is impaired in a model of genetic diabesity.

Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: "Herniated" HDL, a common feature in diabetes

Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.

Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity

Low-density lipoproteins from embryonic cerebrospinal fluid are required for neural differentiation

Macrophage Cholesterol Efflux Downregulation Is Not Associated with Abdominal Aortic Aneurysm (AAA) Progression

Manipulation of inflammation modulates hyperlipidemia in apolipoprotein E-deficient mice: A possible role for interleukin-6

Mast cell activation in vivo impairs the macrophage reverse cholesterol transport pathway in the mouse

Methionine-induced hyperhomocysteinemia impairs the antioxidant ability of high-density lipoproteins without reducing in vivo macrophage-specific reverse cholesterol transport.

Modulation of autoimmune arthritis severity in mice by apolipoprotein E (ApoE) and cholesterol.

Molecular Insights into the Mechanisms Underlying the Cholesterol- Lowering Effects of Phytosterols

Molecular analysis of chylomicronemia in a clinical laboratory setting: diagnosis of 13 cases of lipoprotein lipase deficiency.

Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice

PPAR-β/δ activation promotes phospholipid transfer protein expression.

Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment

Phenol-Enriched Virgin Olive Oil Promotes Macrophage-Specific Reverse Cholesterol Transport In Vivo

Phenytoin treatment reduces atherosclerosis in mice through mechanisms independent of plasma HDL-cholesterol concentration.

Phytosterols and Health: Current Status and Future Perspectives

Phytosterols inhibit the tumor growth and lipoprotein oxidizability induced by a high-fat diet in mice with inherited breast cancer.

Pitfalls of direct HDL-cholesterol measurements in mouse models of hyperlipidemia and atherosclerosis

Quantification of In Vitro Macrophage Cholesterol Efflux and In Vivo Macrophage-Specific Reverse Cholesterol Transport.

Resveratrol administration or SIRT1 overexpression does not increase LXR signaling and macrophage-to-feces reverse cholesterol transport in vivo.

Role of apoA-II in lipid metabolism and atherosclerosis: advances in the study of an enigmatic protein ⬇️

Seeking Novel Targets for Improving In Vivo Macrophage-Specific Reverse Cholesterol Transport: Translating Basic Science into New Therapies for the Prevention and Treatment of Atherosclerosis

Serum microRNA-1 and microRNA-133a levels reflect myocardial steatosis in uncomplicated type 2 diabetes

Subcutaneous Administration of Apolipoprotein J-Derived Mimetic Peptide d-[113-122]apoJ Improves LDL and HDL Function and Prevents Atherosclerosis in LDLR-KO Mice

The Cholesterol Content of Western Diets Plays a Major Role in the Paradoxical Increase in High-Density Lipoprotein Cholesterol and Upregulates the Macrophage Reverse Cholesterol Transport Pathway

The results in rodent models of atherosclerosis are not interchangeable

The role of the gut in reverse cholesterol transport – Focus on the enterocyte ⬇️

Trimethylamine -Oxide: A Link among Diet, Gut Microbiota, Gene Regulation of Liver and Intestine Cholesterol Homeostasis and HDL Function

VLDL and apolipoprotein CIII induce ER stress and inflammation and attenuate insulin signalling via Toll-like receptor 2 in mouse skeletal muscle cells.