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List of works by Jose Angel Ruiz-Ortega

Buspirone anti-dyskinetic effect is correlated with temporal normalization of dysregulated striatal DRD1 signalling in L-DOPA-treated rats

scientific article published on 10 December 2013

Buspirone requires the intact nigrostriatal pathway to reduce the activity of the subthalamic nucleus via 5-HT1A receptors.

scientific article published on 11 December 2015

Chronic L-DOPA administration increases the firing rate but does not reverse enhanced slow frequency oscillatory activity and synchronization in substantia nigra pars reticulata neurons from 6-hydroxydopamine-lesioned rats

scientific article published on 4 February 2016

Deleterious Effects of VEGFR2 and RET Inhibition in a Preclinical Model of Parkinson's Disease

scientific article published on 24 August 2017

Endocannabinoid modulation of dopaminergic motor circuits.

scientific article published on 12 June 2012

Excitatory regulation of noradrenergic neurons by L-arginine/nitric oxide pathway in the rat locus coeruleus in vivo.

scientific article

Imidazoline-induced inhibition of firing rate of 5-HT neurons in rat dorsal raphe by modulation of extracellular 5-HT levels.

scientific article

In vivo administration of VEGF- and GDNF-releasing biodegradable polymeric microspheres in a severe lesion model of Parkinson's disease.

scientific article published on 30 April 2013

Increased antiparkinson efficacy of the combined administration of VEGF- and GDNF-loaded nanospheres in a partial lesion model of Parkinson's disease.

scientific article

Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo

scientific article published in October 2000

Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease.

scientific article published on 17 March 2014

Levodopa-induced dyskinesias in Parkinson disease are independent of the extent of striatal dopaminergic denervation: a pharmacological and SPECT study.

scientific article published in November 2009

Modulation of the subthalamic nucleus activity by serotonergic agents and fluoxetine administration.

scientific article

Morphological Changes in a Severe Model of Parkinson's Disease and Its Suitability to Test the Therapeutic Effects of Microencapsulated Neurotrophic Factors.

scientific article published on 14 November 2016

Nanodelivery of Cerebrolysin and Rearing in Enriched Environment Induce Neuroprotective Effects in a Preclinical Rat Model of Parkinson's Disease.

scientific article

Nigrostriatal denervation changes the effect of cannabinoids on subthalamic neuronal activity in rats.

scientific article published on 20 October 2010

Pharmacological treatment of Parkinson's disease: life beyond dopamine D2/D3 receptors?

scientific article published on 04 February 2008

Preclinical pharmacology of F-98214-TA, a novel potent serotonin and norepinephrine uptake inhibitor with antidepressant and anxiolytic properties.

scientific article published on 19 October 2005

Stimulatory effect of harmane and other beta-carbolines on locus coeruleus neurons in anaesthetized rats.

scientific article published in August 2001

The role of the subthalamic nucleus in L-DOPA induced dyskinesia in 6-hydroxydopamine lesioned rats

scientific article

The stimulatory effect of clonidine on locus coeruleus neurons of rats with inactivated α2-adrenoceptors: involvement of imidazoline receptors located in the nucleus paragigantocellularis

scientific article published on 27 January 1997

The stimulatory effect of clonidine through imidazoline receptors on locus coeruleus noradrenergic neurones is mediated by excitatory amino acids and modulated by serotonin

scientific article published on 01 August 1995

Topographical Distribution of Morphological Changes in a Partial Model of Parkinson's Disease--Effects of Nanoencapsulated Neurotrophic Factors Administration.

scientific article published on 4 June 2015

Two opposite effects of Delta(9)-tetrahydrocannabinol on subthalamic nucleus neuron activity: involvement of GABAergic and glutamatergic neurotransmission

scientific journal article

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