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List of works by Myles Lewis

Activation of naïve CD4+ T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4+ T cells

scientific article published on 19 March 2019

Adhesion molecules, mycophenolate mofetil and systemic lupus erythematosus.

scientific article

Anti-TNF-alpha agents and endothelial function in rheumatoid arthritis: a systematic review and meta-analysis

scientific article

Autoantibodies targeting TLR and SMAD pathways define new subgroups in systemic lupus erythematosus.

scientific article published on 22 March 2018

B Cell Synovitis and Clinical Phenotypes in Rheumatoid Arthritis: Relationship to Disease Stages and Drug Exposure

scientific article published on 29 November 2019

Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis

scientific article published on 27 October 2020

Brainstem Infarction during Long-Haul Air Travel

scientific article published on 02 November 2004

De novo mutations implicate novel genes in Systemic Lupus Erythematosus.

scientific article published on 21 November 2017

Distinct roles for complement in glomerulonephritis and atherosclerosis revealed in mice with a combination of lupus and hyperlipidemia.

scientific article published on August 2012

Distinct synovial tissue macrophage subsets regulate inflammation and remission in rheumatoid arthritis

scientific article published on 29 June 2020

Economy class stroke syndromes: vertebral artery dissection revisited.

scientific article published in November 2003

Ectopic lymphoid neogenesis in rheumatic autoimmune diseases

scientific article

Effect of UBE2L3 genotype on regulation of the linear ubiquitin chain assembly complex in systemic lupus erythematosus.

scientific article published on February 2015

Extracellular traps and PAD4 released by macrophages induce citrullination and auto-antibody production in autoimmune arthritis

scientific article published on 02 July 2019

IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors

scientific article published on 26 November 2020

Immunoglobulin M is required for protection against atherosclerosis in low-density lipoprotein receptor-deficient mice

scientific article published on 20 July 2009

Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis

scientific article published on 01 April 2020

Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response

scientific article published on 30 July 2020

Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring

scientific article published on 07 November 2019

M3C: Monte Carlo reference-based consensus clustering

scientific article published on 04 February 2020

Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes

scientific article published on 01 August 2019

NKp30 Receptor Upregulation in Salivary Glands of Sjögren's Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment

scientific article published on 14 September 2021

New Insights into the Role of Tyro3, Axl, and Mer Receptors in Rheumatoid Arthritis

scientific article published on 19 January 2020

PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes

scientific article published on 26 February 2019

RNA sequencing and machine learning as molecular scalpels

scientific article published on 01 July 2018

Response to 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Humby et al

scientific article published on 13 July 2019

Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial

scientific article published on 19 May 2022

Spectrum: fast density-aware spectral clustering for single and multi-omic data

scientific article published on 01 February 2020

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

scientific article published on 16 March 2019

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohor

scientific article published on 02 October 2019

Systemic lupus erythematous with recurrent Guillain-Barré-like syndrome treated with intravenous immunoglobulins.

scientific article published in January 2003

The Autoimmune Susceptibility Gene C5orf30 Regulates Macrophage-Mediated Resolution of Inflammation

scientific article published on 18 January 2019

The effect of ethnicity and genetic ancestry on the epidemiology, clinical features and outcome of systemic lupus erythematosus.

scientific article published on 10 December 2016

UBE2L3 polymorphism amplifies NF-κB activation and promotes plasma cell development, linking linear ubiquitination to multiple autoimmune diseases.

scientific article

Validity of a two-component imaging-derived disease activity score for improved assessment of synovitis in early rheumatoid arthritis

scientific article published on 01 March 2019

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