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List of works by Lei Jin

A p53-responsive microRNA network promotes cancer cell quiescence

scientific article published on 09 October 2018

ACTN4 regulates the stability of RIPK1 in melanoma.

scientific article

AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma

scientific article (publication date: 7 November 2013)

Adipocytes contribute to resistance of human melanoma cells to chemotherapy and targeted therapy.

scientific article published on April 2014

BAG3-dependent expression of Mcl-1 confers resistance of mutant KRAS colon cancer cells to the HSP90 inhibitor AUY922.

scientific article

BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma

scientific article published on 9 May 2017

Cooperativity of HOXA5 and STAT3 is critical for HDAC8 inhibition-mediated transcriptional activation of PD-L1 in human melanoma cells.

scientific article published on 22 November 2017

Cotargeting histone deacetylases and oncogenic BRAF synergistically kills human melanoma cells by necrosis independently of RIPK1 and RIPK3.

scientific article published on 06 June 2013

Dual functions for OVAAL in initiation of RAF/MEK/ERK prosurvival signals and evasion of p27-mediated cellular senescence

article published in the Proceedings of the National Academy of Sciences of the United States of America

E2F1 represses beta-catenin/TCF activity by direct up-regulation of Siah1.

scientific article published on August 2009

Endoplasmic reticulum stress inhibits cell cycle progression via induction of p27 in melanoma cells.

scientific article

GUARDIN is a p53-responsive long non-coding RNA that is essential for genomic stability.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors.

scientific article published on January 2012

INPP4B is an oncogenic regulator in human colon cancer.

scientific article published on 28 September 2015

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas.

scientific article published on 9 November 2015

Inhibition of HSP90 by AUY922 Preferentially Kills Mutant KRAS Colon Cancer Cells by Activating Bim through ER Stress.

scientific article published on February 2016

Involvement of vacuolar H(+)-ATPase in killing of human melanoma cells by the sphingosine kinase analogue FTY720.

scientific article

LncRNA IDH1-AS1 links the functions of c-Myc and HIF1α via IDH1 to regulate the Warburg effect.

scientific article

Loss of PI(4,5)P2 5-Phosphatase A Contributes to Resistance of Human Melanoma Cells to RAF/MEK Inhibitors.

scientific article published on August 2013

MicroRNA-149*, a p53-responsive microRNA, functions as an oncogenic regulator in human melanoma

scientific article

MicroRNA-497 targets insulin-like growth factor 1 receptor and has a tumour suppressive role in human colorectal cancer

scientific article

MicroRNA-645 is an oncogenic regulator in colon cancer.

scientific article published on 15 May 2017

Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress.

scientific article published on 6 August 2013

Oncogenic suppression of PHLPP1 in human melanoma

scientific article published on 14 October 2013

Phenotypic characterization and risk factors for microtia in East China, a case-control study.

scientific article published on 11 September 2014

RIP1 Kinase Is an Oncogenic Driver in Melanoma.

scientific article

RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors.

scientific article

RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy.

scientific article

Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922

scientific article published on 6 July 2016

Reactive Oxygen Species Dictate the Apoptotic Response of Melanoma Cells to TH588.

scientific article published on 14 July 2016

Recognition of unmodified histone H3 by the first PHD finger of bromodomain-PHD finger protein 2 provides insights into the regulation of histone acetyltransferases monocytic leukemic zinc-finger protein (MOZ) and MOZ-related factor (MORF)

scientific article

Regulation of PD-L1: a novel role of pro-survival signalling in cancer.

scientific article published on 17 December 2015

Skp2-Mediated Stabilization of MTH1 Promotes Survival of Melanoma Cells upon Oxidative Stress.

scientific article

Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress ⬇️

scientific article published on June 28, 2012

Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress

scientific article published on 12 November 2013

Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis

scientific article published on 26 October 2020

The double life of RIPK1.

scientific article published on 26 May 2015

The epigenetic regulator I-BET151 induces BIM-dependent apoptosis and cell cycle arrest of human melanoma cells.

scientific article

The melanoma-associated antigen MAGE-D2 suppresses TRAIL receptor 2 and protects against TRAIL-induced apoptosis in human melanoma cells.

scientific article

c-Myc inactivation of p53 through the pan-cancer lncRNA MILIP drives cancer pathogenesis

scientific article published on 05 October 2020

p53-facilitated miR-199a-3p regulates somatic cell reprogramming.

scientific article published on July 2012

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