List of works - Jin-Soo Kim

A homozygous Keap1-knockout human embryonic stem cell line generated using CRISPR/Cas9 mediates gene targeting

scientific article

A library of TAL effector nucleases spanning the human genome ⬇️

scientific article published on February 17, 2013

A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system

scientific article published on 4 March 2016

Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy

scientific article published on 27 April 2018

Adenine base editors catalyze cytosine conversions in human cells

scientific article published on 23 September 2019

Analysis of Targeted Chromosomal Deletions Induced by Zinc Finger Nucleases ⬇️

scientific article published on August 1, 2010

Apancreatic pigs cloned using Pdx1-disrupted fibroblasts created via TALEN-mediated mutagenesis

scientific article published on 14 December 2017

Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection

scientific article

Author Correction: Precision genome engineering through adenine base editing in plants

article

Bypassing GMO regulations with CRISPR gene editing

scientific article published in October 2016

CRISPR RNAs trigger innate immune responses in human cells

scientific article published on 22 February 2018

CRISPR germline engineering--the community speaks

scientific article published on May 2015

CRISPR-Cas9 Screening of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells

scientific article published in 2019

CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration.

scientific article

CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion

scientific article published on 20 December 2018

CRISPR/Cpf1-mediated DNA-free plant genome editing

scientific article published on 16 February 2017

Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9.

scientific article

Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites

scientific article published on 10 September 2015

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

scientific article

Cas-analyzer: an online tool for assessing genome editing results using NGS data

scientific article

Correction of a pathogenic gene mutation in human embryos

scientific article published on 2 August 2017

Corrigendum: Genotyping with CRISPR-Cas-derived RNA-guided endonucleases

scientific article published on 6 February 2015

DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA

DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins

scientific article

DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins

scientific article (publication date: 2016)

Dibromobimane as a Fluorescent Crosslinking Reagent

scientific article published on 01 February 1995

Digenome-seq web tool for profiling CRISPR specificity

scientific article

Direct observation of DNA target searching and cleavage by CRISPR-Cas12a

scientific article published in Nature Communications

Directed evolution of CRISPR-Cas9 to increase its specificity

scientific article published in Nature Communications

Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells

scientific article

Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells

scientific article published on 22 October 2015

Efficient genome editing in hematopoietic stem cells with helper-dependent Ad5/35 vectors expressing site-specific endonucleases under microRNA regulation

scientific article published on 14 January 2015

Engineering of GAL1 promoter-driven expression system with artificial transcription factors.

scientific article published on 17 October 2006

Enrichment of cells with TALEN-induced mutations using surrogate reporters

scientific article

Erratum: Genome-wide target specificities of CRISPR RNA-guided programmable deaminases

scientific article published in August 2017

Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute

scientific article published on 28 November 2016

Fine-Tuning Next-Generation Genome Editing Tools.

scientific article published on 7 May 2016

Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9

scholarly article by Taeyoung Koo published in June 2018

Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1.

scientific article published on 23 November 2017

Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus

scientific article published on 30 December 2014

Generation of a Nrf2 homozygous knockout human embryonic stem cell line using CRISPR/Cas9.

scientific article

Genome editing comes of age.

scientific article

Genome engineering in human cells

scientific article

Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration

scientific article

Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells

scientific article

Genome-wide specificity of dCpf1 cytidine base editors

scientific article published on 13 August 2020

Genome-wide target specificities of CRISPR RNA-guided programmable deaminases

scientific article published on 10 April 2017

Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

scientific article published on 19 January 2016

Genome-wide target specificity of CRISPR RNA-guided adenine base editors

scientific article published on 04 March 2019

Genotyping with CRISPR-Cas-derived RNA-guided endonucleases

scientific article published on January 2014

Getting a handhold on DNA: design of poly-zinc finger proteins with femtomolar dissociation constants.

scientific article

Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins

scientific article published on 26 August 2013

Highly efficient RNA-guided base editing in mouse embryos

scientific article published on 27 February 2017

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

scientific article

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

scientific article

Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target

scientific article published on 07 March 2019

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering

scientific article published on 13 December 2017

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

scientific article

Long Terminal Repeat CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects

scientific article published on 6 March 2018

Long-Term Effects of In Vivo Genome Editing in the Mouse Retina Using Campylobacter jejuni Cas9 Expressed via Adeno-Associated Virus

scientific article published on 17 October 2018

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

scientific article

Microhomology-based choice of Cas9 nuclease target sites

scientific article published in July 2014

Myofibroblast in the ligamentum flavum hypertrophic activity

scientific article published on 8 February 2017

Novel cancer antiangiotherapy using the VEGF promoter-targeted artificial zinc-finger protein and oncolytic adenovirus.

scientific article

Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases

scientific article published on 18 January 2022

Precision genome engineering through adenine and cytosine base editing.

scientific article published on 26 February 2018

Precision genome engineering through adenine base editing in plants

article

Precision genome engineering with programmable DNA-nicking enzymes

scientific article

Production of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment System

scientific article

Publisher Correction: Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1.

scientific article published on 16 January 2018

Questioning unexpected CRISPR off-target mutations in vivo

article published in 2017

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo"

Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo”

SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells

scientific article published on 30 September 2016

Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression

scientific article published on 31 May 2017

Site-directed mutagenesis in Petunia × hybrida protoplast system using direct delivery of purified recombinant Cas9 ribonucleoproteins

scientific article published on 29 January 2016

Site-specific DNA excision via engineered zinc finger nucleases.

scientific article

Sometimes you're the scooper, and sometimes you get scooped: How to turn both into something good

scientific article published on 16 July 2018

Structural insights into the apo-structure of Cpf1 protein from Francisella novicida.

scientific article published on 8 March 2018

Structural roles of guide RNAs in the nuclease activity of Cas9 endonuclease

scientific article

Suppression of vascular endothelial growth factor expression at the transcriptional and post-transcriptional levels

scientific article

Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations

scientific article

TALEN-based knockout library for human microRNAs

scientific article

TALENs and ZFNs are associated with different mutation signatures ⬇️

scientific article published on February 10, 2013

Targeted Genome Editing for Crop Improvement

Targeted chromosomal deletions in human cells using zinc finger nucleases

scientific article

Targeted chromosomal duplications and inversions in the human genome using zinc finger nucleases

scientific article published on 19 December 2011

Targeted knockout of a chemokine-like gene increases anxiety and fear responses

scientific article published on 16 January 2018

Targeted mutagenesis in mice by electroporation of Cpf1 ribonucleoproteins

scientific article

The efficacy of CRISPR-mediated cytosine base editing with the RPS5a promoter in Arabidopsis thaliana

scientific article published on 13 April 2021

The road ahead in genetics and genomics

scientific article published on 24 August 2020

Therapeutic applications of CRISPR RNA-guided genome editing

scientific article

Towards therapeutic base editing

scientific article published on 01 October 2018

Transduction of artificial transcriptional regulatory proteins into human cells

scientific article published on 21 July 2008

Transient expression of an adenine base editor corrects the Hutchinson-Gilford progeria syndrome mutation and improves the skin phenotype in mice

scientific article published on 02 June 2022

Unexpected CRISPR on-target effects

scientific article published on 30 July 2018

Voices of biotech

scientific article published on March 2016

Web-based design and analysis tools for CRISPR base editing

article by Gue-Ho Hwang et al published 27 December 2018 in BMC Bioinformatics

Zinc finger proteins as designer transcription factors.

scientific article published in March 2000

List of works by Jin-Soo Kim

A homozygous Keap1-knockout human embryonic stem cell line generated using CRISPR/Cas9 mediates gene targeting

A library of TAL effector nucleases spanning the human genome ⬇️

A simple, flexible and high-throughput cloning system for plant genome editing via CRISPR-Cas system

Adenine base editing in mouse embryos and an adult mouse model of Duchenne muscular dystrophy

Adenine base editors catalyze cytosine conversions in human cells

Analysis of Targeted Chromosomal Deletions Induced by Zinc Finger Nucleases ⬇️

Apancreatic pigs cloned using Pdx1-disrupted fibroblasts created via TALEN-mediated mutagenesis

Arrayed CRISPR screen with image-based assay reliably uncovers host genes required for coxsackievirus infection

Author Correction: Precision genome engineering through adenine base editing in plants

Bypassing GMO regulations with CRISPR gene editing

CRISPR RNAs trigger innate immune responses in human cells

CRISPR germline engineering--the community speaks

CRISPR-Cas9 Screening of Kaposi's Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells

CRISPR-LbCpf1 prevents choroidal neovascularization in a mouse model of age-related macular degeneration.

CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion

CRISPR/Cpf1-mediated DNA-free plant genome editing

Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9.

Cas-Designer: a web-based tool for choice of CRISPR-Cas9 target sites

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Cas-analyzer: an online tool for assessing genome editing results using NGS data

Correction of a pathogenic gene mutation in human embryos

Corrigendum: Genotyping with CRISPR-Cas-derived RNA-guided endonucleases

DIG-seq: a genome-wide CRISPR off-target profiling method using chromatin DNA

DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins

DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins

Dibromobimane as a Fluorescent Crosslinking Reagent

Digenome-seq web tool for profiling CRISPR specificity

Direct observation of DNA target searching and cleavage by CRISPR-Cas12a

Directed evolution of CRISPR-Cas9 to increase its specificity

Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells

Efficient delivery of nuclease proteins for genome editing in human stem cells and primary cells

Efficient genome editing in hematopoietic stem cells with helper-dependent Ad5/35 vectors expressing site-specific endonucleases under microRNA regulation

Engineering of GAL1 promoter-driven expression system with artificial transcription factors.

Enrichment of cells with TALEN-induced mutations using surrogate reporters

Erratum: Genome-wide target specificities of CRISPR RNA-guided programmable deaminases

Failure to detect DNA-guided genome editing using Natronobacterium gregoryi Argonaute

Fine-Tuning Next-Generation Genome Editing Tools.

Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9

Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1.

Gene inactivation using the CRISPR/Cas9 system in the nematode Pristionchus pacificus

Generation of a Nrf2 homozygous knockout human embryonic stem cell line using CRISPR/Cas9.

Genome editing comes of age.

Genome engineering in human cells

Genome surgery using Cas9 ribonucleoproteins for the treatment of age-related macular degeneration

Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells

Genome-wide specificity of dCpf1 cytidine base editors

Genome-wide target specificities of CRISPR RNA-guided programmable deaminases

Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq

Genome-wide target specificity of CRISPR RNA-guided adenine base editors

Genotyping with CRISPR-Cas-derived RNA-guided endonucleases

Getting a handhold on DNA: design of poly-zinc finger proteins with femtomolar dissociation constants.

Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins

Highly efficient RNA-guided base editing in mouse embryos

Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins

Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases

Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target

In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering

In vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni

Long Terminal Repeat CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects

Long-Term Effects of In Vivo Genome Editing in the Mouse Retina Using Campylobacter jejuni Cas9 Expressed via Adeno-Associated Virus

Measuring and Reducing Off-Target Activities of Programmable Nucleases Including CRISPR-Cas9

Microhomology-based choice of Cas9 nuclease target sites

Myofibroblast in the ligamentum flavum hypertrophic activity

Novel cancer antiangiotherapy using the VEGF promoter-targeted artificial zinc-finger protein and oncolytic adenovirus.

Nuclear and mitochondrial DNA editing in human cells with zinc finger deaminases

Precision genome engineering through adenine and cytosine base editing.

Precision genome engineering through adenine base editing in plants

Precision genome engineering with programmable DNA-nicking enzymes

Production of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment System

Publisher Correction: Fusion guide RNAs for orthogonal gene manipulation with Cas9 and Cpf1.

Questioning unexpected CRISPR off-target mutations in vivo

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo"

Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo”

SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells

Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression

Site-directed mutagenesis in Petunia × hybrida protoplast system using direct delivery of purified recombinant Cas9 ribonucleoproteins

Site-specific DNA excision via engineered zinc finger nucleases.

Sometimes you're the scooper, and sometimes you get scooped: How to turn both into something good

Structural insights into the apo-structure of Cpf1 protein from Francisella novicida.