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List of works by Nicolas Aznar

A Daple-Akt feed-forward loop enhances noncanonical Wnt signals by compartmentalizing β-catenin.

scientific article published on 11 October 2017

AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin

scientific article

Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.

scientific article

Biochemical, Biophysical and Cellular Techniques to Study the Guanine Nucleotide Exchange Factor, GIV/Girdin.

scientific article published on 7 December 2016

Convergence of Wnt, growth factor, and heterotrimeric G protein signals on the guanine nucleotide exchange factor Daple.

scientific article published on 27 February 2018

Cyclin-dependent kinase 5 activates guanine nucleotide exchange factor GIV/Girdin to orchestrate migration-proliferation dichotomy

scientific article

Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling

scientific article published on 30 June 2015

Heterotrimeric G protein signaling via GIV/Girdin: Breaking the rules of engagement, space, and time.

scientific article published on 16 February 2016

Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity.

scientific article published on 24 July 2018

LKB1 signaling in cephalic neural crest cells is essential for vertebrate head development

scientific article published on 12 August 2016

Mitochondrial BMI1 maintains bioenergetic homeostasis in cells

scientific article published on 9 September 2016

Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.

scientific article published on 22 August 2011

Primary Cilia Bend LKB1 and mTOR to Their Will ⬇️

scientific article published on December 14, 2010

Prognostic Relevance of CCDC88C (Daple) Transcripts in the Peripheral Blood of Patients with Cutaneous Melanoma

scientific article published in Scientific Reports

Prognostic impact of total and tyrosine phosphorylated GIV/Girdin in breast cancers

scientific article published on 20 July 2016

Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin

scientific article published on 18 March 2013

Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi

scientific article published on 02 November 2020

Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin

scientific article

Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors.

scientific article published on 29 April 2015

Two Isoforms of the Guanine Nucleotide Exchange Factor, Daple/CCDC88C Cooperate as Tumor Suppressors

scientific article published on 20 August 2019

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