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List of works by John Mascarenhas

1090. Practicing Antimicrobial Stewardship: De-escalating Empiric Antibiotics in Patients with Acute Myelogenous Leukemia and Neutropenic Fever

A Case Report of Chronic Myelogenous Leukemia in a Patient With Multiple Myeloma and a Review of the Literature ⬇️

scientific article published on November 15, 2012

A comprehensive review and analysis of the effect of ruxolitinib therapy on the survival of patients with myelofibrosis ⬇️

scientific article published on 09 April 2013

A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF).

scientific article

A phase I study of panobinostat and ruxolitinib in patients with primary myelofibrosis (PMF) and post--polycythemia vera/essential thrombocythemia myelofibrosis (post--PV/ET MF)

scientific article published on 16 November 2019

A phase I, open-label, multi-center study of the JAK2 inhibitor AZD1480 in patients with myelofibrosis

scientific article

A prospective evaluation of pegylated interferon alfa-2a therapy in patients with polycythemia vera and essential thrombocythemia with a prior splanchnic vein thrombosis

scientific article published on 30 July 2019

A thrombopoietin receptor antagonist is capable of depleting myelofibrosis hematopoietic stem and progenitor cells

scientific article published on 25 April 2016

Admission D-dimer levels, D-dimer trends, and outcomes in COVID-19

scientific article published on 20 August 2020

Advanced forms of MPNs are accompanied by chromosomal abnormalities that lead to dysregulation of TP53

scientific article published on 01 December 2018

Advances in myelofibrosis: a clinical case approach

scientific article published on October 2013

An Opportunity for Hospice Referral in Acute Myeloid Leukemia: Prognostic Significance of Hospitalization Status at Time of Second Cycle of Hypomethylating Agents for Patients Ineligible for Intensive Induction Chemotherapy

scientific article published on 01 November 2020

Anagrelide hydrochloride and ruxolitinib for treatment of polycythemia vera

scientific article published on 14 April 2015

Associations of Physical and Psychologic Symptom Burden in Patients With Philadelphia Chromosome-Negative Myeloproliferative Neoplasms ⬇️

scientific article published on 31 January 2018

Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies

scientific article

Characteristics, anticoagulation, and outcomes of portal vein thrombosis after intra-abdominal surgery

scientific article published on 24 December 2020

Clarifying the use of ruxolitinib in patients with myelofibrosis

scientific article published on July 2013

Clinical Benefit Derived from Decitabine Therapy for Advanced Phases of Myeloproliferative Neoplasms

scientific article published on 11 March 2020

Clinical developments in epigenetic-directed therapies in acute myeloid leukemia

scientific article published on 01 March 2020

Coexistence of myeloproliferative neoplasm and plasma-cell dyscrasia.

scientific article published on 30 September 2013

Combination treatment in vitro with Nutlin, a small-molecule antagonist of MDM2, and pegylated interferon-α 2a specifically targets JAK2V617F-positive polycythemia vera cells

scientific article

Comment on "Next-generation sequencing in the diagnosis of non-cirrhotic splanchnic vein thrombosis"

scientific article published on 24 September 2020

Comparing the epidemiology, clinical characteristics and prognostic factors of acute myeloid leukemia with and without acute promyelocytic leukemia

scientific article published on 01 July 2019

Continued Role of Splenectomy in the Management of Patients With Myelofibrosis

scientific article published on 08 June 2016

Current and evolving understanding of atypical chronic myeloid leukemia

scientific article published on 29 July 2018

Determining the recommended dose of pacritinib: results from the PAC203 dose-finding trial in advanced myelofibrosis

scientific article published on 01 November 2020

Development of extramedullary sites of leukaemia during ruxolitinib therapy for myelofibrosis

scientific article

Development of t(8;21) and RUNX1-RUNX1T1 in the Philadelphia-positive clone of a patient with chronic myelogenous leukemia: additional evidence for multiple steps involved in disease progression

scientific article published on March 2011

Differences in the clinical and genetic profile of Hispanic and non-Hispanic acute myeloid leukemia patients

scientific article published on 19 December 2018

Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologists/oncologists in the United States: Findings from the MPN Landmark survey

scientific article published on 30 September 2016

Discontinuing Tyrosine Kinase Inhibitor Therapy in Chronic Myelogenous Leukemia: Current Understanding and Future Directions.

scientific article published on 16 June 2016

Effects of ruxolitinib treatment on metabolic and nutritional parameters in patients with myelofibrosis from COMFORT-I.

scientific article published on 27 December 2014

Eosinophilia in acute myeloid leukemia: Overlooked and underexamined

scientific article published on 30 March 2019

Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies ⬇️

scientific article published on July 9, 2011

Evolving Understanding of Chronic Myelomonocytic Leukemia: Implications for Future Treatment Paradigms

scientific article published on 23 May 2018

Experience with pegylated interferon -2a in advanced myeloproliferative neoplasms in an international cohort of 118 patients ⬇️

scientific article published on March 14, 2012

Hemichorea in a patient with JAK2V617F blood cells ⬇️

scientific article published on February 14, 2013

Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis

scientific article published on 06 January 2019

Impact of anticoagulation prior to COVID-19 infection: a propensity score-matched cohort study

scientific article published on 27 May 2020

Implications of Mutation Profiling in Myeloid Malignancies-PART 1: Myelodysplastic Syndromes and Acute Myeloid Leukemia

scientific article published on 15 April 2018

Increased differentiation of dermal mast cells in mice lacking the Mpl gene

scientific article

Interferon-alpha targets JAK2V617F-positive hematopoietic progenitor cells and acts through the p38 MAPK pathway

scientific article

Ironing out the details of iron overload in myelofibrosis: Lessons from myelodysplastic syndromes

scientific article published on 19 April 2016

Leukemic Transformation of Myeloproliferative Neoplasms: Therapeutic and Genomic Considerations

article

MDM2 inhibition: an important step forward in cancer therapy

scientific article published on 10 July 2020

MPD-RC 101 prospective study of reduced-intensity allogeneic hematopoietic stem cell transplantation in patients with myelofibrosis

scientific article

Management of cytopenias in patients with myelofibrosis treated with ruxolitinib and effect of dose modifications on efficacy outcomes

scientific article published on 17 December 2013

Metabolic Effects of JAK1/2 Inhibition in Patients with Myeloproliferative Neoplasms

scientific article published on 12 November 2019

Modern management of splenomegaly in patients with myelofibrosis

scientific article published on 17 May 2020

Myeloid/lymphoid neoplasms with FGFR1 rearrangement

scientific article

Myeloproliferative neoplasms (MPNs) have a significant impact on patients' overall health and productivity: the MPN Landmark survey

scientific article

Myeloproliferative neoplasms: new translational therapies

scientific article

Myoclonic jerks complicating treatment of acute promyelocytic leukemia: case report and literature review

scientific article published on 01 June 2019

Novel Therapies in Polycythemia Vera

scientific article published on 07 February 2020

Novel therapeutics in myeloproliferative neoplasms

scientific article published on 02 December 2020

Optimal therapy for polycythemia vera and essential thrombocythemia can only be determined by the completion of randomized clinical trials

scientific article published on June 2014

Oral idasanutlin in patients with polycythemia vera

scientific article published on 05 June 2019

Outcome of Allogeneic Hematopoietic Stem Cell Transplantation for Patients with Chronic and Advanced Phase Myelofibrosis

scientific article published on 03 September 2016

Outcomes and predictors of survival in blast phase myeloproliferative neoplasms

scientific article published on 21 May 2018

Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients with Myelofibrosis with Prior Exposure to Janus Kinase 1/2 Inhibitors.

scientific article published on 19 October 2015

Outcomes of patients with myelofibrosis treated with compassionate use pacritinib: a sponsor-independent international study.

scientific article published on 3 April 2018

Outcomes of splanchnic vein thrombosis in patients with myeloproliferative neoplasms in a single center experience

scientific article published on 16 October 2019

Pacritinib demonstrates spleen volume reduction in patients with myelofibrosis independent of JAK2V617F allele burden

scientific article published on 01 December 2020

Pacritinib vs Best Available Therapy, Including Ruxolitinib, in Patients With Myelofibrosis: A Randomized Clinical Trial

scientific article published on 8 March 2018

Panobinostat (LBH589)-induced acetylation of tubulin impairs megakaryocyte maturation and platelet formation ⬇️

scientific article published on February 27, 2012

Pathogenesis and management of acute myeloid leukemia that has evolved from a myeloproliferative neoplasm

scientific article published on March 2014

Pegylated interferon alfa-2a for polycythemia vera or essential thrombocythemia resistant or intolerant to hydroxyurea

scientific article published on 01 October 2019

Persistent leukocytosis in polycythemia vera is associated with disease evolution but not thrombosis

scientific article published on 27 February 2020

Pharmacotherapy of Myelofibrosis

scientific article

Phase 2 study of ruxolitinib and decitabine in patients with myeloproliferative neoplasm in accelerated and blast phase

scientific article published on 01 October 2020

Phase II trial of Lestaurtinib, a JAK2 inhibitor, in patients with myelofibrosis

scientific article published on 22 January 2019

Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F

scientific article (publication date: 20 November 2015)

Portal vein thrombosis patients harboring JAK2V617F have poor long-term outcomes despite anticoagulation

scientific article published on 07 February 2020

Practicing Antimicrobial Stewardship: De-Escalating Antibiotics in Patients With Acute Myeloid Leukemia and Neutropenic Fever

scientific article published on 21 April 2020

Preferences of Patients With Myeloproliferative Neoplasms for Accepting Anxiety or Depression Treatment

scientific article published on 17 August 2016

Prevalence of Cytopenia in the General Population-A National Health and Nutrition Examination Survey Analysis

scientific article published on 20 November 2020

Prevalence of Physical Problems Detected by the Distress Thermometer and Problem List in Patients With Myeloproliferative Disorders

scientific article published in December 2017

Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis

scientific article

Programmed cell death-1 pathway inhibition in myeloid malignancies: implications for myeloproliferative neoplasms

scientific article published on 6 January 2017

Psychological Manifestations of Early Childhood Adversity in the Context of Chronic Hematologic Malignancy

scientific article

Psychological Symptoms Among Patients With BCR-ABL-Negative Myeloproliferative Neoplasms

scientific article published in December 2016

Real-World Outcomes of Ruxolitinib Treatment for Polycythemia Vera

scientific article published on 29 May 2020

Reassessing the Safety Concerns of Utilizing Blood Donations from Patients with Hemochromatosis.

scientific article published on 13 September 2017

Reevaluating the role of ferritin in the diagnosis of adult secondary hemophagocytic lymphohistiocytosis

scientific article published on 11 February 2020

Refractory gout in primary myelofibrosis

scientific article published on 01 June 2019

Relevant updates in systemic mastocytosis

scientific article published on 04 April 2019

Response to meta-analysis of leukocytosis and thrombosis in essential thrombocythemia and polycythemia vera

scientific article published on 01 October 2019

Risk factors for infections and secondary malignancies in patients with a myeloproliferative neoplasm treated with ruxolitinib: a dual-center, propensity score-matched analysis

scientific article published on 12 November 2019

Role of minimal residual disease in the management of acute myeloid leukemia-a case-based discussion.

scientific article published on 27 April 2018

SLAM dunk for myelofibrosis?

scientific article published on 01 September 2019

Safety and efficacy of combined ruxolitinib and decitabine in accelerated and blast-phase myeloproliferative neoplasms

Safety, Efficacy, and Long-Term Outcomes of Anticoagulation in Cirrhotic Portal Vein Thrombosis

scientific article published on 05 November 2020

Selective Janus associated kinase 1 inhibition as a therapeutic target in myelofibrosis

scientific article

Single agent bevacizumab for myelofibrosis: results of the Myeloproliferative Disorders Research Consortium Trial

scientific article published on 28 June 2013

Single-cell analysis reveals selection of TP53-mutated clones after MDM2 inhibition

scientific article published on 01 May 2022

Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts

scientific article published on 18 June 2020

Systematic review and meta-analysis evaluating clinical outcomes in adult acute myeloid leukemia patients with central nervous system involvement

scientific article published in 2024

Systemic Mastocytosis: Clinical Update and Future Directions.

scientific article published on 05 August 2015

The Implications of Liver Biopsy Results in Patients with Myeloproliferative Neoplasms Being Treated with Ruxolitinib

article

The Natural History, Treatments, and Outcomes of Portal Vein Thrombosis in Patients With Inflammatory Bowel Disease

scientific article published on 18 March 2020

The efficacy and safety of direct oral anticoagulants in noncirrhotic portal vein thrombosis

scientific article published on 01 February 2020

The future of JAK inhibition in myelofibrosis and beyond

scientific article published on 28 June 2014

The presence of JAK2V617F mutation in the liver endothelial cells of patients with Budd-Chiari syndrome

scientific article

The role of anticoagulation in pylephlebitis: a retrospective examination of characteristics and outcomes

scientific article published on 01 February 2020

The utility of thrombophilia testing in patients with newly diagnosed portal vein thrombosis

scientific article published on 25 February 2020

Transient expansion of TP53 mutated clones in polycythemia vera patients treated with idasanutlin

scientific article published on 01 November 2020

Treatment with the Bcl-xL inhibitor ABT-737 in combination with interferon α specifically targets JAK2V617F-positive polycythemia vera hematopoietic progenitor cells

scientific article

Venetoclax and hypomethylating agent combination therapy in acute myeloid leukemia secondary to a myeloproliferative neoplasm

scientific article published on 22 September 2020

Why Does My Patient Have Erythrocytosis? ⬇️

scientific article published on April 1, 2012

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