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List of works by Benedict Seddon

A Zap70-dependent feedback circuit is essential for efficient selection of CD4 lineage thymocytes

scientific article published on 20 January 2015

Age is not just a number: Naive T cells increase their ability to persist in the circulation over time.

scientific article published on 11 April 2018

CD4+CD8- thymocytes that express L-selectin protect rats from diabetes upon adoptive transfer

scientific article published on 01 November 1996

Deaggregated homologous immunoglobulin-peptide conjugates induce peptide-specific T cell nonresponsiveness in vivo

scientific article published on 01 December 1998

Differential impact of self and environmental antigens on the ontogeny and maintenance of CD4 T cell memory

scientific article published on 19 November 2019

Differential requirement for IL-2 and IL-15 during bifurcated development of thymic regulatory T cells

scientific article published on 27 October 2014

Empowering T helper 17 cells in autoimmunity

scientific article published on 01 February 2010

Evidence of STAT5-dependent and -independent routes to CD8 memory formation and a preferential role for IL-7 over IL-15 in STAT5 activation

scientific article

Exogenous amino acids are essential for interleukin-7 induced CD8 T cell growth. [corrected]

scientific article

Flip the coin: IL-7 and IL-7R in health and disease

scientific article published on 19 November 2019

Fyn regulates the duration of TCR engagement needed for commitment to effector function

scientific article published in October 2007

Homeostatic mechanisms in the control of autoimmunity.

scientific article published on December 1997

Homeostatic proliferation and IL-7R alpha expression do not correlate with enhanced T cell proliferation and protection in chronic mouse malaria

scientific article

IL-7 determines the homeostatic fitness of T cells by distinct mechanisms at different signalling thresholds in vivo.

scientific article published on 3 November 2011

IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes.

scientific article published on 22 February 2018

Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP Thymocytes

scientific article published on 01 May 2000

Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells

scientific article

Interleukin-7 influences FOXP3+CD4+ regulatory T cells peripheral homeostasis

scientific article

Memory CD4 T cell subsets are kinetically heterogeneous and replenished from naive T cells at high levels.

scientific article

NF-κB signaling mediates homeostatic maturation of new T cells.

scientific article published on 18 February 2014

Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma

scientific article published on 01 September 2021

Proteolysis of NF-kappaB1 p105 is essential for T cell antigen receptor-induced proliferation

scientific article

Regulation of peripheral T-cell homeostasis by receptor signalling

scientific article

Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC- cells and CD4(+)CD8(-) thymocytes

scientific article

Role of CD4+CD8- thymocytes in the prevention of autoimmune diabetes.

scientific article published on May 1997

Sensory adaptation in naive peripheral CD4 T cells

scientific article

Spatial heterogeneity and peptide availability determine CTL killing efficiency in vivo.

scientific article

Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB

scholarly article by Louise V Webb et al published 19 February 2019 in Immunity

TCR and IL-7 receptor signals can operate independently or synergize to promote lymphopenia-induced expansion of naive T cells

scientific article published in October 2002

TCR signals mediated by Src family kinases are essential for the survival of naive T cells

scientific article published in September 2002

TNF activation of NF-κB is essential for development of single-positive thymocytes

scientific article published on 18 July 2016

Temporal fate mapping reveals age-linked heterogeneity in naive T lymphocytes in mice.

scientific article published on 25 November 2015

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.

scientific article

The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation

scientific article

The natural history of naive T cells from birth to maturity

scientific article published on 01 September 2018

The role of the thymus in the control of autoimmunity.

scientific article

The third function of the thymus.

scientific article

Thymic IL-7 signaling goes beyond survival.

scientific article published on April 2015

Tissue specific deletion of inhibitor of kappa B kinase 2 with OX40-Cre reveals the unanticipated expression from the OX40 locus in skin epidermis

scientific article published on 21 February 2012

Zap70 is essential for long-term survival of naive CD8 T cells

scientific article

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