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List of works by Tatsuji Nishihara

A new automatic device for measuring the spinnbarkeit of saliva: the Neva Meter

scientific article published in May 2004

A. actinomycetemcomitans LPS enhances foam cell formation induced by LDL.

scientific article published on 14 January 2013

Actinobacillus actinomycetemcomitans Y4 capsular-polysaccharide-like polysaccharide promotes osteoclast-like cell formation by interleukin-1 alpha production in mouse marrow cultures

scientific article

Actinobacillus actinomycetemcomitans induces apoptosis in human monocytic THP-1 cells.

scientific article published on March 2005

Actinobacillus actinomycetemcomitans lipopolysaccharide stimulates collagen phagocytosis by human gingival fibroblasts.

scientific article published in June 2008

Actinobacillus actinomycetemcomitans toxin induces both cell cycle arrest in the G2/M phase and apoptosis

scientific article

Activin A induces apoptotic cell death

scientific article

Activin A induction of cell-cycle arrest involves modulation of cyclin D2 and p21CIP1/WAF1 in plasmacytic cells

scientific article published on 01 July 1997

Activin A-induced apoptosis is suppressed by BCL-2.

scientific article published on December 1995

Aggregatibacter actinomycetemcomitans Invasion Induces Interleukin-1β Production Through Reactive Oxygen Species and Cathepsin B.

scientific article published on 19 March 2015

Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages

scientific article published on 10 March 2017

Ameloblastin and enamelin prevent osteoclast formation by suppressing RANKL expression via MAPK signaling pathway.

scientific article published on February 2017

Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T-cell cytoplasmic 1 (NFATc1)

scientific article published on 13 August 2018

An osteonecrosis model induced by oral bisphosphonate in ovariectomised rats.

scientific article published on September 2015

Antimicrobial effect of ozonated water on bacteria invading dentinal tubules

scientific article

Apoptosis and survivability of human dental pulp cells under exposure to Bis-GMA.

scientific article published on May 2011

Association of cortisol and dehydroepiandrosterone sulphate levels in serum with periodontal status in older Japanese adults

scientific article published on 24 August 2008

Bactericidal Effects of Diode Laser Irradiation on Enterococcus faecalis Using Periapical Lesion Defect Model.

scientific article

Bone morphogenetic protein-2 enhances osteoclast formation mediated by interleukin-1alpha through upregulation of osteoclast differentiation factor and cyclooxygenase-2.

scientific article published in May 1999

Caspases (interleukin-1beta-converting enzyme family proteases) are involved in the regulation of the survival of osteoclasts

scientific article published in July 1998

Compressive mechanical stress promotes osteoclast formation through RANKL expression on synovial cells.

scientific article published on 5 October 2006

Continuous fever-range heat stress induces thermotolerance in odontoblast-lineage cells

scientific article published on 18 April 2014

Correlation between Bcl-X expression and B-cell hybridoma apoptosis induced by activin A

scientific article published on 01 July 1998

Correlations between health status and OralChroma™-determined volatile sulfide levels in mouth air of the elderly.

scientific article published on 22 September 2011

Corrigendum to "Effect of dexmedetomidine on intraocular pressure in patients undergoing robot-assisted laparoscopic radical prostatectomy under total intravenous anesthesia: A randomized, double blinded placebo controlled clinical trial" J. Clin. An

scientific article published on 06 October 2018

Dectin-1-mediated suppression of RANKL-induced osteoclastogenesis by glucan from baker's yeast

scientific article published on 11 December 2020

Delivery of cytolethal distending toxin B induces cell cycle arrest and apoptosis in gingival squamous cell carcinoma in vitro.

scientific article published on October 2004

Dermatan sulfate inhibits osteoclast formation by binding to receptor activator of NF-kappa B ligand

scientific article published on 10 January 2007

Detection of subgingival calculus and dentine caries by laser fluorescence.

scientific article

Development of a membrane-based microwave-mediated electrochemical ELISA method for TNF-α detection in patients with periodontitis

scientific article

Diagnosis of Periodontal Disease from Saliva Samples Using Fourier Transform Infrared Microscopy Coupled with Partial Least Squares Discriminant Analysis

scientific article published in January 2016

Differential inhibition of Smad6 and Smad7 on bone morphogenetic protein- and activin-mediated growth arrest and apoptosis in B cells

scientific article (publication date: 7 May 1999)

Dissociation of bone morphogenetic protein-mediated growth arrest and apoptosis of mouse B cells by HPV-16 E6/E7

scientific article published on 01 May 2000

Dual effects of heparin on BMP-2-induced osteogenic activity in MC3T3-E1 cells.

scientific article published on January 2011

Effects of heat stress and starvation on clonal odontoblast-like cells

scientific article published on 24 May 2011

Effects of lipopolysaccharide on newly established rat dental pulp-derived cell line with odontoblastic properties

scientific article

Effects of sequential exposure to lipopolysaccharide and heat stress on dental pulp cells.

scientific article published on October 2006

Efficacy of ozone on survival and permeability of oral microorganisms.

scientific article

Enamel matrix derivative promotes osteoclast cell formation by RANKL production in mouse marrow cultures

scientific article

Enhanced phagocytosis of Aggregatibacter actinomycetemcomitans cells by macrophages activated by a probiotic Lactobacillus strain

scientific article published on 18 April 2018

Enumeration of viable Enterococcus faecalis, a predominant apical periodontitis pathogen, using propidium monoazide and quantitative real-time polymerase chain reaction.

scientific article

Epidermal growth factor receptor-targeted sonoporation with microbubbles enhances therapeutic efficacy in a squamous cell carcinoma model.

scientific article published on 22 September 2017

Essential Role of Lysophosphatidylcholine Acyltransferase 3 in the Induction of Macrophage Polarization in PMA-Treated U937 Cells.

scientific article

Essential role of JAK/STAT pathway in the induction of cell cycle arrest in macrophages infected with periodontopathic bacterium Aggregatibacter actinomycetemcomitans

scientific article

Essential role of mitogen-activated protein kinases in IL-17A-induced MMP-3 expression in human synovial sarcoma cells.

scientific article published on 5 February 2016

Evidence for apoptosis of murine macrophages by Actinobacillus actinomycetemcomitans infection

scientific article

Factors associated with dry mouth in dependent Japanese elderly.

scientific article published on 7 June 2012

Ferrocenylnaphthalene diimide-based electrochemical detection of aberrant methylation in hTERT gene.

scientific article published on 4 July 2014

Formation of dentin-like particles in dentin defects above exposed pulp by controlled release of fibroblast growth factor 2 from gelatin hydrogels

scientific article published in October 2007

Globular adiponectin-induced RAW 264 apoptosis is regulated by a reactive oxygen species-dependent pathway involving Bcl-2.

scientific article

Growth/differentiation factor-5 induces growth arrest and apoptosis in mouse B lineage cells with modulation by Smad.

scientific article published on February 2003

Heparin inhibits BMP-2 osteogenic bioactivity by binding to both BMP-2 and BMP receptor

scientific article published in September 2008

Heparin inhibits osteoclastic differentiation and function

scientific article published on April 2008

High molecular weight hyaluronic acid regulates MMP13 expression in chondrocytes via DUSP10/MKP5.

scientific article published on 21 April 2016

High molecular weight hyaluronic acid regulates osteoclast formation by inhibiting receptor activator of NF-κB ligand through Rho kinase.

scientific article published on November 2013

Human epithelial cell death caused by Actinobacillus actinomycetemcomitans infection

scientific article published in August 2000

IL-33 inhibits RANKL-induced osteoclast formation through the regulation of Blimp-1 and IRF-8 expression

scientific article published on 18 March 2015

Increase in Bcl-2 level promoted by CD40 ligation correlates with inhibition of B cell apoptosis induced by vacuolar type H(+)-ATPase inhibitor

scientific article published on 01 January 1998

Induction of the immune response to periodontopathic bacteria and its role in the pathogenesis of periodontitis

scientific article published on June 1997

Inhibition of adjuvant arthritis in rats by electroporation with interleukin-1 receptor antagonist

scientific article published on 22 August 2011

Inhibition of experimental bone resorption and osteoclast formation and survival by 2-aminoethanesulphonic acid

scientific article published on 01 September 1999

Inhibitory effect of lipopolysaccharide on apoptotic cell death in macrophages infected with Actinobacillus actinomycetemcomitans

scientific article published on June 1999

Inhibitory effects of ameloblastin on epithelial cell proliferation.

scientific article

Involvement of adhesion molecule in in vitro plaque-like formation of macrophages stimulated with Aggregatibacter actinomycetemcomitans lipopolysaccharide

scientific article published on 19 April 2010

Involvement of caspase activation through release of cytochrome c from mitochondria in apoptotic cell death of macrophages infected with Actinobacillus actinomycetemcomitans

scientific article published on April 2004

Involvement of caspases in apoptotic cell death of murine macrophages infected with Actinobacillus actinomycetemcomitans

scientific article published on February 2001

Involvement of cytochrome c and caspases in apoptotic cell death of human submandibular gland ductal cells induced by concanamycin A.

scientific article

Involvement of ganglioside GM3 in G(2)/M cell cycle arrest of human monocytic cells induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin

scientific article published on August 2005

Involvement of prostaglandin E2 and interleukin-1 alpha in the differentiation and survival of osteoclasts induced by lipopolysaccharide from Actinobacillus actinomycetemcomitans Y4

scientific article published on 01 November 1998

Involvement of tumor necrosis factor-alpha and interleukin-8 in antigen-induced arthritis of the rabbit temporomandibular joint

scientific article published on 01 February 2004

Ky-2, a hybrid compound histone deacetylase inhibitor, regulated inflammatory response in LPS-driven human macrophages

scientific article published on 05 October 2018

Lipopolysaccharide aggravates bisphosphonate-induced osteonecrosis in rats

scientific article published on 22 November 2014

Local delivery system of cytotoxic agents to tumors by focused sonoporation.

scientific article published on 2 February 2007

Local regeneration of dentin-pulp complex using controlled release of fgf-2 and naturally derived sponge-like scaffolds.

scientific article

Lysophosphatidylcholine acyltransferase 4 is involved in chondrogenic differentiation of ATDC5 cells

scientific article published in December 2017

Lysophosphatidylethanolamine acyltransferase 1/membrane-bound O-acyltransferase 1 regulates morphology and function of P19C6 cell-derived neurons.

scientific article published on 05 April 2016

Measurement of plaque-forming macrophages activated by lipopolysaccharide in a micro-channel chip.

scientific article

Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts.

scientific article published in August 2007

Mechanism involved in enhancement of osteoblast differentiation by hyaluronic acid

scientific article published on 23 January 2011

Mechanisms involved in enhancement of osteoclast formation and function by low molecular weight hyaluronic acid.

scientific article

Mechanisms involved in enhancement of osteoclast formation by activin-A.

scientific article

Mechanisms involved in inhibition of chondrogenesis by activin-A.

scientific article published on 8 March 2012

Mechanisms involved in regulation of osteoclastic differentiation by mechanical stress-loaded osteoblasts

scientific article published on April 2011

Mechanisms involved in suppression of ADAMTS4 expression in synoviocytes by high molecular weight hyaluronic acid

scientific article published on 28 February 2013

Mechanisms involved in suppression of NGF-induced neuronal differentiation of PC12 cells by hyaluronic acid

scientific article published on 15 July 2009

Mechanisms involved in the enhancement of osteoclast formation by enamel matrix derivative.

scientific article published on August 2006

Mechanisms of G1 cell cycle arrest and apoptosis in myeloma cells induced by hybrid-compound histone deacetylase inhibitor

scientific article published on 26 March 2013

Membrane-associated interleukin-1 on macrophages stimulated with Actinobacillus actinomycetemcomitans lipopolysaccharide induces osteoclastic bone resorption in vivo.

scientific article published on January 1995

Membrane-associated interleukin-1 promotes osteoclast-like cell formation in vitro.

scientific article published on April 1994

Microbial etiology of periodontitis

scientific article published in January 2004

Microbicidal efficacy of ozonated water against Candida albicans adhering to acrylic denture plates.

scientific article published in August 2005

Molecular and immunological characterization of a 64-kDa protein of Actinobacillus actinomycetemcomitans

scientific article

Morphological features of cartilage observed during mandibular distraction in rabbits

scientific article published on 04 December 2006

Nitric oxide-mediated protection of A. actinomycetemcomitans-infected murine macrophages against apoptosis

scientific article published on February 2002

Novel biological activity of ameloblastin in enamel matrix derivative.

scientific article

Oral cancer diagnosis via a ferrocenylnaphthalene diimide-based electrochemical telomerase assay.

scientific article

Osteoclast differentiation is associated with transient upregulation of cyclin-dependent kinase inhibitors p21(WAF1/CIP1) and p27(KIP1)

scientific article published on 01 January 2001

Ozonated water improves lipopolysaccharide-induced responses of an odontoblast-like cell line.

scientific article

Perspectives on a new educational system for dental hygiene students in Japan

scientific article published on 01 April 2011

Physical fitness and 6.5-year mortality in an 85-year-old community-dwelling population.

scientific article

Physicochemical properties of newly developed bioactive glass cement and its effects on various cells.

scientific article published on 3 June 2014

Platelet-rich plasma enhances human osteoblast-like cell proliferation and differentiation.

scientific article published on March 2005

Platelet-rich plasma enhances the differentiation of dental pulp progenitor cells into odontoblasts.

scientific article published on 23 February 2015

Possible Involvement of Smad Signaling Pathways in Induction of Odontoblastic Properties in KN-3 Cells by Bone Morphogenetic Protein-2: A Growth Factor to Induce Dentin Regeneration

scientific article published on 28 February 2012

Possible involvement of protein kinase C in apoptotic cell death of macrophages infected with Actinobacillus actinomycetemcomitans

scientific article

Possible involvement of protein kinases and Smad2 signaling pathways on osteoclast differentiation enhanced by activin A.

scientific article

Potential role of high molecular weight hyaluronan in the anti-Candida activity of human oral epithelial cells

scientific article published in February 2007

Prevalence of Actinobacillus actinomycetemcomitans serotypes in Japanese patients with periodontitis

scientific article published in November 1997

Promoting effects of thymosin β4 on granulation tissue and new bone formation after tooth extraction in rats

scientific article published on 26 August 2011

Quantitative discrimination of Aggregatibacter actinomycetemcomitans highly leukotoxic JP2 clone from non-JP2 clones in diagnosis of aggressive periodontitis

scientific article

Re-oxygenation improves hypoxia-induced pulp cell arrest.

scientific article published in September 2006

Relationship between TNF-alpha and TUNEL-positive chondrocytes in antigen-induced arthritis of the rabbit temporomandibular joint

scientific article published on 01 February 2006

Role of CD14 molecules in internalization of Actinobacillus actinomycetemcomitans by macrophages and subsequent induction of apoptosis

scientific article published on April 1997

Role of TGF-beta family in osteoclastogenesis induced by RANKL.

scientific article

Role of caspases in cleavage of lamin A/C and PARP during apoptosis in macrophages infected with a periodontopathic bacterium

scientific article

Role of heme oxygenase-1 in inflammatory response induced by mechanical stretch in synovial cells

scientific article published on 20 May 2011

Role of prostaglandin in the formation of osteoclasts induced by capsular-like polysaccharide antigen of Actinobacillus actinomycetemcomitans strain Y4.

scientific article published in April 1995

SC-19220, antagonist of prostaglandin E2 receptor EP1, inhibits osteoclastogenesis by RANKL.

scientific article published on 18 October 2004

Specific inhibitors of vacuolar H(+)-ATPase trigger apoptotic cell death of osteoclasts

scientific article published on 01 July 1997

Specific inhibitors of vacuolar type H(+)-ATPases induce apoptotic cell death.

scientific article

Spheroid culture enhances osteogenic potential of periodontal ligament mesenchymal stem cells

scientific article published on 14 June 2018

Streptococcus sanguinis induces foam cell formation and cell death of macrophages in association with production of reactive oxygen species.

scientific article

Targeted drug delivery system for oral cancer therapy using sonoporation.

scientific article

Tensile mechanical strain up-regulates Runx2 and osteogenic factor expression in human periosteal cells: implications for distraction osteogenesis

scientific article published on 01 April 2005

The G1 cell cycle arrest of macrophages infected with Aggregatibacter actinomycetemcomitans

scientific article published on April 2010

The dectin 1 agonist curdlan regulates osteoclastogenesis by inhibiting nuclear factor of activated T cells cytoplasmic 1 (NFATc1) through Syk kinase.

scientific article

The effects of low-intensity pulsed ultrasound exposure on gingival cells.

scientific article published on 22 February 2011

The role of activin type I receptors in activin A-induced growth arrest and apoptosis in mouse B-cell hybridoma cells

scientific article

Thermotolerance of pulp cells and phagocytosis of apoptotic pulp cells by surviving pulp cells following heat stress.

scientific article

Transient co-localization of c-Jun N-terminal kinase and c-Jun with heat shock protein 70 in pulp cells during apoptosis

scientific article published on 01 February 2003

Two different types of humoral immune response to Actinobacillus actinomycetemcomitans in high-responder periodontitis patients

scientific article published on 01 July 1998

Usefulness of new wetness tester for diagnosis of dry mouth in disabled patients

scientific article published in December 2004

Zoledronic acid exacerbates inflammation through M1 macrophage polarization.

scientific article

[Activin A induces apoptotic cell death of myeloma cells]

scientific article published on 01 July 1996

p53-independent expression of p21(CIP1/WAF1) in plasmacytic cells during G(2) cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin.

scientific article