List of works - Quan Fang

Activation of NPFF2 receptor stimulates neurite outgrowth in Neuro 2A cells through activation of ERK signaling pathway

scientific article published on 23 September 2016

Analgesic activities of the mixed opioid and NPFF receptors agonist DN-9 in a mouse model of formalin-induced orofacial inflammatory pain

scientific article published on 01 November 2018

Analgesic tolerance and cross-tolerance to the cannabinoid receptors ligands hemopressin, VD-hemopressin(α) and WIN55,212-2 at the supraspinal level in mice.

scientific article published on 7 July 2014

Antinociceptive effects of central administration of the endogenous cannabinoid receptor type 1 agonist VDPVNFKLLSH-OH [(m)VD-hemopressin(α)], an N-terminally extended hemopressin peptide.

scientific article published on 4 December 2013

Antinociceptive effects of the endogenous cannabinoid peptide agonist VD-hemopressin(β) in mice

scientific article published on 6 February 2018

BN-9, a chimeric peptide with mixed opioid and neuropeptide FF receptor agonistic properties, produces nontolerance-forming antinociception in mice

scientific article published on 28 March 2016

CB1 cannabinoid receptor agonist mouse VD-hemopressin(α) produced supraspinal analgesic activity in the preclinical models of pain

scientific article published on 21 December 2017

Cardiovascular effects of intravenous administered 26RFa, a novel RFamide peptide ligand for GPR103, in anaesthetised rats.

scientific article published on 8 September 2009

Central administration of neuropeptide FF and related peptides attenuate systemic morphine analgesia in mice

scientific article published on 01 April 2011

Central administrations of hemopressin and related peptides inhibit gastrointestinal motility in mice.

scientific article

Central and peripheral modulation of gastrointestinal transit in mice by DN-9, a multifunctional opioid/NPFF receptor agonist

scientific article published on 12 April 2020

Effects of neuropeptide FF system on CB₁ and CB₂ receptors mediated antinociception in mice

scientific article published on 19 September 2011

GpTx-1 and [Ala5 , Phe6 , Leu26 , Arg28 ]GpTx-1, two peptide NaV 1.7 inhibitors: analgesic and tolerance properties at the spinal level

scientific article published on 09 September 2018

In vitro and in vivo studies of dansylated compounds, the putative agonists and antagonists on neuropeptide FF receptors

scientific article published on 07 December 2005

In vivo inhibition of neuropeptide FF agonism by BIBP3226, an NPY Y1 receptor antagonist

scientific article (publication date: September 2006)

Inhibition of neuropeptide FF (NPFF)-induced hypothermia and anti-morphine analgesia by RF9, a new selective NPFF receptors antagonist

scientific article

NPFF2 receptor is involved in the modulatory effects of neuropeptide FF for macrophage cell line

scientific article published on May 2014

Neuropeptide FF activates ERK and NF kappa B signal pathways in differentiated SH-SY5Y cells.

scientific article

Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice.

scientific article

Neuropeptide FF attenuates the acquisition and the expression of conditioned place aversion to endomorphin-2 in mice.

scientific article

Neuropeptide FF receptor antagonist, RF9, attenuates the fever induced by central injection of LPS in mice ⬇️

scientific article published on December 16, 2010

Neuropeptide FF receptors antagonist, RF9, attenuates opioid-evoked hypothermia in mice

scientific article

Neuropeptide VF Enhances Cannabinoid Agonist WIN55,212-2-Induced Antinociception in Mice

scientific article published on 01 November 2015

Peripheral and central sites of action for anti-allodynic activity induced by the bifunctional opioid/NPFF receptors agonist BN-9 in inflammatory pain model

scientific article

Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance

scientific article published on 9 March 2016

Pharmacological characterization of rat VD-hemopressin(α), an α-hemoglobin-derived peptide exhibiting cannabinoid agonist-like effects in mice

scientific article published on 16 December 2016

Pharmacological effects of the dansylated neuropeptide FF analogues on body temperature and morphine analgesia

scientific article published on 26 June 2007

Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines

scientific article published on 15 November 2018

Pressor and tachycardic responses to intrathecal administration of neuropeptide FF in anesthetized rats.

scientific article published on 14 November 2009

Structure-Based Optimization of Multifunctional Agonists for Opioid and Neuropeptide FF Receptors with Potent Nontolerance Forming Analgesic Activities

scientific article

Study in vitro and in vivo of nociceptin/orphanin FQ(1-13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3.

scientific article published in August 2004

Synthesis and Biological Characterization of Cyclic Disulfide-Containing Peptide Analogs of the Multifunctional Opioid/Neuropeptide FF Receptor Agonists That Produce Long-Lasting and Nontolerant Antinociception

scientific article published on 03 December 2020

Systemic administration of the bifunctional opioid/neuropeptide FF receptors agonist BN-9 produced peripheral antinociception in preclinical mouse models of pain

scientific article published on 30 August 2018

TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.

scientific article

The anti-inflammatory potential of neuropeptide FF in vitro and in vivo.

scientific article published on 12 July 2013

The hypotensive effect of intrathecally injected (m)VD-hemopressin(α) in urethane-anesthetized rats.

scientific article published on 26 March 2014

The multifunctional peptide DN-9 produced peripherally acting antinociception in inflammatory and neuropathic pain via μ- and κ-opioid receptors

scientific article published on 23 December 2019

Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch.

scientific article published on 9 March 2016

List of works by Quan Fang

Activation of NPFF2 receptor stimulates neurite outgrowth in Neuro 2A cells through activation of ERK signaling pathway

Analgesic activities of the mixed opioid and NPFF receptors agonist DN-9 in a mouse model of formalin-induced orofacial inflammatory pain

Analgesic tolerance and cross-tolerance to the cannabinoid receptors ligands hemopressin, VD-hemopressin(α) and WIN55,212-2 at the supraspinal level in mice.

Antinociceptive effects of central administration of the endogenous cannabinoid receptor type 1 agonist VDPVNFKLLSH-OH [(m)VD-hemopressin(α)], an N-terminally extended hemopressin peptide.

Antinociceptive effects of the endogenous cannabinoid peptide agonist VD-hemopressin(β) in mice

BN-9, a chimeric peptide with mixed opioid and neuropeptide FF receptor agonistic properties, produces nontolerance-forming antinociception in mice

CB1 cannabinoid receptor agonist mouse VD-hemopressin(α) produced supraspinal analgesic activity in the preclinical models of pain

Cardiovascular effects of intravenous administered 26RFa, a novel RFamide peptide ligand for GPR103, in anaesthetised rats.

Central administration of neuropeptide FF and related peptides attenuate systemic morphine analgesia in mice

Central administrations of hemopressin and related peptides inhibit gastrointestinal motility in mice.

Central and peripheral modulation of gastrointestinal transit in mice by DN-9, a multifunctional opioid/NPFF receptor agonist

Effects of neuropeptide FF system on CB₁ and CB₂ receptors mediated antinociception in mice

GpTx-1 and [Ala5 , Phe6 , Leu26 , Arg28 ]GpTx-1, two peptide NaV 1.7 inhibitors: analgesic and tolerance properties at the spinal level

In vitro and in vivo studies of dansylated compounds, the putative agonists and antagonists on neuropeptide FF receptors

In vivo inhibition of neuropeptide FF agonism by BIBP3226, an NPY Y1 receptor antagonist

Inhibition of neuropeptide FF (NPFF)-induced hypothermia and anti-morphine analgesia by RF9, a new selective NPFF receptors antagonist

NPFF2 receptor is involved in the modulatory effects of neuropeptide FF for macrophage cell line

Neuropeptide FF activates ERK and NF kappa B signal pathways in differentiated SH-SY5Y cells.

Neuropeptide FF and related peptides attenuates warm-, but not cold-water swim stress-induced analgesia in mice.

Neuropeptide FF attenuates the acquisition and the expression of conditioned place aversion to endomorphin-2 in mice.

Neuropeptide FF receptor antagonist, RF9, attenuates the fever induced by central injection of LPS in mice ⬇️

Neuropeptide FF receptors antagonist, RF9, attenuates opioid-evoked hypothermia in mice

Neuropeptide VF Enhances Cannabinoid Agonist WIN55,212-2-Induced Antinociception in Mice

Peripheral and central sites of action for anti-allodynic activity induced by the bifunctional opioid/NPFF receptors agonist BN-9 in inflammatory pain model

Pharmacological characterization of EN-9, a novel chimeric peptide of endomorphin-2 and neuropeptide FF that produces potent antinociceptive activity and limited tolerance

Pharmacological characterization of rat VD-hemopressin(α), an α-hemoglobin-derived peptide exhibiting cannabinoid agonist-like effects in mice

Pharmacological effects of the dansylated neuropeptide FF analogues on body temperature and morphine analgesia

Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines

Pressor and tachycardic responses to intrathecal administration of neuropeptide FF in anesthetized rats.

Structure-Based Optimization of Multifunctional Agonists for Opioid and Neuropeptide FF Receptors with Potent Nontolerance Forming Analgesic Activities

Study in vitro and in vivo of nociceptin/orphanin FQ(1-13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3.

Synthesis and Biological Characterization of Cyclic Disulfide-Containing Peptide Analogs of the Multifunctional Opioid/Neuropeptide FF Receptor Agonists That Produce Long-Lasting and Nontolerant Antinociception

Systemic administration of the bifunctional opioid/neuropeptide FF receptors agonist BN-9 produced peripheral antinociception in preclinical mouse models of pain

TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor.

The anti-inflammatory potential of neuropeptide FF in vitro and in vivo.

The hypotensive effect of intrathecally injected (m)VD-hemopressin(α) in urethane-anesthetized rats.

The multifunctional peptide DN-9 produced peripherally acting antinociception in inflammatory and neuropathic pain via μ- and κ-opioid receptors

Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch.