Search filters

List of works by Tomasz Janecki

4-Methylideneisoxazolidin-5-ones--a new class of alpha-methylidene-gamma-lactones with high cytostatic activity.

scientific article published on 28 November 2005

A New Hybrid δ-Lactone Induces Apoptosis and Potentiates Anticancer Activity of Taxol in HL-60 Human Leukemia Cells

scientific article published on 25 March 2020

Anticancer Activity of New Synthetic α-Methylene-δ-Lactones on Two Breast Cancer Cell Lines

scientific article published on 18 September 2013

Anticancer activity and radiosensitization effect of methyleneisoxazolidin-5-ones in hepatocellular carcinoma HepG2 cells.

scientific article published on 8 February 2016

Anticancer activity of new molecular hybrids combining 1,4-naphthalenedione motif with phosphonic acid moiety in hepatocellular carcinoma HepG2 cells.

scientific article published on 4 November 2016

Anticancer properties of a new hybrid analog AD-013 combining a coumarin scaffold with an α-methylene-δ-lactone motif.

scientific article published on 21 September 2017

Anticancer properties of new synthetic hybrid molecules combining naphtho[2,3-b]furan-4,9-dione or benzo[f]indole-4,9-dione motif with phosphonate subunit

scientific article published on 3 May 2016

Anticancer properties of novel 4-methylene-1,2-diphenylpyrazolidin-3-ones.

scientific article published in April 2015

Antide B, an antagonist of LHRH with cis-3-(4-pyrazinylcarbonylaminocyclohexyl)alanine in position 5

scientific article published on 01 March 1995

Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines

scientific article published on 14 October 2012

Combined effects of anticancer drugs and new synthetic α-methylene-δ-lactones on MCF-7 cells.

scientific article

Comparison of anti-invasive activity of parthenolide and 3-isopropyl-2-methyl-4-methyleneisoxazolidin-5-one (MZ-6)--a new compound with α-methylene-γ-lactone motif--on two breast cancer cell lines.

scientific article published on 4 November 2011

Cyclic side-chain-linked opioid analogs utilizing cis- and trans-4-aminocyclohexyl-D-alanine

scientific article published in December 2014

Design, synthesis and cytotoxic evaluation of 4-methylidenepyrazolidin-3-ones

scientific article

Effect of 2′,6′-dimethyl-l-tyrosine (Dmt) on pharmacological activity of cyclic endomorphin-2 and morphiceptin analogs

scientific article published on 20 October 2011

Effective antagonists of luteinizing hormone releasing hormone modified at position one

scientific article published on 01 October 1993

Enantioselective synthesis and cytotoxic evaluation of 4,5-dihydro-5-[aryl(hydroxy)methyl]-3-methylidenefuran-2(3H)-ones.

scientific article published on September 2005

Enzymatic degradation studies of endomorphin-2 and its analogs containing N-methylated amino acids.

scientific article published on 8 August 2005

Involvement of a coumarin analog AD-013 in the DNA damage response pathways in MCF-7 cells

scholarly article by Angelika Długosz published in October 2018

Involvement of α-methylene-γ- and δ-lactones in the suppression of multidrug resistance in MCF-7 cells

scientific article published on 10 January 2018

Mechanistic and synthetic aspects of the reaction of gamma-halogeno-alpha,beta-unsaturated ketones and esters with simple trialkyl phosphites.

scientific article published in August 2003

New Chiral Ebselen Analogues with Antioxidant and Cytotoxic Potential.

scientific article

New glutathione peroxidase mimetics-Insights into antioxidant and cytotoxic activity.

scientific article published on 18 October 2016

New stereocontrolled synthesis and biological evaluation of 5-(1'-hydroxyalkyl)-3-methylidenetetrahydro-2-furanones as potential cytotoxic agents.

scientific article published in February 2002

New uracil analog with exocyclic methylidene group as potential anticancer agent

scientific article published on 10 December 2019

New, simple and versatile synthesis of 4,6-disubstituted pyridazin-3(2H)-ones

scientific article published on 28 February 2008

Novel highly potent mu-opioid receptor antagonist based on endomorphin-2 structure

scientific article

Novel synthesis, cytotoxic evaluation, and structure-activity relationship studies of a series of alpha-alkylidene-gamma-lactones and lactams.

scientific article

Opioid receptors and their ligands

scientific article

Pharmacological properties of novel cyclic pentapeptides with µ-opioid receptor agonist activity

scientific article

Reduced-Size Antagonists of Luteinizing Hormone-Releasing Hormone Active in Vitro ⬇️

scientific article published on July 21, 1995

Ring size in cyclic endomorphin-2 analogs modulates receptor binding affinity and selectivity.

scientific article published in June 2015

Supramolecular architecture in azaheterocyclic phosphonates. III. Structures of an ethyl phosphonamidate and an ethyl phosphonate

scientific article published on 13 July 2018

Synthesis and Anticancer Properties of New 3-Methylidene-1-sulfonyl-2,3-dihydroquinolin-4(1H)-ones

scientific article published in 2022

Synthesis and Cytotoxic Evaluation of 3-Methylidenechroman-4-ones

scientific article published on 15 May 2019

Synthesis and biological activity of N-methylated analogs of endomorphin-2

scientific article published on 06 September 2005

Synthesis and biological evaluation of 4-methylideneisoxazolidin-5-ones--a new class of highly cytotoxic alpha-methylidene-gamma-lactones

scientific article published on 25 October 2006

Synthesis and cytotoxic activity of gamma-aryl substituted alpha-alkylidene-gamma-lactones and alpha-alkylidene-gamma-lactams.

scientific article

Synthesis and cytotoxic evaluation of beta-alkyl or beta-aryl-delta-methyl-alpha-methylene-delta-lactones. Comparison with the corresponding gamma-lactones.

scientific article

Synthesis of 2,2,6-Trisubstituted 5-Methylidene-tetrahydropyran-4-ones with Anticancer Activity

scientific article published on 30 January 2020

Synthesis of 3-Methylidene-1-tosyl-2,3-dihydroquinolin-4(1H)-ones as Potent Cytotoxic Agents

scientific article published on 08 August 2018

Synthesis of 4,4-Disubstituted 3-Methylidenechroman-2-ones as Potent Anticancer Agents.

scientific article

The structural features of effective antagonists of the luteinizing hormone releasing hormone

scientific article published on 01 June 1994

Paulina is supported by:

About Paulina

Help