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List of works by Tak Pan Wong

A Rapid Pipeline to Model Rare Neurodevelopmental Disorders with Simultaneous CRISPR/Cas9 Gene Editing

scientific article published on December 2016

A critical role for myosin IIb in dendritic spine morphology and synaptic function

scientific article published in January 2006

Antidepressive effects of targeting ELK-1 signal transduction.

scientific article

Astrocytes Control Glutamate Receptor Levels at Developing Synapses through SPARC–β-Integrin Interactions ⬇️

scientific article published on March 16, 2011

Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease

scientific article published on 9 August 2017

Dynamic regulation of NMDAR function in the adult brain by the stress hormone corticosterone ⬇️

scientific article published on March 6, 2012

Early Growth Response 1 (Egr-1) Regulates N-Methyl-d-aspartate Receptor (NMDAR)-dependent Transcription of PSD-95 and α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor (AMPAR) Trafficking in Hippocampal Primary Neurons.

scientific article

Generalization of Conditioned Auditory Fear is Regulated by Maternal Effects on Ventral Hippocampal Synaptic Plasticity.

scientific article

Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer's disease in old Bmi1+/- mice

scientific article published in Scientific Reports

Hippocampal long-term depression is required for the consolidation of spatial memory ⬇️

scientific article published on September 7, 2010

Impaired adrenergic-mediated plasticity of prefrontal cortical glutamate synapses in rats with developmental disruption of the ventral hippocampus

scientific article

Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model.

scientific article

It is all in the right amygdala: increased synaptic plasticity and perineuronal nets in male, but not female juvenile rat pups after exposure to early-life stress

scientific article published on 25 September 2020

Knockdown of prodynorphin gene prevents cognitive decline, reduces anxiety, and rescues loss of group 1 metabotropic glutamate receptor function in aging.

scientific article published in July 2013

Ligand-Dependent TrkA Activity in Brain Differentially Affects Spatial Learning and Long-Term Memory ⬇️

scientific article published on May 26, 2011

Loss of dysbindin-1, a risk gene for schizophrenia, leads to impaired group 1 metabotropic glutamate receptor function in mice.

scientific article published on 26 March 2015

Loss of quinone reductase 2 function selectively facilitates learning behaviors

scientific journal article

Maternal care differentially affects neuronal excitability and synaptic plasticity in the dorsal and ventral hippocampus

scientific article published on 19 January 2015

Morphological and functional changes in the preweaning basolateral amygdala induced by early chronic stress associate with anxiety and fear behavior in adult male, but not female rats.

scientific article

NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo

scientific article published in March 2007

Negative Memory Engrams in the Hippocampus Enhance the Susceptibility to Chronic Social Defeat Stress

scientific article published on 12 August 2019

Opposing alterations in excitation and inhibition of layer 5 medial prefrontal cortex pyramidal neurons following neonatal ventral hippocampal lesion.

scientific article

Prenatal immune activation interacts with stress and corticosterone exposure later in life to modulate N-methyl-d-aspartate receptor synaptic function and plasticity ⬇️

scientific article published on April 3, 2013

Prenatal immune activation potentiates endocannabinoid-related plasticity of inhibitory synapses in the hippocampus of adolescent rat offspring

scientific article published on 23 September 2018

Presynaptic D2 dopamine receptors control long-term depression expression and memory processes in the temporal hippocampus.

scientific article

Preventing synaptic deficits in Alzheimer's disease by inhibiting tumor necrosis factor alpha signaling

scientific article published on 02 February 2018

Primary Blast-Induced Changes in Akt and GSK3β Phosphorylation in Rat Hippocampus.

scientific article published on 18 August 2017

Simultaneous monitoring of presynaptic transmitter release and postsynaptic receptor trafficking reveals an enhancement of presynaptic activity in metabotropic glutamate receptor-mediated long-term depression.

scientific article published on March 2013

Synaptic numbers across cortical laminae and cognitive performance of the rat during ageing ⬇️

scientific article published on May 1, 1998

The impact of Aβ-plaques on cortical cholinergic and non-cholinergic presynaptic boutons in alzheimer's disease-like transgenic mice ⬇️

scientific article published on January 1, 2003

Trichinella spiralis: specificity of ES antigens from pre-encysted larvae

scientific article published on 01 March 1992

Variations in postnatal maternal care and the epigenetic regulation of metabotropic glutamate receptor 1 expression and hippocampal function in the rat

scientific article

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

scientific article

p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression

scientific article published on 09 September 2019

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