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List of works by Fiona E McCann

A genetics-led approach defines the drug target landscape of 30 immune-related traits

scientific article published on 28 June 2019

ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation

scientific journal article

ANTI-CD3 therapy expands the numbers of CD4+ and CD8+ Treg cells and induces sustained amelioration of collagen-induced arthritis

scientific article published on 01 January 2010

Anti-Tumour Necrosis Factor Therapy for Dupuytren's Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial

scientific article published on 06 July 2018

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis

scientific article published on 2 June 2010

Author Correction: Cellular census of human fibrosis defines functionally distinct stromal cell types and states

scientific article published on 24 June 2020

Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis.

scientific article published in September 2011

Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells

scientific article published on 20 October 2008

Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D

scientific article

Cellular census of human fibrosis defines functionally distinct stromal cell types and states

scientific article published on 02 June 2020

Control of immune responses by trafficking cell surface proteins, vesicles and lipid rafts to and from the immunological synapse

scientific article published in September 2004

Erratum

scholarly article published in Journal of Experimental Medicine

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production.

scientific article

Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis

scientific article published on 04 December 2019

Identification of an intestinal heme transporter

scientific journal article

Imaging immune surveillance by T cells and NK cells

scientific article

Inhibitory Receptor Signals Suppress Ligation-Induced Recruitment of NKG2D to GM1-Rich Membrane Domains at the Human NK Cell Immune Synapse

scientific article published on 01 May 2007

Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses

scientific article

Investigating the Role of Toll-Like Receptors in Models of Arthritis

scientific article published on 01 January 2016

Mapping tenascin-C interaction with toll-like receptor 4 reveals a new subset of endogenous inflammatory triggers.

scientific article published on 17 November 2017

Membranous structures transfer cell surface proteins across NK cell immune synapses

scientific article

New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast

scientific article

OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis.

scientific article published on 27 January 2014

Protocol for the induction of arthritis in C57BL/6 mice.

scientific article published in January 2008

Selective tumor necrosis factor receptor I blockade is antiinflammatory and reveals immunoregulatory role of tumor necrosis factor receptor II in collagen-induced arthritis

scientific article published in October 2014

Single cell force profiling of human myofibroblasts reveals a biophysical spectrum of cell states

scientific article published on 24 March 2020

TNF receptor 2 signaling prevents DNA methylation at the Foxp3 promoter and prevents pathogenic conversion of regulatory T cells

scientific article published on 09 October 2019

TNFR2 increases the sensitivity of ligand-induced activation of the p38 MAPK and NF-κB pathways and signals TRAF2 protein degradation in macrophages

scientific article published on 27 December 2013

Target Identification Using Chemical Probes

scientific article published on 24 October 2018

The activating NKG2D ligand MHC class I-related chain A transfers from target cells to NK cells in a manner that allows functional consequences.

scientific article published in March 2007

The protean immune cell synapse: a supramolecular structure with many functions.

scientific article published on December 2003

The size of the synaptic cleft and distinct distributions of filamentous actin, ezrin, CD43, and CD45 at activating and inhibitory human NK cell immune synapses

scientific article published on March 2003

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