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List of works by Jana Sawynok

5-Hydroxytryptamine releases adenosine from primary afferent nerve terminals in the spinal cord

scientific article published on 01 October 1988

8-Phenyltheophylline reverses the antinociceptive action of morphine in the periaqueductal gray ⬇️

scientific article published on August 1, 1991

A pilot trial of CFQ for treatment of fibromyalgia

scientific article published on 01 October 2009

A qualitative systematic review of head-to-head randomized controlled trials of oral analgesics in neuropathic pain

scientific article published on May 2010

A randomized controlled trial of qigong for fibromyalgia ⬇️

scientific article published on August 3, 2012

Acute amitriptyline in a rat model of neuropathic pain: differential symptom and route effects

scientific article published on 01 April 1999

Adenosine A1 receptor-dependent antinociception induced by inosine in mice: pharmacological, genetic and biochemical aspects.

scientific article published on 27 July 2014

Adenosine and ATP receptors.

scientific article published on January 2007

Adenosine in the spinal cord and periphery: release and regulation of pain

scientific article

Adenosine kinase inhibitors augment release of adenosine from spinal cord slices

scientific article published on 01 June 1996

Adenosine mediates calcium-induced antinociception and potentiation of noradrenergic antinociception in the spinal cord

scientific article published in August 1990

Adenosine receptor targets for pain

scientific article

Adrenergic regulation of P2X3 and TRPV1 receptors: differential effects of spared nerve injury

scientific article published on 15 August 2008

Alpha1-adrenergic receptors augment P2X3 receptor-mediated nociceptive responses in the uninjured state

scientific article published on 23 May 2007

Amitriptyline enhances extracellular tissue levels of adenosine in the rat hindpaw and inhibits adenosine uptake

scientific article published on August 2005

Amitriptyline neurotoxicity

scientific article published in January 2005

Amitriptyline produces multiple influences on the peripheral enhancement of nociception by P2X receptors

scientific article published in September 2004

Antinociception by adenosine analogs and an adenosine kinase inhibitor: dependence on formalin concentration

scientific article published on 01 November 1995

Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat ⬇️

scientific article published on 01 February 1998

Antinociception by systemically-administered acetaminophen (paracetamol) involves spinal serotonin 5-HT7 and adenosine A1 receptors, as well as peripheral adenosine A1 receptors.

scientific article published on 8 January 2013

Caffeine and pain ⬇️

scientific article published on October 30, 2010

Caffeine antinociception in the rat hot-plate and formalin tests and locomotor stimulation: involvement of noradrenergic mechanisms ⬇️

scientific article published on 01 May 1995

Caffeine antinociception: role of formalin concentration and adenosine A1 and A2 receptors

scientific article published on 01 March 1996

Caffeine inhibits antinociception by acetaminophen in the formalin test by inhibiting spinal adenosine A1 receptors ⬇️

scientific article published on 07 November 2011

Caffeine reverses antinociception by amitriptyline in wild type mice but not in those lacking adenosine A1 receptors

scientific article published on 24 May 2008

Caffeine reverses antinociception by oxcarbazepine by inhibition of adenosine A1 receptors: insights using knockout mice

scientific article published on 20 February 2010

Chaoyi Fanhuan Qigong and fibromyalgia: methodological issues and two case reports

scientific article published on 9 November 2012

Chronic intrathecal cannulas inhibit some and potentiate other behaviors elicited by formalin injection ⬇️

scientific article published on 01 May 2003

Classification of adenosine receptors mediating antinociception in the rat spinal cord

scientific article published on August 1986

Clonidine reverses baclofen-induced increases in noradrenaline turnover in rat brain

scientific article published in May 1986

Clonidine reverses methylxanthine-induced potentiation of baclofen antinociception

scientific article published on 01 May 1985

Contributions of peripheral, spinal, and supraspinal actions to analgesia.

scientific article published on 13 April 2014

D-Baclofen is an antagonist at baclofen receptors mediating antinociception in the spinal cord

scientific article published on 01 January 1985

D-baclofen: Is it an antagonist at baclofen receptors? ⬇️

scientific article published on 01 January 1984

Desensitization to substance P following intrathecal injection. A technique for investigating the role of substance P in nociception

scientific article published on 01 November 1985

Desipramine potentiates spinal antinociception by 5-hydroxytryptamine, morphine and adenosine

scientific article published on 01 July 1992

Effects of morphine and naloxone on the K+-stimulated release of methionine-enkephalin from slices of rat corpus striatum

scientific article published on 01 May 1980

Enhancement of clonidine-induced analgesia by lesions induced with spinal and intracerebroventricular administration of 5,7-dihydroxytryptamine

scientific article published on 01 April 1987

Evidence that substance P may be a modulator rather than a transmitter of noxious mechanical stimulation

scientific article published on 01 October 1986

Extension trial of qigong for fibromyalgia: a quantitative and qualitative study

scientific article published on 28 August 2013

Formalin-induced nociceptive behavior and edema: involvement of multiple peripheral 5-hydroxytryptamine receptor subtypes ⬇️

scientific article published on 01 October 1997

Gabaergic mechanisms in antinociception ⬇️

scientific article published on 01 January 1984

Influence of calcium on the release of endogenous adenosine from spinal cord synaptosomes

scientific article published on 01 January 1993

Intracerebroventricular morphine releases adenosine and adenosine 3',5'-cyclic monophosphate from the spinal cord via a serotonergic mechanism ⬇️

scientific article published on December 1, 1991

Intraplantar injection of glutamate evokes peripheral adenosine release in the rat hind paw: involvement of peripheral ionotropic glutamate receptors and capsaicin-sensitive sensory afferents

scientific article published in February 2002

Intrathecal but not intravenous opioids release adenosine from the spinal cord

scientific article published in February 2004

Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design ⬇️

scientific article published on May 1, 2003

Involvement of Calcium Channels in Depolarization‐Evoked Release of Adenosine from Spinal Cord Synaptosomes ⬇️

scientific article published on 01 March 1993

Involvement of GABA in the antinociceptive effect of gamma-acetylenic GABA (GAG), an inhibitor of GABA-transaminase

scientific article published on 01 January 1983

Lack of effect of baclofen on substance P and somatostatin release from the spinal cord in vitro ⬇️

scientific article published on 01 April 1982

Lesions to ascending noradrenergic and serotonergic pathways modify antinociception produced by intracerebroventricular administration of morphine

scientific article published on 01 February 1989

Methylxanthines and Pain ⬇️

scientific article published on January 1, 2011

Modulation of adenosine release from rat spinal cord by adenosine deaminase and adenosine kinase inhibitors

scientific article published on 01 November 1995

Modulation of formalin-induced behaviors and edema by local and systemic administration of dextromethorphan, memantine and ketamine

scientific article

Monoamines as mediators of the antinociceptive effect of baclofen

scientific article published on 01 June 1983

Morphine Activates ω‐Conotoxin‐Sensitive Ca2+ Channels to Release Adenosine from Spinal Cord Synaptosomes ⬇️

scientific article published on 01 March 1993

Morphine releases endogenous adenosine from the spinal cord in vivo

scientific article published on 01 September 1987

Naloxone antagonizes inhibitory and unmasks excitatory effects of baclofen ⬇️

scientific article published on September 1, 1981

Nontricyclic antidepressant analgesics and pain: are serotonin norepinephrine reuptake inhibitors (SNRIs) any better?

scientific article published on 30 June 2011

Noradrenergic and purinergic involvement in spinal antinociception by 5-hydroxytryptamine and 2-methyl-5-hydroxytryptamine

scientific article published on 01 November 1991

Noradrenergic mediation of spinal antinociception by 5-hydroxytryptamine: characterization of receptor subtypes

scientific article published on November 13, 1992

Pain Catastrophizing Predicts Poor Response to Topical Analgesics in Patients with Neuropathic Pain ⬇️

scientific article published on January 1, 2012

Pain behaviors produced by capsaicin: influence of inflammatory mediators and nerve injury

scientific article published in February 2006

Peripheral P2X receptors and nociception: interactions with biogenic amine systems

scientific article

Peripheral adenosine 5′-triphosphate enhances nociception in the formalin test via activation of a purinergic p2X receptor ⬇️

scientific article published on 01 July 1997

Peripheral amitriptyline suppresses formalin-induced Fos expression in the rat spinal cord

scientific article published in February 2002

Peripheral antihyperalgesic and analgesic actions of ketamine and amitriptyline in a model of mild thermal injury in the rat.

scientific article

Peripheral antinociceptive actions of desipramine and fluoxetine in an inflammatory and neuropathic pain test in the rat

scientific article published on 01 August 1999

Peripheral antinociceptive effect of an adenosine kinase inhibitor, with augmentation by an adenosine deaminase inhibitor, in the rat formalin test ⬇️

scientific article published on 01 January 1998

Peripheral interactions between dextromethorphan, ketamine and amitriptyline on formalin-evoked behaviors and paw edema in rats

scientific article published in March 2003

Perisurgical amitriptyline produces a preventive effect on afferent hypersensitivity following spared nerve injury

scientific article

Pertussis toxin inhibits antinociception produced by intrathecal injection of morphine, noradrenaline and baclofen

scientific article published on 01 January 1988

Plasma concentration and urinary excretion of guanidine derivatives in normal subjects and patients with renal failure ⬇️

scientific article published on January 1, 1975

Qigong and Fibromyalgia circa 2017.

scientific article published on 6 June 2017

Qigong and fibromyalgia: randomized controlled trials and beyond

scientific article

Qualitative analysis of a controlled trial of qigong for fibromyalgia: advancing understanding of an emerging health practice

scientific article published on 29 July 2014

Reduction of formalin-evoked responses and maintenance of peripheral antinociception by morphine against formalin in the spared nerve injury model ⬇️

scientific article published on April 25, 2011

Role of G-proteins and adenylate cyclase in antinociception produced by intrathecal purines

scientific article published on 01 October 1988

Role of ascending and descending serotonergic pathways in the antinociceptive effect of baclofen ⬇️

scientific article published on April 1, 1988

Spinal and peripheral adenosine A₁ receptors contribute to antinociception by tramadol in the formalin test in mice.

scientific article

Spinal serotonin 5-HT7 and adenosine A1 receptors, as well as peripheral adenosine A1 receptors, are involved in antinociception by systemically administered amitriptyline

scientific article published on 06 November 2012

Spinal supersensitivity to 5-HT1, 5-HT2 and 5-HT3 receptor agonists following 5,7-dihydroxytryptamine ⬇️

scientific article published on 01 November 1994

Substance P, injected intrathecally, antagonizes the spinal antinociceptive effect of morphine, baclofen and noradrenaline ⬇️

scientific article published on 01 July 1984

Supersensitivity to intrathecal 5-hydroxytryptamine, but not noradrenaline, following depletion of spinal 5-hydroxytryptamine by 5,7-dihydroxytryptamine administered into various sites

scientific article published on July 1990

The interaction between gabapentin and amitriptyline in the rat formalin test after systemic administration

scientific article published in April 2002

The therapeutic use of heroin: a review of the pharmacological literature

scientific article

Topical 2% amitriptyline and 1% ketamine in neuropathic pain syndromes: a randomized, double-blind, placebo-controlled trial

scientific article published in July 2005

Topical amitriptyline and ketamine for post-herpetic neuralgia and other forms of neuropathic pain

scientific article

Topical amitriptyline and ketamine in neuropathic pain syndromes: an open-label study

scientific article

Topical analgesics for neuropathic pain in the elderly: current and future prospects

scientific article

Topical analgesics for neuropathic pain: preclinical exploration, clinical validation, future development

scientific article

Topical analgesics in neuropathic pain

scientific article

Topical and peripheral ketamine as an analgesic

scientific article

Topical and peripherally acting analgesics

scientific article

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