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List of works by Jean Charron

Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1

scientific article

Analysis of deoxycytidine (dC) deaminase activity in herpes simplex virus-infected or HSV TK-transformed cells: association with mycoplasma contamination but not with virus infection.

scientific article published in November 1981

Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation.

scientific article published on January 2013

B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

scientific journal article

Bromodeoxyuridine resistance in CHO cells occurs in three discrete steps

scientific article published on 01 March 1982

Cooperative Action of Multiple cis-Acting Elements Is Required for N-myc Expression in Branchial Arches: Specific Contribution of GATA3.

scientific article

Cooperative action of multiple cis-acting elements is required for N-myc expression in branchial arches: specific contribution of GATA3

scientific journal article

Crucial requirement of ERK/MAPK signaling in respiratory tract development

scientific journal article

Defective development of the embryonic liver in N-myc-deficient mice.

scientific article published in March 1998

ERK (MAPK) does not phosphorylate tau under physiological conditions in vivo or in vitro.

scientific article published on 14 November 2014

Embryonic death of Mek1-deficient mice reveals a role for this kinase in angiogenesis in the labyrinthine region of the placenta

scientific journal article

Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene

scientific article published on December 1, 1992

Epithelial inactivation of Yy1 abrogates lung branching morphogenesis

scientific article published on September 2015

Essential role of the ERK/MAPK pathway in blood-placental barrier formation.

scientific article

Functional redundancy of the kinases MEK1 and MEK2: Rescue of the Mek1 mutant phenotype by Mek2 knock-in reveals a protein threshold effect.

scientific article

Generation of normal lymphocytes derived from N-myc-deficient embryonic stem cells

scientific article published in October 1995

Identification of N-myc regulatory regions involved in embryonic expression.

scientific article published in January 2002

Implication of MEK1 and MEK2 in the establishment of the blood-placenta barrier during placentogenesis in mouse

scientific article published on 03 March 2012

Lung development requires an active ERK/MAPK pathway in the lung mesenchyme.

scientific article published on 17 October 2016

MEK Is a Key Regulator of Gliogenesis in the Developing Brain.

scientific article published on September 2012

MEK1 dependent and independent ERK activation regulates IL-10 and IL-12 production in bone marrow derived macrophages.

scientific article published on 21 July 2015

MEK1 regulates pulmonary macrophage inflammatory responses and resolution of acute lung injury

scientific article published on 05 December 2019

MEK1/2 Inhibition Promotes Macrophage Reparative Properties

scientific article published on 21 December 2016

MEK2 Negatively Regulates Lipopolysaccharide-Mediated IL-1β Production through HIF-1α Expression

scientific article published on 01 February 2019

Map2k1 and Map2k2 genes contribute to the normal development of syncytiotrophoblasts during placentation.

scientific article published in April 2009

Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia.

scientific article published in April 2007

Mek1Y130C mice recapitulate aspects of human cardio-facio-cutaneous syndrome.

scientific article

Mek2 is dispensable for mouse growth and development

scientific journal article

Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion

scientific article

N-Myc shares cellular functions wiht c-Myc

scientific article published on 01 June 2000

Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions.

scientific article

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

scientific article published on March 6, 1992

Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.

scientific article published on 14 October 2013

Reduced fertility in male mice deficient in the zinc metallopeptidase NL1

scientific article

Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis.

scientific article published on 3 August 2006

Role of Plk2 (Snk) in mouse development and cell proliferation

scientific article published in October 2003

Selective role for Mek1 but not Mek2 in the induction of epidermal neoplasia.

scientific article published on 21 April 2009

Structure of the rat pro-opiomelanocortin (POMC) gene.

scientific article published in November 1985

The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility

scientific article

[Mek1 and Mek2 functions in the formation of the blood placental barrier].

scientific article

c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma

scientific article published on 21 April 2011