List of works by Stephen L. Hoffman

A CTL epitope on the circumsporozoite protein of P. yoelii

scientific article published on January 1990

A DNA vaccine encoding the 42 kDa C-terminus of merozoite surface protein 1 of Plasmodium falciparum induces antibody, interferon-gamma and cytotoxic T cell responses in rhesus monkeys: immuno-stimulatory effects of granulocyte macrophage-colony sti

scientific article published in April 2002

A Multivariate Study of the Effects of High-Risk Factors on Performance on the Brazelton Neonatal Assessment Scale

scientific article published on June 1, 1976

A T cell clone directed at the circumsporozoite protein which protects mice against both Plasmodium yoelii and Plasmodium berghei ⬇️

scientific article published on September 15, 1992

A double-blind, placebo-controlled phase 1/2a trial of the genetically attenuated malaria vaccine PfSPZ-GA1

scientific article published on 01 May 2020

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

scientific article

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite.

scientific article published on 19 March 2018

A malaria sporozoite surface antigen distinct from the circumsporozoite protein

scientific article

A microscale human liver platform that supports the hepatic stages of Plasmodium falciparum and vivax

scientific article published on July 2013

A monoclonal antibody directed against the sporozoite stage of Plasmodium vivax binds to liver parenchymal cells

scientific article published on August 1, 1992

A multilateral effort to develop DNA vaccines against falciparum malaria

scientific article

A plasmid encoding murine granulocyte-macrophage colony-stimulating factor increases protection conferred by a malaria DNA vaccine.

scientific article

A public antibody lineage that potently inhibits malaria infection through dual binding to the circumsporozoite protein.

scientific article

A randomized, double-blind, placebo-controlled, dose-ranging trial of tafenoquine for weekly prophylaxis against Plasmodium falciparum

scientific article published on 14 February 2003

A role for environmental factors in the production of digitalis toxicity

scientific article published in February 1980

A shotgun optical map of the entire Plasmodium falciparum genome

scientific article

A subdominant CD8(+) cytotoxic T lymphocyte (CTL) epitope from the Plasmodium yoelii circumsporozoite protein induces CTLs that eliminate infected hepatocytes from culture

scientific article

A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito

scientific article

Absence of antigenic competition in Aotus monkeys immunized with Plasmodium falciparum DNA vaccines delivered as a mixture

scientific article published in February 2002

Absence of malaria mortality in villagers with chloroquine-resistant Plasmodium falciparum treated with chloroquine

scientific article published on January 1984

Acquired antibody responses against Plasmodium vivax infection vary with host genotype for duffy antigen receptor for chemokines (DARC)

scientific article (publication date: 15 July 2010)

Acridine orange detection of Plasmodium falciparum malaria: relationship between sensitivity and optical configuration

scientific article published in April 1991

Acridine orange diagnosis of Plasmodium falciparum: evaluation after experimental infection

scientific article published in November 1994

Activation of TCR Vδ1+ and Vδ1-Vδ2- γδ T Cells upon Controlled Infection with Plasmodium falciparum in Tanzanian Volunteers

scientific article published on 04 December 2019

Adaptive clinical trials of three PfSPZ products for development of a whole sporozoite vaccine that prevents Plasmodium falciparum infection, disease and transmission.

scientific article

Addition of etoposide to cyclophosphamide, doxorubicin, and vincristine for remission induction and survival in patients with small cell lung cancer

scientific article published in January 1987

Advancing Global Health through Development and Clinical Trials Partnerships: A Randomized, Placebo-Controlled, Double-Blind Assessment of Safety, Tolerability, and Immunogenicity of PfSPZ Vaccine for Malaria in Healthy Equatoguinean Men.

scientific article published on 30 October 2017

Age-dependent susceptibility to severe disease with primary exposure to Plasmodium falciparum

scientific article

Alterations of blood coagulation in controlled human malaria infection

scientific article

Antibodies to the Circumsporozoite Protein and Protective Immunity to Malaria Sporozoites ⬇️

scientific article published on January 1, 1993

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

scientific article published in Science

Artemether in severe malaria--still too many deaths

scientific article published in July 1996

Assessing the Parasight-F test in northeastern Papua, Indonesia, an area of mixed Plasmodium falciparum and Plasmodium vivax transmission

scientific article

Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates

scientific article published on 16 February 2012

Assessment of Age-Dependent Immunity to Malaria in Transmigrants ⬇️

scientific article published on June 1, 1997

Atovaquone/proguanil therapy for Plasmodium falciparum and Plasmodium vivax malaria in Indonesians who lack clinical immunity

scientific article

Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection

scientific article published on 21 February 2017

Autologous lymphoblastoid cell lines stably transfected with Plasmodium falciparum circumsporozoite protein as targets in cytotoxic T-lymphocyte assays

scientific article published on March 1997

BAFF and BAFF receptor levels correlate with B cell subset activation and redistribution in controlled human malaria infection

scientific article

Beyond Blood Smears: Qualification of Plasmodium 18S rRNA as a Biomarker for Controlled Human Malaria Infections.

scientific article published in June 2019

Bone marrow aspirate culture superior to streptokinase clot culture and 8 ml 1:10 blood-to-broth ratio blood culture for diagnosis of typhoid fever

scientific article

Boosting of DNA vaccine-elicited gamma interferon responses in humans by exposure to malaria parasites

scientific article

Can malaria DNA vaccines on their own be as immunogenic and protective as prime-boost approaches to immunization?

scientific article published in January 2000

Cellular mechanisms of nonspecific immunity to intracellular infection: cytokine-induced synthesis of toxic nitrogen oxides from L-arginine by macrophages and hepatocytes

scientific article

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection

scientific article published on 13 October 2016

Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodium falciparum malaria

scientific article

Characteristics of severe anemia and its association with malaria in young children of the Kassena-Nankana district of northern Ghana.

scientific article published on October 2002

Characterization of the gene encoding sporozoite surface protein 2, a protective Plasmodium yoelii sporozoite antigen

scientific article published on July 1992

Chloroquine for the treatment of uncomplicated malaria in Guyana

scientific article published on June 2002

Chloroquine resistant Plasmodium falciparum on the island of Flores, Indonesia

scientific article published on January 1983

Chloroquine/doxycycline combination versus chloroquine alone, and doxycycline alone for the treatment of Plasmodium falciparum and Plasmodium vivax malaria in northeastern Irian Jaya, Indonesia

scientific article

Chromosome 2 sequence of the human malaria parasite Plasmodium falciparum

scientific article (publication date: 6 November 1998)

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity

scientific article

Clinical manifestations of Plasmodium falciparum malaria experimentally induced by mosquito challenge

scientific article

Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage Plasmodium falciparum DNA vaccine combined with escalating dose human GM-CSF DNA

scientific article published on November 2012

Comparative analysis of apicomplexa and genomic diversity in eukaryotes

scientific article published on September 2004

Comparative cost models of a liquid nitrogen vapor phase (LNVP) cold chain-distributed cryopreserved malaria vaccine vs. a conventional vaccine

scientific article published on 10 November 2012

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

scientific article

Comparative immunopeptidomics of humans and their pathogens

scholarly article

Complete protection against Plasmodium yoelii by adoptive transfer of a CD8+ cytotoxic T-cell clone recognizing sporozoite surface protein 2.

scientific article

Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA ⬇️

scientific article published on August 15, 1995

Construction and immunogenicity of DNA vaccine plasmids encoding four Plasmodium vivax candidate vaccine antigens

scientific article published in August 1999

Controlled Human Malaria Infection Leads to Long-Lasting Changes in Innate and Innate-like Lymphocyte Populations.

scientific article published on 2 June 2017

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

scientific article published on 7 August 2015

Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites

scientific article

Controlled human malaria infections by intradermal injection of cryopreserved Plasmodium falciparum sporozoites

scientific article published on 13 November 2012

Controlled human malaria infections using aseptic, purified cryopreserved Plasmodium falciparum sporozoites administered by needle and syringe

scientific article published on 22 September 2014

Corrigendum: Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article published in June 2016

CpG oligodeoxynucleotide and Montanide ISA 51 adjuvant combination enhanced the protective efficacy of a subunit malaria vaccine

scientific article published on February 2004

Cross-species malaria immunity induced by chemically attenuated parasites

scientific article

Cures for the Third World's problems: the application of genomics to the diseases plaguing the developing world may have huge medical and economic benefits for those countries and might even prevent armed conflict

scientific article

Cytotoxic T cell reactivity and HLA‐B35 binding of the variant Plasmodium falciparum circumsporozoite protein CD8+ CTL epitope in naturally exposed Kenyan adults ⬇️

scientific article published on August 1, 1997

Cytotoxic T cells recognize a peptide from the circumsporozoite protein on malaria-infected hepatocytes

scientific article

Cytotoxic T lymphocyte (CTL) adherence assay (CAA): a non-radioactive assay for murine CTL recognition of peptide-MHC class I complexes

scientific article published in February 1997

DNA inoculation with a plasmid vector carrying the hepatitis E virus structural protein gene induces immune response in mice

scientific article published in March 1997

DNA vaccines against malaria: immunogenicity and protection in a rodent model

scientific article published on December 1996

DNA-based vaccines against malaria: status and promise of the Multi-Stage Malaria DNA Vaccine Operation

scientific article

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

scientific article

Daily primaquine is effective for prophylaxis against falciparum malaria in Kenya: comparison with mefloquine, doxycycline, and chloroquine plus proguanil

scientific article published on June 1995

Degenerate Cytotoxic T Cell Epitopes from P. falciparum Restricted by Multiple HLA-A and HLA-B Supertype Alleles ⬇️

scientific article published on July 1, 1997

Delineation of stage specific expression of Plasmodium falciparum EBA-175 by biologically functional region II monoclonal antibodies

scientific article

Determining liver stage parasite burden by real time quantitative PCR as a method for evaluating pre-erythrocytic malaria vaccine efficacy

scientific article published in December 2001

Development of a Live Attenuated Bivalent Oral Vaccine Against Shigella sonnei Shigellosis and Typhoid Fever

scientific article published on 31 October 2016

Development of a metabolically active, non-replicating sporozoite vaccine to prevent Plasmodium falciparum malaria

scientific article

Development of cultured Plasmodium falciparum blood-stage malaria cell banks for early phase in vivo clinical trial assessment of anti-malaria drugs and vaccines

scientific article

Development of two monoclonal antibodies against Plasmodium falciparum sporozoite surface protein 2 and mapping of B-cell epitopes ⬇️

scientific article published on August 1, 1997

Diagnosis of Resistance to Chloroquine by Plasmodium vivax: Timing of Recurrence and Whole Blood Chloroquine Levels ⬇️

scientific article published on June 1, 1997

Diagnosis, treatment, and prevention of malaria

scientific article

Differences in epitope recognition, isotype and titer of antisera to Plasmodium falciparum merozoite surface protein 4 raised by different modes of DNA or protein immunization

scientific article published in November 2000

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

scientific article

Discovery of Novel Plasmodium falciparum Pre-Erythrocytic Antigens for Vaccine Development

scientific article (publication date: 2015)

Duodenal string-capsule culture compared with bone-marrow, blood, and rectal-swab cultures for diagnosing typhoid and paratyphoid fever

scientific article

ELISPOT assay for detection of peptide specific interferon-gamma secreting cells in rhesus macaques

scientific article published in January 2001

Effect on antibody and T-cell responses of mixing five GMP-produced DNA plasmids and administration with plasmid expressing GM-CSF.

scientific article published in November 2004

Effective treatment and prevention of typhoid fever: updated

scientific article

Effects of lateral, medial, or complete septal lesions on response suppression ⬇️

scientific article published on April 1, 1979

Efficacy of murine malaria sporozoite vaccines: implications for human vaccine development

scientific article published in April 1987

Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

scientific article published on 31 May 2022

Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device

scientific article published in October 2001

Establishment of an in vitro assay for assessing the effects of drugs on the liver stages of Plasmodium vivax malaria

scientific article

Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection

scientific article

Evaluation of a DNA Probe for Identifying Salmonella typhi in Peruvian and Indonesian Bacterial Isolates ⬇️

scientific article published on May 1, 1988

Evaluation of vaccines designed to induce protective cellular immunity against the Plasmodium yoelii circumsporozoite protein: vaccinia, pseudorabies, and Salmonella transformed with circumsporozoite gene

scientific article published on January 1990

Experimental Challenge of Volunteers with Malaria

scientific article published on August 1, 1997

Expression of the chemokine MIG is a sensitive and predictive marker for antigen-specific, genetically restricted IFN-gamma production and IFN-gamma-secreting cells

scientific article published in November 2001

From genomics to vaccines: malaria as a model system

scientific article

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

scientific article

Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii

scientific article

Genome sequence of the human malaria parasite Plasmodium falciparum

scientific article

HIV treatments reduce malaria liver stage burden in a non-human primate model of malaria infection at clinically relevant concentrations in vivo

scientific article

HLA-A2-restricted cytotoxic T lymphocyte responses to multiple Plasmodium falciparum sporozoite surface protein 2 epitopes in sporozoite-immunized volunteers.

scientific article published on July 1995

HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles

scientific article

Haemoglobin dynamics in Papuan and non-Papuan adults in northeast Papua, Indonesia, with acute, uncomplicated vivax or falciparum malaria

scientific article

Halofantrine and primaquine for radical cure of malaria in Irian Jaya, Indonesia

scientific article published on January 1997

Hark back: passive immunotherapy for influenza and other serious infections.

scientific article

High-dose dexamethasone in quinine-treated patients with cerebral malaria: a double-blind, placebo-controlled trial

scientific article

High-throughput generation of P. falciparum functional molecules by recombinational cloning

scientific article published on October 2004

History of malaria in the United States Naval Forces at war: World War I through the Vietnam conflict

scientific article

Human cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein

scientific article published on April 1991

Human lymphocyte proliferative response to a sporozoite T cell epitope correlates with resistance to falciparum malaria.

scientific article

Humoral immune response to tetanus-diphtheria vaccine given during extended use of chloroquine or primaquine malaria chemoprophylaxis

scientific article

Humoral immune responses against Plasmodium vivax MSP1 in humans living in a malaria endemic area in Flores, Indonesia

scientific article

Humoral immune responses in volunteers immunized with irradiated Plasmodium falciparum sporozoites

scientific article published in August 1993

Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice

scientific article published on 9 October 2017

IFN-gamma inhibits development of Plasmodium berghei exoerythrocytic stages in hepatocytes by an L-arginine-dependent effector mechanism.

scientific article

IL-12 and NK cells are required for antigen-specific adaptive immunity against malaria initiated by CD8+ T cells in the Plasmodium yoelii model

scientific article

Identification and characterization of the protective hepatocyte erythrocyte protein 17 kDa gene of Plasmodium yoelii, homolog of Plasmodium falciparum exported protein 1.

scientific article published in July 1996

Identification of Plasmodium falciparum antigens by antigenic analysis of genomic and proteomic data

scientific article

Identification of a nonameric H-2Kk-restricted CD8+ cytotoxic T lymphocyte epitope on the Plasmodium falciparum circumsporozoite protein

scientific article

Idiopathic acute myocarditis during treatment for controlled human malaria infection: a case report

scientific article published on 30 January 2014

Immune response against the exp-1 protein of Plasmodium falciparum results in antibodies that cross-react with human T-cell lymphotropic virus type 1 proteins

scientific article

Immune response gene regulation of immunity to Plasmodium berghei sporozoites and circumsporozoite protein vaccines. Overcoming genetic restriction with whole organism and subunit vaccines.

scientific article published in May 1989

Immune response of humans to the circumsporozoite protein of Plasmodium falciparum: limited T cell response to the immunodominant central repeat region.

scientific article published in September 1988

Immune response to a hepatitis B DNA vaccine in Aotus monkeys: a comparison of vaccine formulation, route, and method of administration

scientific article

Immune responses and protection of Aotus monkeys immunized with irradiated Plasmodium vivax sporozoites

scientific article

Immunity to malaria and naturally acquired antibodies to the circumsporozoite protein of Plasmodium falciparum

scientific article

Immunization of malaria pre-exposed volunteers with PfSPZ Vaccine elicits long-lived IgM invasion-inhibitory and complement-fixing antibodies

scientific article published on 8 February 2018

Immunogenicity of Plasmodium falciparum circumsporozoite protein multiple antigen peptide vaccine formulated with different adjuvants.

scientific article published in January 1998

Immunological responses of neonates and infants to DNA vaccines

scientific article published on January 2006

Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

scientific article published on 18 December 2017

Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection

scientific article

Impact of transmission intensity and age on Plasmodium falciparum density and associated fever: implications for malaria vaccine trial design

scientific article published on October 1995

Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus

scientific article

In vitro expression and in vivo immunogenicity of Plasmodium falciparum pre-erythrocytic stage DNA vaccines

scientific article

In vitro growth inhibition of Plasmodium falciparum by sera from tropical splenomegaly syndrome patients.

scientific article

In vitro survival and retention of infectivity of Plasmodium yoelii sporozoites over extended periods of time.

scientific article published in October 1994

Inability of Malaria Vaccine to Induce Antibodies to a Protective Epitope Within Its Sequence ⬇️

scientific article published on February 8, 1991

Incidence of symptomatic and asymptomatic plasmodium falciparum infection following curative therapy in adult residents of northern Ghana

scientific article

Increased sample volume and use of quantitative reverse-transcription PCR can improve prediction of liver-to-blood inoculum size in controlled human malaria infection studies

scientific article

Inducing protective immune responses against the sporozoite and liver stages of Plasmodium

scientific article published on July 1994

Induction in humans of CD8+ and CD4+ T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein

scientific article published in May 2004

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine

scientific article

Induction of cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein by immunization with soluble recombinant protein without adjuvant

scientific article

Induction of murine cytotoxic T lymphocytes against Plasmodium falciparum sporozoite surface protein 2.

scientific article published in July 1994

Induction of protective CTL responses against the Plasmodium yoelii circumsporozoite protein by immunization with peptides.

scientific article published in October 1997

Induction of protective polyclonal antibodies by immunization with a Plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine

scientific article published in March 1995

Infectious disease. Research (genomics) is crucial to attacking malaria

scientific article

Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite

scientific article published on 05 July 2016

Interleukin 12 induction of interferon gamma-dependent protection against malaria

scientific article published in October 1994

Intestinal Parasites in Indochinese Immigrants *

scientific article published on March 1, 1981

Irradiated sporozoite vaccine induces HLA-B8-restricted cytotoxic T lymphocyte responses against two overlapping epitopes of the Plasmodium falciparum sporozoite surface protein 2 ⬇️

scientific article published on November 1, 1995

Irradiated sporozoite vaccine induces cytotoxic T lymphocytes that recognize malaria antigens on the surface of infected hepatocytes

scientific article published on August 1990

Knockout of Anopheles stephensi immune gene LRIM1 by CRISPR-Cas9 reveals its unexpected role in reproduction and vector competence

scientific article published on 16 November 2021

Laser capture microdissection and molecular analysis of Plasmodium yoelii liver-stage parasites

scientific article

Lessons learnt from the first controlled human malaria infection study conducted in Nairobi, Kenya

scientific article published on 28 April 2015

Long-term persistence of sterile immunity in a volunteer immunized with X-irradiated Plasmodium falciparum sporozoites

scientific article published in October 1993

Low immunogenicity of a Plasmodium vivax circumsporozoite protein epitope bound by a protective monoclonal antibody

scientific article published on December 1, 1992

Lymphocyte proliferative response and subset profiles during extended periods of chloroquine or primaquine prophylaxis

scientific article

Lymphocyte response to tetanus toxin T-cell epitopes: effects of tetanus vaccination and concurrent malaria prophylaxis

scientific article

Lymphocyte response to tetanus toxoid among Indonesian men immunized with tetanus-diphtheria during extended chloroquine or primaquine prophylaxis

scientific article published on December 1997

Lysis of human monocytic leukemia cells by extracellular adenosine triphosphate: mechanism and characterization of the adenosine triphosphate receptor.

scientific article published on September 1993

Malaria (part 1). Lessons from Somalia and General Slim.

scientific article published in March 1994

Malaria field studies at NAMRU-2, Indonesia

scientific article published on March 1993

Malaria in a nonimmune population after extended chloroquine or primaquine prophylaxis

scientific article published on February 1997

Malaria sporozoites and circumsporozoite protein bind sulfated glycans: carbohydrate binding properties predicted from sequence homologies with other lectins.

scientific article published on July 1993

Malaria sporozoites and circumsporozoite proteins bind specifically to sulfated glycoconjugates ⬇️

scientific article published on June 1, 1992

Malaria transmission dynamics at a site in northern Ghana proposed for testing malaria vaccines

scientific article published in January 2004

Malaria transmitted to humans by mosquitoes infected from cultured plasmodium falciparum

scientific article published in January 1986

Malaria vaccine development

scientific article published on July 1994

Malaria vaccine study site in Irian Jaya, Indonesia: Plasmodium falciparum incidence measurements and epidemiologic considerations in sample size estimation.

scientific article published on February 1994

Malaria vaccines-targeting infected hepatocytes

scientific article published in November 2000

Malaria: a protective paradox

scientific article published in December 2006

Malarial epitopes expressed on the surface of recombinant tobacco mosaic virus

scientific article published in January 1995

Mefloquine treatment for uncomplicated falciparum malaria in young children 6-24 months of age in northern Ghana.

scientific article published in February 2007

Meta-analysis: convalescent blood products for Spanish influenza pneumonia: a future H5N1 treatment?

scientific article

Microbial disease in humans: A genomic perspective

scientific article

Molecular dissection of the human antibody response to the structural repeat epitope of Plasmodium falciparum sporozoite from a protected donor

scientific article

Monoclonal antibodies of three different immunoglobulin G isotypes produced by immunization with a synthetic peptide or native protein protect mice against challenge with Plasmodium yoelii sporozoites ⬇️

scientific article

Monoclonal, but not polyclonal, antibodies protect against Plasmodium yoelii sporozoites.

scientific article published in February 1991

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

scientific article

Mosquito bite immunization with radiation-attenuated Plasmodium falciparum sporozoites: safety, tolerability, protective efficacy and humoral immunogenicity

scientific article published on 22 July 2016

Multi-gene vaccination against malaria: A multistage, multi-immune response approach

scientific article published in May 1997

Mutating the anchor residues associated with MHC binding inhibits and deviates CD8+ T cell mediated protective immunity against malaria

scientific article published on 12 December 2006

NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections

scientific article published on 27 November 2012

Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications

scientific article published in August 1987

Nucleic acid malaria vaccines. Current status and potential

scientific article published on November 1995

Nucleic acid vaccines against malaria

scientific article

Opposing effects of filariasis and chronic malaria on immunoregulatory T lymphocytes

scientific article published on January 1983

Optimising Controlled Human Malaria Infection Studies Using Cryopreserved P. falciparum Parasites Administered by Needle and Syringe

scientific article

Optimizing Intradermal Administration of Cryopreserved Plasmodium falciparum Sporozoites in Controlled Human Malaria Infection

scientific article

Pan DR binding sequence provides T-cell help for induction of protective antibodies against Plasmodium yoelii sporozoites

scientific article

Parasitology. Malaria--from infants to genomics to vaccines

scientific article published in July 2002

Partial protection against malaria by immunization with Leishmania enriettii expressing the Plasmodium yoelii circumsporozoite protein

scientific article published in February 1995

Persistence of protective immunity to malaria induced by DNA priming and poxvirus boosting: characterization of effector and memory CD8(+)-T-cell populations

scientific article

PfSPATR, a Plasmodium falciparum Protein Containing an Altered Thrombospondin Type I Repeat Domain Is Expressed at Several Stages of the Parasite Life Cycle and Is the Target of Inhibitory Antibodies ⬇️

scientific article (publication date: 11 July 2003)

Plague in the United States: the "black death" is still alive

scientific article

Plasmid DNA malaria vaccine: the potential for genomic integration after intramuscular injection

scientific article

Plasmid DNA malaria vaccine: tissue distribution and safety studies in mice and rabbits

scientific article

Plasmid vaccine expressing granulocyte-macrophage colony-stimulating factor attracts infiltrates including immature dendritic cells into injected muscles

scientific article published in October 2000

Plasmodium 18S rRNA of intravenously administered sporozoites does not persist in peripheral blood

scholarly article published by Stephen L Hoffman in 2018

Plasmodium falciparum Infection of Human Volunteers Activates Monocytes and CD16+ Dendritic Cells and Induces Upregulation of CD16 and CD1c Expression

scientific article

Plasmodium falciparum gametocytemia in Kenyan children: associations among age, intensity of exposure to transmission, and prevalence and density of subsequent gametocytemia

scientific article published in February 1997

Plasmodium falciparum malaria challenge by the bite of aseptic Anopheles stephensi mosquitoes: results of a randomized infectivity trial

scientific article (publication date: 21 October 2010)

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure

scientific article published on 23 August 2017

Plasmodium falciparum-infected Anopheles stephensi inconsistently transmit malaria to humans

scientific article published in November 1990

Plasmodium falciparum: exported protein-1, a blood stage antigen, is expressed in liver stage parasites

scientific article published in August 1994

Plasmodium falciparum: from genomic sequence to vaccines and drugs.

scientific article published in January 2000

Plasmodium falciparum: sporozoite boosting of immunity due to a T-cell epitope on a sporozoite vaccine

scientific article published in August 1987

Plasmodium liver load following parenteral sporozoite administration in rodents

scientific article published on 9 October 2012

Plasmodium vivax: freeze-fracture studies on the ultrastructure of the sporozoites within the salivary gland of the mosquito Anopheles stephensi

scientific article published in May 1995

Plasmodium yoelii-infected A. stephensi inefficiently transmit malaria compared to intravenous route

scientific article (publication date: 28 January 2010)

Plasmodium yoelii: 17-kDa hepatic and erythrocytic stage protein is the target of an inhibitory monoclonal antibody

scientific article published in May 1995

Plasmodium yoelii: cloning and characterization of the gene encoding for the mitochondrial heat shock protein 60.

scientific article published on December 1999

Plasmodium yoelii: expression of circumsporozoite protein and sporozoite surface protein 2 by sporozoites in culture

scientific article published in December 1995

Plasmodium, human and Anopheles genomics and malaria

scientific article

Plasmodium: mammalian codon optimization of malaria plasmid DNA vaccines enhances antibody responses but not T cell responses nor protective immunity

scientific article published on 26 February 2009

Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates

scientific article

Polymerase chain reaction amplification from Plasmodium falciparum on dried blood spots

scientific article published in April 1995

Potent immunogenic short linear peptide constructs composed of B cell epitopes and Pan DR T helper epitopes (PADRE) for antibody responses in vivo

scientific article published in March 1997

Pre-erythrocytic-stage immune effector mechanisms in Plasmodium spp. infections

scientific article

Predicting outcome in malaria: correlation between rate of exposure to infected mosquitoes and level of Plasmodium falciparum parasitemia.

scientific article published in November 1994

Presidential address: The American Society of Tropical Medicine and Hygiene in the last half century: from apparent anachronism to international leader and innovator.

scientific article published in July 2002

Prevention and treatment of vivax malaria

scientific article

Prevention of malaria in travelers

scientific article

Primaquine for prevention of malaria in travelers

scientific article

Primaquine therapy for malaria

scientific article

Production of monoclonal antibodies against a 19-kD recombinant Plasmodium vivax MSP1 for detection of P. vivax malaria in Turkey

scientific article published in April 2004

Progress toward malaria preerythrocytic vaccines

scientific article published on April 1991

Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines

scientific article published on 12 October 2015

Protection against Plasmodium falciparum malaria by PfSPZ Vaccine.

scientific article

Protection against inhalation anthrax by immunization with Salmonella enterica serovar Typhi Ty21a stably producing protective antigen of Bacillus anthracis

scientific article published on 15 June 2017

Protection against malaria at 1 year and immune correlates following PfSPZ vaccination

scientific article (publication date: 9 May 2016)

Protection against malaria by Plasmodium yoelii sporozoite surface protein 2 linear peptide induction of CD4+ T cell- and IFN-gamma-dependent elimination of infected hepatocytes

scientific article published in November 1996

Protection against malaria by immunization with a Plasmodium yoelii circumsporozoite protein nucleic acid vaccine

scientific article published in December 1994

Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine

scientific article

Protection against malaria by vaccination with sporozoite surface protein 2 plus CS protein ⬇️

scientific article published on May 3, 1991

Protection of Aotus monkeys by Plasmodium falciparum EBA-175 region II DNA prime-protein boost immunization regimen

scientific article published on 8 December 2000

Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites

scientific article (publication date: 15 April 2002)

Protection of rhesus macaques against lethal Plasmodium knowlesi malaria by a heterologous DNA priming and poxvirus boosting immunization regimen

scientific article

Protective efficacy against malaria of a combination sporozoite and erythrocytic stage vaccine

scientific article published in November 1996

Purnomo Projodipuro (April 11, 1934-May 10, 2013)

scientific article

Pyrimethamine-sulfadoxine still effective against Plasmodium falciparum in Jayapura, Irian Jaya: RI-type resistance in 2 of 18 patients

scientific article

Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue

scientific article published on 31 October 2011

Randomized, placebo-controlled trial of atovaquone/proguanil for the prevention of Plasmodium falciparum or Plasmodium vivax malaria among migrants to Papua, Indonesia

scientific article

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

scientific article published on 22 November 2017

Rationale and approaches to constructing preerythrocytic malaria vaccines.

scientific article published on January 1995

Rationale and plans for developing a non-replicating, metabolically active, radiation-attenuatedPlasmodium falciparumsporozoite vaccine ⬇️

scientific article published on November 1, 2003

Recombinant attenuated Toxoplasma gondii expressing the Plasmodium yoelii circumsporozoite protein provides highly effective priming for CD8+ T cell-dependent protective immunity against malaria

scientific article published on August 2000

Recombinant pseudorabies virus carrying a plasmodium gene: herpesvirus as a new live viral vector for inducing T- and B-cell immunity

scientific article published on January 1, 1992

Reduction of Mortality in Chloramphenicol-Treated Severe Typhoid Fever by High-Dose Dexamethasone ⬇️

scientific article published on January 12, 1984

Reduction of Suppressor T Lymphocytes in the Tropical Splenomegaly Syndrome ⬇️

scientific article published on February 9, 1984

Reduction of mortality in chloramphenicol-treated patients with severe typhoid fever by high dose dexamethasone

scientific article

Rehydration and maintenance therapy of cholera patients in Jakarta: citrate-based versus bicarbonate-based oral rehydration salt solution

scientific article published in December 1985

Research note: HLA degenerate T-cell epitopes from Plasmodium falciparum liver stage-specific antigen 1 (LSA-1) are highly conserved in isolates from geographically distinct areas

scientific article published in September 2000

Research toward vaccines against malaria

scientific article published on May 1998

Resistance to Chloroquine by Plasmodium vivax in Irian Jaya, Indonesia

scientific article published on May 1, 1991

Robust, reproducible, industrialized, standard membrane feeding assay for assessing the transmission blocking activity of vaccines and drugs against Plasmodium falciparum

scientific article published on 9 April 2015

Ruth Nussenzweig (1928-2018) Malaria Vaccine and Immunology Pioneer

scholarly article published by Stephen L Hoffman in 2018

Safety and clinical outcome of experimental challenge of human volunteers with Plasmodium falciparum-infected mosquitoes: an update

scientific article published on 29 May 2007

Safety and immunogenicity in volunteers of a recombinant Plasmodium falciparum circumsporozoite protein malaria vaccine produced in Lepidopteran cells

scientific article published on January 1, 1992

Safety of a GM-CSF adjuvant-plasmid DNA malaria vaccine

scientific article

Safety, Immunogenicity, and Protective Efficacy against Controlled Human Malaria Infection of Sporozoite Vaccine in Tanzanian Adults

scholarly article published by Tobias Schindler in 2018

Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial

scientific article published on 28 December 2015

Safety, immunogenicity, and efficacy of a malaria sporozoite vaccine administered with monophosphoryl lipid A, cell wall skeleton of mycobacteria, and squalane as adjuvant

scientific article published in November 1994

Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers

scientific article published in March 2000

Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A.

scientific article published in April 2004

Safety, tolerability, and lack of antibody responses after administration of a PfCSP DNA malaria vaccine via needle or needle-free jet injection, and comparison of intramuscular and combination intramuscular/intradermal routes

scientific article published in September 2002

Seasonal malaria attack rates in infants and young children in northern Ghana

scholarly article

Seasonal profiles of malaria infection, anaemia, and bednet use among age groups and communities in northern Ghana

scientific article published on September 2003

Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14

scientific article (publication date: 3 October 2002)

Sequence of the immunodominant epitope for the surface protein on sporozoites of Plasmodium vivax

scientific article

Sequencing the genome of Plasmodium falciparum

scientific article published on October 1998

Severe anemia in young children after high and low malaria transmission seasons in the Kassena-Nankana district of northern Ghana.

scientific article published in June 2000

Short report: therapeutic efficacy of chloroquine combined with primaquine against Plasmodium falciparum in northeastern Papua, Indonesia

scientific article published in June 2002

Splenectomy in massive tropical splenomegaly: two-to six-year follow-up in 14 patients

scientific article

Sporozoite vaccine induces genetically restricted T cell elimination of malaria from hepatocytes

scientific article

Sterile protection of monkeys against malaria after administration of interleukin-12.

scientific article published in January 1997

Strategy for development of a pre-erythrocytic Plasmodium falciparum DNA vaccine for human use ⬇️

scientific article published on June 1, 1997

Streptokinase clot culture compared with whole blood culture for isolation of Salmonella typhi and S. paratyphi A from patients with enteric fever

scientific article

Successful human infection with P. falciparum using three aseptic Anopheles stephensi mosquitoes: a new model for controlled human malaria infection

scientific article

Successful induction of CD8 T cell-dependent protection against malaria by sequential immunization with DNA and recombinant poxvirus of neonatal mice born to immune mothers

scientific article published in September 2003

Synthesis and immunological characterization of 104-mer and 102-mer peptides corresponding to the N- and C-terminal regions of the Plasmodium falciparum CS protein

scientific article published in December 1995

Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys

scientific article published in August 1999

T lymphocytes from mice immunized with irradiated sporozoites eliminate malaria from hepatocytes

scientific article published on January 1990

TDR thirty years on: taking stock and envisioning the future for the Special Programme for Research and Training in Tropical Diseases

scientific article

The Effects of radiation on the safety and protective efficacy of an attenuated Plasmodium yoelii sporozoite malaria vaccine

scientific article published on 9 December 2008

The Genome Sequence of the Malaria Mosquito Anopheles gambiae

scientific article

The Malaria Genome Sequencing Project ⬇️

scientific article published on May 5, 1998

The Widal slide agglutination test, a valuable rapid diagnostic test in typhoid fever patients at the Infectious Diseases Hospital of Jakarta

scientific article

The complexity of protective immunity against liver-stage malaria

scientific article published in August 2000

The development of a multivalent DNA vaccine for malaria

scientific article

The malaria genome sequencing project: complete sequence of Plasmodium falciparum chromosome 2.

scientific article

The march toward malaria vaccines

scientific article published on 28 August 2015

The micro in vitro test for malaria drug resistance in Irian Jaya: 28 and 48-hour incubation yield similar probit analysis findings

scientific article published in January 1985

The potential role of vaccines in the elimination of falciparum malaria and the eventual eradication of malaria

scientific article published in December 2009

The role of CD4+ T cells in immunity to malaria sporozoites

scientific article published in September 1993

Toward clinical trials of DNA vaccines against malaria

scientific article published on August 1997

Travel vaccines

scientific article

Treatment of chloroquine-resistant Plasmodium vivax with chloroquine and primaquine or halofantrine

scientific article published on June 1995

Treatment of severe typhoid fever in children with high dose dexamethasone.

scientific article

Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development

scientific article (publication date: May 2014)

Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes

scientific article (publication date: May 2014)

Use of a DNA probe to detect Salmonella typhi in the blood of patients with typhoid fever

scientific article published on May 1989

Use of synthetic and recombinant peptides in the study of host-parasite interactions in the malarias

scientific article published in November 1987

Utilization of genomic sequence information to develop malaria vaccines ⬇️

scientific article published on November 1, 2003

Whole blood transcriptome changes following controlled human malaria infection in malaria pre-exposed volunteers correlate with parasite prepatent period.

scientific article published on 19 June 2018

γδ T Cells Are Required for the Induction of Sterile Immunity during Irradiated Sporozoite Vaccinations.

scientific article published on 27 October 2017

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