List of works by Christopher J Hanley

A subset of myofibroblastic cancer-associated fibroblasts regulate collagen fiber elongation, which is prognostic in multiple cancers

scientific article published on 23 December 2015

An optimised tissue disaggregation and data processing pipeline for characterising fibroblast phenotypes using single-cell RNA sequencing

scientific article published on 03 July 2019

CTEN Induces Tumour Cell Invasion and Survival and Is Prognostic in Radiotherapy-Treated Head and Neck Cancer

scientific article published on 13 October 2020

Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis

scientific article published on 15 December 2016

Intratumoral follicular regulatory T cells curtail anti-PD-1 treatment efficacy

scientific article published on 24 June 2021

NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors

scientific article published on 02 March 2020

PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells

scientific article published on 01 July 2018

Pro-migratory and TGF-β-activating functions of αvβ6 integrin in pancreatic cancer are differentially regulated via an Eps8-dependent GTPase switch.

scientific article published on 13 June 2017

Single-cell transcriptomic analysis of tissue-resident memory T cells in human lung cancer

scientific article published on 21 June 2019

Targeting the Myofibroblastic Cancer-Associated Fibroblast Phenotype Through Inhibition of NOX4.

scientific article

Transglutaminase-2 Mediates the Biomechanical Properties of the Colorectal Cancer Tissue Microenvironment that Contribute to Disease Progression

scientific article published on 21 May 2019

Tumor resident stromal cells promote breast cancer invasion through regulation of the basal phenotype

scientific article published on 31 August 2020

mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

scientific article