List of works - Jerome de Ruyck

Computational characterization of the binding mode between oncoprotein Ets-1 and DNA-repair enzymes

scientific article published on 25 September 2018

Determination of Kinetics and the Crystal Structure of a Novel Type 2 Isopentenyl Diphosphate: Dimethylallyl Diphosphate Isomerase from Streptococcus pneumoniae

scientific article

How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.

scientific article published on 14 July 2015

Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis: Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes.

scientific article published on July 2011

Molecular docking as a popular tool in drug design, an in silico travel

scientific article

Monoclinic form of isopentenyl diphosphate isomerase: a case of polymorphism in biomolecular crystals

scientific article

Overexpression, physicochemical characterization, and modeling of a hyperthermophilic pyrococcus furiosus type 2 IPP isomerase.

scientific article published in June 2008

Physiochemical Tuning of Potent Escherichia coli Anti-Adhesives by Microencapsulation and Methylene Homologation

scientific article published on 3 March 2017

Signal Transduction by BvgS Sensor Kinase: BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY.

scientific article published on 22 July 2015

Signal transduction by BvgS sensor kinase. Binding of modulator nicotinate affects the conformation and dynamics of the entire periplasmic moiety

scientific article published in October 2015

Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography

scientific article published on 15 April 2006

Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics.

scientific article published on 27 October 2005

Structure-Based Design and Synthesis of Piperidinol-Containing Molecules as New Mycobacterium abscessus Inhibitors

scientific article published on 20 March 2020

Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes.

scientific article published on April 2008

Structures of C-mannosylated anti-adhesives bound to the type 1 fimbrial FimH adhesin

scientific article

TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells

scientific article published on 30 April 2022

Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation-The Example of FimH

scientific article published on 05 July 2018

Tetartohedral twinning in IDI-2 from Thermus thermophilus: crystallization under anaerobic conditions.

scientific article published on 19 February 2014

The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut

scientific article

List of works by Jerome de Ruyck

Computational characterization of the binding mode between oncoprotein Ets-1 and DNA-repair enzymes

Determination of Kinetics and the Crystal Structure of a Novel Type 2 Isopentenyl Diphosphate: Dimethylallyl Diphosphate Isomerase from Streptococcus pneumoniae

How does binding of imidazole-based inhibitors to heme oxygenase-1 influence their conformation? Insights combining crystal structures and molecular modelling.

Inhibition Studies on Enzymes Involved in Isoprenoid Biosynthesis: Focus on Two Potential Drug Targets: DXR and IDI-2 Enzymes.

Molecular docking as a popular tool in drug design, an in silico travel

Monoclinic form of isopentenyl diphosphate isomerase: a case of polymorphism in biomolecular crystals

Overexpression, physicochemical characterization, and modeling of a hyperthermophilic pyrococcus furiosus type 2 IPP isomerase.

Physiochemical Tuning of Potent Escherichia coli Anti-Adhesives by Microencapsulation and Methylene Homologation

Signal Transduction by BvgS Sensor Kinase: BINDING OF MODULATOR NICOTINATE AFFECTS THE CONFORMATION AND DYNAMICS OF THE ENTIRE PERIPLASMIC MOIETY.

Signal transduction by BvgS sensor kinase. Binding of modulator nicotinate affects the conformation and dynamics of the entire periplasmic moiety

Structural role for Tyr-104 in Escherichia coli isopentenyl-diphosphate isomerase: site-directed mutagenesis, enzymology, and protein crystallography

Structure of Thermus thermophilus type 2 isopentenyl diphosphate isomerase inferred from crystallography and molecular dynamics.

Structure-Based Design and Synthesis of Piperidinol-Containing Molecules as New Mycobacterium abscessus Inhibitors

Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes.

Structures of C-mannosylated anti-adhesives bound to the type 1 fimbrial FimH adhesin

TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells

Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation-The Example of FimH

Tetartohedral twinning in IDI-2 from Thermus thermophilus: crystallization under anaerobic conditions.

The Antiadhesive Strategy in Crohn's Disease: Orally Active Mannosides to Decolonize Pathogenic Escherichia coli from the Gut