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List of works by Ayman Al-Hendy

1,25 Dihydroxyvitamin D3 Enhances the Antifibroid Effects of Ulipristal Acetate in Human Uterine Fibroids

1,25-Dihydroxyvitamin D deficiency is associated with preterm birth in African American and Caucasian women

scientific article published on 21 June 2013

1,25-Dihydroxyvitamin D3 Reduces TGF-β3-Induced Fibrosis-Related Gene Expression in Human Uterine Leiomyoma Cells ⬇️

scientific article published on February 2, 2011

1,25-dihydroxyvitamin D3 regulates expression of sex steroid receptors in human uterine fibroid cells

scientific article

1,25-dihydroxyvitamin D3 treatment shrinks uterine leiomyoma tumors in the Eker rat model

scientific article

1,25-dihydroxyvitamin d3 reduces extracellular matrix-associated protein expression in human uterine fibroid cells

scientific article

2-Methoxyestradiol and multidrug resistance: can 2-methoxyestradiol chemosensitize resistant breast cancer cells?

scientific article published on 29 January 2008

2-Methoxyestradiol reverses doxorubicin resistance in human breast tumor xenograft.

scientific article published on 6 February 2008

A Preliminary Study: Human Fibroid Stro-1+/CD44+ Stem Cells Isolated From Uterine Fibroids Demonstrate Decreased DNA Repair and Genomic Integrity Compared to Adjacent Myometrial Stro-1+/CD44+ Cells

scientific article published on 28 June 2018

A single-nucleotide polymorphism in the fetal catechol-O-methyltransferase gene is associated with spontaneous preterm birth in African Americans

scientific article

Abrogation of estrogen receptor signaling augments cytotoxicity of anticancer drugs on CaSki cervical cancer cells.

scientific article published on July 2008

Activation of β-Catenin Signaling and its Crosstalk With Estrogen and Histone Deacetylases in Human Uterine Fibroids

scientific article published on 01 April 2020

Adenovirus-mediated delivery of a dominant-negative estrogen receptor gene in uterine leiomyoma cells abrogates estrogen- and progesterone-regulated gene expression

scientific article

Adenovirus-mediated expression of cyclooxygenase-2 antisense reverse abnormal genetic profile of human adhesion fibroblasts

scientific article published on 10 July 2007

Adenovirus-mediated overexpression of human tissue plasminogen activator prevents peritoneal adhesion formation/reformation in rats.

scientific article published in July 2009

Adipocytes Enhance the Proliferation of Human Leiomyoma Cells Via TNF-α Proinflammatory Cytokine ⬇️

scientific article published on December 1, 2011

Alcohol Consumption and Risk of Uterine Fibroids

scientific article published on 01 January 2020

Altered expression of histone deacetylases, inflammatory cytokines and contractile-associated factors in uterine myometrium of Long Evans rats gestationally exposed to benzo[a]pyrene

scientific article

An Open Letter to the Food and Drug Administration Regarding the Use of Morcellation Procedures in Women Having Surgery for Presumed Uterine Myomas

scientific article

Antiproliferative and proapoptotic effects of epigallocatechin gallate on human leiomyoma cells

scientific article

Atypical Presentations of Molar Pregnancy: Diagnostic Roles of Imaging, β-Human Chorionic Gonadotropin Measurement, and p57 Immunostaining.

scientific article

Berberine Inhibits Uterine Leiomyoma Cell Proliferation via Downregulation of Cyclooxygenase 2 and Pituitary Tumor-Transforming Gene 1.

scientific article published on 30 October 2016

Berberine inhibits the proliferation of human uterine leiomyoma cells

scientific article published on 14 February 2015

Biomarkers of endometriosis

scientific article published in July 2008

Bone Marrow Transplantation Restores Follicular Maturation and Steroid Hormones Production in a Mouse Model for Primary Ovarian Failure ⬇️

scientific article published on March 7, 2012

Burden, Prevalence, and Treatment of Uterine Fibroids: A Survey of U.S. Women

Can vitamin D reduce the risk of uterine fibroids?

scientific article

Cardiac Surgery and the Blood-Brain Barrier

scientific article published on 09 October 2019

Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups

scientific article published on February 2006

Catecholestrogens induce oxidative stress and malignant transformation in human endometrial glandular cells: protective effect of catechol-O-methyltransferase.

scientific article

Cervical superficial myofibroblastoma: Case report and review of the literature

scientific article published on 4 September 2017

Circulating Micro-RNAs as Diagnostic Biomarkers for Endometriosis: Privation and Promise

scientific article

Converting of Myometrial Stem Cells to Tumor-Initiating Cells: Mechanism of Uterine Fibroid Development

scientific article published on 30 April 2016

Defective expression of ATG4D abrogates autophagy and promotes growth in human uterine fibroids

scientific article

Detecting Changes in the Cervix with Raman Spectroscopy

Detecting biochemical changes in the rodent cervix during pregnancy using Raman spectroscopy

scientific article published on 13 March 2012

Detecting changes during pregnancy with Raman spectroscopy

Detecting changes during pregnancy with Raman spectroscopy

Developmental Environmental Exposure Alters the Epigenetic Features of Myometrial Stem Cells

scientific article

Developmental Exposure to Endocrine Disruptors Expands Murine Myometrial Stem Cell Compartment as a Prerequisite to Leiomyoma Tumorigenesis

scientific article published on 14 October 2016

Developmental exposure to endocrine disrupting chemicals alters the epigenome: Identification of reprogrammed targets

scientific article published on 03 May 2016

Diet-induced vitamin D deficiency triggers inflammation and DNA damage profile in murine myometrium

Early Life Adverse Environmental Exposures Increase the Risk of Uterine Fibroid Development: Role of Epigenetic Regulation

scientific article

Elagolix Alone or With Add-Back Therapy in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas: A Randomized Controlled Trial

scientific article published on 01 November 2018

Elagolix Treatment for Up to 12 Months in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas

scientific article published on 01 June 2020

Elagolix for Heavy Menstrual Bleeding in Women with Uterine Fibroids

scientific article published on 01 January 2020

Elevated expression of catechol-O-methyltransferase is associated with labor and increased prostaglandin E(2) production by human fetal membranes

scientific article published on 07 August 2009

Endocrine disruptor exposure during development increases incidence of uterine fibroids by altering DNA repair in myometrial stem cells

article

Endocrine-disrupting chemicals and uterine fibroids

scientific article published on 20 August 2016

Enhancing Adenoviral-Mediated Gene Transfer and Expression to Endometrial Cells

scientific article

Environmental risk factors for prevention and molecular intervention of cervical cancer

scientific article published on 8 December 2006

Estrogen Receptors and Signaling in Fibroids: Role in Pathobiology and Therapeutic Implications.

scientific article published on 20 November 2016

Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: a potential medicinal treatment for uterine fibroids

scientific article

Ethnic distribution of estrogen receptor-alpha polymorphism is associated with a higher prevalence of uterine leiomyomas in black Americans

scientific article published on 24 July 2006

Evolving role of microRNAs in uterine fibroid pathogenesis: filling the gap!

scientific article published on 01 June 2020

Expanding upon the Human Myometrial Stem Cell Hypothesis and the Role of Race, Hormones, Age, and Parity in a Profibroid Environment

Expression and cyclic variations of catechol-O-methyl transferase in human endometrial stroma

scientific article

Expression of stem and germ cell markers within nonfollicle structures in adult mouse ovary

scientific article published on 18 December 2007

FSH receptor (FSHR) expression in human extragonadal reproductive tissues and the developing placenta, and the impact of its deletion on pregnancy in mice.

scientific article published on 6 August 2014

Gene therapy and uterine leiomyoma: a review

scientific article

Gene therapy of benign gynecological diseases

scientific article published on 13 May 2009

Gene therapy of uterine leiomyomas: adenovirus-mediated expression of dominant negative estrogen receptor inhibits tumor growth in nude mice

scientific article

Gene therapy targeting leiomyoma: adenovirus-mediated delivery of dominant-negative estrogen receptor gene shrinks uterine tumors in Eker rat model

scientific article

Green tea extract inhibition of human leiomyoma cell proliferation is mediated via catechol-O-methyltransferase

scientific article

Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice

scientific article

Gynecologic disorders and menstrual cycle lightheadedness in postural tachycardia syndrome ⬇️

scientific article published on June 20, 2012

H19 lncRNA identified as a master regulator of genes that drive uterine leiomyomas

scientific article published on 15 May 2019

Hormonal regulation of catechol-O-methyl transferase activity in women with uterine leiomyomas

scientific article published in July 2006

Human Mesenchymal Stem Cells Partially Reverse Infertility in Chemotherapy-Induced Ovarian Failure

scientific article published on January 2017

Hypovitaminosis D and high serum transforming growth factor beta-3: important biomarkers for uterine fibroids risk

scientific article published on 25 October 2016

Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment

scientific article published on 26 November 2018

Identification and potential role of telocytes in human uterine leiomyoma.

scientific article

Identification of Polycomb Group Protein EZH2-Mediated DNA Mismatch Repair Gene MSH2 in Human Uterine Fibroids

scientific article published on 31 March 2016

Increased COMT expression in PCOS biology

scientific article published on 10 February 2012

Inhibition of growth of cervical cancer cells using a dominant negative estrogen receptor gene

scientific article published on 29 November 2006

Innovative Oral Treatments of Uterine Leiomyoma ⬇️

scientific article published on February 16, 2012

Intraovarian injection of autologous human mesenchymal stem cells increases estrogen production and reduces menopausal symptoms in women with premature ovarian failure: two case reports and a review of the literature

scientific article published on 18 July 2020

Intravenous Infusion of Nucleated Peripheral Blood Cells Restores Fertility in Mice with Chemotherapy-Induced Premature Ovarian Failure

article by Abdeljabar El Andaloussi et al published 15 September 2018 in Biomedicines

Introduction of Somatic Mutation in MED12 Induces Wnt4/β-Catenin and Disrupts Autophagy in Human Uterine Myometrial Cell

scientific article published on 06 January 2020

Krukenberg tumor presenting as back pain and a positive urine pregnancy test: a case report and literature review

scientific article

Laparoscopic management of a large torted ovarian cyst in an adolescent virgin: a case report ⬇️

scientific article published on May 15, 2012

Low-dose simultaneous delivery of adenovirus encoding hepatocyte growth factor and vascular endothelial growth factor in dogs enhances liver proliferation without systemic growth factor elevation.

scientific article

Lower levels of urinary 2-hydroxyestrogens in polycystic ovary syndrome

scientific article published on 29 May 2007

Mediator Kinase Disruption in MED12-Mutant Uterine Fibroids From Hispanic Women of South Texas

scientific article published on 01 November 2018

Memy I: a novel murine model for uterine leiomyoma using adenovirus-enhanced human fibroid explants in severe combined immune deficiency mice

scientific article

Mesenchymal Stem Cells as a Bio Organ for Treatment of Female Infertility

scientific article published on 08 October 2020

Molecular Bio-Imaging Probe for Non-Invasive Differentiation Between Human Leiomyoma Versus Leiomyosarcoma

scientific article published on 10 January 2020

Molecular genetics and racial disparities of uterine leiomyomas

scientific article

Multiplexed quantitation of endogenous estrogens and estrogen metabolites in human peritoneal fluid

scientific article

Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression

scientific article

Myometrial progesterone hyper-responsiveness associated with increased risk of human uterine fibroids

scientific article published on 09 July 2019

Neurotrimin: a novel neural cell adhesion molecule correlating with uterine fibroid phenotype

scientific article published on 01 January 2020

Nicotinamide adenine dinucleotide phosphate oxidase is differentially regulated in normal myometrium versus leiomyoma

scientific article published on 11 February 2014

Non-coding RNAs: an important regulatory mechanism in pathogenesis of uterine fibroids

scientific article published on 01 May 2018

Non-hormonal mediators of uterine fibroid growth

scientific article published on 27 July 2020

Novel MED12 gene somatic mutations in women from the Southern United States with symptomatic uterine fibroids.

scientific article

Novel effects of simvastatin on uterine fibroid tumors: in vitro and patient-derived xenograft mouse model study

scientific article published on 31 March 2015

Obesity and the Endometrium: Adipocyte-Secreted Proinflammatory TNF α Cytokine Enhances the Proliferation of Human Endometrial Glandular Cells

scientific article published on 30 October 2013

Oncogenic exon 2 mutations in Mediator subunit MED12 disrupt allosteric activation of Cyclin C-CDK8/19.

scientific article published on 13 February 2018

Opinions and Practice of US-Based Obstetrician-Gynecologists regarding Vitamin D Screening and Supplementation of Pregnant Women

scientific article published on 25 August 2016

Origin of Uterine Fibroids: Conversion of Myometrial Stem Cells to Tumor-Initiating Cells

scientific article published on 3 November 2017

Oxidative stress: a key regulator of leiomyoma cell survival

scientific article published on 5 May 2017

PDL-1 blockade prevents T cell exhaustion, inhibits autophagy, and promotes clearance of Leishmania donovani.

scientific article

Paricalcitol, a vitamin d receptor activator, inhibits tumor formation in a murine model of uterine fibroids

scientific article

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry

scientific article published on 23 December 2021

Potential nonhormonal therapeutics for medical treatment of leiomyomas

scientific article published on May 2004

Predictors of Response for Elagolix with Add-back Therapy in Women with Heavy Menstrual Bleeding Associated with Uterine Fibroids

scientific article published on 20 July 2020

Progesterone regulates catechol-O-methyl transferase gene expression in breast cancer cells: distinct effect of progesterone receptor isoforms

scientific article

Progesterone-mediated regulation of catechol-O-methyl transferase expression in endometrial cancer cells

scientific article

Protective cardiovascular and renal actions of vitamin D and estrogen ⬇️

scientific article published on January 1, 2013

Proteogenomic landscape of uterine leiomyomas from hereditary leiomyomatosis and renal cell cancer patients

scientific article published on 30 April 2021

Racial and ethnic differences in the pathogenesis and clinical manifestations of uterine leiomyoma

scientific article

Regulation of catechol O-methyltransferase expression in granulosa cells: a potential role for follicular arrest in polycystic ovary syndrome

scientific article

Regulation of catechol-O-methyltransferase expression in human myometrial cells

scientific article

Report of Exosomes Isolated from a Human Uterine Leiomyoma Cell Line and Their Impact on Endometrial Vascular Endothelial Cells

scientific article published on 05 May 2022

Role of Stro1+/CD44+ stem cells in myometrial physiology and uterine remodeling during pregnancy

scientific article published on January 2017

Role of vitamin D in uterine fibroid biology

scientific article

SUN-019 The Selective Progesterone Receptor Modulator Ulipristal Acetate Blocks Glucocorticoid Receptor Transactivation

Selective progesterone receptor modulators for fertility preservation in women with symptomatic uterine fibroids

scientific article published on 28 August 2017

Sertoli-Leydig cell tumor with unique nail findings in a post-menopausal woman: a case report and literature review.

scientific article

Serum cytokines as biomarkers for nonsurgical prediction of endometriosis

scientific article published on 19 June 2007

Serum vitamin D3 level inversely correlates with uterine fibroid volume in different ethnic groups: a cross-sectional observational study

scientific article

Signaling Pathways in Leiomyoma: Understanding Pathobiology and Implications for Therapy

scientific article published on 13 April 2015

Silencing Med12 Gene Reduces Proliferation of Human Leiomyoma Cells Mediated via Wnt/β-Catenin Signaling Pathway

scientific article published on 14 December 2016

Simvastatin and uterine fibroids: opportunity for a novel therapeutic option

scientific article published on 01 December 2018

Simvastatin inhibits stem cell proliferation in human leiomyoma via TGF-β3 and Wnt/β-Catenin pathways

scientific article published on 04 February 2022

Simvastatin potently induces calcium-dependent apoptosis of human leiomyoma cells

scientific article

Soluble tumor necrosis factor-alpha receptors in the serum of endometriosis patients

scientific article

Stro-1/CD44 as putative human myometrial and fibroid stem cell markers.

scientific article published on 16 May 2015

Successes and failures of uterine leiomyoma drug discovery

scientific article published on 18 December 2017

Targeted Adenoviral Vector Demonstrates Enhanced Efficacy for In Vivo Gene Therapy of Uterine Leiomyoma

scientific article published on 16 February 2016

Targeting Hedgehog Pathway and DNA Methyltransferases in Uterine Leiomyosarcoma Cells

scientific article published on 31 December 2020

Targeting the transforming growth factor-β pathway: a novel mechanism of ulipristal acetate action against uterine fibroids

scientific article published on 01 April 2019

The Emerging Role of p27 in Development of Diseases

scientific article published on 09 May 2018

The Emerging Spectrum of Early Life Exposure-Related Inflammation and Epigenetic Therapy

scientific article published on 17 September 2018

The Evolving Role of Natural Compounds in the Medical Treatment of Uterine Fibroids

scientific article published on 14 May 2020

The Mechanism and Function of Epigenetics in Uterine Leiomyoma Development

scientific article published on 28 April 2015

The Polycomb Group Protein EZH2 Impairs DNA Damage Repair Gene Expression in Human Uterine Fibroids

scientific article published on 17 February 2016

The Role of Gene Therapy in Premature Ovarian Insufficiency Management

article

The Role of Hedgehog Pathway in Female Cancers

scientific article published on 09 October 2020

The Selective Progesterone Receptor Modulator Ulipristal Acetate Inhibits the Activity of the Glucocorticoid Receptor

scientific article published on 01 March 2020

The Significance of Measuring Vitamin D Serum Levels in Women with Uterine Fibroids

scientific article published on 27 October 2020

The effect of over-expression of sFlt-1 on blood pressure and the occurrence of other manifestations of preeclampsia in unrestrained conscious pregnant mice

scientific article published on 01 April 2007

The emerging role of extracellular vesicle-derived miRNAs: implication in cancer progression and stem cell related diseases

scientific article published on 31 January 2016

The ontogeny of myometrial stem cells in OCT4-GFP transgenic mouse model

scholarly article by Soumia Brakta et al published 29 November 2018 in Stem Cell Research & Therapy

The role of endocrine-disrupting chemicals in uterine fibroid pathogenesis

scientific article published on 09 October 2020

Toward gene therapy of endometriosis: adenovirus-mediated delivery of dominant negative estrogen receptor genes inhibits cell proliferation, reduces cytokine production, and induces apoptosis of endometriotic cells

scientific article published on 7 March 2007

Toward gene therapy of endometriosis: transductional and transcriptional targeting of adenoviral vectors to endometriosis cells

scientific article

Towards Cell free Therapy of Premature Ovarian Insufficiency: Human Bone Marrow Mesenchymal Stem Cells Secretome Enhances Angiogenesis in Human Ovarian Microvascular Endothelial Cells

scientific article published on 06 November 2019

Towards fibroid gene therapy: adenovirus-mediated delivery of herpes simplex virus 1 thymidine kinase gene/ganciclovir shrinks uterine leiomyoma in the Eker rat model

scientific article

Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study

scientific article published on 07 August 2013

Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats

scientific journal article

Ulipristal Acetate for Treatment of Symptomatic Uterine Leiomyomas: A Randomized Controlled Trial

scientific article published on 5 February 2018

Umbilical Cord Blood Mesenchymal Stem Cells as an Infertility Treatment for Chemotherapy Induced Premature Ovarian Insufficiency

article

Using Raman spectroscopy to study the onset of labor: a pilot study

Uterine Fibroids: Bridging Genomic Defects and Chronic Inflammation

scientific article published on 3 November 2017

Uterine Fibroids: Burden and Unmet Medical Need

scientific article published on 3 November 2017

Uterine Leiomyoma: New Perspectives on an Old Disease

scientific article published on 3 November 2017

Uterine fibroid therapy: the pharmacokinetic considerations

scientific article published on 02 August 2018

Uterine fibroids in menopause and perimenopause

scientific article published on 01 February 2020

Vision 20/20 for the Second Leap of Reproductive Sciences

scientific article published on 01 January 2020

Vital capacity and patient controlled sevoflurane inhalation result in similar induction characteristics

scientific article published in January 2005

Vitamin D Elicits Anti-Inflammatory Response, Inhibits Contractile-Associated Proteins, and Modulates Toll-Like Receptors in Human Myometrial Cells ⬇️

scientific article published on September 25, 2012

Vitamin D and corticotropin-releasing hormone in term and preterm birth: potential contributions to preterm labor and birth outcome.

scientific article published on 07 August 2017

Vitamin D and uterine fibroids: preclinical evidence is in; time for an overdue clinical study!

scientific article published on 01 January 2020

Vitamin D inhibits proliferation of human uterine leiomyoma cells via catechol-O-methyltransferase ⬇️

scientific article published on August 23, 2010

Vitamin D regulates contractile profile in human uterine myometrial cells via NF-κB pathway

scientific article

Vitamin D, a promising natural compound with anti-uterine fibroid characteristics.

scientific article published on 28 December 2018

Vitamin D3 Ameliorates DNA Damage Caused by Developmental Exposure to Endocrine Disruptors in the Uterine Myometrial Stem Cells of Eker Rats

scientific article published on 12 June 2020

Vitamin D3 Inhibits Wnt/β-Catenin and mTOR Signaling Pathways in Human Uterine Fibroid Cells

scientific article published on 28 January 2016

Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells

scientific article published on 27 June 2013

Vitamins and Uterine Fibroids: Current Data on Pathophysiology and Possible Clinical Relevance

scientific article published on 01 August 2020

Why is Preterm Birth Stubbornly Higher in African-Americans?

scientific article

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