List of works - Hang Yin

A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells

scientific article

Biophysical investigations with MARCKS-ED: dissecting the molecular mechanism of its curvature sensing behaviors

scientific article

Caspases come together over LPS.

scientific article

Chemical Biology Probes for Extracellular Vesicles Facilitate Studies of Neuroinflammation.

scientific article published on 10 December 2015

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles.

scientific article

DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling

scientific article published on 3 February 2015

Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors 7 and 8

scientific article published on 18 November 2019

Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with Antiinflammatory and Anticancer Properties

scientific article published on 05 July 2018

Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities.

scientific article

Discovery of Small-Molecule Cyclic GMP-AMP Synthase Inhibitors

scientific article published on 03 January 2020

Extracellular vesicles derived from ODN-stimulated macrophages transfer and activate Cdc42 in recipient cells and thereby increase cellular permissiveness to EV uptake

scientific article published on 24 July 2019

How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger

scientific article published on 15 July 2020

Kallistatin inhibits vascular inflammation by antagonizing tumor necrosis factor-alpha-induced nuclear factor kappaB activation

scientific article

MARCKS-ED peptide as a curvature and lipid sensor

scientific article published on 29 October 2012

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

scientific article published on 23 November 2018

Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents

scientific article published on 01 January 2021

PNA-based microRNA inhibitors elicit anti-inflammatory effects in microglia cells.

scientific article published on 31 October 2012

Peptides derived from MARCKS block coagulation complex assembly on phosphatidylserine.

scientific article

Photoactivatable Prodrug of Doxazolidine Targeting Exosomes

scientific article published on 13 February 2019

Pyridoxamine is a substrate of the energy-coupling factor transporter HmpT.

scientific article published on 14 July 2015

Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response

scientific article

Rationally Designed Small-Molecule Inhibitors Targeting an Unconventional Pocket on the TLR8 Protein-Protein Interface

scientific article published on 31 March 2020

Regulation of aerobic glycolysis to decelerate tumor proliferation by small molecule inhibitors targeting glucose transporters

scientific article published on 15 May 2020

Sensing of HIV-1 by TLR8 activates human T cells and reverses latency ⬇️

scientific article published on 09 January 2020

Short antimicrobial lipo-α/γ-AA hybrid peptides

scientific article

Small Molecule and Peptide Recognition of Protein Transmembrane Domains.

scientific article

Small-Molecule TLR8 Antagonists via Structure-Based Rational Design

scientific article published on 09 August 2018

Small-molecule inhibition of TLR8 through stabilization of its resting state

scientific article published on 20 November 2017

Specific activation of the TLR1-TLR2 heterodimer by small-molecule agonists.

scientific article

Strategies for targeting protein-protein interactions with synthetic agents.

scientific article

TLR4-dependent fibroblast activation drives persistent organ fibrosis in skin and lung

scientific article published on 12 July 2018

Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists

scientific article published on 16 July 2021

The effects of early rapid corticosteroid reduction on cell-mediated immunity in kidney transplant recipients

scientific article published on 01 October 2010

Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility.

scientific article

p53 alpha-Helix mimetics antagonize p53/MDM2 interaction and activate p53.

scientific article published on June 2005

List of works by Hang Yin

A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells

Biophysical investigations with MARCKS-ED: dissecting the molecular mechanism of its curvature sensing behaviors

Caspases come together over LPS.

Chemical Biology Probes for Extracellular Vesicles Facilitate Studies of Neuroinflammation.

Concise Review: Developing Best-Practice Models for the Therapeutic Use of Extracellular Vesicles.

DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling

Discovery of Novel Small Molecule Dual Inhibitors Targeting Toll-Like Receptors 7 and 8

Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with Antiinflammatory and Anticancer Properties

Discovery of Small Molecules as Multi-Toll-like Receptor Agonists with Proinflammatory and Anticancer Activities.

Discovery of Small-Molecule Cyclic GMP-AMP Synthase Inhibitors

Extracellular vesicles derived from ODN-stimulated macrophages transfer and activate Cdc42 in recipient cells and thereby increase cellular permissiveness to EV uptake

How does an RNA selfie work? EV-associated RNA in innate immunity as self or danger

Kallistatin inhibits vascular inflammation by antagonizing tumor necrosis factor-alpha-induced nuclear factor kappaB activation

MARCKS-ED peptide as a curvature and lipid sensor

Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents

PNA-based microRNA inhibitors elicit anti-inflammatory effects in microglia cells.

Peptides derived from MARCKS block coagulation complex assembly on phosphatidylserine.

Photoactivatable Prodrug of Doxazolidine Targeting Exosomes

Pyridoxamine is a substrate of the energy-coupling factor transporter HmpT.

Rationally Designed Macrocyclic Peptides as Synergistic Agonists of LPS-Induced Inflammatory Response

Rationally Designed Small-Molecule Inhibitors Targeting an Unconventional Pocket on the TLR8 Protein-Protein Interface

Regulation of aerobic glycolysis to decelerate tumor proliferation by small molecule inhibitors targeting glucose transporters

Sensing of HIV-1 by TLR8 activates human T cells and reverses latency ⬇️

Short antimicrobial lipo-α/γ-AA hybrid peptides

Small Molecule and Peptide Recognition of Protein Transmembrane Domains.

Small-Molecule TLR8 Antagonists via Structure-Based Rational Design

Small-molecule inhibition of TLR8 through stabilization of its resting state

Specific activation of the TLR1-TLR2 heterodimer by small-molecule agonists.

Strategies for targeting protein-protein interactions with synthetic agents.

TLR4-dependent fibroblast activation drives persistent organ fibrosis in skin and lung

Tetrasubstituted imidazoles as incognito Toll-like receptor 8 a(nta)gonists

The effects of early rapid corticosteroid reduction on cell-mediated immunity in kidney transplant recipients

Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility.

p53 alpha-Helix mimetics antagonize p53/MDM2 interaction and activate p53.