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List of works by Sebastiano Mercadante

A model of acute symptom control unit: Pain Relief and Palliative Care Unit of La Maddalena Cancer Center

scientific article published on 14 November 2002

A randomized-controlled study of intrathecal versus epidural thoracic analgesia in patients undergoing abdominal cancer surgery

scientific article

Aberrant opioid use behaviour in advanced cancer

scientific article published on 18 December 2020

Addition of a second opioid may improve opioid response in cancer pain: preliminary data

scientific article

Aggressive pharmacological treatment for reversing malignant bowel obstruction

scientific article

Alternative treatments of breakthrough pain in patients receiving spinal analgesics for cancer pain

scientific article published on November 2005

Amitriptyline in neuropathic cancer pain in patients on morphine therapy: a randomized placebo-controlled, double-blind crossover study.

scientific article published on May 2002

An Italian survey on the attitudes in treating breakthrough cancer pain in hospice

scientific article published on 4 July 2010

Application of palliative ventilation: potential and clinical evidence in palliative care

scientific article published on 25 April 2017

Assessing age and gender in studies of breakthrough pain medications

scientific article published on 26 March 2014

Attitudes Among Patients With Advanced Cancer Toward Euthanasia and Living Wills

scientific article published on 15 February 2016

Attitudes of palliative home care physicians towards palliative sedation at home in Italy

scientific article published on 17 January 2017

Attitudes towards end-of-life issues in intensive care unit among Italian anesthesiologists: a nation-wide survey

scientific article published on 15 December 2017

Author's Reply to Johnson and Noble

scientific article published in May 2015

Author's Reply to Kawada

scientific article published on 21 May 2016

Author's Response

Author's Response

scientific article published on 27 September 2018

Author's Response

Author's Response

scientific article published on 26 November 2018

Authors' Reply to Davies et al.

scientific article

Background and episodic breathlessness in advanced cancer patients followed at home

scientific article published on 6 October 2016

Barriers and adherence to pain management in advanced cancer patients

scientific article published on 17 November 2020

Bedside anesthesia for painful procedures in onco-hematology

scientific article published in January 2008

Block of interdigital nerves for cancer pain

scientific article

Breakthrough Cancer Pain in Patients With Abdominal Visceral Cancer Pain

scientific article published on 26 February 2019

Breakthrough Cancer Pain: Preliminary Data of The Italian Oncologic Pain Multisetting Multicentric Survey (IOPS-MS)

scientific article

Breakthrough Cancer Pain: Ten Commandments

scientific article

Breakthrough cancer pain: twenty-five years of study

scientific article published on 19 September 2016

Breakthrough pain and its treatment: critical review and recommendations of IOPS (Italian Oncologic Pain Survey) expert group

scientific article published on 05 October 2015

Breakthrough pain in advanced cancer patients followed at home: a longitudinal study

scientific article

Breakthrough pain in cancer patients: prevalence, mechanisms and treatment options

scientific article published on 08 August 2015

Breakthrough pain: on the road again

scientific article published on 11 February 2009

Burst Ketamine to Reverse Opioid Tolerance in Cancer Pain ⬇️

scientific article published on April 1, 2003

CT-guided neurolytic splanchnic nerve block by an anterior approach

scientific article published in April 2002

Can a phone call be more effective than an intrathecal implanted pump?

scientific article

Cancer pain

scientific article published on June 2013

Cancer pain undertreatment and prognostic factors ⬇️

scientific article published on April 30, 2012

Celiac plexus block for pancreatic cancer pain: factors influencing pain, symptoms and quality of life

scientific article

Celiac plexus block: A reappraisal ⬇️

scientific article published on January 1, 1998

Changes of QTc interval after opioid switching to oral methadone

scientific article

Characteristics of advanced cancer patients who were readmitted to an acute palliative/supportive care unit

scientific article published on 4 February 2017

Characteristics of patients with an unplanned admission to an acute palliative care unit

scientific article published on 3 February 2017

Clarifications on oxycodone–naloxone combination in cancer pain management ⬇️

scientific article published on April 14, 2012

Classification of neuropathic pain in cancer patients: A Delphi expert survey report and EAPC/IASP proposal of an algorithm for diagnostic criteria ⬇️

scientific article published on 2 October 2014

Combined oral prolonged-release oxycodone and naloxone in chronic pain management

scientific article published on 08 December 2012

Controlled sedation for refractory symptoms in dying patients

scientific article

Conversion ratios for opioid switching in the treatment of cancer pain: a systematic review

scientific article published on July 1, 2011

Current knowledge of buprenorphine and its unique pharmacological profile

scientific article published on September 2010

Delirium assessed by Memorial Delirium Assessment Scale in advanced cancer patients admitted to an acute palliative/supportive care unit

scientific article published on 4 April 2017

Dextropropoxyphene versus morphine in Opioid-Naive cancer patients with pain ⬇️

scientific article published on February 1, 1998

Dialogues on complex analgesic strategies for difficult pain syndromes

scientific article

Diarrhea in terminally ill patients: Pathophysiology and treatment ⬇️

scientific article published on May 1, 1995

Does pain intensity predict a poor opioid response in cancer patients?

scientific article

Effect of aging on pain relief in the older cancer patients: pharmacokinetic and pharmacodynamic aspects

scientific article published on 19 February 2016

Effectiveness and tolerability of amidotrizoate for the treatment of constipation resistant to laxatives in advanced cancer patients

scientific article published on 15 September 2010

Effects of red blood cell transfusion on anemia-related symptoms in patients with cancer

scientific article

Efficacy and safety of dual opioid therapy

scientific article published on 29 September 2014

Emergencies in patients with advanced cancer followed at home

scientific article

Emerging drugs for cancer-related pain ⬇️

scientific article published on September 23, 2011

Epidemiology and Characteristics of Episodic Breathlessness in Advanced Cancer Patients: An Observational Study

scientific article published on 25 September 2015

Epidural treatment in advanced cancer patients

scientific article published in May 2004

Episodic (Breakthrough) Pain Prevalence in a Population of Cancer Pain Patients. Comparison of Clinical Diagnoses With the QUDEI—Italian Questionnaire for Intense Episodic Pain

article

Episodic (breakthrough) pain: consensus conference of an expert working group of the European Association for Palliative Care

scientific article

Episodic Breathlessness in Patients with Advanced Cancer: Characteristics and Management.

scientific article published in April 2018

Equipotent doses to switch from high doses of opioids to transdermal buprenorphine

scientific article

Factors Influencing the Clinical Presentation of Breakthrough Pain in Cancer Patients.

scientific article published in June 2018

Factors involved in gastrointestinal bleeding in advanced cancer patients followed at home

scientific article

Fentanyl Buccal Tablet vs. Oral Morphine in Doses Proportional to the Basal Opioid Regimen for the Management of Breakthrough Cancer Pain: A Randomized, Crossover, Comparison Study

scientific article published on 21 August 2015

Fentanyl Pectin Nasal Spray Versus Oral Morphine in Doses Proportional to the Basal Opioid Regimen for the Management of Breakthrough Cancer Pain: A Comparative Study

scientific article published on 18 May 2016

Fentanyl buccal tablet for the treatment of cancer-related breakthrough pain

scientific article published on 31 October 2014

Fentanyl buccal tablets for breakthrough pain in highly tolerant cancer patients: preliminary data on the proportionality between breakthrough pain dose and background dose

scientific article

Fentanyl buccal tablets for the treatment of breakthrough pain

scientific article

Financial distress and its impact on symptom expression in advanced cancer patients

scientific article published on 13 May 2020

Frequency and Indications of Parenteral Nutrition in an Acute Palliative Care Unit

scientific article published on 25 July 2015

Frequency, indications, outcomes, and predictive factors of opioid switching in an acute palliative care unit

scientific article

From "Breakthrough" to "Episodic" Cancer Pain? A European Association for Palliative Care Research Network Expert Delphi Survey Toward a Common Terminology and Classification of Transient Cancer Pain Exacerbations ⬇️

scientific article published on 24 February 2016

Gabapentin in painful ophthalmoplegia

scientific article published in September 2002

High doses of oxycodone-naloxone combination may provide poor analgesia

scientific article

High flow nasal therapy in perioperative medicine: from operating room to general ward

scientific article published on 10 November 2018

High-dose furosemide and small-volume hypertonic saline solution infusion for the treatment of leg edema in advanced cancer patients

scientific article

Hospice care pathways and COVID-19

scientific article published on 17 September 2020

How to use octreotide for malignant bowel obstruction

scientific article published in July 2004

Hyoscine Butylbromide for the Management of Death Rattle: Sooner Rather Than Later

scientific article published on 31 August 2018

Hyperalgesia: an emerging iatrogenic syndrome

scientific article

Improved patient functioning after treatment of breakthrough cancer pain: an open-label study of fentanyl buccal tablet in patients with cancer pain

scientific article published on 4 January 2015

Injustifiable use of gastroprotection in advanced cancer patients

scientific article

Intractable pain and cordotomy

scientific article published on 20 May 2020

Intranasal fentanyl versus fentanyl pectin nasal spray for the management of breakthrough cancer pain in doses proportional to basal opioid regimen

scientific article published on 19 February 2014

Intrathecal treatment in cancer patients unresponsive to multiple trials of systemic opioids

scientific article published in November 2007

Intravenous morphine for breakthrough (episodic-) pain in an acute palliative care unit: a confirmatory study

scientific article

Intravenous morphine for management of cancer pain

scientific article published on May 2010

Intravenous patient-controlled analgesia and management of pain in post-surgical elderly with cancer

scientific article published on 09 April 2010

Is there a ceiling effect of transdermal buprenorphine? Preliminary data in cancer patients

scientific article

Itraconazole-fentanyl interaction in a cancer patient

scientific article published in September 2002

Ketamine: to be or not to be.

scientific article published on January 2013

Local anesthetics for breakthrough pain in patients receiving intrathecal treatment for cancer pain management

scientific article

Localization of the sentinel lymph node in breast cancer: prospective comparison of vital staining and radioactive tracing methods.

scientific article

Low doses of transdermal buprenorphine in opioid-naive patients with cancer pain: a 4-week, nonrandomized, open-label, uncontrolled observational study

scientific article published in October 2009

Low doses of transdermal fentanyl in opioid-naive patients with cancer pain

scientific article

Low morphine doses in opioid-naive cancer patients with pain

scientific article published in March 2006

Management of painful bone metastases

scientific article

Managing Breakthrough Pain ⬇️

scientific article published on August 1, 2011

Managing difficult pain conditions in the cancer patient

scientific article published on February 2014

Medical treatment for inoperable malignant bowel obstruction: a qualitative systematic review

scientific article published on February 2007

Methadone as first line opioid in cancer pain management: a systematic review

scientific article published on 31 October 2017

Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations

scientific article published on 15 September 2015

Naloxone in treating central adverse effects during opioid titration for cancer pain

scientific article

New drugs for pain management in advanced cancer patients

scientific article published on 5 March 2017

Non pharmacological interventions and non-fentanyl pharmacological treatments for breakthrough cancer pain: A systematic and critical review

scientific article published on 23 December 2017

Nurse-based monitoring and management of breakthrough pain in an acute pain relief and palliative care unit

scientific article published on August 2016

Obviousness in the dying patient

scientific article published on 28 October 2016

Octreotide for malignant bowel obstruction: Twenty years after ⬇️

scientific article published on January 25, 2012

Octreotide for malignant bowel obstruction: commentary on Currow et al.

scientific article published on 8 April 2015

Octreotide in the treatment of diarrhoea induced by coeliac plexus block ⬇️

scientific article published on May 1, 1995

Ondansetron in Nausea and Vomiting Induced by Spinal Morphine ⬇️

scientific article published on October 1, 1998

Opioid Analgesics Adverse Effects: The Other Side of the Coin

scientific article published on 01 January 2019

Opioid combination: rationale and possible clinical applications

scientific article published on October 2013

Opioid consumption in Italy: industry is not necessarily business--look at the effects

scientific article

Opioid escalation in patients with cancer pain: the effect of age.

scientific article published on November 2006

Opioid metabolism and clinical aspects

scientific article

Opioid plasma concentrations during a switch from transdermal fentanyl to methadone

scientific article

Opioid prescription in Italy: new law, no effect

scientific article

Opioid responsiveness in patients with advanced head and neck cancer ⬇️

scientific article published on September 1, 1998

Opioid switching and burst ketamine to improve the opioid response in patients with movement-related pain due to bone metastases

scientific article

Opioid switching in cancer pain: From the beginning to nowadays

scientific article

Opioid switching in patients with advanced cancer followed at home. A retrospective analysis

scientific article published on 25 October 2012

Opioid switching: a systematic and critical review

scientific article

Opioid titration in cancer pain: a critical review

scientific article published on 28 February 2007

Opioid-induced hyperalgesia after rapid titration with intravenous morphine: Switching and re-titration to intravenous methadone

scientific article

Opioid-induced or pain relief-reduced symptoms in advanced cancer patients?

scientific article published on February 2006

Opioid-sparing effect of diclofenac in cancer pain ⬇️

scientific article published on July 1, 1997

Opioids and renal function

scientific article published on February 2004

Optimization of opioid therapy for preventing incident pain associated with bone metastases

scientific article

Options for Treating Pain in Cancer Patients with Dysphagia

scientific article published on March 2017

Oral trasmucosal fentanyl citrate for breakthrough pain treatment in cancer patients ⬇️

scientific article published on March 19, 2012

Orphan symptoms in advanced cancer patients followed at home

scientific article

Outcome of opioid switching 4 weeks after discharge from a palliative care unit

scientific article

Oxycodone extended release capsules for the treatment of chronic pain

scientific article

Pain in patients with lung cancer: pathophysiology and treatment

scientific article published on 16 December 2009

Pain mechanisms involved and outcome in advanced cancer patients with possible indications for celiac plexus block and superior hypogastric plexus block

scientific article published on May 2002

Palliative care in advanced cancer patients: how and when? And where?

scientific article published on 17 May 2012

Palliative care in intensive care units: why, where, what, who, when, how

article by Sebastiano Mercadante et al published 16 August 2018 in BMC Anesthesiology

Palliative sedation in patients with advanced cancer followed at home: a prospective study

scientific article

Palliative ventilatory support: same knowledge, different goal.

scientific article published in March 2018

Parenteral routes for opioid administration in cancer pain management

scientific article published on 19 July 2016

Parenteral versus enteral nutrition in cancer patients: indications and practice ⬇️

scientific article published on March 1, 1998

Patients' and relatives' perceptions about intravenous and subcutaneous hydration

scientific article

Pattern and characteristics of advanced cancer patients admitted to hospices in Italy

scientific article published on 4 October 2012

Peritoneal catheter for continuous drainage of ascites in advanced cancer patients

scientific article

Personalized Goal for Dyspnea and Clinical Response in Advanced Cancer Patients

Personalized goal for dyspnea and clinical response in advanced cancer patients

Pharmacological management of cancer pain in children

scientific article published on 24 January 2014

Pharmacological management of cancer pain in the elderly

scientific article published on January 2007

Pharmacotherapy for Breakthrough Cancer Pain

scientific article published on January 22, 2012

Physicians' Attitudes Toward Euthanasia and Assisted Suicide in Italy

article

Pilocarpine as an adjuvant to morphine therapy ⬇️

scientific article published on January 31, 1998

Predictive factors and opioid responsiveness in cancer pain ⬇️

scientific article published on April 1, 1998

Prevalence and treatment of cancer pain in Italian oncological wards centres: a cross-sectional survey

scientific article published on 14 May 2008

Prevalence of delirium in advanced cancer patients in home care and hospice and outcomes after 1 week of palliative care

scientific article published on 5 October 2017

Prevalence of opioid-related dysuria in patients with advanced cancer having pain

scientific article published on 16 August 2010

Prolonged uncontrolled pain, psychological distress, and opioid escalation

scientific article

Prospects and challenges in opioid analgesia for pain management

scientific article published on 19 July 2011

Randomized double-blind, double-dummy crossover clinical trial of oral tramadol versus rectal tramadol administration in opioid-naive cancer patients with pain

scientific article

Rapid switching between transdermal fentanyl and methadone in cancer patients

scientific article published in August 2005

Rapid titration with intravenous morphine for severe cancer pain and immediate oral conversion

scientific article published on July 2002

Re: Rauck et al. Long-term intrathecal opioid therapy with a patient-activated, implanted delivery system for the treatment of refractory cancer pain. J Pain. 2003 Oct;4(8):441-7.

scientific article

Refractory death rattle: deep aspiration facilitates the effects of antisecretory agents

scientific article

Relationship between background cancer pain, breakthrough pain, and analgesic treatment: a preliminary study for a better interpretation of epidemiological and clinical studies

scientific article published on 24 April 2013

Report of the clinical protocol committee: development of randomized trials for malignant bowel obstruction

scientific article published on 4 June 2007

Safety and effectiveness of intravenous morphine for episodic (breakthrough) pain using a fixed ratio with the oral daily morphine dose

scientific article

Scoring the effect of radiotherapy for painful bone metastases

scientific article published on 30 March 2006

Sexual issues in early and late stage cancer: a review

scientific article published on 18 March 2010

Sexuality in patients with advanced cancer: a prospective study in a population admitted to an acute pain relief and palliative care unit

scientific article published in May 2011

Sleep Disturbances in Patients With Advanced Cancer in Different Palliative Care Settings

scientific article published on 23 August 2015

Sleep disorders in advanced cancer patients: prevalence and factors associated

scientific article

Spinal analgesia for advanced cancer patients: an update

scientific article published on 17 June 2011

Stop and go strategy for opioid switching requires flexibility ⬇️

scientific article published on February 1, 2012

Surgical treatment of early breast cancer in day surgery.

scientific article published in September 2007

Switching Methadone: A 10-Year Experience of 345 Patients in an Acute Palliative Care Unit ⬇️

scientific article published on February 23, 2012

Switching from oxycodone to methadone in advanced cancer patients

scientific article

Switching from transdermal drugs: an observational "N of 1" study of fentanyl and buprenorphine

scientific article

Switching to methadone: 'ad libitum' or fixed dose ratio?

scientific article published in January 2004

Sympathetic blocks and disease progression modifying pain mechanisms

scientific article published in November 2003

Sympathetic blocks for visceral cancer pain management: A systematic review and EAPC recommendations

scientific article published on August 2015

Symptom Expression in Patients with Advanced Cancer Admitted to an Acute Supportive/Palliative Care Unit With and Without Delirium

scientific article published on 24 October 2018

Symptom burden in mesothelioma patients admitted to home palliative care

scientific article published on 17 August 2016

Symptom expression in advanced cancer patients admitted to hospice or home care with and without delirium

scientific article published on 17 October 2018

Tapentadol in cancer pain management: a prospective open-label study

scientific article published on 26 October 2012

Temporary Drainage of Symptomatic Malignant Ascites by a Catheter Inserted Under Computerized Tomography ⬇️

scientific article published on June 1, 1998

The anesthesiologist and end-of-life care

scientific article published on June 2012

The bad luck of being old.

scientific article published on 30 January 2015

The clash between palliative care and COVID-19

scientific article published on 14 August 2020

The effect of age on opioid switching to methadone: a systematic review

scientific article published on 21 February 2012

The effects of alcoholism and smoking on advanced cancer patients admitted to an acute supportive/palliative care unit

scientific article published on 16 February 2017

The long and winding road of non steroidal antinflammatory drugs and paracetamol in cancer pain management: a critical review

scientific article published on 08 February 2013

The lower the expectations in controlling the symptoms of advanced cancer patients, the better the clinical response

scientific article published on 14 September 2020

The pain, the oncologist

scientific article published on 6 June 2014

The poor use of methadone in Italian hospices

scientific article published on 16 March 2013

The prevalence of constipation at admission and after 1 week of palliative care: a multi-center study

scientific article

The role of OROS hydromorphone in the management of cancer pain

scientific article published on 20 October 2009

The role of tapentadol as a strong opioid in cancer pain management: a systematic and critical review

scientific article published on 14 September 2017

The role of transdermal buprenorphine in the treatment of cancer pain: an expert panel consensus

scientific article published on June 2009

The use of bisphosphonates in the management of bone metastatic prostate cancer

scientific article

The use of fentanyl buccal tablets as breakthrough medication in patients receiving chronic methadone therapy: an open label preliminary study

scientific article published on 30 September 2010

The use of fentanyl buccal tablets for breakthrough pain by using doses proportional to opioid basal regimen in a home care setting

scientific article published on 7 April 2013

The use of high doses of OROS hydromorphone in an acute palliative care unit ⬇️

scientific article published on November 14, 2011

The use of high doses of oxycodone in an acute palliative care unit

scientific article published on 8 September 2010

The use of low doses of a sublingual fentanyl formulation for breakthrough pain in patients receiving low doses of opioids

scientific article published on 15 October 2016

The use of opioids for breakthrough pain in acute palliative care unit by using doses proportional to opioid basal regimen

scientific article published on May 2010

The use of opioids for treatment of cancer pain

scientific article

The use of opioids in the last week of life in an acute palliative care unit

scientific article published on 3 May 2010

The use of rapid onset opioids for breakthrough cancer pain: The challenge of its dosing ⬇️

scientific article published on 06 January 2011

The use of sublingual fentanyl for breakthrough pain by using doses proportional to opioid basal regimen

scientific article published on 19 August 2013

Tools for identifying cancer pain of predominantly neuropathic origin and opioid responsiveness in cancer patients

scientific article

Topical amitriptyline and ketamine for the treatment of neuropathic pain

scientific article published on 21 October 2015

Tracheal stent to repair tracheal laceration after a double-lumen intubation

scientific article published in September 2012

Treating breakthrough pain in oncology

scientific article published on 26 February 2018

Treatment of pain in chronic bowel subobstruction with self-administration of methadone ⬇️

scientific article published on July 1, 1997

US Food and Drug Administration's Risk Evaluation and Mitigation Strategy for extended-release and long-acting opioids: pros and cons, and a European perspective

scientific article published on December 2012

Unexpected Death on an Acute Palliative Care Unit

scientific article published on 14 October 2015

Use of opioid analgesics in the treatment of cancer pain: evidence-based recommendations from the EAPC.

scientific article

When the game is hard, more complex weapons are needed

scientific article published in 2022

When the progression of disease lowers opioid requirement in cancer patients

scientific article published on January 2010

Why are our patients still suffering pain?

scientific article

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