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List of works by Blake Wiedenheft

A CRISPR method for genome engineering

scientific article

A Conserved Structural Chassis for Mounting Versatile CRISPR RNA-Guided Immune Responses

scientific article published on 28 May 2015

A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells.

scientific article published on 30 April 2018

AcrIF9 tethers non-sequence specific dsDNA to the CRISPR RNA-guided surveillance complex

scientific article published on 01 June 2020

An archaeal antioxidant: characterization of a Dps-like protein from Sulfolobus solfataricus

scientific article

Bacteriophage Cooperation Suppresses CRISPR-Cas3 and Cas9 Immunity

scholarly article by Adair L Borges et al published 9 August 2018 in Cell

CRISPR RNA-guided autonomous delivery of Cas9

scientific article published on 31 December 2018

CRISPR control of virulence in Pseudomonas aeruginosa

scientific article published on 13 January 2017

CRISPR-mediated adaptive immune systems in bacteria and archaea

scientific article published on 11 March 2013

Cas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activity

scientific article

Comparative genomic analysis of hyperthermophilic archaeal Fuselloviridae viruses

scientific article published on February 2004

Conformational Dynamics of DNA Binding and Cas3 Recruitment by the CRISPR RNA-Guided Cascade Complex

scientific article published on 16 October 2017

Conformational regulation of CRISPR-associated nucleases

scientific article

Crystal structure of F-93 from Sulfolobus spindle-shaped virus 1, a winged-helix DNA binding protein

scientific article

Dps-like protein from the hyperthermophilic archaeon Pyrococcus furiosus

scientific article

Fitting CRISPR-associated Cas3 into the helicase family tree

scientific article published on 28 January 2014

Foreign DNA acquisition by the I-F CRISPR-Cas system requires all components of the interference machinery

scientific article

Hot crenarchaeal viruses reveal deep evolutionary connections

scientific article

In defense of phage: viral suppressors of CRISPR-mediated adaptive immunity in bacteria ⬇️

scientific article

Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events

scientific article published on 25 November 2017

Mechanism of CRISPR-RNA guided recognition of DNA targets in Escherichia coli

scientific article

Mechanism of Foreign DNA Selection in a Bacterial Adaptive Immune System

scientific article

Mechanism of foreign DNA recognition by a CRISPR RNA-guided surveillance complex from Pseudomonas aeruginosa

scientific article

Multiple mechanisms for CRISPR-Cas inhibition by anti-CRISPR proteins

scientific article

Native tandem and ion mobility mass spectrometry highlight structural and modular similarities in clustered-regularly-interspaced shot-palindromic-repeats (CRISPR)-associated protein complexes from Escherichia coli and Pseudomonas aeruginosa

scientific article

Programmed Self-Assembly of an Active P22-Cas9 Nanocarrier System

scientific article

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions ⬇️

scientific article published on May 2, 2011

Repair of CRISPR-guided RNA breaks enables site-specific RNA excision in human cells

scientific article published on 25 April 2024

Sequence- and Structure-Specific RNA Processing by a CRISPR Endonuclease

scientific article

SnapShot: CRISPR-RNA-guided adaptive immune systems

scientific article published on September 2015

Something old, something new, something borrowed; how the thermoacidophilic archaeon Sulfolobus solfataricus responds to oxidative stress

scientific article

Structural basis for CRISPR RNA-guided DNA recognition by Cascade

scientific article

Structural basis for DNase activity of a conserved protein implicated in CRISPR-mediated genome defense

scientific article

Structural basis for promiscuous PAM recognition in type I-E Cascade from E. coli

scientific article

Structural biology. Crystal structure of the CRISPR RNA-guided surveillance complex from Escherichia coli

scientific article

Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex

scientific article published on March 2017

Structure of D-63 from sulfolobus spindle-shaped virus 1: surface properties of the dimeric four-helix bundle suggest an adaptor protein function

scientific article

Structure of the DPS-like protein from Sulfolobus solfataricus reveals a bacterioferritin-like dimetal binding site within a DPS-like dodecameric assembly

scientific article

Structures of the RNA-guided surveillance complex from a bacterial immune system

scientific article

Surveillance and Processing of Foreign DNA by the Escherichia coli CRISPR-Cas System

scientific article

The CRISPR RNA-guided surveillance complex in Escherichia coli accommodates extended RNA spacers

scientific article published on 12 May 2016

The Interfaces of Genetic Conflict Are Hot Spots for Innovation

scientific article published on 12 January 2017

The history and market impact of CRISPR RNA-guided nucleases

scientific article

Type I-F CRISPR-Cas provides protection from DNA, but not RNA phages

scientific article published on 22 October 2019

Unravelling the structural and mechanistic basis of CRISPR-Cas systems

scientific article

Using Cryoem to Understand How Phages Evade Bacterial CRISPR Defense System

Virus movement maintains local virus population diversity

scientific article

Viruses of hyperthermophilic Archaea ⬇️

scientific article published on September 1, 2003

X-ray structure determination using low-resolution electron microscopy maps for molecular replacement

scientific article

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